Details from NCBI annotation

Gene Symbol Smpd3
Gene Name sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II), transcript variant X4
Entrez Gene ID 101722154

Database interlinks

Part of NW_004624746.1 (Scaffold)

For more information consult the page for NW_004624746.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

SMPD3 ENSCPOG00000015388 (Guinea pig)

Gene Details

sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000013873, Guinea pig)

Protein Percentage 92.53%
CDS Percentage 92.02%
Ka/Ks Ratio 0.12759 (Ka = 0.0355, Ks = 0.2783)

SMPD3 ENSG00000103056 (Human)

Gene Details

sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)

External Links

Gene Match (Ensembl Protein ID: ENSP00000219334, Human)

Protein Percentage 89.92%
CDS Percentage 87.63%
Ka/Ks Ratio 0.07984 (Ka = 0.0487, Ks = 0.6099)

Smpd3 ENSMUSG00000031906 (Mouse)

Gene Details

sphingomyelin phosphodiesterase 3, neutral

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000069255, Mouse)

Protein Percentage 91.6%
CDS Percentage 87.53%
Ka/Ks Ratio 0.0716 (Ka = 0.0414, Ks = 0.5779)

Smpd3 ENSRNOG00000000257 (Rat)

Gene Details

sphingomyelin phosphodiesterase 3, neutral membrane (Smpd3), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000000274, Rat)

Protein Percentage 91.76%
CDS Percentage 88.04%
Ka/Ks Ratio 0.08028 (Ka = 0.0417, Ks = 0.519)

Genome Location

Sequence Coding sequence

Length: 1974 bp    Location: 17924209..17948468   Strand: +
>XM_004842971.1
ATGGTTTTGTACACAGCCCCCTTTCCTAATAGCTGTCTGTGCGCCCTGCACGCAGTGTCCTGGGCTCTCATCTTCCCATGTTACTGGCTGGTGGACAGGCTCACAGCCTCCTTCCTACCCACCACTTATGAGAAGCGACAGCGCGCGGACGACCCGTGCTACCTGCACCTGCTCTGCACTGCCTTCTTCACGCCCATCTACCTGGCCCTCCTCCTGGCCTCGCTGCCCTTTGCCTTTCTTGGGTTCCTCTTCTGGTCTCCCCTGCAGTCTGCCCGCCGGCCCTACATCTACTCACGGCTGGAGGACAAGAGCCCAGCCGGTGGGGCAGCCCTGCTTGGTGAATGGAAGGGTACAGGGGCTGGCAAAAGCTTCTGCTTCGCCACCGCCAATCTCTGTCTCCTCCCTGACTCACTGGCCAGGCTCAACAACGTCTTCAACACCCAAGCACGAGCCAAAGAGATCGGGCAGAGAATCCGCAATGGCGCTGCGCGTCCCCAGATCAAAATCTACATCGATTCACCCACGAACACCTCCATCAGTGCAGCTAGCTTCAGCAGCCTGGTGTCCCCACAAGGCAGTGATAGCGGGGCCAGGGCTGTCCCTGTGAGCATTAAGAGGACATCCTCTGTGGAATACAAGGGCGATGGCGGGCATCACCCCAGCGATGAGGCTGCCAATGGGTCTGCCCCTGGGGACCTGGCTGACAGTGGCAGCCTTGAGGATGCCTGCATTGTCCGCATCAGTGGCGAGGAGGGGGGGCGGCCACCTGAAGCTGAAGACCCTGCCACTGGGAACCAAGCCAGGAACGGGGCCAGCGGGGGCCCAAAGGGCCAGACACCCAACCACAATCAGCGGGATGGGGACTCTAGCAGCCTGGGCAGCCCTTCCGCCTCCAGGGAGTCCCTGGTGAAAGCTCGAGCCGGGCCGGACAGCAGTGGCAGTGGGGACCCGGGGGCCAACAACAAGCTCCTGTACAGGGCCTCGGTGGTGAAGAAGGCAGCCTCGCGCAGGAGGCGGCACCCTGATGAGGCCTTTGACCACGAGGTCTCAGCCTTCTTCCCTGCCAACCTGGACTTCCTGTGCCTGCAGGAGGTGTTTGATAAGCGGGCAGCTGCCAAGTTGAAAGAGCAGCTGCATGGCTACTTTGAGTACATCCTGTACGACGTTGGGGTCTATGGCTTCCACGGCTGCTGCAGTTTCAAGTGTCTCAACAGCGGCCTCTTCTTTGCAAGCCGCTACCCCATCATGGACGTGGCCTATCACTGTTACCCCAACGGTCGCGGCTCCGATGCCATGGCCTCTAAGGGAGCGCTGTTTCTCAAGGTGCAGGTGGGAAGCACACCTCAGGACCAAAGAATCGTTGGGTACATCGCCTGCACACATCTGCACGCCCTACCAGAGGACAGCGCCATCCGCTGTGAGCAGCTGGACCTGCTTCAGGACTGGCTGGCTGATTTCCGAAAATCTACCTCCTCCTCCAGCACAGCCAACCCCGAGGAGCTGGTGGCGTTTGACGTCATCTGCGGAGATCTGAACTTTGACAATTGCTCCTCAGATGACAAGCTGGAGCAGCAGCACTCCCTGTTTACACGTTACAAGGACCCCTGCCGCCTGGGGCCTGGGGAGGAGAAGCCGTGGGCCATCGGTACCCTGTTGGACACAAATGGCCTCTATGATGAGGATGTGTGCACCCCTGACAATCTGCAAAAGGTCCTGGAAAGCGAGGAAGGCCGCCGGGAGTACCTGGCTTTCCCCACCAGCAAGAGCCCAGGAGGTGGCCAGAAGGGGCGGAAGGACCTGCTGAAAGGCAACGGCCGTCGAATTGATTACATGCTACATGCTGAGGAGGGCCTATGCCCTGACTGGAAGGCTGAGGTGGAAGAATACAGTTTTATCACCCAGCTATCCGGCCTGACTGACCACCTCCCTGTGGCCATGCGGCTGATGGTGTCTGCAGGGGAGGAGGAGGCGTAG

