Details from NCBI annotation

Gene Symbol Mthfr
Gene Name methylenetetrahydrofolate reductase (NAD(P)H), transcript variant X3
Entrez Gene ID 101719335

Database interlinks

Part of NW_004624818.1 (Scaffold)

For more information consult the page for NW_004624818.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

MTHFR ENSCPOG00000002899 (Guinea pig)

Gene Details

methylenetetrahydrofolate reductase (NAD(P)H)

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000002634, Guinea pig)

Protein Percentage 91.2%
CDS Percentage 91.87%
Ka/Ks Ratio 0.09611 (Ka = 0.0391, Ks = 0.407)

MTHFR ENSG00000177000 (Human)

Gene Details

methylenetetrahydrofolate reductase (NAD(P)H)

External Links

Gene Match (Ensembl Protein ID: ENSP00000365777, Human)

Protein Percentage 88.12%
CDS Percentage 86.88%
Ka/Ks Ratio 0.08326 (Ka = 0.0588, Ks = 0.7058)

Mthfr ENSMUSG00000029009 (Mouse)

Gene Details

5,10-methylenetetrahydrofolate reductase

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000069774, Mouse)

Protein Percentage 88.72%
CDS Percentage 86.91%
Ka/Ks Ratio 0.07245 (Ka = 0.0541, Ks = 0.7466)

Mthfr ENSRNOG00000008553 (Rat)

Gene Details

Methylenetetrahydrofolate reductase

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000011384, Rat)

Protein Percentage 87.94%
CDS Percentage 86.66%
Ka/Ks Ratio 0.07343 (Ka = 0.0584, Ks = 0.7951)

Genome Location

Sequence Coding sequence

Length: 1947 bp    Location: 1184706..1202679   Strand: +
>XM_004863566.1
ATGGTGAACGAGGCTCGAGGGAGTGGCGGTAGCAGCAGTGGCAGCGAGGGCTCTAAGGACAGTTCGAGGTGTTCCACCCCTGGCCTGGACCCCGAGCGTCACGAGAGACTCCGGGAGAAGATGAGGCGGAGGATGGAATCTGGGGACAAATGGTTCTCCCTGGAATTCTTCCCTCCCCGGACTTCGGAGGGAGCCGCCAACCTCATCTCCATGTTTGACCAGATGGCAGCAGGTGGCCCCCTCTTCATAGATGTGACCTGGCACCCAGCGGGGGACCCTGGCTCGGATAAGGAAACGTCCTCCATGATGATCGCCAGCACGGCTGTGAATTACTGTGGCCTGGAAACCATGCTGCACATGACGTGCTGCCAGCAGAGCCCGGAGGCGATCACAGGCCACCTGTACAAAGCCAAGCAGCTGGGCATCAAGAGCATCTTGGCGCTGCGGGGAGACCCCATAGGTGACCAGTGGGAAGCAGAAGAAGGAGGCTTTGACCATGCCACAGACCTAGTGAAGCACATCCGAAGCGAGTTTGGTGACTACTTTGACATCTGTGTGGCAGGTTACCCCAAAGGCCACCCCGAGGCAGGGAGCTTTGAGGAGGACCTGAGGCACCTGAAGGAAAAGGTGTCTGCAGGCGCCGACTTCATCATTAGCCAGCTCTTCTTTGAGGCCAACACCTTCTTCCACTTTGTGAAGGCCTGTGATGACATCGGCATCACCTGCCCCATCCTCCCCGGGATCTTCCCTATCCAGAGCTACTCCTCCCTCCGGCAGCTTGTGAAGCTGTCCAAGCTGGAGGTACCGCAGGAGATCAAGGATGTGATCGAGCCGATCAAAGACAATGACGCTGCCATCTGCAACTATGGCATCGAGCTGGCCGTGAGCCTGAGCCGGGAGCTTCTAGTCAGCGGCTTGGTGCCAGGCCTCCACTTCTACACCCTTAACCGCAAGATGGCCACCACCAGCGTGCTGAAGCGCCTGGGCATGTGGACTGAGGACCCCAGGCGTCCCCTCCCCTGGGCCGTCAGCGCACACCCCAAGCGCCGAGAGGAAGATGTGCGCCCCATCTTCTGGGCTTCCAGACCAAAGAGCTACATCTACCGCACCCAGGACTGGAATGAGTTTCCCAACGGCCGCTGGGGCAACTCCTCCTCGCCAGCCTTTGGGGAGCTGAAGAACTACTACCTCTTCTACCTGAAAAGCAAGTCGCCCCGGCAGGAGCTGCTGAAGATGTGGGGTGAGGAGCTCAGGAGCGAGGAGAGCGTCTTCGAAGTCTTCGCGCACTACATCTCAGGGGAGCCAAACCGGCACGGGTACAAGGTGACCTGCCTGCCCTGGAACGATGAGCCCCTGGCAGCCGAGACCAGCCTGATGAAGAAGCAGCTGCTGCGCGTGAACCGGCTGGGCATCCTTACCGTCAACTCCCAGCCCAACGTCAACGGGAGACCGTCGTCCGACCCCATTGTGGGCTGGGGCCCTAGCGGGGGCTACGTCTTCCAGAAGGCCTACCTGGAGTTCTTCACCTCCCGAGAGACAGTGGAGGCACTCCTGCAGGTGATGAAGAAGTACGAGCTTCGGGTCAATTACCACATCGTGGATGTGAAGGGTGAGAACATCACCAATGCCCCCGAGCTGCAGCCCAATGCCGTCACGTGGGGCATCTTCCCGGGACGAGAGATCATCCAGCCCACGGTGGTGGATCCTGTCAGCTTCATGTTCTGGAAGGATGAGGCCTTCGCCCTGTGGATCGAGCAGTGGGGCAAGCTGTACGATGAGGAGTCCCCATCCCGCATGATCATCCAGTACATCCACGACAACTACTTCCTGGTCAACCTGGTGGACAATGAGTTCCCGCAGGACAGCTGCCTGTGGCAGGTGGTGGAGGACGCATTCGAGCTGCTCAACAGGCCTGCTGGGCTCAAGGGGGAGGCGGAGGCGCAGTGA

Related Sequences

XP_004863623.1 Protein

Mthfr PREDICTED: methylenetetrahydrofolate reductase isoform X3 [Heterocephalus glaber]

Length: 648 aa      View alignments
>XP_004863623.1
MVNEARGSGGSSSGSEGSKDSSRCSTPGLDPERHERLREKMRRRMESGDKWFSLEFFPPRTSEGAANLISMFDQMAAGGPLFIDVTWHPAGDPGSDKETSSMMIASTAVNYCGLETMLHMTCCQQSPEAITGHLYKAKQLGIKSILALRGDPIGDQWEAEEGGFDHATDLVKHIRSEFGDYFDICVAGYPKGHPEAGSFEEDLRHLKEKVSAGADFIISQLFFEANTFFHFVKACDDIGITCPILPGIFPIQSYSSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAICNYGIELAVSLSRELLVSGLVPGLHFYTLNRKMATTSVLKRLGMWTEDPRRPLPWAVSAHPKRREEDVRPIFWASRPKSYIYRTQDWNEFPNGRWGNSSSPAFGELKNYYLFYLKSKSPRQELLKMWGEELRSEESVFEVFAHYISGEPNRHGYKVTCLPWNDEPLAAETSLMKKQLLRVNRLGILTVNSQPNVNGRPSSDPIVGWGPSGGYVFQKAYLEFFTSRETVEALLQVMKKYELRVNYHIVDVKGENITNAPELQPNAVTWGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYDEESPSRMIIQYIHDNYFLVNLVDNEFPQDSCLWQVVEDAFELLNRPAGLKGEAEAQ