Details from NCBI annotation

Gene Symbol Chek2
Gene Name checkpoint kinase 2, transcript variant X3
Entrez Gene ID 101721212

This gene is present in the GenAge database and has been identified as potentially important to ageing in humans.

Database interlinks

Part of NW_004624747.1 (Scaffold)

For more information consult the page for NW_004624747.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

CHEK2 ENSCPOG00000006172 (Guinea pig)

Gene Details

checkpoint kinase 2

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000005566, Guinea pig)

Protein Percentage 94.63%
CDS Percentage 95.45%
Ka/Ks Ratio 0.26371 (Ka = 0.0278, Ks = 0.1054)

CHEK2 ENSG00000183765 (Human)

Gene Details

checkpoint kinase 2

External Links

Gene Match (Ensembl Protein ID: ENSP00000372023, Human)

Protein Percentage 88.21%
CDS Percentage 89.33%
Ka/Ks Ratio 0.22826 (Ka = 0.0657, Ks = 0.288)

Chek2 ENSMUSG00000029521 (Mouse)

Gene Details

checkpoint kinase 2

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000066679, Mouse)

Protein Percentage 82.59%
CDS Percentage 83.11%
Ka/Ks Ratio 0.16566 (Ka = 0.0967, Ks = 0.5835)

Chek2 ENSRNOG00000037509 (Rat)

Gene Details

checkpoint kinase 2 (Chek2), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000053643, Rat)

Protein Percentage 82.95%
CDS Percentage 82.75%
Ka/Ks Ratio 0.14346 (Ka = 0.0911, Ks = 0.6348)

Genome Location

Sequence Coding sequence

Length: 1596 bp    Location: 5070638..5035051   Strand: -
>XM_004843364.1
ATGTCTCGAGAGTCAAATGCAGAGAGTCAACAGTCCTACAGCAACACCTCCTCACAGGCCCATGGCAGTGGTACCAGTTCACAGACCCAAGGTGGCTTCAACCAGTCACAAGGCAGTTTGTCCCAGTCCCCTGGGTTTGCTTCACAGTCTCACGGGTCTTTGTCACAGTCCCAAGGCACATCTAGCTCCTCCGCTGGCACAGTGCCCACCTCTAGCCAGTCCTCTCAGTCCAGCTCCGGGACGCTGAGCTCCTTAGAGACCGTGTCCACTCAGGAACTCTGTTCTATTCCTGAGGACCAAGAACCTGAGGAACCTGTTCCTGCCCCTTGGGCTCGGCTATGGGCTCTTCAGGAAGGATTCTCCAATTTTGAGTGTGTTAATGACAACTACTGGTTTGGGAGGGATAAAAGCTGTGACTATTGCTTTGATGAACCCCTGCTAAAAAGAACAGATAAATACAGGACATATAGCAAGAAACACTTTCGGATTTTCAGGGAAATGGGTCCTAAAAACTCTTACATCGCATACATAGAAGATCACAGTGGGAATGGAACCTTTGTAAATACAGAGCTTGTAGGGAGAGGAAAACATCGTCCTTTGAGTAACAATTCTGAAATTGCACTTTCATTATGTAGAAATAAAGTTTTTGTATTTTTTGATCTGACTGTAGATGATCAGTCAGTTTATCCCAAGCAATTAAGAGATGAATACATCATATCAAAAACTCTTGGAAGTGGTGCTTGTGGAGAGGTAAAGCTGGCTTTTGAGAGGAAAACATGTAAGAAAGTAGCCATAAAGATCATCAGCAAAAGGAAATTTGCTATTGGTTCTTTGAAAGAGTTAGACTCAGCTCTTAATGTTGAAACTGAAATAGAAATTTTGAAAAAACTAAACCACCCTTGTATCATCAAGATTAAAAACTTTTTTGATGCAGAAGATTATTACATTGTTTTGGAATTGATGGAAGGGGGAGAGCTGTTTGACAGGGTGGTGGGGCATAAACATCTGAAAGAAGCTACCTGCAAGCTCTATTTTTACCAGATGCTTTTGGCTGTCCAGATTACTGATTTTGGGCAGTCCAAGATTTTGGGGGAGACCTCTCTCATGAGAACTTTATGTGGTACCCCCACTTACTTGGCTCCTGAGGTTCTTCTTTCTATTGGGACTACGGGGTATAACCGAGCTGTGGACTGCTGGAGTTTAGGAGTTATTCTTTTTATCTGCCTTAGTGGGTATCCACCTTTCTCTGAGCATAAGACTCAAGTCTCACTGAAGGATCAGATCACCAGTGGAAAGTACACCTTCATTCCTGAAGTCTGGGCAGATGTCTCAGAGAAGGCTCTGGACCTTGTCAAGAAGTTGTTGGTTGTGGATCCCAAGGCACGGTTTACAACTGAAGAAGCCTTAGGTCACCCATGGCTTCAGGATGAGGACATGAAGAGAAAGTTTCAGAATCTACTGGCTGAGGAAAATAAGCTGTTGGCTCTACCCCAGGTCTCACCCCAGCCTTCCACTAGTCGAAAGCGGCCTCTCAAAGCAGAAGCTGAGGACACCAAGACCACAAAGCGTCCAGCTGTGTGTGCTGCTGTGTCATGA

Related Sequences

XP_004843421.1 Protein

Chek2 PREDICTED: serine/threonine-protein kinase Chk2 isoform X3 [Heterocephalus glaber]

Length: 531 aa      View alignments
>XP_004843421.1
MSRESNAESQQSYSNTSSQAHGSGTSSQTQGGFNQSQGSLSQSPGFASQSHGSLSQSQGTSSSSAGTVPTSSQSSQSSSGTLSSLETVSTQELCSIPEDQEPEEPVPAPWARLWALQEGFSNFECVNDNYWFGRDKSCDYCFDEPLLKRTDKYRTYSKKHFRIFREMGPKNSYIAYIEDHSGNGTFVNTELVGRGKHRPLSNNSEIALSLCRNKVFVFFDLTVDDQSVYPKQLRDEYIISKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSLKELDSALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDRVVGHKHLKEATCKLYFYQMLLAVQITDFGQSKILGETSLMRTLCGTPTYLAPEVLLSIGTTGYNRAVDCWSLGVILFICLSGYPPFSEHKTQVSLKDQITSGKYTFIPEVWADVSEKALDLVKKLLVVDPKARFTTEEALGHPWLQDEDMKRKFQNLLAEENKLLALPQVSPQPSTSRKRPLKAEAEDTKTTKRPAVCAAVS