Details from NCBI annotation

Gene Symbol Ppargc1a
Gene Name peroxisome proliferator-activated receptor gamma, coactivator 1 alpha, transcript variant X1
Entrez Gene ID 101703716

This gene is present in the GenAge database and has been identified as potentially important to ageing in humans.

Database interlinks

Part of NW_004624755.1 (Scaffold)

For more information consult the page for NW_004624755.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

PPARGC1A ENSCPOG00000001518 (Guinea pig)

Gene Details

peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000001373, Guinea pig)

Protein Percentage 95.47%
CDS Percentage 94.8%
Ka/Ks Ratio 0.23648 (Ka = 0.0298, Ks = 0.1258)

PPARGC1A ENSG00000109819 (Human)

Gene Details

peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

External Links

Gene Match (Ensembl Protein ID: ENSP00000264867, Human)

Protein Percentage 95.47%
CDS Percentage 93.79%
Ka/Ks Ratio 0.15029 (Ka = 0.0278, Ks = 0.1849)

Ppargc1a ENSMUSG00000029167 (Mouse)

Gene Details

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000117040, Mouse)

Protein Percentage 92.08%
CDS Percentage 91.28%
Ka/Ks Ratio 0.1707 (Ka = 0.0444, Ks = 0.2599)

Ppargc1a ENSRNOG00000004473 (Rat)

Gene Details

peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (Ppargc1a), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000006071, Rat)

Protein Percentage 92.45%
CDS Percentage 91.15%
Ka/Ks Ratio 0.1662 (Ka = 0.0433, Ks = 0.2606)

