Sequence details NCBI ID: XM_004865768.1 (Coding sequence)   Best Hit

Details from NCBI annotation

Gene Symbol Sirt6
Gene Name sirtuin 6, transcript variant X4
Entrez Gene ID 101706114

This gene is present in the GenAge database and has been identified as potentially important to ageing in humans.

Database interlinks

Part of NW_004624828.1 (Scaffold)

For more information consult the page for NW_004624828.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

SIRT6 ENSG00000077463 (Human)

Gene Details

sirtuin 6

External Links

Gene Match (Ensembl Protein ID: ENSP00000337332, Human)

Protein Percentage 86.64%
CDS Percentage 84.25%
Ka/Ks Ratio 0.06364 (Ka = 0.0697, Ks = 1.0956)

Sirt6 ENSMUSG00000034748 (Mouse)

Gene Details

sirtuin 6 (silent mating type information regulation 2, homolog) 6 (S. cerevisiae)

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000048971, Mouse)

Protein Percentage 81.07%
CDS Percentage 78.21%
Ka/Ks Ratio 0.06233 (Ka = 0.1092, Ks = 1.7512)

Sirt6 ENSRNOG00000006393 (Rat)

Gene Details

sirtuin 6 (Sirt6), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000008758, Rat)

Protein Percentage 83.33%
CDS Percentage 79.11%
Ka/Ks Ratio 0.05596 (Ka = 0.0958, Ks = 1.7124)

Genome Location

Sequence Coding sequence

Length: 891 bp    Location: 5442020..5449549   Strand: +
Raw sequence   
>XM_004865768.1
ATGCGGATAAGGGCAAGTGTGGCCTCCCCGAGGGGCCCGCACGGTGTGTGGACCATGGAGGAGCGGGGTCTGGCGCCCAAGTTCGACACGACCTTTGAGAGCGCGCGGCCCACGCGCACACACATGGCGCTGGTGCAGCTGGAGCGCGTGGGGCTGCTGCACTTCCTCGTCAGCCAGAACGTGGACGGGCTGCATGTGCGCTCCGGCTTCCCCAGGGACAAACTGGCAGAGCTGCATGGGAACATGTTCGTAGAAGAATGTGCCAAGTGTAAGACGCAGTACGTCCGGGACACGGTCGTGGGCACCATGGGCCTCAAGGCCACCGGGAGGTTCTGCACAGTGGCCAAGGCGCGGGGACTGCGGGCTTGCCGGGGGGAGCTGAGAGACACCATCCTGGACTGGGAAGATGCCCTGCCTGAGCGGGATCTGGCTCTCGCCGACGAGGCCAGCAGGAACGCGGACCTGTCCATCACCCTGGGGACCTCCCTGCAGATCCGGCCCAGCGGGAACCTGCCCCTGGCCACCAAACGCCGGGGCGGCCGCCTGGTCATTGTGAACCTGCAGCCCACCAAGCACGACCGCCAGGCTGACTTGCGCATCCACGGCTACGTGGACGATGTGATGGCTGGGCTCATGCGACACCTGGGGCTGGACATCCCCGCCTGGCACGGGCCCCGAGTGCTGGAAAGGGCCCTTCCCCCACTGCCCCGGCCTCCCGCACCCAAGCTGGAGCAGAAGGATGACAAGGGTGAGGACTCTACAGCCCAGCTCAATGGCTCTGCACCCACCCAGCCCAAGCCAGAGCCCAGCAGCCCCAAACTGGAGCGGCCCGAGAGCCTGGCCCCTTGCAGGCCCCCCAAGAGGCTGAAGGCTGAGGCAGTGCCCAGCTGA

Related Sequences

XP_004865825.1 Protein

Sirt6 PREDICTED: NAD-dependent protein deacetylase sirtuin-6 isoform X4 [Heterocephalus glaber]

Length: 296 aa      
>XP_004865825.1
MRIRASVASPRGPHGVWTMEERGLAPKFDTTFESARPTRTHMALVQLERVGLLHFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRFCTVAKARGLRACRGELRDTILDWEDALPERDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRQADLRIHGYVDDVMAGLMRHLGLDIPAWHGPRVLERALPPLPRPPAPKLEQKDDKGEDSTAQLNGSAPTQPKPEPSSPKLERPESLAPCRPPKRLKAEAVPS