Details from NCBI annotation

Gene Symbol Hic1
Gene Name hypermethylated in cancer 1, transcript variant X1
Entrez Gene ID 101704969

This gene is present in the GenAge database and has been identified as potentially important to ageing in humans.

Database interlinks

Part of NW_004624786.1 (Scaffold)

For more information consult the page for NW_004624786.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

HIC1 ENSCPOG00000020382 (Guinea pig)

Gene Details

hypermethylated in cancer 1

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000015556, Guinea pig)

Protein Percentage 95.31%
CDS Percentage 90.76%
Ka/Ks Ratio 0.04843 (Ka = 0.0239, Ks = 0.4936)

HIC1 ENSG00000177374 (Human)

Gene Details

hypermethylated in cancer 1

External Links

Gene Match (Ensembl Protein ID: ENSP00000314080, Human)

Protein Percentage 95.86%
CDS Percentage 90.62%
Ka/Ks Ratio 0.02224 (Ka = 0.0178, Ks = 0.799)

Hic1 ENSMUSG00000043099 (Mouse)

Gene Details

hypermethylated in cancer 1

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000053483, Mouse)

Protein Percentage 94.62%
CDS Percentage 86.67%
Ka/Ks Ratio 0.02636 (Ka = 0.0266, Ks = 1.0081)

Hic1 ENSRNOG00000003096 (Rat)

Gene Details

Protein LOC100912068

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000059819, Rat)

Protein Percentage 95.07%
CDS Percentage 87.87%
Ka/Ks Ratio 0.02506 (Ka = 0.0224, Ks = 0.8946)

Genome Location

Sequence Coding sequence

Length: 2178 bp    Location: 4726109..4729709   Strand: +
>XM_004857171.1
ATGACTTTTCCTGAAGTGGACATTTTATTTAAATCGGGAGAGTGTGCTGGGCAGACGATGCTGGACACGATGGAGGCGCCCGGCCACTCGAGGCAGCTGCTGCTGCAGCTCAACAACCAGCGCACCAAGGGCTTCTTGTGCGACGTGATCATCGTGGTGCAGAACGCCCTCTTCCGCGCGCACAAGAACGTGCTGGCCGCCAGCAGTGCCTACCTCAAGTCCCTGGTGGTGCATGACAACCTGCTCAATCTGGACCATGACATGGTGAGCCCGGCCGTGTTCCGCCTGGTGCTGGACTTCATCTACACGGGACGTCTAGCTGACGGCGCAGAGGCAGCTGCAGCGGCGGCAGTGGCCCCGGGGGCTGAGCCGAGCCTGGGTGCGGTGCTGGCCGCTGCCAGCTACCTGCAGATCCCAGACCTTGTGGCGCTGTGCAAGAAGCGCCTCAAGCGCCACGGCAAGTACTGTCACCTGAGGGGAGGTGGCAGCGGCGGCGGCGGTTATGCGCCCTACGGGAGGCCGGGTCGTGGCTTGAGAGCCGCCACGCCCGTCATTCAGGCCTGCTACTCGTCTCCAGCTGGGCCGCCTCCGCCGCCCACCTCCGAGCCACCGTCGGGCCCCGAGGCCGCGGTCAACACGCACTGCGCAGAGCTGTACGCCTCGGGGCCGGGCGCCGCCGCACTGTGCGCTCCGGAGCGTCGCTGCTCTCCGCTCTGCGGCCTGGACCTATCCAAGAAGAGCCCGCCGGGCTCTGCGGTTCCTGAGCGACCCCTGAGTGAGCGAGAGCTGCCCCCGCGCCCGGACACCCCCCCTAGCGCCGGCCCCGCCGCCTATAAGGAGTCCCCTCTCTCCTTGCCGCCGCTGCCGCCCTTCCAGAAGCTGGAGGAGGCCGCGCCCCCGCCCGACCCGTTTCGTGGCAGCGGCAGCAGCCCTGGACCCGAGCCCCCCGGCCGCCCCGACGGGCCTAGCCTCCTCTACCGCTGGATGAAGCACGAGCCGGGCCTGAGTAGCTACGGTGACGAGCTGGGCCGGGAGCGCGGCTCCCCAGGCGAGCGCTGCGAGGAGCGCGGGGGAGACCCGGCCGCCTCGCCTGGGGGCCCCCCGCTCGGCTTGGTGCCGCCGCCACGCTACCCCGGCAGCCTGGACGGGCCTGGTGCGGGCGGCGATGGTGACGACTACAAGAGCAGCAGCGAGGAGACTGGCAGCAGCGAGGATCCCAGCCCGCCTGGCGGGCACCTGGAGGGCTACCCCTGCCCACACCTGGCGTACGGCGAGCCGGAGAGTTTTGGGGACAACTTGTACGTGTGCATCCCGTGCGGCAAGGGCTTCCCCAGCTCCGAGCAGCTGAACGCGCACGTGGAGGCCCATGTAGAGGAGGAGGAGGCGCTGTATGGCAGGGCCGAGGCGGCTGAGGTGGCGGCCGGGGCCCCTTTTGGCAGCGGAGGGGACAAGGTCGCTGGGACTCCAGGCGGCCTAGGAGAGCTGCTGCGGCCATACCGCTGCGCGTCCTGCGACAAGAGCTACAAGGACCCGGCCACGCTGCGGCAGCACGAGAAGACGCATTGGCTGACCCGGCCATATCCGTGCACCATATGCGGGAAGAAGTTCACGCAACGCGGGACCATGACGCGCCATATGCGGAGCCATCTGGGCCTCAAGCCCTTCGCATGCGACGCGTGCGGCATGCGCTTCACGCGCCAGTACCGCCTCACAGAGCACATGCGCATCCACTCGGGTGAGAAGCCCTATGAGTGCCAAGTGTGCGGTGGCAAGTTCGCACAGCAACGCAACCTCATCAGCCACATGAAGATGCACGCTGTGGGTGGCGCGGCTGGCGCAGCTGGGGCGCTGGCAGGTCTAGGGGGCCTACCCGGCGTCCCGGGCCCCGACGGCAAAGGCAAGCTTGACTTTCCCGAGGGTGTCTTTGCTGTGGCCCGCCTCACGGCAGAACAGCTGAGCCTGAAGCAGCAGGACAAGGCCACTGCGGCCGAACTGCTGGCGCAGACCACGCACTTCCTGCACGACCCCAAGGTGGCGCTCGAGAGCCTCTACCCGTTGGCCAAGTTCACCGCGGAGCTGGGCCTCAGCCCAGAAAAGGCGGCCGAGATGCTGAGCCAGGGCGCTCACCTGGCCGTGGGTCCCGACGGCCGGACCATCGATCGTTTCTCTCCCACCTAG

Related Sequences

XP_004857228.1 Protein

Hic1 PREDICTED: hypermethylated in cancer 1 protein isoform X1 [Heterocephalus glaber]

Length: 725 aa     
>XP_004857228.1
MTFPEVDILFKSGECAGQTMLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGSGGGGYAPYGRPGRGLRAATPVIQACYSSPAGPPPPPTSEPPSGPEAAVNTHCAELYASGPGAAALCAPERRCSPLCGLDLSKKSPPGSAVPERPLSERELPPRPDTPPSAGPAAYKESPLSLPPLPPFQKLEEAAPPPDPFRGSGSSPGPEPPGRPDGPSLLYRWMKHEPGLSSYGDELGRERGSPGERCEERGGDPAASPGGPPLGLVPPPRYPGSLDGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYGEPESFGDNLYVCIPCGKGFPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAPFGSGGDKVAGTPGGLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTICGKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHMKMHAVGGAAGAAGALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQLSLKQQDKATAAELLAQTTHFLHDPKVALESLYPLAKFTAELGLSPEKAAEMLSQGAHLAVGPDGRTIDRFSPT