Related Sequences

XP_004843028.1 Protein

Smpd3 PREDICTED: sphingomyelin phosphodiesterase 3 isoform X4 [Heterocephalus glaber]

Length: 657 aa      View alignments
>XP_004843028.1
MVLYTAPFPNSCLCALHAVSWALIFPCYWLVDRLTASFLPTTYEKRQRADDPCYLHLLCTAFFTPIYLALLLASLPFAFLGFLFWSPLQSARRPYIYSRLEDKSPAGGAALLGEWKGTGAGKSFCFATANLCLLPDSLARLNNVFNTQARAKEIGQRIRNGAARPQIKIYIDSPTNTSISAASFSSLVSPQGSDSGARAVPVSIKRTSSVEYKGDGGHHPSDEAANGSAPGDLADSGSLEDACIVRISGEEGGRPPEAEDPATGNQARNGASGGPKGQTPNHNQRDGDSSSLGSPSASRESLVKARAGPDSSGSGDPGANNKLLYRASVVKKAASRRRRHPDEAFDHEVSAFFPANLDFLCLQEVFDKRAAAKLKEQLHGYFEYILYDVGVYGFHGCCSFKCLNSGLFFASRYPIMDVAYHCYPNGRGSDAMASKGALFLKVQVGSTPQDQRIVGYIACTHLHALPEDSAIRCEQLDLLQDWLADFRKSTSSSSTANPEELVAFDVICGDLNFDNCSSDDKLEQQHSLFTRYKDPCRLGPGEEKPWAIGTLLDTNGLYDEDVCTPDNLQKVLESEEGRREYLAFPTSKSPGGGQKGRKDLLKGNGRRIDYMLHAEEGLCPDWKAEVEEYSFITQLSGLTDHLPVAMRLMVSAGEEEA