Sequence details NCBI ID: XM_004858557.1 (Coding sequence)   Best Hit

Details from NCBI annotation

Gene Symbol Irs2
Gene Name insulin receptor substrate 2
Entrez Gene ID 101719081

This gene is present in the GenAge database and has been identified as potentially important to ageing in humans.

Database interlinks

Part of NW_004624793.1 (Scaffold)

For more information consult the page for NW_004624793.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

IRS2 ENSG00000185950 (Human)

Gene Details

insulin receptor substrate 2

External Links

Gene Match (Ensembl Protein ID: ENSP00000365016, Human)

Protein Percentage 84.16%
CDS Percentage 84.29%
Ka/Ks Ratio 0.0738 (Ka = 0.0793, Ks = 1.0745)

Irs2 ENSMUSG00000038894 (Mouse)

Gene Details

insulin receptor substrate 2

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000038514, Mouse)

Protein Percentage 83.42%
CDS Percentage 80.69%
Ka/Ks Ratio 0.07714 (Ka = 0.0909, Ks = 1.1778)

Irs2 ENSRNOG00000023509 (Rat)

Gene Details

insulin receptor substrate 2 (Irs2), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000036862, Rat)

Protein Percentage 83.24%
CDS Percentage 80.7%
Ka/Ks Ratio 0.07588 (Ka = 0.0906, Ks = 1.1944)

Genome Location

Sequence Coding sequence

Length: 3927 bp    Location: 2615144..2636839   Strand: +
Raw sequence   
>XM_004858557.1
ATGGCGAGCCCGCCGCGGCAGGGAGCCCCTGGGCCAGCGGGCGGTGACGGCCCCAACCTGAATAACAACAACAACAACAACAACAACAACCACGGCGTGCGCAAGTGCGGCTACCTGCGCAAGCAGAAGCACGGCCACAAGCGCTTCTTCGTGCTGCGCGGGCCCGGCGCGGGCGGGGACGACGGGGGCGCGGGCGGGGGGCCGGCGGCGCCGCAGCCCCCGCGGCTCGAGTACTACGAGAGCGAGAAGAAGTGGCGGAGCAAGGCGGGCGCGCCGAAGCGGGTGATCGCGCTCGACTGCTGCCTGAATGTCAACAAGCGCGCCGACGCCAAGCACAAGTACCTGATCGCCCTCTACACCAAGGACGAGTACTTCGCTGTGGCGGCCGAGAACGAGCAGGAGCAGGAGGGCTGGTACCGCGCGCTCGCCGACCTGCTCAGCGAGGGCCGCGCGGCCGCCGCCGGCGACGCGCCCCCTGTGGCCACGGCCCCCGCCGCCACACCCTGCAGCGCCCCCCTGCCGGGGGCGCTGGGCGGCTCGGCCGAGGACGCGGACGGGCCGGGGGCGTCCTCGGCCTCCGCCTACCGCGAGGTGTGGCAGGTGAACCTGAAGCCCAAGGGCCTGGGCCAGAGCAAGAACCTGACGGGCGTGTACCGCCTGTGCCTGTCGGCGCGCACCATCGGCTTCGTGAAGCTCAACTGCGAGCAGCCGTCCGTGACGCTGCAGCTCATGAACATCCGCCGCTGCGGCCACTCGGACAGCTTCTTCTTCATAGAGGTGGGGCGCTCGGCCGTCACGGGCCCCGGCGAGCTGTGGATGCAGGCCGACGACTCGGTGGTGGCGCAGAACATCCACGAGACCATCCTGGAGGCCATGAAGGCGCTCAAGGAGCTCTTCGAGTTCCGCCCGCGCAGCAAGAGCCAGTCCTCGGGCTCGTCGGCCACTCACCCCATCAGTGTGCCCGGCGCGCGCCGCCACCACCACCTGGTGCACCTGCCCCCGAGCCAGACCGGCCTGGTGCGCCGCTCGCGCACCGACAGCCTGGCCGCAACCCCGCCCGCCGCCAAGGGCGCCCCGTGTCGCGTGCGTACGGCCAGCGAGGGCGACGGCGGCGCCGCGGCCGGGGCCGGGGCCGGGGCGGCGGTGTCTGCGGCGGGCGCGCGTCCAGGCTCGGTGGCCGGGAGCCCCCTGAGCCCCGGACCGGCGCGCGCGCCCCTGAGCCGCTCGCACACGCTGAGCGCCGGCTGCGGGGCCCGGGGCGGCAAGGCGGGCCTGGCTCCGGCAGGGGGCGCGCTGCAGCACAGCCGCTCCATGTCCATGCCTGTGGCGCACTCTCCCCCTGCTGCCACCAGCCCGGGCAGTCTGTCGTCCAGCAGCGGCCACGGCTCGGCCTCCTACCCGCTGCCGCCCGGCCCGGCCCCGCCGCTGCCGCACCCCCTGCCCCACCCGCTGGGACAGCGACCCTCCAGCGGCAGCGCCTCGGCCTCGGGCTCTCCGAGCGACCCGGGCTTCATGTCCCTGGACGAGTACGGGTCTAGCCCGGGCGACCTGCGAGCCTTCTGCAGCAGCCACCGCAGCAACACGCCCGAGTCCATCGCGGAGACGCCCCCGGCGCGGGATGGCGCGGTGGGCGAGCTGTACGGGTACATGAGCATGGACAGGCCCTCGGGCCCCTTGGGACGCCCCTACCGCAGGGTCTCGGGGGACGCGGCGCAGGACCTGGACCGGGGCCTGCGAAAGCGGACCTACTCGCTGACCACGCCCGCGCGCCAGCGCCCCGTGCCCCAGCCGTCGTCCGCCTCGCTGGATGAGTACACGCTCATGCGGGCCACCTTCTCGGGCAGCTCCGGCCGCCTGTGCCCGCCCTTTCCTGCGTCTTCGCCCAAAGTGGCCTACCACCCCTATCCGGAGGACTATGGGGACATCGAGATCGGCTCACACCGGAGCTCCAGCAGCAACCTGGGGGCGGACGATGGCTACATGCCGATGACCCCTGGTGCAGCTCTGCTGGGCAGTGCCAGCGACGACTACATGCCCATGAGCCCCACCAGCGTGTCTGCCCCGAAGCAGATCCTGCATCCGAGGGCTGCACCGGCCGCGGCCCTGCCCCCCTCGGCGCCACCGGTGCCAGCTGCCCCCTCCCCAGCGGGCAAGACCTTCCCCGGGCCTGTGGGAGGCTACAAGGCCGGCTCACCTGCGGAGAGCTCTCCAGAGGACAGCGGGTACATGCGCATGTGGTGTGGGTCCAAGCTGTCTGTGGAGAGCGCCGACCCCAAGCTGCTGGCCAGCGGGGACTACCTCAACATGTCCCCCAGCGAGGCGGGCCCGGCCGGCACCCCGCCCGACTTCTTCTCCGCAGCTCTGCAGGGCGCTGGGGAGGGGCTCAGAAGTGTCCCCGGCTGCTGCTACAGCTCCTTGCCCCGCTCCTACAAGGGTCCTTACCTGTGTGGCGGGGCAGACAGTGACCAGTACGTGCTCATGAGCTCCCCGGTGGGCCGGATCCTGGAGGAGGAGGGACTGGAGTCCCCGGCCACCCCAGGGGCTCCCCCATGGACGGGCAGGGACAGCCACATCCAGCCGCATCACCTAGCAGCAGCAGTGCCTGCCCCCATGAGGCCAGGCAGCAACGCTGGTGGGCGCCCTGAGGGCTTCTTTGGCCAGCGCTGCCGGGCAGTGCGCCCCACACGCCTGTCCCTAGAGGGCTTGCAGACGCTGCCCAGCATGCATGAGTACCCCCTGCCCCCAGAGCCCAGGAGCCCTGGCGAGTACATCAACATTGACTTCGGGGAGGCGGGCCCCCGGCTGTCCCCGCCGGCCCCTTCGCTGCTGGCGTCTGCGGCCTCACCCTCCCCGCTGCTGTCTGCCAGCAGCCCGGCCTCCTCCCTCTCCCTGGGCTCAGGCACGCCGGGCACCAGCAGTGACAGCAGACAGCGCTCCCCGCTGTCCGACTACATGAACCTGGGCTTCAGCTCCCCCAAGTCCCCCAAGCCGGGGGTCCTGTCCCCCGAGGCCGCTTCCCCATACCCGCCGCTGCCCCCTCGTCCTGCGGCCTCCCTGTCCTCCCTGCAGCAGCAGCCCCCACCGCCGGTCCCCGGGGAGCTGTACCGCCTGCCTCCCGCACCCAGTGCGGCCCCTGCCTCCCAGGGCCCCAGCGCTGGTGCCTCGGTGTCCTCCCAGACTGCTGACAGCAGCGACTACGCCGAGATGGCCTTCGGCCTGGCGGCGCCCCCGAAGCCGGAAGGTGCCCGAGTGAGCAGCCCCACGGCGGGCCTGAAGCGGCTGAGCCTCAGGGGTCAGGGGTCGGGGCTGGAGGCCTTCCTGCAGGCTGGCCAGCCCCCCGACCCGCACCGGGGCGCCAAGGTCATCCGCGCAGACCCGCAGGGGGGCCGCCGCCGCCACAGCTCGGAGACTTTCTCCTCCACTGCCACGGTCACCCCCGTGTCCCCATCCTTCGCTCACAACCCCAAGCGCCACAGCTCGGCCTCTGTGGAGAACGTTTCTCTCCGGAAGAGCAGTGAGAGTGGTGGCGGTGGGGCTGAGGAGCCGCTCACCGCCCCAGGACACTCGACGTTGGCGCGGCCCAGGGCCTCCGGTCAGCCCGGGGGCCTGGGTGGCTGCCCGGCGGGCGGCGGCTCCCCCATGCGCAGAGAAGCCCCCGTGGCTTTTCCGAAAGGCCTCAGCTACATCGCCATCAACGTGAAGGAGGAGGCAGGGCTGTCCCCGCAGATGCCGCCCCCGCAGCCAGGGGACAAGACCTCGTGGGGCCGGACCCGGAGCCTGGGGGGCCTCCTCAGCGCGGTAGGGGGCAGCGGCAGCAGTGGGGCTTGTGGGGGCCCAGGCCCTGCCGCCCTGTCCTCCCCCAACAGCTACGCCAGCCTGGACTTCCTGTCCCATCACCTGAAGGAAGCCACGGCCGTGAAAGAGTGA

Related Sequences

XP_004858614.1 Protein

Irs2 PREDICTED: insulin receptor substrate 2 [Heterocephalus glaber]

Length: 1308 aa      
>XP_004858614.1
MASPPRQGAPGPAGGDGPNLNNNNNNNNNNHGVRKCGYLRKQKHGHKRFFVLRGPGAGGDDGGAGGGPAAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNVNKRADAKHKYLIALYTKDEYFAVAAENEQEQEGWYRALADLLSEGRAAAAGDAPPVATAPAATPCSAPLPGALGGSAEDADGPGASSASAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLVHLPPSQTGLVRRSRTDSLAATPPAAKGAPCRVRTASEGDGGAAAGAGAGAAVSAAGARPGSVAGSPLSPGPARAPLSRSHTLSAGCGARGGKAGLAPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSASYPLPPGPAPPLPHPLPHPLGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSSHRSNTPESIAETPPARDGAVGELYGYMSMDRPSGPLGRPYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSSGRLCPPFPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALLGSASDDYMPMSPTSVSAPKQILHPRAAPAAALPPSAPPVPAAPSPAGKTFPGPVGGYKAGSPAESSPEDSGYMRMWCGSKLSVESADPKLLASGDYLNMSPSEAGPAGTPPDFFSAALQGAGEGLRSVPGCCYSSLPRSYKGPYLCGGADSDQYVLMSSPVGRILEEEGLESPATPGAPPWTGRDSHIQPHHLAAAVPAPMRPGSNAGGRPEGFFGQRCRAVRPTRLSLEGLQTLPSMHEYPLPPEPRSPGEYINIDFGEAGPRLSPPAPSLLASAASPSPLLSASSPASSLSLGSGTPGTSSDSRQRSPLSDYMNLGFSSPKSPKPGVLSPEAASPYPPLPPRPAASLSSLQQQPPPPVPGELYRLPPAPSAAPASQGPSAGASVSSQTADSSDYAEMAFGLAAPPKPEGARVSSPTAGLKRLSLRGQGSGLEAFLQAGQPPDPHRGAKVIRADPQGGRRRHSSETFSSTATVTPVSPSFAHNPKRHSSASVENVSLRKSSESGGGGAEEPLTAPGHSTLARPRASGQPGGLGGCPAGGGSPMRREAPVAFPKGLSYIAINVKEEAGLSPQMPPPQPGDKTSWGRTRSLGGLLSAVGGSGSSGACGGPGPAALSSPNSYASLDFLSHHLKEATAVKE