Details from NCBI annotation

Gene Symbol Eps8
Gene Name epidermal growth factor receptor pathway substrate 8, transcript variant X3
Entrez Gene ID 101715552

This gene is present in the GenAge database and has been identified as potentially important to ageing in humans.

Database interlinks

Part of NW_004624752.1 (Scaffold)

For more information consult the page for NW_004624752.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

EPS8 ENSCPOG00000012163 (Guinea pig)

Gene Details

epidermal growth factor receptor pathway substrate 8

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000010936, Guinea pig)

Protein Percentage 86.05%
CDS Percentage 85.95%
Ka/Ks Ratio 0.24397 (Ka = 0.0957, Ks = 0.3924)

EPS8 ENSG00000151491 (Human)

Gene Details

epidermal growth factor receptor pathway substrate 8

External Links

Gene Match (Ensembl Protein ID: ENSP00000281172, Human)

Protein Percentage 91.36%
CDS Percentage 88.77%
Ka/Ks Ratio 0.10457 (Ka = 0.0434, Ks = 0.4154)

Eps8 ENSMUSG00000015766 (Mouse)

Gene Details

epidermal growth factor receptor pathway substrate 8

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000052776, Mouse)

Protein Percentage 87.58%
CDS Percentage 84.21%
Ka/Ks Ratio 0.09825 (Ka = 0.066, Ks = 0.6716)

Eps8 ENSRNOG00000007047 (Rat)

Gene Details

Epidermal growth factor receptor kinase substrate 8

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000009328, Rat)

Protein Percentage 88.44%
CDS Percentage 84.18%
Ka/Ks Ratio 0.08483 (Ka = 0.0602, Ks = 0.7091)

Genome Location

Sequence Coding sequence

Length: 2469 bp    Location: 22250956..22424957   Strand: +
>XM_004845821.1
ATGAATGGACATATTTCTAACCATCCCAGTGGTTTTGGAACGTACCCATCTCAAATGAATGGCTACGGATCATCACCCACCTATTCCCAGAATGACAGAGAACACAGTTCAAAGACAAGTGCAAAGGCCCTTTATGAACAAAGGAAGAATTATGCCCGTGACAGTGTCAGCAGTGTGTCAGATATATCCCAGTACCGAGTTGAACACCTGACTACCTTTGTTCTGGATCGGAAAGATGCTATGATAACAGTTGATGATGGAATAAGGAAGCTGAAATTGCTCGATGCCAAGGGCAAAGTATGGACTCAAGATATGATTCTTCAAGTGGATGACCGAGCCGTGAGCCTGATTGATTTAGAGTCAAAGAATGAATTGGAGAATTTTCCTTTAAACACAATCCAGCACTGCCAAGCTGTAATGCATTCCTGCAACTATGATTCAATTCTTGCCCTGGTGTGCAAAGAGCCGACTCAGAACAAGCCAGATCTTCATCTTTTCCAGTGTGATGAGATTAAGGCAAACCTAATTAGTGAAGATATTGAAAGTGCAGTCAGCGACAGTAAAGGAGGGAAACAGAAGAGGCGGCCAGAGGCCCTGAGGATGATTTCCAAAGCAGACCCTGGCATACCGCCCCCACCCAGAGCCCCTGCCCCCGTGCCTCCGGGGACGGTCACCCAGGTGGACGTGAGAAGTCGCGTGGCAGCCTGGTCTGCGTGGGCAGCTGACCAAGGGGATTTTGAGAAACCAAGGCAGTACCAGGAGCAGGAAGAGACTCCTGAGATGGTGGCAGCCCGGATCGACAGGGATGTGCAAATCTTAAACCATATTTTGGATGACATTGAATTTTTTATCACAAAACTCCAAAAAGCTGCTGAAGCATTTTCTGAGCTTTCTAAAAGGAAGAAAACTAAGAAAGGTAAAAGGAAAGGACCAGGAGAGGGTGTTTTGACGCTGAGAGCAAAACCTCCACCTCCTGACGAGTTTGTCGACTGTTTCCAGAAGTTTAAACATGGATTTAACCTTCTGGCCAAATTGAAATTTCATATCCAGAATCCCAGCGCTTCAGATTTGGTTCATTTTTTGTTTACTCCATTAAATATGGTGGTACAGGCAACAGGAGGTCCTGAAATGGCCAGTTCAGTACTCAGTCCCCTACTGAATAAGGACACAATCGATTTCTTGAATTACACTGTCAGTGCCGATGAGCGGCAGCTGTGGATGTCACTGGGTGAAGCTTGGATGAAAGCCAGAGCAGAGTGGCCAAAAGAACAGTTTATTCCGCCCTACATTCCACGGTTCCGCAACGGCTGGGAGCCCCCAATGCTGAACTTTCTGGGGACACCGAAGGAACAAGACCTGTATCACCTGGCAGAGTCGGTGGCAAACGTGGCAGAGCATCAGCGCAAACAGGACATGAAGAGATTGTCCGCAGAGCCTTCCGGCGTGTCAGAGTACCCCCCGGCTGACGCGTTTGCATTCAGTAACAACATCTACGGGAGAGGGCCGCCTTTGGACCAAGTGGACAGTGTGGCTGCTTTTAAGCCAACTCCTAATCGCCATGGAGAAAGAAATTATGACCCATTGAAAACACAACCCAAGAAATATGCCAAATCCAAGTACGACTTTGTGGCAAGGAATAACAGTGAGCTCTCAGTTCTAAAGGATGATATTTTGGAGATACTTGATGATAGGAAGCAATGGTGGAAAGTTCGAAATGCAAGTGGAGACTCTGGGTTTGTGCCAAATAACATTCTGGACATTGTGAGACCTCCAGAATATGGATTAGGGCGTGCTGATCCACCTTACACACATACCATACAGAAACAAAGGATGGAATACGGCCCAAGGCCAGCTGAGAGCCCTTCTGCCCCATCACCTCCTCCGACACCAGCTCCCATTCCTGCCCCTCTCCCACCTTCAGTACCAGCACCCATTCCTATGTCAAAGGTCCCAGCAAATATCACTCGTCAGAACAGCGGCTCGAGTGACAGCGGTGGCAGTATTGTACGAGATGGCCAGAGACACAAACAGCTTCCAGTGGACCGGCGGAAGTCTCAGATGGAGGAGGTACAGGACGAGCTGGTCCACAGGCTGACCATTGGGCGCAGCGCCGCGCAGAAGAAGCTGCAGGTGCCACGGCAGAACATGCCCGTCATCAACATCACATACGACTCCGCCCCAGAGGAGGTGAAGACCTGGCTGCAGTCGAAGGGGTTCAGCCCTGTGACAGTGAATAGTCTTGGAGTGTTAAACGGTGCACAACTTTTCTCTCTGAACAAAGATGAACTGCGGACGGTGTGCCCTGAAGGGGCCAGAGTGTTCAGCCAAATCACGGTGCAGAAAGCTGCACTGGAGGACAGCAATGGCAGCTCGGAATTGCAAGAAATTATGCGAAGACGACAGGAAAAAATCAGTGCTGCTGCTAGTGATTCAGGAGTGGAATCTTTTGATGAAGGAAGCAGTCACTAA

Related Sequences

XP_004845878.1 Protein

Eps8 PREDICTED: epidermal growth factor receptor kinase substrate 8 isoform X3 [Heterocephalus glaber]

Length: 822 aa      View alignments
>XP_004845878.1
MNGHISNHPSGFGTYPSQMNGYGSSPTYSQNDREHSSKTSAKALYEQRKNYARDSVSSVSDISQYRVEHLTTFVLDRKDAMITVDDGIRKLKLLDAKGKVWTQDMILQVDDRAVSLIDLESKNELENFPLNTIQHCQAVMHSCNYDSILALVCKEPTQNKPDLHLFQCDEIKANLISEDIESAVSDSKGGKQKRRPEALRMISKADPGIPPPPRAPAPVPPGTVTQVDVRSRVAAWSAWAADQGDFEKPRQYQEQEETPEMVAARIDRDVQILNHILDDIEFFITKLQKAAEAFSELSKRKKTKKGKRKGPGEGVLTLRAKPPPPDEFVDCFQKFKHGFNLLAKLKFHIQNPSASDLVHFLFTPLNMVVQATGGPEMASSVLSPLLNKDTIDFLNYTVSADERQLWMSLGEAWMKARAEWPKEQFIPPYIPRFRNGWEPPMLNFLGTPKEQDLYHLAESVANVAEHQRKQDMKRLSAEPSGVSEYPPADAFAFSNNIYGRGPPLDQVDSVAAFKPTPNRHGERNYDPLKTQPKKYAKSKYDFVARNNSELSVLKDDILEILDDRKQWWKVRNASGDSGFVPNNILDIVRPPEYGLGRADPPYTHTIQKQRMEYGPRPAESPSAPSPPPTPAPIPAPLPPSVPAPIPMSKVPANITRQNSGSSDSGGSIVRDGQRHKQLPVDRRKSQMEEVQDELVHRLTIGRSAAQKKLQVPRQNMPVINITYDSAPEEVKTWLQSKGFSPVTVNSLGVLNGAQLFSLNKDELRTVCPEGARVFSQITVQKAALEDSNGSSELQEIMRRRQEKISAAASDSGVESFDEGSSH