Sequence details NCBI ID: XM_004867917.1 (Coding sequence)   Best Hit

Details from NCBI annotation

Gene Symbol Itch
Gene Name itchy E3 ubiquitin protein ligase
Entrez Gene ID 101711522

Database interlinks

Part of NW_004624842.1 (Scaffold)

For more information consult the page for NW_004624842.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

ITCH ENSCPOG00000013787 (Guinea pig)

Gene Details

itchy E3 ubiquitin protein ligase

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000012422, Guinea pig)

Protein Percentage 97.45%
CDS Percentage 95.75%
Ka/Ks Ratio 0.06317 (Ka = 0.0111, Ks = 0.1752)

ITCH ENSG00000078747 (Human)

Gene Details

itchy E3 ubiquitin protein ligase

External Links

Gene Match (Ensembl Protein ID: ENSP00000262650, Human)

Protein Percentage 97.33%
CDS Percentage 94.08%
Ka/Ks Ratio 0.05183 (Ka = 0.0125, Ks = 0.2421)

Itch ENSMUSG00000027598 (Mouse)

Gene Details

itchy, E3 ubiquitin protein ligase

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000105307, Mouse)

Protein Percentage 95.36%
CDS Percentage 90.76%
Ka/Ks Ratio 0.05442 (Ka = 0.0226, Ks = 0.4152)

Itch ENSRNOG00000018099 (Rat)

Gene Details

itchy E3 ubiquitin protein ligase (Itch), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000024411, Rat)

Protein Percentage 95.42%
CDS Percentage 90.33%
Ka/Ks Ratio 0.05177 (Ka = 0.0225, Ks = 0.4354)

