Sequence details NCBI ID: XM_004841237.1 (Coding sequence)   Best Hit

Details from NCBI annotation

Gene Symbol Gclm
Gene Name glutamate-cysteine ligase, modifier subunit
Entrez Gene ID 101703324

This gene is present in the GenAge database and has been identified as potentially important to ageing in humans.

Database interlinks

Part of NW_004624742.1 (Scaffold)

For more information consult the page for NW_004624742.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

GCLM ENSCPOG00000014054 (Guinea pig)

Gene Details

glutamate-cysteine ligase, modifier subunit

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000012657, Guinea pig)

Protein Percentage 87.15%
CDS Percentage 88.89%
Ka/Ks Ratio 0.44741 (Ka = 0.0953, Ks = 0.2129)

GCLM ENSG00000023909 (Human)

Gene Details

glutamate-cysteine ligase, modifier subunit

External Links

Gene Match (Ensembl Protein ID: ENSP00000359258, Human)

Protein Percentage 95.99%
CDS Percentage 94.16%
Ka/Ks Ratio 0.14615 (Ka = 0.0228, Ks = 0.156)

Gclm ENSMUSG00000028124 (Mouse)

Gene Details

glutamate-cysteine ligase, modifier subunit

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000029769, Mouse)

Protein Percentage 95.99%
CDS Percentage 91.36%
Ka/Ks Ratio 0.06498 (Ka = 0.0201, Ks = 0.3091)

Gclm ENSRNOG00000013409 (Rat)

Gene Details

glutamate cysteine ligase, modifier subunit (Gclm), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000018343, Rat)

Protein Percentage 96.35%
CDS Percentage 91.97%
Ka/Ks Ratio 0.06059 (Ka = 0.0178, Ks = 0.2941)

Genome Location

Sequence Coding sequence

Length: 825 bp    Location: 3713629..3744028   Strand: +
Raw sequence   
>XM_004841237.1
ATGGGCACCAACAGCCGCGCGGCCGGGGCGCTCCTGGCGCGGGCCAGCACCCTACACCTGCAGACCGGGAACCTGCTAAACTGGGGCCGCCTGCGGAAGAAGTGCCCGTCCACGCACAGCGAGGAGCTTCGAGATTGTATCCAAAAGACCTTGAATGAGTGGAGTTCTCAAATCAGCCCAGATTTGGTCAAGGAGTTTCCAGATGTCTTGGAGTGTACTGTATCTTATGCAATAGAGAAGATAAACCCTGATGAAAGAGAAGAAATGAAAGTTTCTGCAAAACTGTTCATTGTAGGATCAAATTCTTCATCATCAACTAGAAATGCAGTTGACATGGCCTGTTCTGTCCTTGGAGTTGCACAGCTGGATTCTGTGATCATTGCTTCACCTCCTATTGAAGATGGAGTGAATCTTTCCTTGGAGCATTTACAGCCTTACTGGGAGGAATTAGAAAACTTAGTCCAAAGCAAGAAAATTGTTGCTATAGGTACCTCTGACCTAGACAAAACACAGTTGGAGCAGCTGTATCAGTGGGCACAGGTAAAACCAAATAGTAACCAAGTTAATCTTGCCTCCTGCTGTGTGATGCCACCTGATTTGACTGCATTTGCTAAACAGTTTGACATACAGCTGTTGACTCATAATGATCCAAAAGAACTGCTTTCTGAAGCAAGTTTCCAAGAAGCTCTTCAGGAAACCATCCCTGACATTCAAGCACACGAATGGGTACCACTGTGGCTGCTGAGGTACTCGGTCATTGTGAAAAGTAGAGGAATCATCAAATCGAAAGGCTACATTTTGCAAGCCAAAAGAAGGGGTTCTTAA

Related Sequences

XP_004841294.1 Protein

Gclm PREDICTED: glutamate--cysteine ligase regulatory subunit [Heterocephalus glaber]

Length: 274 aa      View alignments
>XP_004841294.1
MGTNSRAAGALLARASTLHLQTGNLLNWGRLRKKCPSTHSEELRDCIQKTLNEWSSQISPDLVKEFPDVLECTVSYAIEKINPDEREEMKVSAKLFIVGSNSSSSTRNAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQETIPDIQAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS