CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000003459/1-1024 MLAVGRMEDEEGPEYGKPDFVLLDQLTMEDFMKNLELRFEKGRIYTYIGEVLVSVNPYQE ENSRNOP00000010021/1-1015 ------MEDEEGPEYGKPDFVLLDQLTMEEFMKNLQLRFEKGRIYTYIGEVLVSVNPYQE ENSP00000258787/1-1018 ------MEDEEGPEYGKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQE ENSCPOP00000021188/1-1024 CFLAGRMEDHEGPECGKPDFVLLDQVTMEDFMRNLQLRFEKGLIYTYIGEVLVSVNPYKQ XP_004839951.1/1-1018 ------MEDHEGPECGKPDFVLLDQVTMEDFMRNLQLRFEKGLIYTYIGEVLVSVNPYKQ ***.**** **********:***:**:**:****** ***************:: ENSMUSP00000003459/1-1024 LPLYGPEAIAKYQGRELYERPPHLYAVANAAYKAMKRRSRDTCIVISGESGAGKTEASKH ENSRNOP00000010021/1-1015 LPLYGPEAIAKYQGRELYERPPHLYAVANAAYKAMKRRSRDTCIVISGESGAGKTEASKH ENSP00000258787/1-1018 LPLYGPEAIARYQGRELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKH ENSCPOP00000021188/1-1024 LPLYGPEAIARYQGRELYERPPHLYAVANAAYRAMKRRSRDTCIVISGESGAGKTEASKH XP_004839951.1/1-1018 LPLYGPEAVARYQGRELYERPPHLYALANAAYRAMKRSSRDTCIVISGESGAGKTEASKH ********:*:***************:*****:***: ********************** ENSMUSP00000003459/1-1024 IMQYIAAVTNPSQRAEVERVKNVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKG ENSRNOP00000010021/1-1015 IMQYIAAVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKG ENSP00000258787/1-1018 IMQYIAAVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKG ENSCPOP00000021188/1-1024 IMQYIAAVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKG XP_004839951.1/1-1018 IMQYIAAVTNPSQRAEVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKG *********************:************************************** ENSMUSP00000003459/1-1024 DPVGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDQELQGLHLERNPAVYNFTRQG ENSRNOP00000010021/1-1015 DPVGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDQELQELHLERNPAVYNFTRQG ENSP00000258787/1-1018 DPIGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQG ENSCPOP00000021188/1-1024 DPVGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGSEDQELQRLHLERNPALYNFTRQG XP_004839951.1/1-1018 DPVGGHIHSYLLEKSRVLKQHVGERNFHAFYQLLRGCEDQELQGLHLERNPALYNFTRQG **:*********************************.**::*: ********:****:** ENSMUSP00000003459/1-1024 AGLNMGVHNALDSDEKSHQGVMEAMRIIGFSPDEVESIHRILAAILHLGNIEFVETEENG ENSRNOP00000010021/1-1015 AGLNMG---ALGSDEKSHQGVMEAMKIIGFSPEEVESIHRILAAILHLGNIEFVETEENG ENSP00000258787/1-1018 AGLNMTVHSALDSDEQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGG ENSCPOP00000021188/1-1024 AGLSSGAHGALESDESSHQAVTEAMRVIGFRREEVETVHRVLAAILHLGNIEFVETEDNG XP_004839951.1/1-1018 AGLSSGAQNALESDENSHRAVTEAMRVIGFQPEEVATVHRILAAILHLGNIEFVETEDHG ***. ** ***.**:.* ***::*** :** ::**:****************: * ENSMUSP00000003459/1-1024 PQKGGLEVADEALVGYVAKLTATPRDLVLRTLLARTVASGGREVIEKSHTVAEASYARDA ENSRNOP00000010021/1-1015 PQKGGLEVADEALVGYVAKLTATPSDLVLRTLLARTVASGGREVIEKSHTVAEASYARDA ENSP00000258787/1-1018 LQKEGLAVAEEALVDHVAELTATPRDLVLRSLLARTVASGGRELIEKGHTAAEASYARDA ENSCPOP00000021188/1-1024 LQKGGLAVAEEALVDHVAELTTTPRDLVLRSLLARTVASGGRDLIEKGHTVAEASYARDA XP_004839951.1/1-1018 LRKGGLGVAEEALVDHVAELTATPRDLVLRSLLARTVASGGHDLIEKGHTVAEASYARDA :* ** **:****.:**:**:** *****:**********:::***.