Details from NCBI annotation

Gene Symbol Tpmt
Gene Name thiopurine S-methyltransferase, transcript variant X5
Entrez Gene ID 101703237

Database interlinks

Part of NW_004624756.1 (Scaffold)

For more information consult the page for NW_004624756.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

TPMT ENSCPOG00000005295 (Guinea pig)

Gene Details

thiopurine S-methyltransferase

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000004763, Guinea pig)

Protein Percentage 86.42%
CDS Percentage 89.85%
Ka/Ks Ratio 0.23332 (Ka = 0.0657, Ks = 0.2817)

TPMT ENSG00000137364 (Human)

Gene Details

thiopurine S-methyltransferase

External Links

Gene Match (Ensembl Protein ID: ENSP00000312304, Human)

Protein Percentage 76.64%
CDS Percentage 82.65%
Ka/Ks Ratio 0.24519 (Ka = 0.1311, Ks = 0.5345)

Tpmt ENSMUSG00000021376 (Mouse)

Gene Details

thiopurine methyltransferase

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000021806, Mouse)

Protein Percentage 74.9%
CDS Percentage 80.47%
Ka/Ks Ratio 0.23726 (Ka = 0.147, Ks = 0.6196)

Tpmt ENSRNOG00000016468 (Rat)

Gene Details

thiopurine S-methyltransferase (Tpmt), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000022084, Rat)

Protein Percentage 71.55%
CDS Percentage 76.99%
Ka/Ks Ratio 0.24408 (Ka = 0.1823, Ks = 0.7469)

Genome Location

Sequence Coding sequence

Length: 735 bp    Location: 8511320..8531734   Strand: +
>XM_004847627.1
ATGAATGATACAAGAACTTCACTTGATATTAAAGAGTACCCTGATAGTGAGGTACAGAAAAACCGAATAATAACCCAGGAAGAATGGCAAGACAATTGGGTGAATCACAAAATCGGATTTCATCAAGCAGAAGGGCATCAGCTGTTAAAGAAGCATTTGGATAATTTTCTTAAAGGCGAGAGTGGACTGAGAGTGTTTTTTCCTCTTTGTGGAAAAGCAGTGGAGATGAAATGGTTTGCTGATCTAGGACACAGTGTAATTGGTGTAGAAATCAGTGAACTTGGGATACGAGAATTTTTTATGGAGCAGAATCTTTCTTACTCAGAAGAACCAATCACTGAACTTCCTGGTGCAAAAGTATTTAAGAGTTCTTCAGGGAATATTTCACTGTACTGCTGCAGCATTTTCGATCTTCCCAGAGCAAATATCGGTAAATTTGACAGGATTTGGGATAGAGGAGCGTTAGTCGCTGTTAATCCAAGTGACCGTGGACGCTACACAGATATAATGCTGTCCCTACTGAGAAAAGGGTTTCTCTACCTTGTGTCCATTTTCTCTTACGATCCAACAAAATTTGAAGGCCCACCATTTTATGTTCCAGATTCTGAAGTCCAAACACTCTTTGGTACAAAGTGCAATATCCATTGCCTTGAAAAGGTCGATGCTATTGAAAAACGAAAGAATGCGGGAACTGACTACTTTTTTGAAAAATTATATCTACTTACAGAAAGGTAG

Related Sequences

XP_004847684.1 Protein

Tpmt PREDICTED: thiopurine S-methyltransferase isoform X5 [Heterocephalus glaber]

Length: 244 aa      View alignments
>XP_004847684.1
MNDTRTSLDIKEYPDSEVQKNRIITQEEWQDNWVNHKIGFHQAEGHQLLKKHLDNFLKGESGLRVFFPLCGKAVEMKWFADLGHSVIGVEISELGIREFFMEQNLSYSEEPITELPGAKVFKSSSGNISLYCCSIFDLPRANIGKFDRIWDRGALVAVNPSDRGRYTDIMLSLLRKGFLYLVSIFSYDPTKFEGPPFYVPDSEVQTLFGTKCNIHCLEKVDAIEKRKNAGTDYFFEKLYLLTER