Details from NCBI annotation

Gene Symbol Ppp1ca
Gene Name protein phosphatase 1, catalytic subunit, alpha isozyme, transcript variant X1
Entrez Gene ID 101705408

This gene is present in the GenAge database and has been identified as potentially important to ageing in humans.

Database interlinks

Part of NW_004624767.1 (Scaffold)

For more information consult the page for NW_004624767.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

PPP1CA ENSCPOG00000011166 (Guinea pig)

Gene Details

protein phosphatase 1, catalytic subunit, alpha isozyme

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000010040, Guinea pig)

Protein Percentage 100.0%
CDS Percentage 95.05%
Ka/Ks Ratio 0.001 (Ka = 0.0002, Ks = 0.2288)

PPP1CA ENSG00000172531 (Human)

Gene Details

protein phosphatase 1, catalytic subunit, alpha isozyme

External Links

Gene Match (Ensembl Protein ID: ENSP00000326031, Human)

Protein Percentage 100.0%
CDS Percentage 92.53%
Ka/Ks Ratio 0.001 (Ka = 0.0005, Ks = 0.4508)

Ppp1ca ENSMUSG00000040385 (Mouse)

Gene Details

protein phosphatase 1, catalytic subunit, alpha isoform

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000039109, Mouse)

Protein Percentage 99.7%
CDS Percentage 91.31%
Ka/Ks Ratio 0.00272 (Ka = 0.0014, Ks = 0.4974)

Ppp1ca ENSRNOG00000018708 (Rat)

Gene Details

protein phosphatase 1, catalytic subunit, alpha isozyme (Ppp1ca), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000025282, Rat)

Protein Percentage 100.0%
CDS Percentage 90.91%
Ka/Ks Ratio 0.001 (Ka = 0.0005, Ks = 0.542)

Genome Location

Sequence Coding sequence

Length: 993 bp    Location: 19120688..19123934   Strand: +
>XM_004852245.1
ATGTCCGACAGCGAGAAGCTCAACCTGGACTCTATCATCGGGCGCCTGCTGGAAGTGCAGGGCTCGAGGCCTGGAAAGAATGTACAGCTGACAGAGAACGAGATCCGTGGTCTGTGCCTCAAATCCCGGGAGATTTTCCTGAGCCAGCCCATTCTTCTGGAGCTGGAGGCCCCCCTCAAGATCTGTGGTGATATCCATGGCCAGTATTACGACCTTCTGCGGCTGTTTGAGTATGGCGGCTTCCCTCCAGAGAGCAACTACCTCTTCCTGGGGGACTATGTGGACCGGGGCAAACAGTCTTTGGAGACCATCTGCCTGCTGCTGGCCTATAAGATCAAGTACCCCGAGAATTTCTTCCTTCTCCGAGGGAACCATGAGTGTGCCAGCATCAACCGTATCTATGGCTTCTATGATGAGTGCAAGAGACGCTACAACATCAAATTATGGAAAACCTTCACTGATTGCTTCAACTGCCTGCCCATTGCTGCCATTGTGGATGAGAAAATCTTCTGTTGCCATGGAGGCCTGTCCCCAGACTTACAGTCCATGGAGCAGATTCGGCGCATCATGCGGCCCACAGACGTGCCTGATCAAGGCCTGCTATGTGACCTGCTGTGGTCTGACCCTGACAAGGATGTGCAGGGCTGGGGCGAGAACGACCGTGGTGTCTCCTTTACTTTTGGGGCTGAGGTGGTGGCCAAGTTTCTGCACAAGCATGATTTGGACCTCATCTGCCGGGCACACCAGGTGGTGGAAGATGGTTATGAGTTCTTTGCCAAGCGGCAGCTGGTAACACTTTTCTCAGCCCCTAATTACTGTGGCGAGTTTGACAATGCTGGTGCCATGATGAGTGTGGATGAGACCCTCATGTGCTCCTTCCAGATCCTCAAGCCCGCTGACAAGAACAAGGGGAAGTACGGGCAGTTCAGTGGCCTGAACCCTGGAGGCCGACCCATTACCCCACCCCGAAACTCTGCCAAAGCCAAGAAATAA

Related Sequences

XP_004852302.1 Protein

Ppp1ca PREDICTED: serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform X1 [Heterocephalus glaber]

Length: 330 aa      View alignments
>XP_004852302.1
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK