Details from NCBI annotation

Gene Symbol Ercc4
Gene Name excision repair cross-complementing rodent repair deficiency, complementation group 4
Entrez Gene ID 101717694

This gene is present in the GenAge database and has been identified as potentially important to ageing in humans.

Database interlinks

Part of NW_004624782.1 (Scaffold)

For more information consult the page for NW_004624782.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

ERCC4 ENSCPOG00000004495 (Guinea pig)

Gene Details

excision repair cross-complementing rodent repair deficiency, complementation group 4

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000004055, Guinea pig)

Protein Percentage 94.36%
CDS Percentage 93.48%
Ka/Ks Ratio 0.18804 (Ka = 0.0329, Ks = 0.175)

ERCC4 ENSG00000175595 (Human)

Gene Details

excision repair cross-complementing rodent repair deficiency, complementation group 4

External Links

Gene Match (Ensembl Protein ID: ENSP00000310520, Human)

Protein Percentage 92.14%
CDS Percentage 89.12%
Ka/Ks Ratio 0.11247 (Ka = 0.0418, Ks = 0.3715)

Ercc4 ENSMUSG00000022545 (Mouse)

Gene Details

excision repair cross-complementing rodent repair deficiency, complementation group 4

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000023206, Mouse)

Protein Percentage 87.01%
CDS Percentage 80.57%
Ka/Ks Ratio 0.08341 (Ka = 0.0772, Ks = 0.9253)

Genome Location

Sequence Coding sequence

Length: 2751 bp    Location: 4537727..4511123   Strand: -
>XM_004855848.1
ATGGAGCCGCGATTTTCGGCTCGACGGATCGCTATGGCGCCGCTGCTAGAATATGAGAGGCAGCTGGTGCTGGAGCTGCTCGACACCGACGGGCTGGTCGTGTGCGCCCGAGGGCTCGGCGCGGACCGGCTCCTCTACCATTTCCTCCGGCTACACTGCCACCCGGCCTGCCTGGTGCTGGTGCTCAACACGCAGCCAGCCGAGGAGGAGTATTTTATCAATCAGCTGAAGATAGAAGGAGTCGATCACCTCCCTCGCCGTGTGACAAATGAAATCGCAAGTAACAGTCGCTATGAGGTTTACACACAAGGTGGTGTTATATTTGCAACAAGTCGAATACTTGTGGTTGATTTTTTGACTGATAGAATACCTTCAGATTTAATAACTGGGATCTTGGTGTATAGAGCCCACCGAATCATCGAGTCTTGTCAGGAAGCATTCATTTTGCGCCTCTTTCGCCAGAAAAACAAACGTGGTTTTATTAAAGCTTTCACAGACAACGCCGTCGCCTTTGATACTGGTTTTTGTCATGTGGAAAGAGTGATGAGAAATCTTTTTGTGAGGAAGCTGTATCTGTGGCCTAGGTTCCATGTAGCAGTCAACTCATTTTTAGAACATCATAAACCTGAAGTTGTAGAAATTCATGTTTCTATGACACCTGCCATGCTTGCCATCCAAACTGCTATACTGGATATTTTAAATGCATGTCTAAAGGAACTGAAAAGTCATAACCCATCGCTGGAAGTGGAAGATTTATCTTTAGAAAATGCTATTGGGAAGCCTTTTGACAAGACAATCCGCCATTATCTGGATCCTTTGTGGCATCAGCTTGGAGCCAAGACTAAATCTTTGGTTCAGGATTTGAAGATATTGCGGACTTTGCTGCAGTATCTCTCACAATATGATTGTGTCACATTTCTTAATCTTTTGGAATCTCTGAGAGCAACAGAAAAGGCTTTTGGTCAGAATTCAGGTTGGCTATTTCTTGACTCCAGCACCTCAATGTTCATAAACGCTCGGGCAAGGGTTTATCATATTCCAGATGCCAAAATGAGTAAGAAAAGCAAAATGCCTGAAAAAATGGAGATTAAGGAAGGACAAGAAACAAAAAAGGAACTGGTCCTGGAAAACAACCCGAAGTGGGAGGCACTAACTGAAGTATTGAAAGAAATTGAGGCAGAAAATAAGGAGAGTGAAGCCCTTGGAGGCCCAGGTCAAGTTCTTATCTGTGCAAGTGATGACCGCACGTGCTCCCAGCTGAAAGACTACCTCACCGCTGGGGCAGAGGCCTTTTTACTGCAGCTCTACAGGAAGACCTTTGAGAAAGACAGCAAAGCGGAGGAAGTATGGGTGAAATTTAGAAAGGAGCATGGTTCAAAGAGAACTACAAAATCTAACAAAAGACCCAAAGATCTCCAGCATAAAGAACGGGGTTCTGTCAAAGAAAAAATTCCCAAAAAGAAAAAACGAAGGTTGACTCTAACTCAGATGCCAGGACAATCTGAAGAAGTGGAAGAGGAAGAGGGTGTTGAGGAAGGACATCCTAGAGACAGAAGCAGTAGCCCAGAAGTCTGCTTGGGAGAAATCAAGCATGAGGAATTTGATTTAAATTTGTCGTCTGATGCTGCTTATGGACTCTTGAAAGAACCCCTCACCATCCTCCATCCTCTCCTGGGTTGTAGCGACCCCTATGCTCTGACGAGGGTTCTCCATGAGGTGGAGCCAAGATTCGTGGTTCTGTATGATGCAGAGCTCACGTTCGTTCGTCAGCTTGAAATTTACAGGGCAAGCAGGCCGGGGAAACCTCTGAGGGTTTACTTTCTCATATATGGTGGATCAACAGAGGAACAACGTTATCTCACTGCTCTGCGAAAAGAAAAGGAAGCTTTTGAAAAACTCATAAGGGAAAAGGCTAGCATGGTTGTCCCTGAAGAAAGAGAAGGCAGAGATGAAACCAACCTGGACTTAGCAAGAGGCACAGCATCGACACATGCTGCCGCTGACACCCGCAAAGCTGGTGGCCAGGAACAGAATGGAACACAGCAAAGCATAGTTGTGGACATGCGTGAATTCCGAAGTGAGCTCCCATCTCTGATCCATCGCCGGGGCATTGACATTGAACCTGTGACTTTAGAGGTTGGAGATTACATCCTGACACCAGAAATGTGCGTGGAGCGCAAGAGCATCAGTGACCTGATCGGTTCTCTGAATAATGGCCGCCTGTACAGCCAGTGCATCTCTATGTCCCGCTACTACAAGCGCCCTGTGCTCCTGATCGAGTTTGACCCCAGTAAGCCCTTCTCTCTCTCAGCCCGAGGTGCCTTATTTCAGGAGATCTCCAGCAGTGACATTAGTTCCAAACTCACCCTTCTCACGCTTCACTTCCCCAGACTTCGCCTCCTCTGGTGCCCTTCCCCTCATGCAACAGCAGAGCTATTTGAAGAACTCAAGCAAAATAAGCCACAGCCTGATGCAGCCACAGCCATGGCCATTACAGCAGATTCTGAGACCCTGCCTGAGTCAGAAAAGTATAATCCTGGTCCCCAAGACTTCTTGTTAAAAATGCCAGGGGTAAATGCCAAAAACTGTCGCTCCTTGATGAACCACGTTAAGAACATTGCAGAATTAGCAACCCTATCACAAGACAAGCTCACAGGTATTCTGGGGCATGCCGCAAATGCTAAGCAGCTTTATGACTTCATTCACACCACTTACGCAGAAGTGGTGTCTAAAGGGAAAGTGAAAAAGTGA

Related Sequences

XP_004855905.1 Protein

Ercc4 PREDICTED: DNA repair endonuclease XPF [Heterocephalus glaber]

Length: 916 aa     
>XP_004855905.1
MEPRFSARRIAMAPLLEYERQLVLELLDTDGLVVCARGLGADRLLYHFLRLHCHPACLVLVLNTQPAEEEYFINQLKIEGVDHLPRRVTNEIASNSRYEVYTQGGVIFATSRILVVDFLTDRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEHHKPEVVEIHVSMTPAMLAIQTAILDILNACLKELKSHNPSLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEKAFGQNSGWLFLDSSTSMFINARARVYHIPDAKMSKKSKMPEKMEIKEGQETKKELVLENNPKWEALTEVLKEIEAENKESEALGGPGQVLICASDDRTCSQLKDYLTAGAEAFLLQLYRKTFEKDSKAEEVWVKFRKEHGSKRTTKSNKRPKDLQHKERGSVKEKIPKKKKRRLTLTQMPGQSEEVEEEEGVEEGHPRDRSSSPEVCLGEIKHEEFDLNLSSDAAYGLLKEPLTILHPLLGCSDPYALTRVLHEVEPRFVVLYDAELTFVRQLEIYRASRPGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLARGTASTHAAADTRKAGGQEQNGTQQSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPEMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLSARGALFQEISSSDISSKLTLLTLHFPRLRLLWCPSPHATAELFEELKQNKPQPDAATAMAITADSETLPESEKYNPGPQDFLLKMPGVNAKNCRSLMNHVKNIAELATLSQDKLTGILGHAANAKQLYDFIHTTYAEVVSKGKVKK