Details from NCBI annotation

Gene Symbol Scn8a
Gene Name sodium channel, voltage gated, type VIII, alpha subunit, transcript variant X2
Entrez Gene ID 101711868

Database interlinks

Part of NW_004624816.1 (Scaffold)

For more information consult the page for NW_004624816.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

SCN8A ENSCPOG00000015651 (Guinea pig)

Gene Details

Uncharacterized protein

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000014115, Guinea pig)

Protein Percentage 94.59%
CDS Percentage 91.94%
Ka/Ks Ratio 0.14638 (Ka = 0.0386, Ks = 0.2634)

SCN8A ENSG00000196876 (Human)

Gene Details

sodium channel, voltage gated, type VIII, alpha subunit

External Links

Gene Match (Ensembl Protein ID: ENSP00000346534, Human)

Protein Percentage 99.04%
CDS Percentage 94.85%
Ka/Ks Ratio 0.02001 (Ka = 0.0044, Ks = 0.2204)

Scn8a ENSMUSG00000023033 (Mouse)

Gene Details

sodium channel, voltage-gated, type VIII, alpha

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000080842, Mouse)

Protein Percentage 98.33%
CDS Percentage 89.64%
Ka/Ks Ratio 0.01379 (Ka = 0.0083, Ks = 0.6018)

Scn8a ENSRNOG00000005309 (Rat)

Gene Details

sodium channel protein type 8 subunit alpha

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000008160, Rat)

Protein Percentage 98.05%
CDS Percentage 89.65%
Ka/Ks Ratio 0.01667 (Ka = 0.01, Ks = 0.6022)

Genome Location

Sequence Coding sequence

Length: 5943 bp    Location: 631840..499170   Strand: -
>XM_004862929.1
ATGGCAGCGCGGCTGCTTGCACCACCAGGCCCTGATAGTTTCAAGCCGTTTACCCCTGAGTCACTGGCAAACATTGAGAGGCGCATTGCTGAGAGCAAGCTCAAGAAACCACCAAAGGCCGATGGCAGCCATCGGGAAGATGATGAGGACAGCAAGCCCAAACCAAACAGTGACCTGGAAGCAGGGAAGAGTTTGCCTTTCATCTACGGGGATATCCCCCAAGGCCTGGTTGCAGTTCCCCTGGAGGACTTTGACCCATACTATTTGACGCAGAAAACCTTTGTAGTATTAAACAGAGGGAAAACTCTCTTCAGATTTAGTGCCACGCCTGCCTTGTACATTTTAAGTCCTTTTAACCTGATAAGAAGAATAGCTATTAAAATTTTAATACATTCAGTATTTAGCATGATCATTATGTGCACTATTTTGACCAACTGTGTATTCATGACTTTTAGTAACCCTCCTGAGTGGTCGAAGAATGTGGAGTACACATTCACAGGGATTTATACATTCGAATCAGTAGTGAAAATCCTTGCAAGAGGTTTCTGCATAGATGGCTTTACCTTTTTACGGGATCCATGGAACTGGTTAGATTTCAGTGTCATCATGATGGCGTATATAACAGAGTTTGTAAACCTAGGCAATGTTTCAGCTCTGCGCACTTTCAGGGTACTGAGGGCTTTGAAAACTATTTCGGTAATCCCAGGCCTGAAGACAATTGTGGGCGCCCTCATTCAGTCTGTGAAGAAGCTGTCAGATGTGATGATCCTGACAGTATTCTGCCTGAGTGTTTTCGCCCTGATTGGACTGCAGCTGTTCATGGGGAACCTGCGAAACAAGTGTGTTGTGTGGCCCATAAACTTCAACGAGAGCTATCTTGAAAACGGCACCAGAGGCTTTGACTGGGAAGAGTATATCAACAATAAAACAAATTTTTACACAGTTTCTGGCATGCTGGAACCTTTACTCTGTGGGAACAGTTCTGATGCTGGGCAATGCCCAGAGGGATACCAGTGTATGAAAGCAGGAAGGAACCCCAACTATGGTTACACAAGTTTTGACACTTTTAGCTGGGCCTTCTTGGCTTTATTTCGCCTTATGACCCAGGACTACTGGGAAAACTTGTATCAACTGACCTTACGAGCAGCTGGAAAAACATACATGATCTTCTTCGTCTTGGTAATTTTTGTGGGTTCTTTCTATCTGGTGAACTTAATCTTGGCTGTGGTGGCCATGGCTTATGAAGAGCAGAATCAGGCAACACTGGAGGAAGCAGAGCAAAAAGAGGCTGAATTCAAAGCAATGTTAGAGCAACTTAAGAAACAACAGGAAGAGGCACAGGCTGCCGCAATGGCCACTTCGGCCGGCACTGTCTCAGAAGATGCCATCGAGGAAGAAGGTGAAGAAGGGGTTGGCTCTCCTCGGAGCTCATCTGAAATTTCTAAACTCAGTTCAAAAAGTGCCAAAGAAAGACGTAACAGGAGAAAGAAGAGGAAACAGAAGGAACTCTCTGAAGGAGAGGAGAAAGGAGATCCTGAGAAGGTGTTTAAGTCAGAGTCAGAAGATGGTATGAGGAGGAAGGCCTTTCGGCTACCAGACAACAGAATAGGGAGGAAATTTTCCATCATGAATCAGTCACTGCTCAGCATCCCAGGCTCCCCTTTCCTCTCCCGCCACAACAGCAAGAGCAGCATCTTCAGCTTCCGGGGCCCTGGGCGTTTTCGAGATCCTGGCTCTGAGAATGAGTTCGCGGACGACGAGCACAGCACGGTGGAGGAGAGCGAGGGCCGCCGGGACTCGCTGTTCATCCCGATCCGGGCTCGAGAGCGCCGCAGCAGCTACAGCGGCTACAGCGGCTACAGCCAGGGCAGCCGCTCCTCGCGCATCTTCCCCAGCCTGCGGCGAAGCGTGAAGCGCAACAGCACGGTGGACTGCAACGGCGTGGTGTCCCTTATCGGAGGGCCTGGCTCCCACATCGGTGGGCGGCTCCTGCCAGAGGGAACAACAGAGGTGGAAATTAAGAAGAAAGGCCCTGGATCTCTTTTAGTATCCATGGACCAACTGGCCTCCTATGGACGAAAAGACAGAATCAACAGTATAATGAGTGTTGTTACAAATACACTAGTAGAAGAGCTGGAAGAGTCTCAGAGAAAGTGCCCACCATGCTGGTATAAATTTGCCAACACTTTCCTCATCTGGGAGTGTCACCCCTATTGGATAAAACTGAAAGAGATTGTAAACTTGATTGTTATGGACCCTTTTGTGGACTTGGCCATCACCATCTGCATTGTACTGAACACACTGTTTATGGCAATGGAGCACCATCCTATGACGCCACAGTTTGAACATGTCTTGACTGTAGGAAATCTGGTTTTCACTGGAATTTTCACGGCAGAAATGTTCCTGAAGCTAATAGCCATGGATCCTTACTATTATTTCCAAGAAGGTTGGAATATTTTTGACGGATTTATTGTCTCCCTCAGTTTAATGGAACTGAGTCTAGCAGATGTGGAGGGGCTTTCAGTGCTGCGATCTTTCCGATTGCTCCGAGTCTTCAAATTGGCCAAATCCTGGCCCACCCTGAATATGCTGATCAAGATTATTGGAAATTCAGTGGGTGCCCTGGGTAACCTGACCCTGGTGCTGGCCATTATTGTCTTCATCTTTGCCGTGGTGGGAATGCAGCTCTTTGGGAAAAGCTACAAAGAGTGTGTCTGCAAGATCAACCAGAACTGTGAACTTCCTCGCTGGCACATGCATGACTTTTTCCATTCCTTCCTCATTGTCTTTCGAGTATTGTGCGGGGAGTGGATTGAGACCATGTGGGACTGCATGGAGGTGGCGGGCCAGGCCATGTGCCTCATTGTCTTTATGATGGTCATGGTCATTGGCAACTTGGTGGTGCTGAATCTGTTTCTGGCCTTGCTTCTGAGCTCCTTCAGTGCAGACAACCTGGCAGCCACTGACGATGATGGCGAAATGAACAACCTACAGATCTCAGTCATCCGCATCAAGAAAGGTGTCGCTTGGACCAAACTAAAAGTACATGCCTTTATGCAGGCTCACTTTAAGCAGCATGAGGGGGATGAAGTGAAACCCCTGGATGAGCTGTATGAAAAGAAGGCCAACTGTATCGCCAACCACACTGGTGCAGACATCCATAGGAATGGTGACTTTCAGAAGAATGGCAATGGCACAACCAGTGGCATTGGCAGCAGTGTGGAGAAGTACATCATTGATGAAGACCATATGTCCTTCATCAACAATCCCAACTTGACTGTGCGGGTGCCCATTGCTGTAGGCGAGTCTGATTTTGAGAACCTCAACACAGAAGATGTTAGCAGCGAGTCGGATCCTGAAGGCAGCAAAGATAAATTGGATGACACTAGCTCCTCCGAAGGAAGCACCATTGATATCAAGCCAGAAGTAGAAGAAGTCCCTGTGGAACAGCCCGAGGAGTACTTGGATCCAGATGCCTGCTTCACAGAAGGTTGTGTCCAGCGGTTCAAGTGCTGCCAGGTCAACATTGAAGAAGGGCTGGGCAAGTCTTGGTGGATCCTGCGGAAAACCTGCTTTCTCATCGTAGAGCACAATTGGTTTGAGACCTTCATCATCTTCATGATTCTGCTCAGCAGTGGTGCCCTGGCCTTTGAGGACATCTACATTGAACAGAGGAAGACTATTCGCACTATCCTGGAATACGCTGACAAGGTCTTCACCTACATCTTCATCCTGGAGATGTTGCTCAAGTGGACGGCCTATGGGTTTGTCAAGTTCTTCACCAATGCCTGGTGCTGGCTGGACTTCCTCATCGTGGCTGTCTCTTTAGTCAGCCTTATAGCTAATGCCCTGGGCTACTCGGAACTAGGTGCCATAAAGTCCCTTAGGACCCTAAGAGCTTTGAGACCCTTAAGAGCCTTATCACGATTTGAAGGGATGAGGGTGGTGGTGAATGCCTTGGTGGGTGCCATCCCCTCCATCATGAATGTGCTGCTGGTGTGTCTCATCTTCTGGCTGATTTTCAGCATCATGGGTGTTAACCTGTTTGCCGGAAAGTACCACTTCTGCTTTAATGAGACTTCTGAAATCCGATTCGAAATTGAACATGTTAACAATAAAACTGAGTGTGAAAAGCTGATGGAGGGGAACAACACAGAGATCAGATGGAAGAACGTGAAGATCAACTTCGACAACGTTGGGGCAGGGTATCTGGCCCTTCTTCAAGTAGCAACCTTCAAAGGCTGGATGGACATCATGTATGCAGCCGTAGATTCCCGAAAGCCTGATGAGCAGCCTAAGTATGAGGACAACATCTACATGTATATCTACTTTGTCATCTTCATCATCTTCGGCTCCTTCTTCACCCTGAACCTCTTCATTGGTGTCATCATTGATAACTTCAATCAACAAAAGAAAAAGTTTGGAGGTCAGGACATCTTCATGACTGAGGAACAGAAGAAGTACTACAATGCCATGAAAAAGCTGGGCTCAAAGAAACCACAGAAACCGATTCCCCGTCCTTTGAACAAAATCCAAGGTATCATCTTTGATTTTGTCACTCAACAAGCCTTTGACATTGTTATCATGATGCTCATCTGCCTTAACATGGTGACAATGATGGTAGAGACAGATACTCAGAGCAAGCAGATGGAGAACATTCTCTACTGGATTAATCTGGTCTTTGTCATCTTCTTCACCTGTGAGTGTGTGCTCAAAATGTTTGCCTTGAGGCACTACTACTTCACCATTGGCTGGAACATCTTCGACTTCGTGGTGGTCATCCTCTCCATTGTAGGGATGTTTCTGGCTGATATCATTGAGAAATACTTTGTTTCCCCAACCCTATTCCGAGTCATCCGATTGGCCCGTATTGGGCGCATCTTGCGTCTAATCAAAGGTGCCAAAGGGATTCGTACCCTGCTCTTTGCCTTAATGATGTCCTTGCCTGCCCTGTTCAACATTGGCCTTCTGCTCTTCCTGGTCATGTTCATCTTCTCCATCTTTGGGATGTCCAATTTTGCATACGTGAAGCATGAGGCTGGCATTGATGACATGTTCAACTTTGAGACATTTGGCAACAGCATGATCTGCCTGTTTCAGATCACAACCTCGGCTGGTTGGGATGGCCTGCTGCTCCCCATCCTTAACCGCCCCCCTGACTGCAGCCTGGACAAGGAACACCCAGGGAGTGGCTTTAAGGGAGACTGCGGGAACCCCTCTGTGGGCATCTTCTTCTTTGTAAGCTACATCATCATCTCCTTCTTGATTGTGGTGAACATGTACATTGCCATCATCTTGGAGAACTTCAGTGTAGCTACAGAAGAAAGTGCAGACCCTCTGAGTGAGGATGACTTTGAGACCTTCTATGAGATCTGGGAGAAGTTTGACCCCGACGCCACCCAGTTCATTGAGTACTGTAAGCTGGCAGACTTCGCAGATGCCTTGGAGCATCCTCTCCGAGTCCCCAAGCCCAACACCATTGAGCTCATCGCCATGGATCTTCCAATGGTGAGTGGGGATCGCATTCACTGCTTGGACATCCTTTTTGCCTTCACCAAGCGGGTCTTGGGAGACAGCGGAGAGTTGGACATCCTGCGACAGCAGATGGAGGAGCGGTTCGTGGCATCCAATCCTTCCAAAGTGTCTTACGAGCCAATCACAACCACCCTGCGACGCAAGCAGGAGGAGGTGTCTGCAGTGGTCCTGCAGCGAGCCTACCGGGGACATTTGGCAAGGCGAGGCTTCAGCTGCAAAAAGATGACTTCCAATAAGCTAGAGAATGGAGGCACCCACCAGGAGAAAAAGGAGAGCACCCCATCCACAGCCTCCCTCCCATCCTATGACAGTGTAACTAAACCTGACAAGGAGAAACAGCAGCGGGCAGAGGAAGGAAGAAAGGAAAGAGCCAAAAGACAAAAAGAGGTCAGAGAATCCAAATGTTAG

