Sequence details NCBI ID: XM_004837414.1 (Coding sequence)   Best Hit

Details from NCBI annotation

Gene Symbol Mthfd1
Gene Name methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase, transcript variant X2
Entrez Gene ID 101707403

Database interlinks

Part of NW_004624734.1 (Scaffold)

For more information consult the page for NW_004624734.1 (Scaffold)

Potential Gene Matches

The following genes have been identified as possible homologs of the naked mole-rat gene and compared to it.

MTHFD1 ENSCPOG00000013111 (Guinea pig)

Gene Details

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase

External Links

Gene Match (Ensembl Protein ID: ENSCPOP00000011802, Guinea pig)

Protein Percentage 94.96%
CDS Percentage 92.25%
Ka/Ks Ratio 0.12341 (Ka = 0.0292, Ks = 0.237)

MTHFD1 ENSG00000100714 (Human)

Gene Details

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase

External Links

Gene Match (Ensembl Protein ID: ENSP00000216605, Human)

Protein Percentage 93.05%
CDS Percentage 89.7%
Ka/Ks Ratio 0.10065 (Ka = 0.0356, Ks = 0.3536)

Mthfd1 ENSMUSG00000021048 (Mouse)

Gene Details

methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase

External Links

Gene Match (Ensembl Protein ID: ENSMUSP00000021443, Mouse)

Protein Percentage 92.09%
CDS Percentage 86.2%
Ka/Ks Ratio 0.07008 (Ka = 0.041, Ks = 0.5849)

Genome Location

Sequence Coding sequence

Length: 2808 bp    Location: 36620065..36560486   Strand: -
Raw sequence   
>XM_004837414.1
ATGGCGCCGGCGGGAATCCTGGACGGGAAGGTGGTCTCCGCGCAAATAAGAGAGAGACTGAAGAATCAAGTGGCTCAGATGAAAGAGCAAGTACCTGGCTTCGCACCTGGCCTGGTGATTTTACAGGTTGGCGACAGAGATGATTCCAATCTTTATATAAATGTGAAGCGGAAGGCTGCTGAAGAGATTGGGATCAGAGCCACTCACATTAAATTACCAAGATCAGCCACAGAATCTGAGGTGTTAAAGTATGTCATATCTTTGAATGAAGACTCCACTGTACATGGATTCATAGTACAGCTGCCTTTAGATTCGGAAACTTCTATTAACACTGAGGCAGTCATCAATGCTATTGCTCCCGAAAAGGATGTGGATGGATTGACTAGCATCAATGCTGGAAAACTTGCTCGCGGTGATCTGAATGACTGTTTCATTCCTTGTACGCCCAAAGGATGCTTGGAACTCATCAAAGAGACAGGGGTACAGATTGCTGGAAGTCACGCTGTGGTGGTCGGACGTAGTAAAATAGTGGGTGCCCCAATGCATGACTTGCTGCTGTGGAATAACGCCACTGTGACCACCTGCCATTCCAAGTCTGCCCATCTGGACAAGGAGGTGAACAAAGGTGATATCTTGGTGGTCGCCACCGGTCAGCCTGAAATGGTCAAAGGAGAGTGGATCAAACTTGGGGCAGTTGTCATCGACTGTGGAATCAATTATGTCCCAGACAGTACAAAACCAAATGGAAAGAAAGTGGTAGGCGATGTGGCATACAAGGAGGCCAAGGAGAGGGCAGGCTTCATCACACCTGTCCCTGGTGGTGTCGGGCCCATGACTGTGGCAATGCTGATGCAGAGCACAGTTGAGAGTGCAAAGCGTTTCTTGAAGAAATGTAAACCAGGAAAGTGGATGATGCAGTATAACAATCTCAACCTGAAGACACCTGTTCCAAGTGACATTGAAATCTCACGGTCTTGCAAACCGAAGCCCATTGGTAACCTGGCTCGAGAAATTGGCCTGCTCTCTGGAGAGGTAGAATTATACGGGGAAACAAAGGCCAAGGTCCAGCTGTCAGTGGTGGAGCGCCTGAAGCACCAGCCTGATGGGAAATACGTAGTAGTGACTGGAATAACTCCGACACCCCTGGGAGAAGGAAAAAGTACAACCACAATTGGGCTGGTGCAAGCCCTTGGAGCCCATCTTTACCAGAATGTCTTCGCATGTGTGCGACAGCCTTCTCAGGGCCCCACCTTTGGAATAAAAGGTGGCGCTGCAGGAGGTGGCTACTCCCAAGTCGTTCCTATGGAAGAGTTTAATCTTCACCTCACTGGTGACATCCACGCCATCACTGCAGCTAATAACCTTGTTGCTGCGGCCATTGATGCTCGAATGTTCCATGAACTAACTCAGACTGATAAGGCTCTCTTTAATCGTTTGGTACCATCAATAAATGGAGTAAGAAAGTTCTCTGACATCCAAATCCGAAGGTTACAGAGACTAGGCATTGAAAAGACTGACCCTACCACACTAACAGATGAAGAGATCAACAGATTTTCAAGACTGGATTTTGATCCAGAAACCATAACATGGCAAAGAGTGTTGGACACCAATGATAGATTCCTGAGGAAGATCACAATTGGGCAGTCTCCAACAGAGAAAGGTCACACACGGACGGCTCAGTTCGATATCTCCGTGGCCAGTGAAATCATGGCTGTCTTGGCTCTCACCACTTCTCTCGAAGACATGAGAGAGAGACTAGGCAAAATGGTGGTGGCCTCCAGCAAGAAAGGGGAGCCCATAAGTGCTGAAGACCTGGGGGTGAGCGGCGCGCTGACCGTGCTGATGAAGGATGCGATCAAGCCCAACCTCATGCAGACGTTGGAGGGCACTCCAGTGTTTGTTCATGCTGGACCGTTTGCCAACATTGCGCATGGGAATTCCTCCATCATTGCGGACCGGATAGCGCTCAAGCTTGTGGGCCCTGAGGGCTTTGTCGTGACTGAAGCAGGATTCGGAGCAGACATTGGAATGGAAAAGTTTTTTAACATCAAATGCCGGTATTCTGGCCTCCGCCCTCACGTGGTGGTGCTTGTTGCCACTGTCCGGGCTCTTAAAATGCACGGAGGCGGCCCCACGGTTACTGCTGGATTGCCTCTTCCCAAAGCTTACATAGAAGAGAACCTGGAGCTGGTTGAAAAGGGCTTCAGTAATTTGAGGAAACAAATTGAAAATGCCCAAATGTTTGGAGTCCCAGTGGTAGTGGCTGTGAATGCATTCAAGACAGATACAGAGGCCGAACTGGACCTCATCAGCCGCCTTGCGAGAGACCACGGGGCTTTTGATGCTGTGAAATGCACTCACTGGGCAGAAGGGGGCAAGGGTGCTCTGGCCCTGGCTCAGGCCGTCCAGAGAGCTGCACAAGCACCCAGCAGCTTCCGGCTCCTTTATGACCTCGAGCTCCCTGTTGAGGCTAAGATCAGGATCATCGCGCAGAAGATCTATGGTGCAGACGACATTGAGTTGCTCCCTGCAGCTCAGCACAAAGCTGAAGTCTACACAAAGCAGGGATTTGGGAATCTCCCCATCTGCATGGCTAAAACACACTTGTCCTTGTCTCACGACCCAGAGCAAAAAGGTGTACCTACAGGCTTCGTCCTGCCCATTCGTGACATCCGTGCCAGCGTCGGTGCTGGTTTTCTGTACCCTTTAGTAGGAACGATGAGCACAATGCCTGGACTCCCTACCCGGCCCTGCTTTTATGATATCGATTTAGACCCTGAAACCGAACAGGTGAATGGACTGTTTTAA

Related Sequences

XP_004837471.1 Protein

Mthfd1 PREDICTED: c-1-tetrahydrofolate synthase, cytoplasmic isoform X2 [Heterocephalus glaber]

Length: 935 aa      
>XP_004837471.1
MAPAGILDGKVVSAQIRERLKNQVAQMKEQVPGFAPGLVILQVGDRDDSNLYINVKRKAAEEIGIRATHIKLPRSATESEVLKYVISLNEDSTVHGFIVQLPLDSETSINTEAVINAIAPEKDVDGLTSINAGKLARGDLNDCFIPCTPKGCLELIKETGVQIAGSHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKSAHLDKEVNKGDILVVATGQPEMVKGEWIKLGAVVIDCGINYVPDSTKPNGKKVVGDVAYKEAKERAGFITPVPGGVGPMTVAMLMQSTVESAKRFLKKCKPGKWMMQYNNLNLKTPVPSDIEISRSCKPKPIGNLAREIGLLSGEVELYGETKAKVQLSVVERLKHQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVVPMEEFNLHLTGDIHAITAANNLVAAAIDARMFHELTQTDKALFNRLVPSINGVRKFSDIQIRRLQRLGIEKTDPTTLTDEEINRFSRLDFDPETITWQRVLDTNDRFLRKITIGQSPTEKGHTRTAQFDISVASEIMAVLALTTSLEDMRERLGKMVVASSKKGEPISAEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEAGFGADIGMEKFFNIKCRYSGLRPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYIEENLELVEKGFSNLRKQIENAQMFGVPVVVAVNAFKTDTEAELDLISRLARDHGAFDAVKCTHWAEGGKGALALAQAVQRAAQAPSSFRLLYDLELPVEAKIRIIAQKIYGADDIELLPAAQHKAEVYTKQGFGNLPICMAKTHLSLSHDPEQKGVPTGFVLPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF