Details from NCBI annotation

Gene Symbol Pak4
Gene Name p21 protein (Cdc42/Rac)-activated kinase 4, transcript variant X1
Entrez Gene ID 101720492

Database interlinks

Part of NW_004624794.1 (Scaffold)

For more information consult the page for NW_004624794.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

PAK4 ENSCPOG00000027079 (Guinea pig)

Gene Details

p21 protein (Cdc42/Rac)-activated kinase 4

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000018837, Guinea pig)

Protein Percentage 96.61%
CDS Percentage 93.11%
Ka/Ks Ratio 0.05217 (Ka = 0.016, Ks = 0.3076)

PAK4 ENSG00000130669 (Human)

Gene Details

p21 protein (Cdc42/Rac)-activated kinase 4

External Links

Gene Match (Ensembl Protein ID: ENSP00000469413, Human)

Protein Percentage 94.38%
CDS Percentage 90.74%
Ka/Ks Ratio 0.05272 (Ka = 0.0269, Ks = 0.5108)

Pak4 ENSMUSG00000030602 (Mouse)

Gene Details

p21 protein (Cdc42/Rac)-activated kinase 4

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000103918, Mouse)

Protein Percentage 92.71%
CDS Percentage 87.18%
Ka/Ks Ratio 0.05303 (Ka = 0.0356, Ks = 0.6705)

Pak4 ENSRNOG00000019883 (Rat)

Gene Details

p21 protein (Cdc42/Rac)-activated kinase 4 (Pak4), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000026966, Rat)

Protein Percentage 93.73%
CDS Percentage 87.63%
Ka/Ks Ratio 0.04959 (Ka = 0.0322, Ks = 0.6489)

Genome Location

Sequence Coding sequence

Length: 1773 bp    Location: 12457108..12498837   Strand: +
>XM_004859093.1
ATGTTTGGGAAGAGGAAGAAGCGAGTGGAGATTTCAGCGCCCTCCAACTTTGAGCACCGCGTACACACAGGCTTCGACCAGCACGAACAGAAATTCACAGGGCTGCCACGTCAATGGCAGAGCCTGATTGAGGAGTCGGCTCGCCGGCCCAAGCCCCTCGTGGACCCCGCCTGCATCACCTCCATCCAGCCTGGGGCCCCCAAGACCATCGTGCGGGGCAGCAAAGGTGCCAAGGATGGGGCCCTCACGCTGCTGCTGGATGAATTTGAGAACATGTCGGTGACACGCTCCAACTCCCTGCGGAGAGACAGCCCACCACCCCCCGCCCGTGCCCGCCAGGAGAACGGGGTGCCAGAGGAGCAGGCTGCTGCGGCCAGAGTGGGCCCGGACAAGGCCGGCGGCCGAGGCCGGGTCACCGCTCACAGTGAGGCTGGCAGTGGTGACAGGCGGCGGGTGGGCCCAGAGAAGAGGCCCAAGTCCTCCAGGGAGGGCCCAGGAGGCCCCCTGGAGTCCTCCAGAGACAAGCGCCCCCAATCTGGGCCTGATGTCAGCACCCCCCAACCTGCCGGTCTGGCCAGAGAGGCAAAACTGGTGGCCAACCGGCCCTTTAACACGTACCCACGGGCCGATACAGACCACCCGTCCCGGGGCACCCAGGGGGAGCCTCCCAGCATGGCCCCCAATGGGCCATCCGTGGGGGGCCTGGCCGCCCCACAGTCTTCTTCCTCCCGGCCTCCCGCCCGAGGCCGAGGTGCCCCCAGCCCTGGAGTGCTGGGCCCCCATGCCTCTGAGCCCCAGCTGGCCCCTCCAGCCCGCACCCTTGCTGCCCCTGCTGCGCCCCCAGCCCCTGGTCCCCCTGGTCCCCGCTCACCACAGCGGGAGCCCCAGCGAGTGTCCCACGAGCAGTTCCGGGCTGCCCTGCAGCTGGTGGTGGACCCAGGGGACCCCCGCTCCTACCTGGACAACTTCATCAAGATCGGCGAGGGCTCCACAGGCATCGTGTGCATTGCCACTGTGCGCAGCTCGGGCAAGCTGGTGGCCGTCAAGAAGATGGACCTGCGCAAGCAGCAGCGGCGCGAGCTGCTCTTCAACGAGGTGGTGATCATGCGGGACTACCAGCACGAGAATGTGGTGGAGATGTACAACAGCTACCTGGTGGGGGATGAGCTCTGGGTGGTGATGGAGTTTCTGGAGGGTGGCGCCCTCACTGACATCGTCACCCACACCAGGATGAACGAGGAGCAGATCGCTGCCGTGTGCCTGGCTGTGCTGCAGGCCCTGTCTGTGCTCCACGCCCAAGGCGTCATCCACCGGGACATCAAGAGTGACTCCATCCTGCTGACCCACGACGGCAGGGTGAAGCTGTCCGACTTCGGGTTTTGTGCCCAGGTGAGCAAGGAAGTGCCACGGAGGAAGTCACTGGTGGGCACGCCCTACTGGATGGCCCCAGAGCTCATCTCCCGTCTTCCCTATGGGCCAGAGGTGGACATCTGGTCGCTGGGGGTAATGGTGATCGAGATGGTGGATGGGGAGCCTCCCTACTTCAATGAGCCACCCCTCAAAGCCATGAAGATGATTCGGGACAACCTCCCACCACGACTGAAGAACCTACACAAAGTGTCACCATCTCTGAAGGGCTTCCTGGACCGCCTGCTGGTTCGAGACCCGGGCCAGCGTGCCACAGCGGCCGAGCTGCTGAAGCACCCGTTCCTGGCCAAGGCGGGGCCGCCCTCCAGCATCGTGCCCCTCATGCGCCAGAACCGCACCAGATGA

Related Sequences

XP_004859150.1 Protein

Pak4 PREDICTED: serine/threonine-protein kinase PAK 4 isoform X1 [Heterocephalus glaber]

Length: 590 aa      View alignments
>XP_004859150.1
MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACITSIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARARQENGVPEEQAAAARVGPDKAGGRGRVTAHSEAGSGDRRRVGPEKRPKSSREGPGGPLESSRDKRPQSGPDVSTPQPAGLAREAKLVANRPFNTYPRADTDHPSRGTQGEPPSMAPNGPSVGGLAAPQSSSSRPPARGRGAPSPGVLGPHASEPQLAPPARTLAAPAAPPAPGPPGPRSPQREPQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPGQRATAAELLKHPFLAKAGPPSSIVPLMRQNRTR