Details from NCBI annotation

Gene Symbol Ncstn
Gene Name nicastrin
Entrez Gene ID 101718052

Database interlinks

Part of NW_004624794.1 (Scaffold)

For more information consult the page for NW_004624794.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

NCSTN ENSCPOG00000014923 (Guinea pig)

Gene Details

nicastrin

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000013448, Guinea pig)

Protein Percentage 95.49%
CDS Percentage 93.7%
Ka/Ks Ratio 0.12566 (Ka = 0.0235, Ks = 0.1873)

NCSTN ENSG00000162736 (Human)

Gene Details

nicastrin

External Links

Gene Match (Ensembl Protein ID: ENSP00000294785, Human)

Protein Percentage 92.38%
CDS Percentage 90.55%
Ka/Ks Ratio 0.14052 (Ka = 0.0408, Ks = 0.2906)

Ncstn ENSMUSG00000003458 (Mouse)

Gene Details

nicastrin

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000003550, Mouse)

Protein Percentage 89.12%
CDS Percentage 87.29%
Ka/Ks Ratio 0.1361 (Ka = 0.0588, Ks = 0.4322)

Ncstn ENSRNOG00000005355 (Rat)

Gene Details

nicastrin (Ncstn), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000008150, Rat)

Protein Percentage 89.55%
CDS Percentage 86.96%
Ka/Ks Ratio 0.12925 (Ka = 0.0584, Ks = 0.452)

Genome Location

Sequence Coding sequence

Length: 2130 bp    Location: 923470..908227   Strand: -
>XM_004858716.1
ATGGCCACGGCCGGGGGCAGCTCTGAGGCTGACCCGGGAAGTCGGGGTCTTCTTCGCCTTCTGTCGTTCTGCGTTCTACTGGCAGGTTTGTGCAAGGGAAACTCTGTGGAGAGAAAGATCTACATTCCTTTAAATAAAACAGCTCCCTGTGTTCGTCTGCTCAATGCGACCCATCAGATTGGCTGCCAATCTTCAATTAATGGGGACACAGGGGTTATCCATGTAGTGGAGAAAGAAGAGGACCTGCGGTGGGTGTTGACAGATGGCCCCAACCCTCCTTACATGGTTCTGCTGGAAGGCAAACTGTTTACCAGGCATATAATGGAGAAGCTGAAGGGGAAAAACAGTCGGATTGCTGGGCTTGCAGTGACCTTGGCCAAGCCCAGTCCCACCCCTGGGTTCTCTCCTAGTGTGCAGTGCCCAAATGATGGGTTTGGTGTTTACTCCAACTCCTATGGGTCAGAGTTTGCCCACTGCAAAGAAAAGCCATGGAATCCTCTGGGCAGTGGCTTGGCTTATGAAGATTTTAGTTTCCCCATCTTTCTTCTTGAAGATGAAAATGAAACCAAGGTCATCAAGCAGTGCTATCAAGATCACAACCTGAGTCAGAATGGCTCAGCACCAGCCTTTCCACTGTGTGCCATGCAGCTGTTCTCACACATGCATGCCGTCATCAGCACTGCCACCTGCATGCGGCGCAGCTTCATCCAGAGCACCTTCAGCATCAACCCAGAAATCGTCTGTGACCCCCTGTCTGACTACAATGTATGGAGCATGCTCAAGCCTATAAATACATCTGGGACATTGGAGCCTGATGAGAGGGTAGTGGTTGCTGCTACCCGGCTGGACAGTCGTTCCTTTTTCTGGAATGTGGCCCCAGGGGCTGAAAGTGCAGTTGCCTCCTTCGTCACCCAGCTGGCTGCAGCTGAAGCCTTGCAAAAGGCACCTGATGTGACCACCCTGCCCCGCAATGTCATGTTTGTCTTCTTCCAAGGGGAAACTTTTGACTACATTGGCAGCTCAAGAATGGTCTACGATATGGAGAAGGGCAAGTTTCCTGTGCGGTTAGAGAACATAGACTCATTTGTGGAGCTGGGACAGGTGGCCTTAAGAACGTCTCTAGAGCTCTGGATGCACACAGATCCCATGTCTCAGAAAAATGAGTCTGTGCGGAACCAGGTAGAGGACCTTCTGGCCACGCTGGAGAGGAGTGGTGCTGATGTCCCTGATGTCATCCTCAGAAGAATTAATCAGTCCCATGCCCTCCCACCATCTTCTCTGCAGCGATTTCTTCGAGCTCAAAACATCTCTGGTGTCGTTCTGGCTGACCATAATGATTCCTTCCATAACCTCTATTACCAGAGCATTTACGACACTGCTGAGAACATTAATGTGAGCTATCCTGAGTGGCTGAGCCCTGAAGAGGACCTGAACTTTGTGACAGACACTGCCAAGGCCCTGGCGAATGTGGCCACAGTGCTGGGACGTGCACTGTATGTGCTTGCAGGAGGAAGCAACTTCAGCAACACAGTTGAGGCCGATCCCCAGACGGTCACCCGCCTGCTCTATGGATTCCTGATTCAAGCCAACAACTCGTGGTTCCAGTCTATCCTTAGACAGGACCTAAGGTCCTACTTGGGAGACGGGCCTCTTCAGCATTACATCGCTGTCTCCAGCCCCACCAACACCACTTACGTTGTGCAGTATGCCTTGGCAAATTTGACTGGCAAGGTGATCGACCTCACTCGAGAGCAGTGCCAGGATCCAAGTAAAGTTCCAAACGAAAACAAGGATCTGTATGAGTACTCATGGGTTCAGGGCCCTCTGAGTTCCAACGAGACAGACCGGCTGCCCCGGTGCGTGCGTTCCACAGCACGACTGGCCAGGGCCTTGTCACCTGCCTTCGAACTGAGTCAGTGGAGTTCCACTGAATACTCTACGTGGACTGAGAGCCGCTGGAAAGACATCCGGGCTCGGATATTCCTGATCGCCAGCAAAGAGCTTGAGTTTATCACCCTGATGGTGGGCTTTGGCATCCTCGTCTTCTCTCTCATCGTCACCTACTGCATCAATGCCAAAGCCGATGTCCTTTTCATTGCTCCCCGAGAGCCAGGAGCCGTGTCTTACTAG

Related Sequences

XP_004858773.1 Protein

Ncstn PREDICTED: nicastrin [Heterocephalus glaber]

Length: 709 aa      View alignments
>XP_004858773.1
MATAGGSSEADPGSRGLLRLLSFCVLLAGLCKGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSINGDTGVIHVVEKEEDLRWVLTDGPNPPYMVLLEGKLFTRHIMEKLKGKNSRIAGLAVTLAKPSPTPGFSPSVQCPNDGFGVYSNSYGSEFAHCKEKPWNPLGSGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPAFPLCAMQLFSHMHAVISTATCMRRSFIQSTFSINPEIVCDPLSDYNVWSMLKPINTSGTLEPDERVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVRLENIDSFVELGQVALRTSLELWMHTDPMSQKNESVRNQVEDLLATLERSGADVPDVILRRINQSHALPPSSLQRFLRAQNISGVVLADHNDSFHNLYYQSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALANVATVLGRALYVLAGGSNFSNTVEADPQTVTRLLYGFLIQANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGKVIDLTREQCQDPSKVPNENKDLYEYSWVQGPLSSNETDRLPRCVRSTARLARALSPAFELSQWSSTEYSTWTESRWKDIRARIFLIASKELEFITLMVGFGILVFSLIVTYCINAKADVLFIAPREPGAVSY