Details from NCBI annotation

Gene Symbol Epm2a
Gene Name epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
Entrez Gene ID 101709129

Database interlinks

Part of NW_004624753.1 (Scaffold)

For more information consult the page for NW_004624753.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

EPM2A ENSCPOG00000002055 (Guinea pig)

Gene Details

epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000001860, Guinea pig)

Protein Percentage 93.51%
CDS Percentage 91.2%
Ka/Ks Ratio 0.13758 (Ka = 0.0391, Ks = 0.2841)

EPM2A ENSG00000112425 (Human)

Gene Details

epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)

External Links

Gene Match (Ensembl Protein ID: ENSP00000356489, Human)

Protein Percentage 92.16%
CDS Percentage 89.05%
Ka/Ks Ratio 0.07891 (Ka = 0.0384, Ks = 0.4862)

Epm2a ENSMUSG00000055493 (Mouse)

Gene Details

epilepsy, progressive myoclonic epilepsy, type 2 gene alpha

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000066050, Mouse)

Protein Percentage 87.69%
CDS Percentage 86.57%
Ka/Ks Ratio 0.11082 (Ka = 0.0637, Ks = 0.5747)

Epm2a ENSRNOG00000040242 (Rat)

Gene Details

epilepsy, progressive myoclonus type 2A (Epm2a), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000058646, Rat)

Protein Percentage 88.43%
CDS Percentage 86.32%
Ka/Ks Ratio 0.08944 (Ka = 0.057, Ks = 0.6371)

Genome Location

Sequence Coding sequence

Length: 807 bp    Location: 8715898..8805728   Strand: +
>XM_004846126.1
ATGAGGGTCCGCTTCGGCGTGGTGCTGGCGGCCGCCGAGGAGCCGGGCCGAGTGGAGCCCTTCTGGTACAAGTTCCTGAAGCGCGAGCCCGGAGGAGAGCTCTGCTGGGAAGGCAATGGGCCTCACCACGATCGTTGCTGTACTTACAATGAAAACAACTTGGTGGATGGTGTTTACTGTCTCCCAATAGGACACTGGATTGAGGCCACTGGGCACACGAATGAGATGAAGCACACAACAGACTTCTATTTTAATATTGCAGGCCACCAAGCCATGCATTATTCAAGAATTCTACCAAATATCTGGCTGGGTAGCTGCCCTCGGCAAGTGGAACATGTGACCATCAAACTGAAGCATGAACTGGGGATTACAGCTGTCATGAATTTCCAGACGGAAAGCGATATTGTCCAGAATTCTTCAGGCTGCAACCGCTACCCTGAACCCATGACCCCTGACACTATGATTAGACTGTATAAAGAAGAAGGCTTGGTCTACATCTGGATGCCAACAGCAGACATGAGTACTGAAGGCCGTGTGCAGATGCTGCCCCAGGCCGTGTGCCTCCTGCACATGCTTCTCGAGAATGGCCACACCGTGTACGTCCACTGCAATGCCGGGGTGGGCCGCTCCGCCGCGGCCGTGTGCGGGTGGCTGCAGTACGTGATGGGCTGGAACCTGAGGAAGGTGCAGTACTTCCTCATGGCCAAGAGGCCAGCCGTGTACATTGATGAAGAGGCCCTGGGACGGGCACAAGAAGACTTTTACCAGAAGTTTGGGAAGCTTCGTTCTTCCATATGCAATCTGTAG

Related Sequences

XP_004846183.1 Protein

Epm2a PREDICTED: laforin [Heterocephalus glaber]

Length: 268 aa      View alignments
>XP_004846183.1
MRVRFGVVLAAAEEPGRVEPFWYKFLKREPGGELCWEGNGPHHDRCCTYNENNLVDGVYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTESDIVQNSSGCNRYPEPMTPDTMIRLYKEEGLVYIWMPTADMSTEGRVQMLPQAVCLLHMLLENGHTVYVHCNAGVGRSAAAVCGWLQYVMGWNLRKVQYFLMAKRPAVYIDEEALGRAQEDFYQKFGKLRSSICNL