Details from NCBI annotation

Gene Symbol Hecw1
Gene Name HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1, transcript variant X3
Entrez Gene ID 101701199

Database interlinks

Part of NW_004624740.1 (Scaffold)

For more information consult the page for NW_004624740.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

HECW1 ENSCPOG00000000176 (Guinea pig)

Gene Details

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000000153, Guinea pig)

Protein Percentage 95.82%
CDS Percentage 92.61%
Ka/Ks Ratio 0.07659 (Ka = 0.0215, Ks = 0.2802)

HECW1 ENSG00000002746 (Human)

Gene Details

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

External Links

Gene Match (Ensembl Protein ID: ENSP00000379228, Human)

Protein Percentage 91.32%
CDS Percentage 88.66%
Ka/Ks Ratio 0.09999 (Ka = 0.0456, Ks = 0.4558)

Hecw1 ENSMUSG00000021301 (Mouse)

Gene Details

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000106145, Mouse)

Protein Percentage 87.66%
CDS Percentage 83.7%
Ka/Ks Ratio 0.09459 (Ka = 0.0675, Ks = 0.714)

Hecw1 ENSRNOG00000016046 (Rat)

Gene Details

HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 (Hecw1), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000021703, Rat)

Protein Percentage 87.08%
CDS Percentage 83.08%
Ka/Ks Ratio 0.09934 (Ka = 0.0736, Ks = 0.7405)

Genome Location

Sequence Coding sequence

Length: 4752 bp    Location: 18075074..17673270   Strand: -
>XM_004840244.1
ATGGCGTCTCCATCTCGAAACTCCCAGAACCGGCGCCGGTGCAAGGAGCCACTCCGCTACAGCTACAACCCTGACCAGTTCCACAACATGGACATCAGGGGCGGCCCCCACGATGGTGTCACCATACCCCGCTCCACCAGTGACACTGACCTGGTCACCTCGGACAGCCGCTCCACGCTCATGGTCAGCAGTTCCTACTATTCTATAGGGCACTCGCAGGACCTGGTGATCCACTGGGACATCAAGGAGGAGGTGGACGCAGGGGACTGGATTGGCATGTACCTCATAGATGAAGTCTTGTCTGAAAACTTTTTGGACTATAAGAACCGTGGAGTCAATGGTTCTCATCGGGGACAGATCATCTGGAAGATTGATGCCAGCTCTTATTTTGTGGAACCTGAAACTAAGATCTGCTTCAAATACTACCATGGAGTGAGTGGAGCCTTGCGAGCCACCACCCCCAGTGTCACGGTCAAAAACTCAGCGGCTCCTATTTTCAAAAGCATTGGCTCAGATGAGACCACCCAAGGGCAAGGAAGTCGGAGACTGATCAGCTTTTCTCTCTCAGATTTCCAGGCCATGGGGTTGAAGAAAGGGATGTTTTTCAACCCAGACCCATATCTGAAGATTTCCATCCAGCCTGGGAAGCACAGCATCTTCCCTGCCCTCCCTCATCACGGGCAGGAGAGGAGATCCAAGATCATAGGCAACACCGTGAACCCCATCTGGCAGGCGGAGCAATTCAGTTTTGTGTCCTTGCCCACTGATGTGCTAGAAATTGAGGTGAAGGACAAGTTTGCCAAGAGCCGCCCTATCATCAAGCGCTTCCTGGGAAAGCTGTCGATGCCTGTCCAGAGACTCCTGGAGAGACACGCCATAGGGGATAGGGTTGTCAGCTACACACTTGGCCGAAGGCTTCCAACAGATCATGTGAGTGGACAACTGCAATTCCGATTTGAGATCACTTCCTCCATCCACCCAGCAGATGATGAGGAGATTTCACTGAGCACTGAGCCTGAGTCCGCAGAAACTCAGAGCAGCCTCATGAACAGCCTGGTGGGAAGCAGCCGCGTAGAACCTCCAGATGATGTTCCCAATCCCTGCGAGATCTTGAAGGCAGATCCCTTGAGTGAGGACAACGAGATGGACGGTGCAGGAAACCAGAGCCTGGAGCCTGCAGGGCCAGTGGAAGATGTGTCCTGCATCATGGAGGCAGGAGACCAGGGCAAGGCCTTTGAAGAACCCGAGGGGGCTGGGGAGCCACAGGACACCCAGCCCACCCTGAGTGCAGAGGAACTGGCCGAAGGGCTTGGCCTGGATGAGGAGGCACCACCATCGCTGCTGCTGGAGGATGGCGATGCTCTCGCCAACGAGGAGGAGCTGGGGCAAGAGGAAGCAGCTCCCGGGAGCGGGGCAGGAAGGGAAGAGGAGGAAGAAGAGGCGGAGAAGCAGGAGCAGGTGGAGGAGGAGGAGGTGGAGATGGAAGAGGGCGAGGCTTCCAACCCGGAGCAGGGCGAGCGTGCCTTGCAGCTGCGGGCCTTGGCCAAGAGACGAAGCCGGCCATGCTCACTGCCGGTGTCCGAGCTGGAGACTGTGATTGCGGCGGCCTGCGCAGACCCCGAGACACCGCGCACGCACTACATACGCATCCACGCGCTGCTGCACAGCCTGCCGTGCGCGCGCGAAGAGGGCGGCGCTGACGAGGAGCCCACGCTGCGCGACGCCTCAGACAAGGACGCGCTCAGCGAGGAGGCCGACACGCTGGCCGCCGACCCACCCGCGCTGGACGAGGACGCAGCCGAGCCCCAGGGTGGCCTTCCAGGCGTGGGGACCCCCGGCCACCCCGAGGGCCTGCTCCCGGGCCCCGAGGGCGATGCGCATCCTAGCACGGGGAGTGAGAGCGACTCCAGCCCGAGGCCGGGTGGCGAGCACAGCTGCGAGGGCTGCGATGCCTCGTGCTGCAGCCCCTCGTGCTACAGCTCCTCCTGCTACAGCACGTCGTGCTACAGCTCCTCGTGCTACAGCGCCTCCTGCCACAGCCCCTCCTGCTACAATGGTGGCAGCCGCTTCGCCAGCCACACGCGCTTCTCCTCGGTGGACAGCGCCAAGGTCTCCGAGAGCACCGTCTTCTCCTCGCAGGACGACGAGGACGAGGAGAACAGCGCCTTCGAGTCAGTACCCGACTCCGTGCAGAGCCCTGAGCTGGACCCCGAGGCCACCAATGGCACCGGGCCGTGGCAGGACGAGCTGACCGCGCCCGGAGGGACCGTGGCGAGAACTGCAGAAGGGCTGGAGTCCCCCATGGCAGGTCCGAGCCATCGGAGAGAAGGTGAATGTCCTATTCTCCATAATTCCCAGCCAGTAAGCCAGCTTCCTTCCCTGAGGCCTGAACATCACCACTACCCAACAATCGATGAGCCTCTTCCACCAAACTGGGAAGCTCGGATTGACAGCCATGGGCGGGTCTTTTATGTGGACCATGTGAACCGTACGACCACCTGGCAGCGCCCTACAGCTGCAGCCACCCCGGACGGGATGAGGAGATCCGGCTCAGTCCAGCAGATGGAGCAGCTCAACAGGCGGTATCAAAATATTCAGCGAACCATCGCAACAGAGAGGCCTGAGGAAGATTCTGGCAGCCAAAGCTACGAGCAAGTCCCAGCCGGAGGAGGTGGAGGTGGAGGGAGTGACTCAGAGGCTGAATCTTCCCAGTCAAGCTTAGATCTGAGGAGAGAAGGGTCACTTTCTCCAGTGAATTCACAAAAGATCACCTTGCTGCTGCAGTCCCCCGCTGTCAAGTTCCTCACCAACCCCGAATTCTTCACCGTGTTGCATGCCAATTATAGTGCCTACCGAGTCTTCACCAGTAGTACCTGCTTAAAGCACATGATTTTGAAAGTCCGTCGAGATGCACGCAATTTTGAACGCTACCAGCACAACCGGGACTTGGTGAATTTCATCAACATGTTTGCAGACACTCGGCTGGAGCTGCCCCGGGGCTGGGAGATCAAGACCGACCAGCAGGGAAAGTCTTTTTTTGTGGACCACAACAGTCGAGCCACCACTTTCATCGACCCCCGCATCCCTCTCCAGAACGGCCGCCTGCCCAATCACCTGACTCATCGCCAGCACCTCCAGAGGCTCCGAAGTTACAGCGCCGGCGAGGCCTCAGAAGTTTCTAGAAACAGAGGAGCCTCTTTACTGGCCAGGCCAGGACACAGCCTGGTAGCTGCAATTCGAAGCCAGCATCAACATGAGTCATTGCCCCTGGCATATAATGACAAGATTGTGGCATTTCTTCGCCAGCCAAACATTTTTGAAATGTTGCAAGAGCGCCAGCCAAGCTTGGCGAGAAACCATGCACTCAGGGAGAAAATCCATTACATTCGGACCGAGGGTAATCATGGGCTTGAGAAGTTGTCCTGTGATGCAGATCTAGTCATTCTGCTGAGTCTTTTTGAAGAAGAAATCATGTCCTACGTCCCCCTGCAGGCTTCCTTCCACCCTGGGTACAGCTTCTCTCCCCGCTGCTCACCCTGCTCCTCACCTCAGAACTCCCCAGGTTTACAGAGAGCCAGCGCAAGAGCCCCTTCACCATACCGAAGAGACTTTGAGGCCAAGCTCCGAAATTTCTACAGAAAACTAGAGGCCAAAGGATTTGGGCAGGGTCCAGGAAAAATTAAGCTCATAATTCGCCGGGACCACTTGTTGGAAGGAACCTTCAACCAAGTGATGGCCTATTCCCGGAAGGAGCTCCAGAGGAACAAGCTCTATGTCACCTTTGTTGGAGAGGAGGGCTTGGACTACAGCGGTCCTTCTCGAGAGTTCTTCTTCCTTTTGTCTCAGGAGCTCTTCAACCCTTACTATGGACTCTTTGAGTACTCTGCGAATGATACTTACACGGTGCAGATCAGCCCCATGTCAGCATTTGTAGAAAATCATCTTGAATGGTTTAGGTTTAGTGGTCGAATCCTGGGCCTGGCCCTAATCCATCAGTACCTTCTGGACGCTTTCTTCACGAGGCCCTTCTATAAGGCGCTCCTGAGGCTGCCCTGTGATTTAAGTGACCTGGAATATCTGGACGAGGAATTCCACCAGAGCTTGCAATGGATGAAGGACAACAACATCACAGATATCCTTGACCTCACTTTCACTGTTAATGAAGAGGTTTTTGGACAGGTAACGGAAAGGGAGTTGAAGTCTGGCGGAGCCAACACCCAGGTGACAGAGAAGAACAAGAAGGAGTACATCGAGAGGATGGTGAAGTGGCGGGTGGAGCGTGGCGTGGTGCAGCAGACTGAGGCACTGGTGCGGGGCTTCTACGAGGTCGTAGACTCAAGGCTGGTCTCCGTGTTCGATGCCAGGGAGCTGGAGCTGGTGATTGCTGGTACTGCAGAGATTGACCTGAACGACTGGCGGAATAATACCGAGTACCGGGGAGGCTATCATGACGGGCACCTTGTGATCCGCTGGTTCTGGGCTGCAGTGGAACGCTTCAATAATGAGCAGAGACTGAGATTGCTGCAGTTTGTCACAGGAACCTCAAGCGTGCCCTATGAAGGCTTCGCAGCCCTTCGAGGAAGCAATGGCCTTCGGCGTTTCTGCATTGAGAAATGGGGGAAAATCACATCTCTCCCCAGGGCACACACATGCTTCAACCGATTGGATCTCCCACCATATCCCTCCTACTCCATGTTGTATGAAAAGCTCTTGACAGCAGTAGAAGAAACCAGCACCTTTGGACTTGAGTGA

