Details from NCBI annotation

Gene Symbol Mlc1
Gene Name megalencephalic leukoencephalopathy with subcortical cysts 1, transcript variant X2
Entrez Gene ID 101713212

Database interlinks

Part of NW_004624752.1 (Scaffold)

For more information consult the page for NW_004624752.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

MLC1 ENSCPOG00000025472 (Guinea pig)

Gene Details

megalencephalic leukoencephalopathy with subcortical cysts 1

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000016459, Guinea pig)

Protein Percentage 87.93%
CDS Percentage 87.62%
Ka/Ks Ratio 0.18624 (Ka = 0.0711, Ks = 0.3819)

MLC1 ENSG00000100427 (Human)

Gene Details

megalencephalic leukoencephalopathy with subcortical cysts 1

External Links

Gene Match (Ensembl Protein ID: ENSP00000310375, Human)

Protein Percentage 82.98%
CDS Percentage 82.89%
Ka/Ks Ratio 0.13463 (Ka = 0.0953, Ks = 0.7075)

Mlc1 ENSMUSG00000035805 (Mouse)

Gene Details

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000047667, Mouse)

Protein Percentage 84.82%
CDS Percentage 81.94%
Ka/Ks Ratio 0.09594 (Ka = 0.081, Ks = 0.8446)

Mlc1 ENSRNOG00000032871 (Rat)

Gene Details

megalencephalic leukoencephalopathy with subcortical cysts 1 (Mlc1), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000052732, Rat)

Protein Percentage 84.29%
CDS Percentage 81.15%
Ka/Ks Ratio 0.09101 (Ka = 0.0853, Ks = 0.9372)

Genome Location

Sequence Coding sequence

Length: 1149 bp    Location: 654616..675863   Strand: +
>XM_004845355.1
ATGACTCGAGACGGGCAGTTCAGGGAGGAGATGGGCTACGACCGGATGCCGACCCTGGAGCGGGGTCGGCAGGACATCGGGCAGCAGGATCTAGGCAACTTCAGCGCAGACGCAAAGCCCAAGGACCTCCAGCTGTCGAAGAGGCTGCCCCCGTGCCTCAGCTACAAGACACGGGTCTTCTCCGTGCTGATGGGGAGCTGCCTCCTGGTGACCTCGGGCTTCTCACTGTACCTGGGTAACGTGTTCCCCTCCGAGATGGACTACCTGCGGTGCGCTGCTGCCTCTTGTCTCCCCTCAGCAATTGTGACCTTTGCTGTTTCCAGGAGCAACATCAATGCGATTCCCAACTTTCAGATATTATTTGTTTCCACGTTTGCCATCACCACTACTTGCTTGATCTGGTTTGGATGCAAACTTGTTCTGAACCCATCGGCAATAAACATAAACTTCAACCTCATCCTGCTGCTCCTGTTGGAGCTCCTCATGGCCGCCAATGTCATCATCTCAGCACGCTCGAGCGAGGAGCCCTGCGGGAAGAAGAAGGGCTCCGTCTCCGACAGCACCCATATTTTGGATGAAGTGACATTTCCTGCTCGGGTCCTAAAGTCCTACTCTGTAGTCGAGGTGATTGCTGGCATCTCTGCCGTCCTTGGTGTGGTCATCGCTCTGAACGTGGATGACGCGGTCTCAGGCCCACACCTCTCAGTGACCTTCTTTTGGATCTTGGTGGCTTGTTTTCCGAGTGCCATCGCCAGTCATGTGACAGCAGAGCATCCTAGCAGGTGTCTGGTGGAGGTGTTGCTTGCCCTCAGCAGCCTCACATCCCCATTGCTGTTTACGGCCTCTGGTTACCTGTCGGTCAGTGTGATGACAGTGGTGGAGACTTTCAAAGGCTACCCCCCAGCCATCAGAGCCTACGACGTGCTGCTGCTGCTGCTGCTGCTTGTGCTGCTCCTGCAGGGTGGCCTCAACACGGGCACTGCCGTGCTGTGTGTGAGCTTCAAGGTCAGCACCAGGCTGCAAGGTGCATCCTGGGAGGCCCCAGCCGCCCTGCAGGAGCACCCCACGGGGGAGGTGGCCAGAAGTCCCCGGAAGGAGTTTGACAAGGAGAAAGCCTGGAGAGCCGTCATGGTGCAGATGGCCCAGTGA

Related Sequences

XP_004845412.1 Protein

Mlc1 PREDICTED: membrane protein MLC1 isoform X2 [Heterocephalus glaber]

Length: 382 aa      View alignments
>XP_004845412.1
MTRDGQFREEMGYDRMPTLERGRQDIGQQDLGNFSADAKPKDLQLSKRLPPCLSYKTRVFSVLMGSCLLVTSGFSLYLGNVFPSEMDYLRCAAASCLPSAIVTFAVSRSNINAIPNFQILFVSTFAITTTCLIWFGCKLVLNPSAININFNLILLLLLELLMAANVIISARSSEEPCGKKKGSVSDSTHILDEVTFPARVLKSYSVVEVIAGISAVLGVVIALNVDDAVSGPHLSVTFFWILVACFPSAIASHVTAEHPSRCLVEVLLALSSLTSPLLFTASGYLSVSVMTVVETFKGYPPAIRAYDVLLLLLLLVLLLQGGLNTGTAVLCVSFKVSTRLQGASWEAPAALQEHPTGEVARSPRKEFDKEKAWRAVMVQMAQ