**.********* ENSMUSP00000003459/1-1024 CAKAMYQRLFEWVVNKINSIMEPRNRDPRCDGKDTVIGVLDIYGFEVFPVNSFEQFCINY ENSRNOP00000010021/1-1015 CAKAMYQRLFEWVVNKINSIMEPRDRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINY ENSP00000258787/1-1018 CAKAVYQRLFEWVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINY ENSCPOP00000021188/1-1024 CAKAVYQRLFEWVVDRINGIMEARDRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINY XP_004839951.1/1-1018 CAKAVYQRLFEWVVDRINGIMEARGRDPRQDGKDTVIGVLDIYGFEVFPVNSFEQFCINY ****:*********::**.:**.*.**** ****************************** ENSMUSP00000003459/1-1024 CNEKLQQLFIQLILKQEQEEYEREGIAWQTIEYFNNATIVELVEQPHRGILAVLDEACST ENSRNOP00000010021/1-1015 CNEKLQQLFIQLILKQEQEEYEREGITWQSIEYFNNATIVELVEQPRRGILAVLDEACST ENSP00000258787/1-1018 CNEKLQQLFIQLILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHRGILAVLDEACSS ENSCPOP00000021188/1-1024 CNEKLQQLFIQLILKQEQEEYEREGIAWQSVEYFNNATIVELVERPHRGILAVLDEACST XP_004839951.1/1-1018 CNEKLQQLFIQLILKQEQEEYEREGITWQSVEYFNNATIVELVERPHRGILAVLDEACSA **************************:**::*********:***:*:************: ENSMUSP00000003459/1-1024 AGPITDRIFLQTLDTHHRHHPHYSSRQLCPTDKTMEFGRDFQIKHYAGDVTYSVEGFIDK ENSRNOP00000010021/1-1015 AGPITDRIFLQTLDTHHRHHPHYSSRQLCPTDKTMEFGRDFQIKHYAGDVTYSVEGFIDK ENSP00000258787/1-1018 AGTITDRIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDK ENSCPOP00000021188/1-1024 AGTITDRIFLQTLDTHHRHHPHYSSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVDGFIDK XP_004839951.1/1-1018 AGTITDRIFLQTLDTHHRHHPHYSSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDK **.*********** ***** **:*****************:************:***** ENSMUSP00000003459/1-1024 NRDSLFQDFKRLLYNSVDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASK ENSRNOP00000010021/1-1015 NRDSLFQDFKRLLYNSMDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMIALVENLASK ENSP00000258787/1-1018 NRDFLFQDFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASK ENSCPOP00000021188/1-1024 NRDFLFQDFKRLLYNSSDPTLRAMWPDGQQDITEVTKRPLTAGTIFKNSMVALVENLASK XP_004839951.1/1-1018 NRDFLFQDFKRLLYNSSDPTLRAMWPDGQQDITEVTKRPLTAGTIFKNSMVALVENLASK *** ************ ***************************:*****:********* ENSMUSP00000003459/1-1024 EPFYVRCIKPNEDKVAGRLDEAHCRHQVEYLGLLENVRVRRAGFASRQPYPRFLLRYKMT ENSRNOP00000010021/1-1015 EPFYVRCIKPNEDKVPGRLDEAHCRHQVEYLGLLENVRVRRAGFASRQPYPRFLLRYKMT ENSP00000258787/1-1018 EPFYVRCIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMT ENSCPOP00000021188/1-1024 EPFYVRCIKPNEDKVPGRLDENHCRHQVSYLGLLENVRVRRAGFASRQPYPRFLLRYKMT XP_004839951.1/1-1018 EPFYVRCIKPNEDKVPGMLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMT ***************.* *** ****** *********************.********* ENSMUSP00000003459/1-1024 CEYTWPNHLLGSDRDAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIV ENSRNOP00000010021/1-1015 CEYTWPNHLLGSDREAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVTLEQSRAHLIPIIV ENSP00000258787/1-1018 CEYTWPNHLLGSDKAAVSALLEQHGLQGDVAFGHSKLFIRSPRTLVTLEQSRARLIPIIV ENSCPOP00000021188/1-1024 CEYTWPNHLLGSDKAAVSALLEQHGLQGDVAFGHNKLFIRSPRTLVTLEQSRAQLIPIIV XP_004839951.1/1-1018 CEYTWPNHLLGSDRAAVGALLEQHGLQGDVAFGHSKLFIHSPRTLVTLEQSRARLIPIIV *************: **.****************.****:*************:****** ENSMUSP00000003459/1-1024 LLLQKAWRGTLARWHCRRLRAIYTIMRWFRRHKVRAHLIELQRRFQAARQPPLYGRDLVW ENSRNOP00000010021/1-1015 LLLQKAWRGTLARWRCRRLRAIYTIMGWFRRHKVRAHLIELQRRFQAARQPPLYGRDLVW ENSP00000258787/1-1018 LLLQKAWRGTLARWRCRRLRAIYTIMRWFRRHKVRAHLAELQRRFQAARQPPLYGRDLVW ENSCPOP00000021188/1-1024 LLLQKAWRGTLARWRCRRLRAVYTIMRWFRRHKVRAHLAELQRRFQAARQPPLYGRDLEW XP_004839951.1/1-1018 LLLQKAWRGTLARWHCRRLRAVYTIMRWFRRHKVRAHLAELQLRFQDARQPPLYGRDLEW **************:******:**** *********** *** *** *********** * ENSMUSP00000003459/1-1024 PTPPAVLQPFQDTCRVLFSRWRARQLVKNIPPSDMIQIKAKVAAMGALQGLRQDWGCQRA ENSRNOP00000010021/1-1015 PTPPAVLQPFQDTCHILFSRWRARQLVKNIPPSDMTQIKAKVAAMGALQGLRQDWGCQRA ENSP00000258787/1-1018 PLPPAVLQPFQDTCHALFCRWRARQLVKNIPPSDMPQIKAKVAAMGALQGLRQDWGCRRA ENSCPOP00000021188/1-1024 PSPPAVLQPFQDTCQALFCRWRARQLVKNIPPSDMAQIKAKVAAMGALQGLRQDWGCRRA XP_004839951.1/1-1018 PPPPAVLQPFQDTCRALFCRWRARQLVKNIPPSDMAQIKAKVAAMGALQGLRQDWGCQRA * ************: **.**************** *********************:** ENSMUSP00000003459/1-1024 WARDYLSSDTDNPTASHLFAEQLKALREKDGFGSVLFSSHVRKVNRFRKSRDRALLLTDR ENSRNOP00000010021/1-1015 WARDYLSSDTDNPTASHLFAEQLKALREKDGFGTVLFSSHVRKVNRFRKRRDRALLLTDR ENSP00000258787/1-1018 WARDYLSSATDNPTASSLFAQRLKTLQDKDGFGAVLFSSHVRKVNRFHKIRNRALLLTDQ ENSCPOP00000021188/1-1024 WARDYLSSGSDNPAASGLFADRLKTLRDKDGFGAVLFSSHVRKVNRFRKRRDRALLLTDR XP_004839951.1/1-1018 WTRDYLSSGTENPAASGLFAERLKTLRDKDGFGAVLFSSHVRKVNRFRKSRDRALLLTDR *:****** ::**:** ***::**:*::*****:*************:* *:*******: ENSMUSP00000003459/1-1024 YLYKLEPGRQYRVMRAVPLEAVTGLSVTSGRDQLVVLHAQGYDDLVVCLHRSQPPLDNRI ENSRNOP00000010021/1-1015 HLYKLEPGRQYRVMRAVPLDAVTGLSVTSGRDQLVVLHAQGHDDLVVCLHRSQPPLDNRI ENSP00000258787/1-1018 HLYKLDPDRQYRVMRAVPLEAVTGLSVTSGGDQLVVLHARGQDDLVVCLHRSRPPLDNRV ENSCPOP00000021188/1-1024 HLYKLDPGRQYRVMRSVPLDTVTGLSVTSGQDQLVVLHARNQDDLVVCLHRSHPPLDNRI XP_004839951.1/1-1018 HLYKLDPGRQYRVMRSVALDVVTGLSVTSGRDQLLVLHTRGQDDLVVCLHRSQPPLDNRI :****:*.*******:*.*:.********* ***:***::. **********:******: ENSMUSP00000003459/1-1024 GELVGMLAAHCQGEGRTLEVRVSDCIPLSQRGARRLISVEPRPEQPEPDFQSSRSTFTLL ENSRNOP00000010021/1-1015 GELVGMLVSHCQGEGRTLEIRVSDCIPLSQRGARRLISVEPRPEQTEPDFQCSRSTFTLL ENSP00000258787/1-1018 GELVGVLAAHCQGEGRTLEVRVSDCIPLSHRGVRRLISVEPRPEQPEPDFRCARGSFTLL ENSCPOP00000021188/1-1024 GELVGVLAAHCQGEGQALEVRVSDCIPLSQRGARRLVSVEHRPEQPEPDFRCSRGAFTLL XP_004839951.1/1-1018 GELVGVLAAHCQGEGQALEVRVSDCIPLSQRGARRLVSVEPRPEQLEPDFHCSRGAFTLL *****:*.:******::**:*********:**.***:*** **** ****:.:*.:**** ENSMUSP00000003459/1-1024 WPSH ENSRNOP00000010021/1-1015 WPSH ENSP00000258787/1-1018 WPSR ENSCPOP00000021188/1-1024 WPSR XP_004839951.1/1-1018 WPSR ***: