Details from NCBI annotation

Gene Symbol Ptpn11
Gene Name protein tyrosine phosphatase, non-receptor type 11, transcript variant X2
Entrez Gene ID 101701336

This gene is present in the GenAge database and has been identified as potentially important to ageing in humans.

Database interlinks

Part of NW_004624747.1 (Scaffold)

For more information consult the page for NW_004624747.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

PTPN11 ENSCPOG00000013527 (Guinea pig)

Gene Details

protein tyrosine phosphatase, non-receptor type 11

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000012179, Guinea pig)

Protein Percentage 97.62%
CDS Percentage 93.65%
Ka/Ks Ratio 0.04568 (Ka = 0.0124, Ks = 0.2705)

PTPN11 ENSG00000179295 (Human)

Gene Details

protein tyrosine phosphatase, non-receptor type 11

External Links

Gene Match (Ensembl Protein ID: ENSP00000340944, Human)

Protein Percentage 99.66%
CDS Percentage 91.68%
Ka/Ks Ratio 0.00367 (Ka = 0.0015, Ks = 0.4226)

Ptpn11 ENSMUSG00000043733 (Mouse)

Gene Details

protein tyrosine phosphatase, non-receptor type 11

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000058757, Mouse)

Protein Percentage 99.16%
CDS Percentage 88.25%
Ka/Ks Ratio 0.00539 (Ka = 0.0039, Ks = 0.7207)

Ptpn11 ENSRNOG00000030124 (Rat)

Gene Details

protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 2, mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000041842, Rat)

Protein Percentage 98.65%
CDS Percentage 88.59%
Ka/Ks Ratio 0.00916 (Ka = 0.0062, Ks = 0.6759)

Genome Location

Sequence Coding sequence

Length: 1782 bp    Location: 19813631..19725381   Strand: -
>XM_004843765.1
ATGACATCGCGGAGATGGTTTCACCCAAACATCACTGGAGTGGAGGCAGAAAATCTACTGTTGACCAGAGGAGTTGATGGCAGTTTTTTGGCGAGGCCCAGTAAAAGTAACCCCGGAGACTTCACACTTTCAGTTAGAAGAAATGGAGCTGTCACCCACATCAAGATTCAGAACACGGGTGACTACTATGATCTGTACGGAGGGGAGAAGTTTGCCACTTTGGCTGAGCTGGTCCAGTATTACATGGAACATCATGGGCAGCTGAAAGAGAAGAATGGAGATGTTATCGAGCTCAAATATCCACTGAACTGTGCAGATCCTACCTCTGAAAGGTGGTTTCATGGTCACCTCTCTGGGAAAGAAGCAGAGAAATTACTAACCGAGAAGGGAAAACATGGTAGCTTTCTTGTCCGAGAGAGCCAGAGCCACCCTGGAGATTTTGTTCTCTCTGTCCGCACGGGTGATGACAAAGGGGAGAGCAATGATGGCAAATCTAAAGTGACCCACGTCATGATCCGCTGCCAGGAACTGAAATATGATGTTGGTGGAGGAGAACGGTTTGATTCCTTGACAGATCTGGTGGAGCATTACAAGAAGAATCCGATGGTAGAAACATTGGGCACAGTACTCCAACTCAAGCAGCCCCTCAACACAACTCGTATCAATGCTGCTGAAATTGAAAGTCGGGTTCGAGAATTGAGCAAATTAGCCGAGACCACAGATAAAGTCAAACAAGGCTTCTGGGAAGAATTTGAGACACTACAACAACAGGAGTGCAAACTTCTCTACAGCCGAAAAGAGGGCCAGAGGCAAGAAAATAAAAACAAAAATAGATACAAAAATATCCTGCCCTTTGATCACACCAGGGTGGTCCTCCACGACGGTGACCCCAACGAGCCCGTGTCTGACTACATCAACGCAAACATCATCATGCCTGAATTCGAAACCAAGTGCAACAATTCAAAGCCCAAAAAGAGCTACATTGCCACACAAGGCTGCCTGCAAAACACGGTGAACGACTTTTGGCGAATGGTGTTCCAGGAGAATTCTCGAGTGATCGTCATGACGACAAAAGAAGTGGAGCGAGGAAAGAGCAAATGTGTCAAGTACTGGCCGGATGAGTACGCTCTCAAAGAGTATGGGGTCATGCGCGTCAGGAATGTCAAAGAGAGTGCCGCACATGACTACACGCTAAGAGAACTGAAACTCTCGAAGGTTGGACAAGGGAATACGGAGAGAACGGTCTGGCAATACCACTTTCGGACCTGGCCGGACCACGGCGTGCCCAGTGACCCCGGGGGCGTGTTAGACTTCCTGGAGGAGGTCCACCACAAGCAGGAGAGCATCATGGACGCGGGCCCTGTCGTGGTGCACTGCAGTGCTGGAATTGGCCGGACAGGAACATTCATTGTGATTGATATCCTTATTGACATCATCAGAGAGAAAGGTGTCGACTGCGACATCGATGTTCCCAAAACCATTCAAATGGTACGGTCTCAGAGGTCAGGGATGGTCCAGACAGAAGCACAGTACCGGTTTATCTACATGGCTGTCCAGCATTATATTGAAACACTACAGCGAAGGATTGAAGAAGAGCAGAAAAGCAAGAGGAAAGGGCACGAATATACCAATATTAAGTATTCCCTAGCGGACCAGGCAAGTGGCGATCAGAGTCCCCTCCCACCGTGTACGCCAACACCACCCTGTGCAGAAATGAGAGAAGACAATGCCAGAGTCTATGAGAACGTGGGCTTGATGCAGCAGCAGAAGAGCTTCAGATGA

Related Sequences

XP_004843822.1 Protein

Ptpn11 PREDICTED: tyrosine-protein phosphatase non-receptor type 11 isoform X2 [Heterocephalus glaber]

Length: 593 aa      View alignments
>XP_004843822.1
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQASGDQSPLPPCTPTPPCAEMREDNARVYENVGLMQQQKSFR