Related Sequences

XP_004862986.1 Protein

Scn8a PREDICTED: sodium channel protein type 8 subunit alpha isoform X2 [Heterocephalus glaber]

Length: 1980 aa      View alignments
>XP_004862986.1
MAARLLAPPGPDSFKPFTPESLANIERRIAESKLKKPPKADGSHREDDEDSKPKPNSDLEAGKSLPFIYGDIPQGLVAVPLEDFDPYYLTQKTFVVLNRGKTLFRFSATPALYILSPFNLIRRIAIKILIHSVFSMIIMCTILTNCVFMTFSNPPEWSKNVEYTFTGIYTFESVVKILARGFCIDGFTFLRDPWNWLDFSVIMMAYITEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVVWPINFNESYLENGTRGFDWEEYINNKTNFYTVSGMLEPLLCGNSSDAGQCPEGYQCMKAGRNPNYGYTSFDTFSWAFLALFRLMTQDYWENLYQLTLRAAGKTYMIFFVLVIFVGSFYLVNLILAVVAMAYEEQNQATLEEAEQKEAEFKAMLEQLKKQQEEAQAAAMATSAGTVSEDAIEEEGEEGVGSPRSSSEISKLSSKSAKERRNRRKKRKQKELSEGEEKGDPEKVFKSESEDGMRRKAFRLPDNRIGRKFSIMNQSLLSIPGSPFLSRHNSKSSIFSFRGPGRFRDPGSENEFADDEHSTVEESEGRRDSLFIPIRARERRSSYSGYSGYSQGSRSSRIFPSLRRSVKRNSTVDCNGVVSLIGGPGSHIGGRLLPEGTTEVEIKKKGPGSLLVSMDQLASYGRKDRINSIMSVVTNTLVEELEESQRKCPPCWYKFANTFLIWECHPYWIKLKEIVNLIVMDPFVDLAITICIVLNTLFMAMEHHPMTPQFEHVLTVGNLVFTGIFTAEMFLKLIAMDPYYYFQEGWNIFDGFIVSLSLMELSLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINQNCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDGEMNNLQISVIRIKKGVAWTKLKVHAFMQAHFKQHEGDEVKPLDELYEKKANCIANHTGADIHRNGDFQKNGNGTTSGIGSSVEKYIIDEDHMSFINNPNLTVRVPIAVGESDFENLNTEDVSSESDPEGSKDKLDDTSSSEGSTIDIKPEVEEVPVEQPEEYLDPDACFTEGCVQRFKCCQVNIEEGLGKSWWILRKTCFLIVEHNWFETFIIFMILLSSGALAFEDIYIEQRKTIRTILEYADKVFTYIFILEMLLKWTAYGFVKFFTNAWCWLDFLIVAVSLVSLIANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKYHFCFNETSEIRFEIEHVNNKTECEKLMEGNNTEIRWKNVKINFDNVGAGYLALLQVATFKGWMDIMYAAVDSRKPDEQPKYEDNIYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKIQGIIFDFVTQQAFDIVIMMLICLNMVTMMVETDTQSKQMENILYWINLVFVIFFTCECVLKMFALRHYYFTIGWNIFDFVVVILSIVGMFLADIIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIFSIFGMSNFAYVKHEAGIDDMFNFETFGNSMICLFQITTSAGWDGLLLPILNRPPDCSLDKEHPGSGFKGDCGNPSVGIFFFVSYIIISFLIVVNMYIAIILENFSVATEESADPLSEDDFETFYEIWEKFDPDATQFIEYCKLADFADALEHPLRVPKPNTIELIAMDLPMVSGDRIHCLDILFAFTKRVLGDSGELDILRQQMEERFVASNPSKVSYEPITTTLRRKQEEVSAVVLQRAYRGHLARRGFSCKKMTSNKLENGGTHQEKKESTPSTASLPSYDSVTKPDKEKQQRAEEGRKERAKRQKEVRESKC