Details from NCBI annotation

Gene Symbol Hmbs
Gene Name hydroxymethylbilane synthase, transcript variant X1
Entrez Gene ID 101700818

Database interlinks

Part of NW_004624784.1 (Scaffold)

For more information consult the page for NW_004624784.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

HMBS ENSCPOG00000006469 (Guinea pig)

Gene Details

hydroxymethylbilane synthase

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000005826, Guinea pig)

Protein Percentage 93.91%
CDS Percentage 92.24%
Ka/Ks Ratio 0.12052 (Ka = 0.0303, Ks = 0.2513)

HMBS ENSG00000256269 (Human)

Gene Details

hydroxymethylbilane synthase

External Links

Gene Match (Ensembl Protein ID: ENSP00000278715, Human)

Protein Percentage 92.24%
CDS Percentage 89.57%
Ka/Ks Ratio 0.11948 (Ka = 0.0416, Ks = 0.3478)

Hmbs ENSMUSG00000032126 (Mouse)

Gene Details

hydroxymethylbilane synthase

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000076575, Mouse)

Protein Percentage 91.97%
CDS Percentage 86.06%
Ka/Ks Ratio 0.07534 (Ka = 0.0429, Ks = 0.5694)

Hmbs ENSRNOG00000010390 (Rat)

Gene Details

hydroxymethylbilane synthase (Hmbs), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000014128, Rat)

Protein Percentage 91.69%
CDS Percentage 86.61%
Ka/Ks Ratio 0.0795 (Ka = 0.0423, Ks = 0.5324)

Genome Location

Sequence Coding sequence

Length: 1086 bp    Location: 14467530..14474950   Strand: +
>XM_004856759.1
ATGTCTGGTAATGGCGTCTCGGCTGCAACGGCGGAAGAAGACGGCTCAAAGATGAGAGTGATTCGAGTGGGTACCCGTAAAAGCCAGTTGGCTCGCATACAGACGGACACTGTTGTGGCAATGCTGAAAGCCTTATACCCTGGCCTGCAGTTTGAAATTGTTGCTATGTCCACCACAGGGGACAAGATTCTTGACACTGCCCTCTCCAAGATTGGAGAGAAGAGCCTATTTACGAAGGAACTGGAATATGCCCTGGAGAGGAATGAAGTGGACCTGGTTGTTCACTCCCTGAAGGACCTGCCTACTGTGCTACCTCCTGGCTTCACCATTGGAGCCATCTGCAAGCGAGAAAGCCCCTACGATGCCGTTGTCTTTCACCCAAAATTTGTGGGGAAGACTCTACAAACCTTGCCAGAGAAGAGCGTGGTGGGGACCAGCTCCCTTCGGAGAGCAGCCCAGCTGCAGAGAAAGTTCCCACATCTGGAGTTCAAGAGCATTCGGGGCAACCTCAACACCCGACTGCGGAAGCTGGACGAACAGCAGGAGTTCAGTGCCATCATCCTGGCTGTTGCTGGCCTGCAGCGTCTGGGCTGGCAGAACAGAGTGGGGCAGATCCTGCACCCTGAGGAGTGTATGTATGCTGTGGGCCAGGGGGCCCTGGGTGTGGAAGTCCGAGCCAAGGACCAGGACGTCTTGAATCTAGTGGATGTGTTGCATGATCCTGAGACTCTGCTTCGTTGCATCGCCGAAAGGGCCTTCCTGAGGCACTTGGAAGGAGGCTGCAGTGTGCCAGTGGCGGTGCACACCGTGATGAAGGATGGGCAACTGTACTTGACTGGAGGAGTCTGGAGTCTAGATGGCTCAGATAGCATGCAAGAGACTATGCAGGCTACCATCCATGTCCCTGTCCAGCATGAGGATGGCCCAGAGGATGATCCCCAGCTGGTCGGCATCACTGCCCAGAACATTCCACGAGGAGCCCAACTGGCTGCTGAGAACTTGGGCATCAGCCTGGCCAATCTGTTGCTAAGCAAAGGAGCCAAAAACATCCTGGATGTCGCACGGCAGCTTAATGATGTCCATTAA

Related Sequences

XP_004856816.1 Protein

Hmbs PREDICTED: porphobilinogen deaminase isoform X1 [Heterocephalus glaber]

Length: 361 aa      View alignments
>XP_004856816.1
MSGNGVSAATAEEDGSKMRVIRVGTRKSQLARIQTDTVVAMLKALYPGLQFEIVAMSTTGDKILDTALSKIGEKSLFTKELEYALERNEVDLVVHSLKDLPTVLPPGFTIGAICKRESPYDAVVFHPKFVGKTLQTLPEKSVVGTSSLRRAAQLQRKFPHLEFKSIRGNLNTRLRKLDEQQEFSAIILAVAGLQRLGWQNRVGQILHPEECMYAVGQGALGVEVRAKDQDVLNLVDVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTVMKDGQLYLTGGVWSLDGSDSMQETMQATIHVPVQHEDGPEDDPQLVGITAQNIPRGAQLAAENLGISLANLLLSKGAKNILDVARQLNDVH