Genome Location

Sequence Coding sequence

Length: 2589 bp    Location: 4977746..4842284   Strand: -
Raw sequence   
>XM_004867917.1
ATGTCTGACAGTGGATCACAACTTGGTTCAATGGGTAGCCTGACCATGAAATCACAACTTCAAATCACTGTCCTCTCAGCAAAACTTAAAGAAAATAAAAAGAATTGGTTTGGACCAAGTCCTTATGTGGAAGTGACAGTAGACGGACAGTCAAAGAAGACAGAAAAATGTAATAATACGAATAGCCCCAAATGGAAGCAGCCACTTACAGTTATCGTTACCCCTGTGAGTAAATTACATTTTCGTGTGTGGAGTCACCAGACACTGAAATCTGATGTTTTGTTGGGAACTGCTGCAGTAGATATATATGAAACCTTAAAGTCGAACAATATGAAACTTGAAGAAGTGGTTGTGTCTTTGCAGCTTATAGGTGACAAAGAGCCAACAGAGACAATAGGAGACTTGTCAGTCTGTCTTGATGGCCTACAATTAGAGGCTGAAGGTGTTACTAATGGGGAAACTACAAGTTCAGAAAATGCTTCACAGAATGATGATGACTCCAGACCCAAGGATGAAACAAGAGTGAACACAAATGAATCAGGTGACACTGAAGATGCAGGGTCTGGTGAAAATAAGAGAGTCAATGGGAATAATTCTCCATCACTCTCAAATGGTGGTTTCAAACCTTCTAGACCTCCGAGACCTTCACGACCACCTCCACCTACCCCACGTAGACCAGCTTCTGTCAATGGTTCACCGTCTGCCACATCTGAAAGTGATGGATCTAGTACAGGTTCTCTGCCACCAACAAACACAAATACAAATACATCTGAAGGAACAACATCTGGATTAATAATCCCTCTTACTATATCGGGAGGCTCAGGCCCTAGGCCATTAAATCCTGTAACTCAAGCTCCCCTACCACCTGGGTGGGAACAGAGAGTGGACCAGCATGGGCGAGTTTATTATGTAGATCATGTTGAAAAAAGAACAACATGGGATAGACCTGAACCTCTACCTCCTGGTTGGGAACGGCGGGTTGACAACATGGGACGTATTTATTATGTTGACCATTTCACAAGAACAACAACATGGCAGAGGCCAACATTAGAATCTGTTCGGAACTATGAGCAGTGGCAGCTGCAACGTAGTCAACTGCAAGGAGCTATGCAGCAGTTTAACCAGAGATTCATTTATGGGAATCAAGATTTGTTTGCTGCATCACAAAATAAAGAATTTGATCCCCTTGGCCCTTTGCCACCTGGATGGGAGAAGAGAACTGATAGCAATGGCAGAGTGTATTTTGTCAATCACAACACTCGAATTACACAGTGGGAAGACCCCAGAAGTCAAGGTCAATTAAATGAAAAGCCCTTACCTGAAGGCTGGGAAATGAGATTCACAGTGGATGGAATTCCATATTTTGTGGATCACAATAGAAGAACAACCACCTATATAGATCCCCGCACAGGAAAATCTGCCCTGGACAATGGACCTCAGATAGCCTATGTTCGGGACTTCAAGGCAAAGGTTCAGTATTTCCGGTTCTGGTGTCAGCAATTGGCCATGCCACAGCACATAAAGATTACAGTAACAAGAAAAACATTATTTGAGGATTCCTTTCAGCAGATAATGAGCTTCAGTTCTCAAGATCTTCGAAGACGTTTGTGGGTGATTTTTCCAGGAGAAGAAGGTTTAGATTATGGAGGTGTAGCAAGAGAATGGTTCTTTCTTTTGTCACATGAAGTGTTGAACCCAATGTATTGCCTGTTTGAATATGCAGGGAAGGATAACTACTGCTTACAGATAAACCCTGCTTCTTACATCAATCCAGATCACCTGAAATATTTTCGGTTTATTGGCAGGTTTATCGCCATGGCTCTGTTCCATGGGAAATTCATAGACACAGGTTTTTCTTTACCGTTCTACAAACGTATCCTTAACAAACCAGTTGGACTTAAGGATTTAGAATCTATTGACCCAGAATTTTATAATTCTCTCATCTGGGTTAAAGAAAACAACATTGAGGAATGTGGTTTGGAAATGTACTTCTCTGTCGATAAAGAAATTCTAGGTGAAATTAAGAGTCATGATTTAAAACCAAATGGTGGCAATATTCTTGTAACAGAAGAAAATAAAGAAGAATACATCAGAATGGTAGCTGAGTGGAGGTTGTCTCGAGGTGTTGAAGAACAGACGCAAGCTTTCTTCGAAGGTTTTAATGAAATTCTTCCCCAGCAGTATTTGCAGTACTTTGATGCAAAGGAATTAGAGGTCCTTTTATGTGGCATGCAGGAGATTGATTTGAATGACTGGCAAAGACATGCCATCTACCGTCATTACACTAGGACAAGCAAACAAATCATGTGGTTTTGGCAGTTTGTTAAAGAAATTGATAATGAGAAGAGAATGAGACTTTTGCAGTTTGTTACTGGAACCTGCCGATTGCCAGTAGGAGGATTTGCTGACCTCATGGGGAGCAATGGACCACAGAAATTCTGCATTGAAAAAGTTGGGAAGGAAAATTGGTTACCCAGAAGCCATACCTGTTTTAACCGCCTGGACCTTCCACCTTACAAGAGCTATGAGCAACTGAAGGAAAAGCTGTTGTTTGCCATTGAAGAAACAGAAGGATTTGGACAAGAGTAA

Related Sequences

XP_004867974.1 Protein

Itch PREDICTED: E3 ubiquitin-protein ligase Itchy homolog [Heterocephalus glaber]

Length: 862 aa      View alignments
>XP_004867974.1
MSDSGSQLGSMGSLTMKSQLQITVLSAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAAVDIYETLKSNNMKLEEVVVSLQLIGDKEPTETIGDLSVCLDGLQLEAEGVTNGETTSSENASQNDDDSRPKDETRVNTNESGDTEDAGSGENKRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNTSEGTTSGLIIPLTISGGSGPRPLNPVTQAPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFAASQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSSQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE