Details from NCBI annotation

Gene Symbol Bace1
Gene Name beta-site APP-cleaving enzyme 1, transcript variant X2
Entrez Gene ID 101701890

Database interlinks

Part of NW_004624784.1 (Scaffold)

For more information consult the page for NW_004624784.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

BACE1 ENSCPOG00000012754 (Guinea pig)

Gene Details

Cavia porcellus beta-site APP cleaving enzyme 1 (Bace1), mRNA.

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000011476, Guinea pig)

Protein Percentage 98.31%
CDS Percentage 94.71%
Ka/Ks Ratio 0.03207 (Ka = 0.0076, Ks = 0.2369)

BACE1 ENSG00000186318 (Human)

Gene Details

beta-site APP-cleaving enzyme 1

External Links

Gene Match (Ensembl Protein ID: ENSP00000318585, Human)

Protein Percentage 97.46%
CDS Percentage 92.95%
Ka/Ks Ratio 0.03458 (Ka = 0.0114, Ks = 0.3293)

Bace1 ENSMUSG00000032086 (Mouse)

Gene Details

beta-site APP cleaving enzyme 1

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000034591, Mouse)

Protein Percentage 97.04%
CDS Percentage 90.06%
Ka/Ks Ratio 0.02706 (Ka = 0.0143, Ks = 0.5283)

Bace1 ENSRNOG00000016847 (Rat)

Gene Details

beta-site APP cleaving enzyme 1 (Bace1), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000022796, Rat)

Protein Percentage 96.83%
CDS Percentage 90.91%
Ka/Ks Ratio 0.03696 (Ka = 0.0162, Ks = 0.439)

Genome Location

Sequence Coding sequence

Length: 1422 bp    Location: 12759526..12725419   Strand: -
>XM_004856668.1
ATGGCCCCAGCTCTGCCCTGGCTCCTGCTGTGGGTGGGCTCGGGAGTGCTGCCTGCCCACGGCACCCAGCACAGCATCCGACTGCCCCTGCGCAGCGGCCTGGCAGGGGCGCCCCTGGGGCTGAGGTTGCCGCGGGAGACTGACGAGGAGCTCGGCAGGAGGGGCAGCTTCGTGGAGATGGTGGACAACCTGAGGGGCAAGTCGGGCCAGGGCTACTACGTGGAGATGACCGTGGGAAGCCCGCCACAGACGCTCAACATCCTGGTGGACACAGGCAGCAGTAACTTTGCAGTGGGGGCTGCCCCCCACCCTTTCCTGCATCGCTACTACCAAAGGCAGCGATCCAGCACGTATCGGGACCTCCGGAAGGGCGTGTATGTGCCCTACACCCAGGGCAAGTGGGAAGGGGAGCTGGGCACCGACCTGGTGAGCATTCCTCATGGTCCCAACGTCACTGTACGTGCGAACATCGCTGCCATCACTGAATCAGACAAGTTCTTCATCAATGGCTCCAACTGGGAGGGCATCCTGGGGCTGGCCTATGCTGAGATCGCCAGGCTCTGTGGTGCAGGCTTCCCCCTCAACCAGTCTGAGGCTGTGGCCTCTGTTGGAGGGAGCATGATCATTGGGGGTATCGATCACTCACTATATACAGGCAGTCTCTGGTACACACCCATCCGACGGGAGTGGTATTATGAGGTGATCATTGTGCGGGTAGAGATCAATGGACAAGATCTGAAGATGGACTGCAAGGAGTACAACTATGACAAGAGCATCGTGGACAGTGGCACCACCAACCTTCGTCTTCCCAAGAAAGTGTTTGAGGCTGCAGTCAAATCCATCAAGGCAGCCTCCTCGACAGAGAAGTTCCCAGATGGTTTTTGGCTAGGGGAGCAGCTGGTGTGCTGGCAAGCAGGCACCACGCCTTGGAACATTTTCCCAGTCATCTCGCTCTACCTCATGGGTGAGGTCACCAATCAGTCCTTCCGCATCACCATCCTTCCCCAGCAATACCTTCGGCCTGTGGAAGACGTGGCCACATCCCAAGATGACTGTTACAAGTTCGCCATCTCACAGTCATCCACTGGCACGGTTATGGGAGCTGTTATTATGGAGGGCTTCTACGTTGTCTTTGATCGGGCCCAAAAACGAATCGGCTTTGCTGTCAGTGCTTGCCACGTGCATGATGAGTTCAGGACAGCAGCAGTGGAAGGCCCTTTTGTCACCCTGGACATGGAAGACTGTGGCTACAACATTCCACAGACAGACGAATCGACCCTCATGACCATAGCTTATGTCATGGCTGCCATCTGTGCCCTCTTCATGCTGCCACTATGCCTCATGGTATGTCAGTGGCGCTGCCTCCGCTGCCTCCGCCATCAGCATGATGACTTTGCTGATGACATCTCCCTGCTGAAATGA

Related Sequences

XP_004856725.1 Protein

Bace1 PREDICTED: beta-secretase 1 isoform X2 [Heterocephalus glaber]

Length: 473 aa      View alignments
>XP_004856725.1
MAPALPWLLLWVGSGVLPAHGTQHSIRLPLRSGLAGAPLGLRLPRETDEELGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQRSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARLCGAGFPLNQSEAVASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRAQKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCLRHQHDDFADDISLLK