Details from NCBI annotation

Gene Symbol Gen1
Gene Name GEN1 Holliday junction 5' flap endonuclease, transcript variant X3
Entrez Gene ID 101716898

Database interlinks

Part of NW_004624738.1 (Scaffold)

For more information consult the page for NW_004624738.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

GEN1 ENSCPOG00000003059 (Guinea pig)

Gene Details

GEN1 Holliday junction 5' flap endonuclease

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000002769, Guinea pig)

Protein Percentage 73.75%
CDS Percentage 82.91%
Ka/Ks Ratio 0.46388 (Ka = 0.1596, Ks = 0.3441)

GEN1 ENSG00000178295 (Human)

Gene Details

GEN1 Holliday junction 5' flap endonuclease

External Links

Gene Match (Ensembl Protein ID: ENSP00000370653, Human)

Protein Percentage 74.7%
CDS Percentage 83.24%
Ka/Ks Ratio 0.37332 (Ka = 0.1472, Ks = 0.3943)

Gen1 ENSMUSG00000051235 (Mouse)

Gene Details

Gen homolog 1, endonuclease (Drosophila)

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000132098, Mouse)

Protein Percentage 66.18%
CDS Percentage 77.64%
Ka/Ks Ratio 0.38462 (Ka = 0.2105, Ks = 0.5472)

Gen1 ENSRNOG00000004667 (Rat)

Gene Details

GEN1 Holliday junction 5' flap endonuclease (Gen1), mRNA

External Links

Gene Match (Ensembl Protein ID: ENSRNOP00000006470, Rat)

Protein Percentage 67.19%
CDS Percentage 78.01%
Ka/Ks Ratio 0.3847 (Ka = 0.2068, Ks = 0.5374)

Genome Location

Sequence Coding sequence

Length: 2733 bp    Location: 689847..718549   Strand: +
>XM_004839026.1
ATGGGAGTGAATGGCTTGTGGCAAATTTTGGAGCCTGTGAAGCAACACGTCCACCTCCGGAGTCTTAGTGGGCAAACCATTGCGGTTGACCTGAGTGTCTGGGTGTGTGAGGCACAGTCTGTTAGGAAAATGGTGGGGACTGTGACGAAGCCCCACCTCAGGAACTTATTTTTTCGTGTCTCCCATTTAATGCAAATGGATATAAGACTGGTGTTTGTTATGGAGGGGGAACCAGCAAAGCTGAAAGCTGGTGTCATGAGCAAGAGGAATCAGATGCGGTACGGGCCTTCTGGGAAAACAGGGTCTCAGAGAACAGGAAGGTCACGTTTTAAGTTGGTCTTACGAGAGTGCCTTGAAATGCTGGAGTGCCTAGGCGTGCCCTGGGTGCAAGCAGCAGGGGAAGCTGAGGCCATGTGCGCTCACCTCAATGGCACTGGCCGTGCTGACGGCTGCCTCACGGACGACGGCGATGCTTTCCTCTACGGGGCCCAGACGGTGTACAGGAATTTCACCATGAATGCACAGGACCCACATGTTGACTGTTATACCATGTCATCTATCAAGAATAAACTAGGCTTGGACAGAGATGCTCTGGTTGGATTAGCCATACTTCTTGGATGTGATTACCTTCCAAAGGGAGTTCCTGGAGTTGGAAAAGAGCAAGCACTAACACTTATACAGATTTTGAAAGGGGAAAGTTTGCTTCAGAGGTTTAATCAGTGGAATGAAAAGTCTTGCCATTCTGTTCCGCAGCCAGAAGCAGCTGAACTGGCCCATTGCTCTGTGTGTTCCCATCCAGGTTCACTGAAGGATCATGAACGTAATGGTTGCCAGTTATGTAAAAGTAGTAGATACTGTGAACCACATGATTATGAATACTGCTGTCCTTGCGAATGGCATCAGACAAAACATGATAGGCAACTAATCGGAGTAGAGAACAATATTAAGAAGAAGGCTTGCAGTTGTGAGGGATTCCCATTCCATGAGGTTATTCAAGAATTCCTTTTGAACAAGGATAAATTGGTGAGGGTAATAAGATACCAAAGACCTGATTTATTATTGTTTCAGAGATTTACTCTTGAAAAAATGGAGTGGCCCAATCACTATGCATGTAAGAAACTGTTGGTGCTTTTGACCCGCTATGACATGATGGAAAGAAAACTCGGCAGAAAGAACTCCGACCAACTGCAACCAATTCGAATTGTTAAGCCCCGAATCAGAAATGGAGTTCATTGCTTTGAAATAGAATGGGAAATGCCTGAACATTTTGCTGTAGAAGATGGAGAACATGGAGAACTGATTCTAACAGTTGAAGAAGAATCGTTGTTTGAAGCAGCTTATCCTGAGATTGTTGCCATTTACCAAAACCAAAATTTAGAAGCTAAAGGGAGGAAGCAAAACAATATGAAAATTAAGCCTAAAGAAGACAATTTCCCAGAACCATATGATGTAATGAATTTTCAGTCACTTGTGACTTTAAAACCCACACCTGAAATCTTTCCTAAGCTGAATTCCAAGTTAAACTTGGAAATTTCTTCTGATCCCGTATTACCACAGGAAAATATTTCTGCCTCGTTGACTAGCTTGCTTTTACCTGAAGATGCTCCCTGTTTAAATATGCAAGAAGAGTTAATGTCTTCAAGACCTTTGCTTAGTCGGCAAATTAAAGGTGCAAGTAACTCTCTCAATTTGGAATCTGGTCAACCCAATCCTTTATTTCATGATATATCTATGATTACTGATTTACACTTGAGCTCCATTGACTGGGAAGGGACTTCTTTTAGTAATGACTCAGCTGTTCAAGGGAAAGCTGTCTCTTATGATTTACAGTCTGAACTTGAATCAAAGCTATTAGTCACCCCTGGTGATTTTGAAAATATCCCAGAACAGTTGTCATGTGAATCAGGACGGTGGACCACAAACATTAATAAATTGTCACATGGGCATCTTCAGAAGGTTAGTCCTGAAGAACATCTACTTTCTGGCATTAGTGATTTATGTCTTCAGGATTTGCCTTTAAAAGAACGTATATATATGAAATCATCATATCCAGAGAATAATGTACAATCAGATGTTGACCTGAAAACTTTGTCCCTACAAAAGATAAAAGAATCTTATATTGCTAATAGTAGATCTGATTGTCCGTCACATCTTTCAAAGGATCTTCCTGGAATTAATTTGCAAAATGAATCCAGAAACGCTAAAGTTATAAAAGGAGACCAGCTGCATCAAGAAAACTCTAAAGTGAATACTTCTGTACTTTATTCTGTCAATAGTAGTAAAATAGTAAAGACCTCCAATGTTAGAGCTGGGCCACCAAATACTTTTTTAGGTCATAGTGGAAAAGTTAATATGCACACCATTCAGAAACTTGTCAAGAAGAATAGTACTTGCCTTGACAGACATTCCTCTGATGAAGAAAGTGGTCCAGTATTTGGTAAAGTGAAGAACACGACTCGAAAAATGAAACATAGTTCACAGAAGAATGACTTAGCCCAATTTAAAGAAAGTGACCACAACAAACAGAGGAACCCTCCAATCCATGCCAAAGAAACTAAATCGAGTGTTAAGTCTTACAAAACAACTGGAAATGAAGAAAAACATTTCTCAGACCCAGCAAAAACTTCTCTGGGTTTTCTACAGTGTCATAAGAAAGACGATGGCCTTGGTACTTGTTTGGATAGTCCCCTTCCTTTATCCCAGAGATTAAAACTAAGGTTCCAGAACACTTGA

Related Sequences

XP_004839083.1 Protein

Gen1 PREDICTED: flap endonuclease GEN homolog 1 isoform X3 [Heterocephalus glaber]

Length: 910 aa      View alignments
>XP_004839083.1
MGVNGLWQILEPVKQHVHLRSLSGQTIAVDLSVWVCEAQSVRKMVGTVTKPHLRNLFFRVSHLMQMDIRLVFVMEGEPAKLKAGVMSKRNQMRYGPSGKTGSQRTGRSRFKLVLRECLEMLECLGVPWVQAAGEAEAMCAHLNGTGRADGCLTDDGDAFLYGAQTVYRNFTMNAQDPHVDCYTMSSIKNKLGLDRDALVGLAILLGCDYLPKGVPGVGKEQALTLIQILKGESLLQRFNQWNEKSCHSVPQPEAAELAHCSVCSHPGSLKDHERNGCQLCKSSRYCEPHDYEYCCPCEWHQTKHDRQLIGVENNIKKKACSCEGFPFHEVIQEFLLNKDKLVRVIRYQRPDLLLFQRFTLEKMEWPNHYACKKLLVLLTRYDMMERKLGRKNSDQLQPIRIVKPRIRNGVHCFEIEWEMPEHFAVEDGEHGELILTVEEESLFEAAYPEIVAIYQNQNLEAKGRKQNNMKIKPKEDNFPEPYDVMNFQSLVTLKPTPEIFPKLNSKLNLEISSDPVLPQENISASLTSLLLPEDAPCLNMQEELMSSRPLLSRQIKGASNSLNLESGQPNPLFHDISMITDLHLSSIDWEGTSFSNDSAVQGKAVSYDLQSELESKLLVTPGDFENIPEQLSCESGRWTTNINKLSHGHLQKVSPEEHLLSGISDLCLQDLPLKERIYMKSSYPENNVQSDVDLKTLSLQKIKESYIANSRSDCPSHLSKDLPGINLQNESRNAKVIKGDQLHQENSKVNTSVLYSVNSSKIVKTSNVRAGPPNTFLGHSGKVNMHTIQKLVKKNSTCLDRHSSDEESGPVFGKVKNTTRKMKHSSQKNDLAQFKESDHNKQRNPPIHAKETKSSVKSYKTTGNEEKHFSDPAKTSLGFLQCHKKDDGLGTCLDSPLPLSQRLKLRFQNT