Sequence detailsNCBI ID: XM_004844754.1 (Coding sequence)  Best Hit

Details from NCBI annotation

Gene Symbol Mthfd2
Gene Name methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
Entrez Gene ID 101705997

Database interlinks

Part of NW_004624749.1 (SequenceType object (1))

For more information consult the page for NW_004624749.1 (SequenceType object (1))

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

ENSCPOG00000019778 (Guinea pig)

Gene Details

Uncharacterized protein

External Links

Gene Match(Ensembl Protein ID:ENSCPOP00000018875, Guinea pig)

Protein Percentage 58.11%
CDS Percentage 72.7%
Ka/Ks Ratio 0.70013 (Ka = 0.3285, Ks = 0.4692)

MTHFD2ENSG00000065911 (Human)

Gene Details

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

External Links

Gene Match(Ensembl Protein ID:ENSP00000377617, Human)

Protein Percentage 94.16%
CDS Percentage 89.94%
Ka/Ks Ratio 0.09318 (Ka = 0.0326, Ks = 0.3502)

Mthfd2ENSMUSG00000005667 (Mouse)

Gene Details

methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase

External Links

Gene Match(Ensembl Protein ID:ENSMUSP00000005810, Mouse)

Protein Percentage 91.56%
CDS Percentage 84.42%
Ka/Ks Ratio 0.06511 (Ka = 0.047, Ks = 0.7223)

Mthfd2ENSRNOG00000010833 (Rat)

Gene Details

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (Mthfd2), mRNA

External Links

Gene Match(Ensembl Protein ID:ENSRNOP00000014603, Rat)

Protein Percentage 90.55%
CDS Percentage 84.04%
Ka/Ks Ratio 0.07839 (Ka = 0.0552, Ks = 0.7038)

Genome Location

Sequence SequenceType object (2)

Length: 933 bp    Location: 29276708..29264510   Strand: -
Raw sequence   
>XM_004844754.1
ATGACTATGGCTGCAACTTCTCTCCTGTCTGCTTTGGCCGCCCGGCTACTCAGGCCGACGCACAGCTGCCATCTTCGCCATCGCCTCTTCCATCTCGCCGCAGTTCGAAATGAAGCTGTTGTCATTTCTGGAAGGAAACTGGCCCAGCAGATCAAGCAGGAGGTTCGGCAGGAGGTGGAAGAGTGGGTGGCTGAAGGCAACAAGCGGCCACACCTGAGCGTGGTTCTGGTTGGCGAGAATCCTGCAAGCCACTCATATGTCCTCAACAAAACCAGGGCAGCTGCAGATGTGGGAATCAACAGCGAGACGATTGTGAAACCAGCTTCAATTTCAGAAGAAGAGCTGTTGAATTTGATCAATAAACTCAATAATGATGAAAACGTAGATGGCCTCCTTGTTCAGCTGCCTCTCCCAGAGCATATTGATGAGAGAAGGATCTGCAATGCTGTTTCTCCAGACAAGGACGTTGATGGCTTTCATGTAATTAATGTGGGGCGAATGTGTTTGGACCAGTATTCCATGTTGCCAGCTACCCCGTGGGGTGTATGGGAAATAATTAAGCGAACAGGCATTCCCACCCTAGGAAAGAATGTAGTTGTGGCTGGAAGATCAAAAAATGTTGGAATGCCCATTGCAATGTTACTGCACACAGATGGGGCACATGAACGTCCTGGGGGTGATGCCACTGTTACAATATCTCATCGCTACACTCCTAAAGAACAGCTGAAGAAACACACTATTCTTGCGGATATTGTAGTATCTGCTGCAGAAGTCAAGAAGAAAGCCAGTTACATCACTCCAGTCCCTGGGGGCGTTGGTCCCATGACAGTGGCAATGCTAATGAAGAATACCATTATTGCTGCAAAAAAAGTGTTAAGGCCTGAAGAGAGGGAAGTGCTGAAGCCTAAAGAGCTTGGAGTAGCCACCAATTAA

Related Sequences

XP_004844811.1 SequenceType object (4)

Mthfd2 PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Heterocephalus glaber]

Length: 310 aa      
>XP_004844811.1
MTMAATSLLSALAARLLRPTHSCHLRHRLFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVAEGNKRPHLSVVLVGENPASHSYVLNKTRAAADVGINSETIVKPASISEEELLNLINKLNNDENVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVVSAAEVKKKASYITPVPGGVGPMTVAMLMKNTIIAAKKVLRPEEREVLKPKELGVATN