Sequence details NCBI ID: XM_004845156.1 (Coding sequence)   Best Hit

Details from NCBI annotation

Gene Symbol Srd5a1
Gene Name steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1), transcript variant X2
Entrez Gene ID 101714960

Database interlinks

Part of NW_004624751.1 (Scaffold)

For more information consult the page for NW_004624751.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

SRD5A1 ENSCPOG00000008203 (Guinea pig)

Gene Details

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000007377, Guinea pig)

Protein Percentage 83.27%
CDS Percentage 85.03%
Ka/Ks Ratio 0.21306 (Ka = 0.097, Ks = 0.4553)

SRD5A1 ENSG00000145545 (Human)

Gene Details

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)

External Links

Gene Match (Ensembl Protein ID: ENSP00000274192, Human)

Protein Percentage 65.49%
CDS Percentage 73.73%
Ka/Ks Ratio 0.34531 (Ka = 0.2417, Ks = 0.7)

Srd5a1 ENSMUSG00000021594 (Mouse)

Gene Details

steroid 5 alpha-reductase 1

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000089097, Mouse)

Protein Percentage 72.16%
CDS Percentage 74.12%
Ka/Ks Ratio 0.16993 (Ka = 0.1844, Ks = 1.0854)

Srd5a1 ENSRNOG00000017601 (Rat)

Gene Details

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) (Srd5a1), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000023659, Rat)

Protein Percentage 71.37%
CDS Percentage 74.77%
Ka/Ks Ratio 0.18802 (Ka = 0.1886, Ks = 1.0031)

Genome Location

Sequence Coding sequence

Length: 768 bp    Location: 4309495..4335334   Strand: +
Raw sequence   
>XM_004845156.1
ATGGAGCCAGAGGAGCTGCGCCTGCTGGACGCGTTCGCCTACCTGATGATGCTCACGGGCTGCGTATGCTTTGCCCTGCTCCTGCGCCTCTCGTCGCCCTACGGCCGCTACGCGTCACAGTGGCCCGGTCCGCGGGTGCCCGCGCGTGTCGCCTGGGCCCTGCAGGAGCTGCCGGCGCTGGCCTGGCCGCTGCTCGAGTGCACCTGCGCGTCCCCCCAGCGCCTCGACCGCCTTCCCAACCGCGTGCTGCTGGCCATGTACCTCGTCCACTATGTGCACAGGTCCCTGATCTTCCCCTTCCTGATCCGAGGAGGAAAGCCGATGCCTCTTGTCACCTGTGTGTTAGCCTTCCTGTTCTGTACCTGTAATGGCTACTTGCAGACCAGGTACCTGAGCTGGTATGCGGTGTACGCCGAGGACTGGGTGACCCAGCCCTGCTTTCTAGCTGGTTTTGCCTTGTGGTTAACGGGCATGCTGATAAACATCCAGTCAGATCACATCCTGAGGAACCTCCGAAAACCAGAGGAGACAGGATACAAAATACCAAGGGGAGGCTTGTTCGAATACATAACTGCGGCCAACTACCTTGGGGAAGTTGTGGAGTGGTGCGGCTTTGCACTGGCCAGCTGCTCTCTGCAGAGTGGGGCTTTTGCGCTATTCACATTGACCGTTTTACTCCCCAGAGCAAAACAGCATCACCGGTGGTACCTTGAGAAGTTTGAAGATTATCCAAAGTCTCGGAAAATTTTAATTCCATTTTTGTATTAA

Related Sequences

XP_004845213.1 Protein

Srd5a1 PREDICTED: 3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform X2 [Heterocephalus glaber]

Length: 255 aa      View alignments
>XP_004845213.1
MEPEELRLLDAFAYLMMLTGCVCFALLLRLSSPYGRYASQWPGPRVPARVAWALQELPALAWPLLECTCASPQRLDRLPNRVLLAMYLVHYVHRSLIFPFLIRGGKPMPLVTCVLAFLFCTCNGYLQTRYLSWYAVYAEDWVTQPCFLAGFALWLTGMLINIQSDHILRNLRKPEETGYKIPRGGLFEYITAANYLGEVVEWCGFALASCSLQSGAFALFTLTVLLPRAKQHHRWYLEKFEDYPKSRKILIPFLY