Genome Location

Sequence Coding sequence

Length: 2409 bp    Location: 8166577..8460746   Strand: +
>XM_004847207.1
ATGGATGAGACCTCTCCCAGGCTGGAAGAAGACTGGAAAAAAGAACTTCAGCAAGAAGCAGGCTGGCAGTGTGCTGCTTTGGTTGGTGAAGACCAGCCCCTTTGCCCAGATCTTCCTGAACTTGATCTTTCTGAACTAGATGTGAACGACTTGGATACAGACAGCTTTCTGGGTGGACTGAAGTGGTGCAGTGACCAATCAGAAATAATATCCAACCAGTACAACAATGAGCCTTCAAACATATTTGAGAAGATAGATGAAGAAAATGAGGCAAACTTGCTAGCTGTCCTCACAGAGACACTGGACAGTCTCCCTGTGGACGAAGACGGATTGCCCTCATTTGACGCACTGACAGATGGAGACGTGACTACTGACAACGAGGCCAGTCCTTCCTCCATGCCTGACGGCACCCCTCCACCTCAGGAGGCAGAAGAGCCATCTCTACTTAAGAAGCTCTTACTGGCACCGGCAAATACTCAGCTGAGTTATAATGAATGCAGTGGTCTCAGTACCCAGAACCATGCAAACCACAATCACAGGATCAGAACAAACCCTGCAGTTGTTAAGACCGAGAATTCATGGAGCAATAAAACAAAGAGCATTTGTCAACAGCAAAAGCCACAAAGACGTCCCTGCTCGGAGCTTCTCAAGTATCTGACCACAAATGATGACCCTCCTCACACCAAACCCACAGAGAACAGGAACAGCAGCAGAGACAAATGCACTTCCAAAAAGAAGTCCCACACACAATCGCAGTCCCAACATGTACAAGCCAAACCAACAACTTTATCTCTTCCTCTGACCCCAGAGTCACCAAATGACCCCAAGGGTTCCCCATTTGAGAACAAGACTATTGAACGAACCTTAAGTGTGGAACTCTCTGGAACTGCAGGCCTAACTCCACCTACAACTCCTCCTCATAAAGCCAACCAAGATAACCCTTTCAGGGCTTCTCCAAAGCTGAAGTCCTCTTGCAAGACAGTGGTGCCACCGCCATCAAAGAAGCCCCGGCACAGTGAGTCTTCTGGTACCCAAGTCAATAACTCCACCAAGAAGGGGCCCGAGCAATCTGAGTTGTATGCACAACTCAGCAAGTCCTCAGTGCTCGGAAGTGGACAAGAGGAGAGGAAGACTAAGCGGCCCAGCCTACGGCTGTTTGGTGACCATGACTATTGTCAGTCCATTAATTCCAAAACAGAAATAATTATTAATATATCACAAGAGCTCCAAGACTCTAGACAACTAGACTATAAAGATGCCTCCTCTGACTGGCAGGGGCAGGTTTGTTCTTCCACAGATTCAGACCAGTGCTACCTGAGAGAGACTTTGGAGGCCAGCAAGCAGCTCTCTCCTTGCAGCACCAGAAAACAGCTCCAGGACCAGGAAATCCGAGCCGAGCTGAACAAGCATTTCGGTCATCCCAGTCAAGCTGTTTTTGACGACGAAGCAGACAAGACCAGTGAACTGAGGGACAGTGATTTCAGTAATGAACAATTCTCCAAACTACCTATGTTTATAAATTCAGGACTAGCCATGGATGGCCTGTTTGATGACAGCGAAGATGAAAGTGATAAACTGAGCTACCCTTGGGATGGCACGCAATCCTATTCATTGTTTGATGTGTCGCCTTCCTGCTCTTCTTTTAACTCTCCATGTAGAGATTCCGTGTCGCCACCCAAATCCTTATTTTCTCAAAGACCCCAAAGGATGCGCTCTCGTTCAAGGTCCTTTTCTCGACACAGGTCATGTTCCCGATCACCTTATTCCAGATCAAGATCAAGGTCCCCAGGCAGTAGATCTTCAAGATCCTGCTACTACTATGAATCAAGCCACTACAGACACCACACGCACCGAAACTCTCCCTTGTATGTGAGATCACGTTCAAGATCACCCTACAGCCGTAGGCCCAGGTATGACAGCTACGAGGCATATCAGCATGAAAGGCTGAAGAGGGAAGAATACCGGAAAGAGTACGACAAGCGGGAATCTGAAAGGGCCAAACAGAGGGAGAGGCAGAGGCAGAAGGCAATTGAAGAGCGCCGTGTGATTTACATCGATAAAATCAGACCTGACACAACACGGACAGAACTGAGGGACCGCTTTGAAGTTTTTGGTGAAATTGAGGAGTGCACAGTAAATCTGCGGGATGATGGAGACAGCTATGGTTTCATCACCTATCGTTATACCTGTGACGCTTTTGCTGCTCTTGAAAATGGATATACTTTGCGCAGGTCGAACGAAATGGACTTCGAGCTGTACTTTTGTGGACGCAAGCAATTTTTCAAGTCTAACTATGCAGACTTAGATTCAAACTCAGATGACTTTGACCCTGCTTCCACCAAGAGCAAGTATGACTCTCTGGATTTTGATAGTTTACTGAAAGAAGCTCAGAGAAGCTTGCGCAGGTAA

Related Sequences

XP_004847264.1 Protein

Ppargc1a PREDICTED: peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1 [Heterocephalus glaber]

Length: 802 aa      View alignments
>XP_004847264.1
MDETSPRLEEDWKKELQQEAGWQCAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEPSNIFEKIDEENEANLLAVLTETLDSLPVDEDGLPSFDALTDGDVTTDNEASPSSMPDGTPPPQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHANHNHRIRTNPAVVKTENSWSNKTKSICQQQKPQRRPCSELLKYLTTNDDPPHTKPTENRNSSRDKCTSKKKSHTQSQSQHVQAKPTTLSLPLTPESPNDPKGSPFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKLKSSCKTVVPPPSKKPRHSESSGTQVNNSTKKGPEQSELYAQLSKSSVLGSGQEERKTKRPSLRLFGDHDYCQSINSKTEIIINISQELQDSRQLDYKDASSDWQGQVCSSTDSDQCYLRETLEASKQLSPCSTRKQLQDQEIRAELNKHFGHPSQAVFDDEADKTSELRDSDFSNEQFSKLPMFINSGLAMDGLFDDSEDESDKLSYPWDGTQSYSLFDVSPSCSSFNSPCRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSRSCYYYESSHYRHHTHRNSPLYVRSRSRSPYSRRPRYDSYEAYQHERLKREEYRKEYDKRESERAKQRERQRQKAIEERRVIYIDKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNEMDFELYFCGRKQFFKSNYADLDSNSDDFDPASTKSKYDSLDFDSLLKEAQRSLRR