Related Sequences

XP_004840301.1 Protein

Hecw1 PREDICTED: E3 ubiquitin-protein ligase HECW1 isoform X3 [Heterocephalus glaber]

Length: 1583 aa      View alignments
>XP_004840301.1
MASPSRNSQNRRRCKEPLRYSYNPDQFHNMDIRGGPHDGVTIPRSTSDTDLVTSDSRSTLMVSSSYYSIGHSQDLVIHWDIKEEVDAGDWIGMYLIDEVLSENFLDYKNRGVNGSHRGQIIWKIDASSYFVEPETKICFKYYHGVSGALRATTPSVTVKNSAAPIFKSIGSDETTQGQGSRRLISFSLSDFQAMGLKKGMFFNPDPYLKISIQPGKHSIFPALPHHGQERRSKIIGNTVNPIWQAEQFSFVSLPTDVLEIEVKDKFAKSRPIIKRFLGKLSMPVQRLLERHAIGDRVVSYTLGRRLPTDHVSGQLQFRFEITSSIHPADDEEISLSTEPESAETQSSLMNSLVGSSRVEPPDDVPNPCEILKADPLSEDNEMDGAGNQSLEPAGPVEDVSCIMEAGDQGKAFEEPEGAGEPQDTQPTLSAEELAEGLGLDEEAPPSLLLEDGDALANEEELGQEEAAPGSGAGREEEEEEAEKQEQVEEEEVEMEEGEASNPEQGERALQLRALAKRRSRPCSLPVSELETVIAAACADPETPRTHYIRIHALLHSLPCAREEGGADEEPTLRDASDKDALSEEADTLAADPPALDEDAAEPQGGLPGVGTPGHPEGLLPGPEGDAHPSTGSESDSSPRPGGEHSCEGCDASCCSPSCYSSSCYSTSCYSSSCYSASCHSPSCYNGGSRFASHTRFSSVDSAKVSESTVFSSQDDEDEENSAFESVPDSVQSPELDPEATNGTGPWQDELTAPGGTVARTAEGLESPMAGPSHRREGECPILHNSQPVSQLPSLRPEHHHYPTIDEPLPPNWEARIDSHGRVFYVDHVNRTTTWQRPTAAATPDGMRRSGSVQQMEQLNRRYQNIQRTIATERPEEDSGSQSYEQVPAGGGGGGGSDSEAESSQSSLDLRREGSLSPVNSQKITLLLQSPAVKFLTNPEFFTVLHANYSAYRVFTSSTCLKHMILKVRRDARNFERYQHNRDLVNFINMFADTRLELPRGWEIKTDQQGKSFFVDHNSRATTFIDPRIPLQNGRLPNHLTHRQHLQRLRSYSAGEASEVSRNRGASLLARPGHSLVAAIRSQHQHESLPLAYNDKIVAFLRQPNIFEMLQERQPSLARNHALREKIHYIRTEGNHGLEKLSCDADLVILLSLFEEEIMSYVPLQASFHPGYSFSPRCSPCSSPQNSPGLQRASARAPSPYRRDFEAKLRNFYRKLEAKGFGQGPGKIKLIIRRDHLLEGTFNQVMAYSRKELQRNKLYVTFVGEEGLDYSGPSREFFFLLSQELFNPYYGLFEYSANDTYTVQISPMSAFVENHLEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRLPCDLSDLEYLDEEFHQSLQWMKDNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALVRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAVEETSTFGLE