Sequence details NCBI ID: XM_004875039.1 (Coding sequence)   Best Hit

Details from NCBI annotation

Gene Symbol Mdm2
Gene Name MDM2 oncogene, E3 ubiquitin protein ligase, transcript variant X2
Entrez Gene ID 101724821

This gene is present in the GenAge database and has been identified as potentially important to ageing in humans.

Database interlinks

Part of NW_004624948.1 (Scaffold)

For more information consult the page for NW_004624948.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

MDM2 ENSCPOG00000004323 (Guinea pig)

Gene Details

MDM2 oncogene, E3 ubiquitin protein ligase

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000003899, Guinea pig)

Protein Percentage 92.45%
CDS Percentage 93.27%
Ka/Ks Ratio 0.17734 (Ka = 0.0374, Ks = 0.2111)

MDM2 ENSG00000135679 (Human)

Gene Details

MDM2 oncogene, E3 ubiquitin protein ligase

External Links

Gene Match (Ensembl Protein ID: ENSP00000417281, Human)

Protein Percentage 91.65%
CDS Percentage 91.99%
Ka/Ks Ratio 0.13988 (Ka = 0.0408, Ks = 0.2918)

Mdm2 ENSMUSG00000020184 (Mouse)

Gene Details

transformed mouse 3T3 cell double minute 2

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000020408, Mouse)

Protein Percentage 83.64%
CDS Percentage 83.02%
Ka/Ks Ratio 0.11338 (Ka = 0.0856, Ks = 0.755)

Mdm2 ENSRNOG00000006304 (Rat)

Gene Details

p53 E3 ubiquitin protein ligase (Mdm2), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000063449, Rat)

Protein Percentage 83.41%
CDS Percentage 83.11%
Ka/Ks Ratio 0.1205 (Ka = 0.0918, Ks = 0.7619)

Genome Location

Sequence Coding sequence

Length: 1482 bp    Location: 475555..446946   Strand: -
Raw sequence   
>XM_004875039.1
ATGTGCAATACCAACATGTCTGTGTCTACTGATGGTGCTGTAAGCACCTCACAGATTCCCGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCCTTGCTTCTGAAGTTGTTAAAGTCTGTTGGTGCACAAAAAGACACTTACACTATGAAAGAGGTCATATTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGAGTACCAAGTTTTTCTGTGAAAGAGCACAGGAAAATATATACAATGATCTACAGAAACTTGACAGTAGTCAATCAACAGGAACCATCAGACTCTGGCACATCTGTGAGTGAGAGCAGGTGTCACCTTGAAGATGAGAGTGAACAAAAGGACCCTGGGCAAGAGCAAGAGCTACAAGAAGAAAAACCTTCATCTTCAGATTTGGTTTCTAGGCCGTCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTGTCTGGTGAACGACAAAGAAAACGCCACAAGTCAGATAGTATTTCTCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTGATAAGGGAGCTATGTTGTGAAAGAAGTAACAGCAGTGAATCGACAGAGACTCCATCAAATCTGGATCTGGATGATGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAATTCAGTGTAGAATTTGAAGTTGAATCTCTTGACTCAGAAGATTATAGTCTTAGTGAAGAAGGACAAGACCTCTCAGATGAAGATGATGAGGTATATCGAGTTACTGTGTATCAGGCAGGGGAAAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAGTGTACTTCATGCAATGAAATGAATCCTCCCCTTCCGTCGCATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAGGGGGAACTCCCTGAGAAAGCCAAATTCGAAAACTCAACACAGGCAAAAGAGGGCTTGGATGTGCCCGATGGTAAAAAACCTGCGACAAATGATTCCAGAGAGTCATGTATTGATGAAGATAATGATAAAGTCACACAAGCCTCCCAGTCACAAGAAAGTGAGGACTATTCTCAGCCATCAACTTCTGGTAGCATTATTAATAGCAGCCAGGAAGATGTTAAGGAGTTGGAGAAGGAAGAAACACAAGAGAAAGAAGAAAGTGTGGAATCTAGTTTTCCCCTTAATGCCATTGAACCTTGTGTGATTTGCCAAGGTCGACCTAAAAATGGTTGCATTGTTCATGGCAAAACAGGACATCTTATGTCATGTTTTACCTGTGCAAAGAAGCTAAAGAAAAGAAATAAGCCCTGCCCAGTATGCAGACAACCAATTCAAATGATTGTGCTAACTTATTTCAATTAG

Related Sequences

XP_004875096.1 Protein

Mdm2 PREDICTED: E3 ubiquitin-protein ligase Mdm2 isoform X2 [Heterocephalus glaber]

Length: 493 aa      View alignments
>XP_004875096.1
MCNTNMSVSTDGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLTVVNQQEPSDSGTSVSESRCHLEDESEQKDPGQEQELQEEKPSSSDLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIRELCCERSNSSESTETPSNLDLDDGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQDLSDEDDEVYRVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGELPEKAKFENSTQAKEGLDVPDGKKPATNDSRESCIDEDNDKVTQASQSQESEDYSQPSTSGSIINSSQEDVKELEKEETQEKEESVESSFPLNAIEPCVICQGRPKNGCIVHGKTGHLMSCFTCAKKLKKRNKPCPVCRQPIQMIVLTYFN