Details from NCBI annotation

Gene Symbol Otof
Gene Name otoferlin, transcript variant X2
Entrez Gene ID 101698163

Database interlinks

Part of NW_004624738.1 (Scaffold)

For more information consult the page for NW_004624738.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

OTOF ENSCPOG00000000331 (Guinea pig)

Gene Details

otoferlin

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000000288, Guinea pig)

Protein Percentage 94.04%
CDS Percentage 91.87%
Ka/Ks Ratio 0.06382 (Ka = 0.0287, Ks = 0.4491)

OTOF ENSG00000115155 (Human)

Gene Details

otoferlin

External Links

Gene Match (Ensembl Protein ID: ENSP00000272371, Human)

Protein Percentage 93.84%
CDS Percentage 90.59%
Ka/Ks Ratio 0.04967 (Ka = 0.0291, Ks = 0.5856)

Otof ENSMUSG00000062372 (Mouse)

Gene Details

otoferlin

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000073803, Mouse)

Protein Percentage 93.69%
CDS Percentage 88.08%
Ka/Ks Ratio 0.03683 (Ka = 0.0296, Ks = 0.8024)

OTOF ENSRNOG00000009967 (Rat)

Gene Details

Otoferlin

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000046997, Rat)

Protein Percentage 93.37%
CDS Percentage 87.35%
Ka/Ks Ratio 0.03741 (Ka = 0.0328, Ks = 0.8777)

