Details from NCBI annotation

Gene Symbol Hic2
Gene Name hypermethylated in cancer 2, transcript variant X4
Entrez Gene ID 101700508

Database interlinks

Part of NW_004624747.1 (Scaffold)

For more information consult the page for NW_004624747.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

HIC2 ENSCPOG00000001134 (Guinea pig)

Gene Details

hypermethylated in cancer 2

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000001024, Guinea pig)

Protein Percentage 93.69%
CDS Percentage 92.07%
Ka/Ks Ratio 0.11277 (Ka = 0.032, Ks = 0.2841)

HIC2 ENSG00000169635 (Human)

Gene Details

hypermethylated in cancer 2

External Links

Gene Match (Ensembl Protein ID: ENSP00000387757, Human)

Protein Percentage 90.89%
CDS Percentage 87.59%
Ka/Ks Ratio 0.06626 (Ka = 0.0458, Ks = 0.6918)

Hic2 ENSMUSG00000050240 (Mouse)

Gene Details

hypermethylated in cancer 2

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000087656, Mouse)

Protein Percentage 86.87%
CDS Percentage 84.22%
Ka/Ks Ratio 0.10049 (Ka = 0.071, Ks = 0.7065)

Hic2 ENSRNOG00000001863 (Rat)

Gene Details

hypermethylated in cancer 2 (Hic2), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000002545, Rat)

Protein Percentage 87.52%
CDS Percentage 84.87%
Ka/Ks Ratio 0.09758 (Ka = 0.0673, Ks = 0.6899)

Genome Location

Sequence Coding sequence

Length: 1857 bp    Location: 1094983..1067912   Strand: -
>XM_004843306.1
ATGGTTTCTGGGCCCCTGGCACTCCGGTGGTACGCGTGGGCAGGGCGTGGGGACATGGGGCCCGACATGGAGCTGCCCAGCCACTCAAAGCAGCTCCTGCTGCAGCTGAACCAGCAGAGGACCAAGGGCTTCCTATGTGATGTCATCATCATGGTGGAGAACTCCATTTTCCGGGCCCACAAGAACGTCTTGGCTGCCAGCAGCATCTACTTCAAGTCCCTGGTCCTGCACGACAACCTCATCAACCTGGACACAGACATGGTCAGCTCCACGGTGTTCCAGCAGATCTTGGACTTCATCTACACCGGCAAGCTGCTGCCCAGCAACTGTCCTGCTGAGCCCAACTTCAGCACTCTCCTCACTGCTGCCAGCTACCTCCAGCTGCCTGAGTTGGCAGCCCTCTGCCGCCGCAAACTCAAGCGGGCTGGTAAGCCCTTTGGCTCAGGACGGGTGGGAGCCACCAGCATGGGGCGGCCACCCCGAAGCCAGCGACTGTCCACAACCTCTGTCATCCAGGCTCGGTATCCAGGGCTCGTGGATGGGCGCAAGGGGGCCCATGCACCCCAGGAGCTTCCCCCAGCCAAAGGCTCAGATGACGAGCTCTTCCTTGGTGGCTCTACCCAGGAGAGCACGCACAGCCTGGGCCAGGGGGTCTGTCCAGCCAGTGGGGAGATGGGCCTGGGGGGTTGCGGTGGCAGCACCAACGGGAGCAGTGGGGGCTGTGAGCAAGAGCTGGGCCTGGACCTATCCAAGAAGAGCCCACCCCTGCCTGCTGCCACCCCTGGGCCCCACCTCACGCCTGATGACCCGGCCCGGCTGAGTGACAGCCAGGAGGGCTCACCCCCCTTGTCCGCTGCCCTGCCTGTTGCCAACAGTGCCTCTTACACTGAGCTGGGTGGCACCCCTGATGAGCCTATGGATTTGGATGGAGCCGAAGACAACCACCTGAGCTTGCTGGAGGGGCCAGGCGGGCAGCCTCGGAAGAGCCTCCGGCACTCGGCCCGGAAGAAGGAATGGAGCAAGAAGGAGCCTGTGGCTGGCTCCCCTTTTGAGCGGAGAGAAGTTGGGCCCAAGGGCCCCTGCTCTGGAGAAGAGGGCGAGGGGCTTGGGGACAGGGTTCCCAATGGCATCTTGGCTGCCAGTGTTGGTGGGGGTGGCCCCAGTGTGCCCTATGGGGAGCCTCCATATCCCTGCAAAGAAGAAGAGGAAAACGGCAAGGACGGGAGCGAGGACAGTGGGCAAAGTGGGAGTGAGGGGGGCAGTGGCCATGCTGGTGCTCACTACATGTATCGGCAGGAGGGCTATGAGACCGTGTCATACGGGGACAACCTGTATGTGTGCATCCCCTGCGCCAAAGGTTTCCCCAGCTCTGAGCAGCTCAATGCCCATGTGGAGACGCACACGGAAGAAGAGTTGTTCATCAAGGAGGAGGGAGCCTATGAGACAGCAAGCTGGGGTGCTAAGGAAGAGGCTGAGGACCTATCTGCGCCCAGCGCAGCATACACAGCAGAGGCTCGGCCCTTCAAGTGCTCGATCTGTGAGAAGACCTACAAGGACCCAGCCACTCTGAGGCAGCACGAGAAGTCGCACTTGCTGACGCGGCCCTATCCCTGTGAAGTCTGCGGCAAGATGTTCACACAGCGTGGCACCATGACACGCCACAAGCGGAGCCACATGGGCCTGAAGCCATTTGCCTGCAATGAATGTGGCATGCGCTTCACCCGCCAGTACCGCCTCACCGAGCACATGCGTGTACACTCAGGCGAGAAGCCTTATGAATGCCACCTCTGTGGGGGCAAGTTCACCCAGCAGCGTAACCTGATCAGCCACCTGCGCATGCACACCTCCCCCTCCTAG

Related Sequences

XP_004843363.1 Protein

Hic2 PREDICTED: hypermethylated in cancer 2 protein-like isoform X4 [Heterocephalus glaber]

Length: 618 aa      View alignments
>XP_004843363.1
MVSGPLALRWYAWAGRGDMGPDMELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLHDNLINLDTDMVSSTVFQQILDFIYTGKLLPSNCPAEPNFSTLLTAASYLQLPELAALCRRKLKRAGKPFGSGRVGATSMGRPPRSQRLSTTSVIQARYPGLVDGRKGAHAPQELPPAKGSDDELFLGGSTQESTHSLGQGVCPASGEMGLGGCGGSTNGSSGGCEQELGLDLSKKSPPLPAATPGPHLTPDDPARLSDSQEGSPPLSAALPVANSASYTELGGTPDEPMDLDGAEDNHLSLLEGPGGQPRKSLRHSARKKEWSKKEPVAGSPFERREVGPKGPCSGEEGEGLGDRVPNGILAASVGGGGPSVPYGEPPYPCKEEEENGKDGSEDSGQSGSEGGSGHAGAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEELFIKEEGAYETASWGAKEEAEDLSAPSAAYTAEARPFKCSICEKTYKDPATLRQHEKSHLLTRPYPCEVCGKMFTQRGTMTRHKRSHMGLKPFACNECGMRFTRQYRLTEHMRVHSGEKPYECHLCGGKFTQQRNLISHLRMHTSPS