Genome Location

Sequence Coding sequence

Length: 5994 bp    Location: 8690366..8601287   Strand: -
>XM_004839143.1
ATGGCCCTGCTTGTCCACCTCAAGAGCGTCTCGGAGCTGAGGGGCAAGGGCGACCGGATTGCCAAAGTGACTTTCCGAGGGCAGCCCTTCTACTCCCGGGTCCTGGAGAACTGCGAGGATGTGGCCGACTTTGATGAGACATTCCGGTGGCCAGTGGCCAGCAACATTGACAGAAATGAGATGCTGGAGATTCAGATTTTCAACTATAGCAAAGTCTTCAGCAACAAGTTAATCGGGACCTTCCGCATGGTGCTGCAGAAGGTGGTCGAGGAGAACCACGTGGAGGTGACCGACACGCTGATTGACGACAACAATGCTGTCATCAAGACCAGCCTGAATGTGGAGGTCCGGTATCAGGCTGCAGATGGCACAAGGGGCTCCTGGGATGACGAGGACTTCCTGAGGGATGAGTCTCTTCAGGAGGAAGAGAAGGACACTCAGGAGACAGATGGGCTGCTCCCCAGCTCCCGCCCCAGCTCCCGGCCACCGGGAGAGAAGAGCTTCCGGAGAGCCGGGAGGAGGGTGTTCTCTGCCATGAAGCTCGGCAAGAACCGGCCCCACAAGGAGGAACCCCAGAGACAAGATGAGCCAGCAGTGCTGGAGATGGAGGACCTTGACCACCTGGCCATTCGGCTGGGGGATGGCCTGGACCCCGACTCGGCGTCTCTAGCCTCTGTCACAGCTCTTACCACCAATGTCTCCAACAAGAGATCCAAGCCAGACATTAAGATGGAGCCAAGCGCCGGGCGGCCCATGGATTACCAGGTCAGCATCACGGTGATAGAGGCGCGGCAGCTGGTGGGCTTGAACATGGACCCTGTGGTGTGTGTGGAAGTGGGCGATGACAAGAAGTACACCTCCATGAAGGAGTCCACGAACTGCCCCTACTATAATGAGTACTTCGTCTTCGACTTCCACGTCTCTCCTGACGTCATGTTCGACAAAATCATCAAGATCTCGGTGATTCACTCCAAGAACCTGCTGCGCAGCGGCACCCTGGTGGGGTCCTTCAAAATGGATGTGGGGACCGTGTACTCCCAGCCCGAGCACCAGTTCCATCACAAGTGGGCCATCCTGTCCGACCCCGACGACATCTCCGCCGGGCTGAAAGGCTACGTGAAGTGTGACATCGCCGTGGTGGCCAAGGGAGACAACATCAAGACACCGCACAAGGCCAACGAGACAGATGAAGAGGACATTGAGGGGAACTTGCTGCTCCCTGACGGGGTACCCGCGGAACGCCAGTGGGCCCGCTTCTACGTGAAAATTTATCGCGCGGAGGGGCTGCCCAGGATGAACACAAGCCTCATGGCCAACGTGAAGAAGGCTTTCATCGGCGAAAATAAGGACCTCGTTGACCCCTACGTGCAAGTCTTCTTTGCGGGCCAGAAGGGCAAGACTTCGGTGCAGAAAAACAGCTACGAGCCCCTCTGGAATGAGCAGGTTGTCTTCACAGACCTGTTCCCGCCGCTCTGCAAACGCATGAAGGTGCAGATCCGGGACTGTGACAAGGTCAATGACGTGGCCATCGGCACTCACTTCATCGATCTGCGCAAGATTTCCAATGATGGAGACAAAGGCTTCCTGCCCACGCTGGGCCCGGCCTGGGTGAACATGTACGGCTCCACACGCAACTACACACTGCTGGATGAGCACCAGGACCTGAATGAGGGCCTGGGGGAGGGGGTGTCCTTCCGCGCCCGCCTCATGCTGGGCCTGGCGGTGGAGATCCTGGACACCTCCAACCCTGAGCTCACCAGCTCCACAGAGGTGCAGGTGGAGCAGGCCACCCCTGTCTCAGAGAGCTGCACAGGGAGAGTGGAAGAATTCTTTCTATTTGGAGCCTTTCTGGAAGCCTCAATGATCGACCGGAAGAATGGAGACAAACCAATTACCTTTGAGGTGACCATAGGCAACTATGGGAATGAAGTTGATGGCCTGTCAGGACCCCAGAGGCCTCGGCCCCGGAAAGAGCCCGGGGACGAGGAGGAAGTAGACCTGATCCAGAACTCGAGTGATGACGAGGGTGATGATGGCGGGGATCTGGCCTCGGTGTCCTCCACCCCACCCGTGCGCCCCCAGATCACCGACAGGAACTACTTCCACCTGCCCTACCTGGAGTGCAAGCCCTGCATCTACATCAAGAGCTGGTGGGCGGACCAGCGCCGCCGCCTCTACAATGCCAACATCATGGACCACATCGCAGACAAGCTGGAGGAAGGCCTGAACGACGTACAGGAGATGATCAAAACGGAGAAGTCCTACCCCGAGCGCCGCCTGCGTGGGGTGCTGGAGGAGCTCAGCAGCGGCTGCCACCGCTTCCTCTCCCTCGCGGACAAGGACCAGGGCCACTCGTATCGCACCAAGCTGGATCGAGAACGCCTCAAATCATGCATGAGGGAGCTGGAGAGCATGGGGCAGCAGGCCAAGAGCCTGCGCGCTCAGGTGAAGCGGCACACGGTGCGCGACAAGCTGAGGCAGTGCCAGAACTTCCTGCAGAAGCTGCGCTTCCTGGCAGATGAGCCCCAGCACAGCATCCCCGACGTCTTCATCTGGATGATGAGCAACAACAAGCGCGCAGCCTACGCCCGCGTGCCCTCCAGAGACCTGCTCTTCTCCACCGTGGAGGAGGAGCTGGGCAAGGACTGCGCCAAGGTCAAGACGCTGTTCCTCAAGCTGCCGGGGAAGCGGGGCTTTGGCGCAGCGGGCTGGACGGTGCAGGCCAAGCTGGAGCTCTACCTGTGGCTGGGCCTCAGCAAGCAGCGGAAGGACTTCCTGTGTGGCCTGCCCTGCGGCTTCGAGGAGGTCAAGGCGGCCAGGGGCCTGGGCCTGCACTCCTTCCCACCCCTCAGCCTGGTGTACACTAAAAAGCAGGCGTTCCAGCTCCGAGCCCACATGTACCAGGCCCGAAGCCTCTTTGCCGCAGACAGCAGCGGGCTCTCTGACCCCTTTGCCCGAGTCTTCTTCATCAACCAGAGCCAGTGCACAGAGGTGTTGAACGAGACACTGTGTCCCACTTGGGACCAGATGCTGGTGTTTGACAACCTGGAATTGTATGGTGAAGCTCATGAGTTGCGGGAGGACCCTCCCATCACTGTCATCGAAATCTACGATCAGGACAGCATGGGCAAAGCCGACTTCATGGGCCGGACCTTCGCCAAGCCCCTGGTAAAGATGGCAGATGAGGCATACTGCCCGCCCCGCTTCCCGCCCCAGCTCGAGTACTACCAGATCTACCGCGGCAACGCCACAGCTGGAGACCTGCTGGCTGCCTTTGAGCTCCTGCAGATTGGGCCAGCAGGGAAGGCTGACCTGCCCCCCATCAATGCCCCAGTGGACACGGACCGGGGGCCCATCATGCCTGTGCCTGTGGGCATCCGGCCTGTGCTCAGCAAGTACCGGGTGGAGGTGCTGTTCTGGGGCCTGCGGGACCTGAAGCGGGTGAACCTGGCCCAGGTGGACCGGCCTCGGGTAGACATCGAGTGTGCAGGGAAGGGGGTGCAGTCATCCCTGATCCACAACTACAAGAAGAACCCCAACTTCAACACCCTGGTCAAGTGGTTTGAAGTGGACCTCCCCGAGAACGAGCTGCTGCACCCGCCCCTGAACATCCGTGTGGTGGACTGCCGGGCCTTCGGCCGATACACCCTGGTGGGCTCGCATGCCGTCAGCTCCCTGCGCCGCTTCATCTACCGGCCGCCCGAGCACACAGCCCCCAAGTGGAACACCACGGTCAGGCTTCTTTGGGGCAGCTCTATGCTGTGCAATGGGGGTCTTTTCTCTCACCCCCCAGGGGAGGTCGTGGTGAGCATGGAGCCAGAGGTGCCTGTCAGGAAACTGGAGACCATGGTGAAGCTGGACGCGACTTCTGATGCTGTTGTCACGGTGGATGTGGCCGAGGAGGAGAAGGAGAAAAGGAAGAAGAAAAAGGGCAGCGCAGAAGAGCCCGAGGAGGAGGAGCCGGATGAGAGCATGCTGGACTGGTGGTCCAAGTACTTCGCCTCCATCGACACCATGAAGGAGCAACTTCGCCAACAAGAGACCTTGGGAGCTGACTTGGAAGAGAAGGAAGAGGCGGACAACACAGAAGGCCTGAAGGGGCCGATGAAGGGCAAGGAGAAGGCAAGGGCAACAAAGGAGGAGAAGAAGAAACGAGCCCAGAGCCCAGGCCCTGGCCAGGGGTCCGAGGTCCCTGAGAAGAAGAAACCCAAGATTGATGAGCTAAAGGTGTACCCTAAGGAGCTGGAGTCCGAGTTTGACAACTTTGAGGACTGGCTGCACACGTTCAACCTGCTTCGGGGCAAGACCCAGGATGGCGAGGACTGCTCCACTGAGGAGGAGCGCACTGTGGGCCGGTTCAAGGGCTCTCTCTGCGTCTACAAAGTGCCTCTCCCAGAGGACATATCCCGGGAAGCCGGCTACGATCCCACCTTCGGCATGTTCCAGGGCATCCCGAGCAACGACTCCATCAATGTGCTGGTCCGAGTGTATGTGGTCCGGGCCACAGATCTACACCCTGCTGACATCAACGGCAAAGCTGACCCCTACATCGCCATCCGGCTAGGCAAGACCGACATCCGCGACAAGGAGAACTACATCTCCAAGCAGCTCAACCCGGTCTTTGGGAAGTCCTTCGACATCCAGGCCTCCTTCCCCATGGAGTCCATGCTCACGGTGGCTGTGTACGACTGGGACCTGGTGGGCACGGACGACCTCATCGGGGAAACCAAGATCGACCTGGAGAACCGCTTCTACAGCAAACACCGCGCCACCTGCGGCGTGGCCCAGACCTACTCCACACACGGCTACAATGTCTGGAGGGACCCCGCGAAGCCCAGCCAGATCCTCACGCGCCTCTGCAAAGTGGGCAAGGTGGACGGGCCCCACTTCGGGCCCCCCGGGAGAGTGAAGGTGGCCAACCGCGTCTTCACGGGGCCCTCGGAGATCGAGGACGAGAATGGTCAGAGGAAGCCCACTGACGAGCACGTGGCCCTGTCTGCCCTGAGGCACTGGGAGGACATCCCCCGCGTGGGCTGCCGCCTGGTGCCAGAGCACGTTGAGACCCGGCCGCTGCTCAACCCTGACAAGCCAGGCATCGAGCAGGGCCGCCTGGAGCTGTGGGTGGACATGTTTCCCATGGACATGCCGGCCCCCGGGACACCGCTGGACATCTCCCCCCGGAAGCCCAAGAAGTATGAGCTACGGGTCATCGTGTGGAACACAGACGAGGTGGTCCTGGAGGACGACGACTTCTTCACCGGGGAGAAGTCCAGCGACATTTTCGTGCGGGGGTGGCTGAAGGGCCAGCAGGAGGACAAGCAGGACACGGACGTGCATTACCACTCCCTCACTGGGGAGGGCAACTTCAACTGGCGCTACCTGTTCCCCTTCGACTACCTGGCGGCCGAGGAGAAGATCGTCATCTCCAAGAAAGAGTCCATGTTCTCGTGGGACGAGACGGAGTACAAAATCCCCGCGCGCCTCACCCTGCAGATCTGGGATGCAGACCACTTCTCCGCCGACGACTTCCTGGGGGCCATCGAGCTGGACCTGAACCGGTTCCCCCGGGGCGCGAAGACAGCCAAGCAGTGCAGCATGGAGATGGCCACCGGGGAGGTGGATGTGCCACTGGTCTCCATCTTCAAGCAGAAGCGCGTCAAAGGCTGGTGGCCCCTCCTGGCCCGCAATGAGAACGACGAGTTCGAGCTCACGGGCAAGGTGGAAGCTGAGCTGCACTTGCTGACAGCAGAGGAGGCGGAGAAGAATCCAGTGGGCCTGGCCCGCAGTGAACCTGACCCCCTAGAGAAACCCAACCGGCCCGACACAAGCTTCATCTGGTTCTTGAGCCCTCTCAAGTCTGCTCGCTACTTCCTGTGGCACACCTACCGCTGGCTGCTCCTCAAGCTGCTGCTGCTCCTGCTGCTGTTCCTCCTGCTCGCCCTCTTTCTCTACTCTGTGCCTGGCTACCTGGCCAAGAAGATTGTCAGGGCCTGA

Related Sequences

XP_004839200.1 Protein

Otof PREDICTED: otoferlin isoform X2 [Heterocephalus glaber]

Length: 1997 aa      View alignments
>XP_004839200.1
MALLVHLKSVSELRGKGDRIAKVTFRGQPFYSRVLENCEDVADFDETFRWPVASNIDRNEMLEIQIFNYSKVFSNKLIGTFRMVLQKVVEENHVEVTDTLIDDNNAVIKTSLNVEVRYQAADGTRGSWDDEDFLRDESLQEEEKDTQETDGLLPSSRPSSRPPGEKSFRRAGRRVFSAMKLGKNRPHKEEPQRQDEPAVLEMEDLDHLAIRLGDGLDPDSASLASVTALTTNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISAGLKGYVKCDIAVVAKGDNIKTPHKANETDEEDIEGNLLLPDGVPAERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKNSYEPLWNEQVVFTDLFPPLCKRMKVQIRDCDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPELTSSTEVQVEQATPVSESCTGRVEEFFLFGAFLEASMIDRKNGDKPITFEVTIGNYGNEVDGLSGPQRPRPRKEPGDEEEVDLIQNSSDDEGDDGGDLASVSSTPPVRPQITDRNYFHLPYLECKPCIYIKSWWADQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLEELSSGCHRFLSLADKDQGHSYRTKLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRQCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRAAYARVPSRDLLFSTVEEELGKDCAKVKTLFLKLPGKRGFGAAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAARGLGLHSFPPLSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELREDPPITVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPAGKADLPPINAPVDTDRGPIMPVPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPEHTAPKWNTTVRLLWGSSMLCNGGLFSHPPGEVVVSMEPEVPVRKLETMVKLDATSDAVVTVDVAEEEKEKRKKKKGSAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQETLGADLEEKEEADNTEGLKGPMKGKEKARATKEEKKKRAQSPGPGQGSEVPEKKKPKIDELKVYPKELESEFDNFEDWLHTFNLLRGKTQDGEDCSTEEERTVGRFKGSLCVYKVPLPEDISREAGYDPTFGMFQGIPSNDSINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIQASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGVAQTYSTHGYNVWRDPAKPSQILTRLCKVGKVDGPHFGPPGRVKVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCSMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARSEPDPLEKPNRPDTSFIWFLSPLKSARYFLWHTYRWLLLKLLLLLLLFLLLALFLYSVPGYLAKKIVRA