CLUSTAL W(1.81) multiple sequence alignment XP_004847408.1/1-710 MAEVGRRSVCDSYALLPGGFWAAVAVWLERPQVANKRLCGARLEARQSATLPRAEALRPR ENSCPOP00000019786/1-711 MAEVGRARVCDPGELLPEGFWAAVAVWLERPQVANKRLCGARLEARRRATLPRAEA---- ENSP00000374387/1-757 MAEVGRTGISYPGALLPQGFWAAVEVWLERPQVANKRLCGARLEARWSAALPCAEARGPG ENSMUSP00000030980/1-713 MEELGRVRLSDPDALLPAGFWAAVTVWLERPQVANKRLCGARMEARGRTLRSHAQA---- ENSRNOP00000011824/1-705 MEELRRVPLDDPDSLLPGGFWAAVTVWLERPQVANKRLCGARIEARGRTLRPSAQA---- * *: * : . *** ****** *****************:*** : . *:* XP_004847408.1/1-710 LSAGPDQEWGAALCRPQEGPGTRWGSPEEDHGTWPSAGPEQERGAALCGPQERPGPGRSS ENSCPOP00000019786/1-711 -----------------------------------------RRG---------PGSGLG- ENSP00000374387/1-757 TSAGSEQ---------------------------------KERG---------PGPGQGS ENSMUSP00000030980/1-713 -----------------------------------------ECG---------PRQGQG- ENSRNOP00000011824/1-705 -----------------------------------------ECG---------PRQGQG- . * * * . XP_004847408.1/1-710 VEGHPGPRPGVGPEEDTSCLRLEETQGPPQQGKEQREAAAAPLLAE----QPHRTGSGEE ENSCPOP00000019786/1-711 -------------------------------RGLIRTPGRPGPRPGIPRGRPRPAGGGEE ENSP00000374387/1-757 PGGGPGPRSLSGPEQGTACCELEEAQGQCQQEEAQREAASVPLRDS---GHPGHAEGREG ENSMUSP00000030980/1-713 -------------------------------HGLEREPGQASPKGE---PESGPRASREG ENSRNOP00000011824/1-705 -------------------------------HGLEREPGQ------------GSRADREG * .. . * XP_004847408.1/1-710 DDPAADLGSLWDRFSQSLVCGHPEMLSFLTRSGAESQTEAPHELDLVLRTVIPKTSPHFL ENSCPOP00000019786/1-711 NDPAAELDSLWDRFSQSLVSGSTEMLSFLTSSGAGSQSEAPHELDLVLRTVIPKKSPHCL ENSP00000374387/1-757 DFPAADLDSLWEDFSQSLARGNSELLAFLTSSGAGSQPEAQRELDVVLRTVIPKTSPHCP ENSMUSP00000030980/1-713 TAPAADLNSLWDRVSQSLVHANPEMLAFLCGPSLGPQPEAAQELDLILRTVIPKASPHSP ENSRNOP00000011824/1-705 TAPAADLDLLWNRVSQSLVHSNPEILTFY-GPSLGSPPEAAQELDLVLRTVIPKASPHFP ***:*. **: .****. . .*:*:* .. . .** :***::******* *** XP_004847408.1/1-710 VTAPRREIVVQDVPNGTVTFLPLEEDDEGNLEVKMSNVYQIQLSRSPAEWFISVLIFCPE ENSCPOP00000019786/1-711 VTAPRREIVVQDVPSGTVTFLPLEEDDEGNLEVKMSLVYQIQLRPSQAEWFISVLIFCPE ENSP00000374387/1-757 LTTPRREIVVQDVLNGTITFLPLEEDDEGNLKVKMSNVYQIQLSHSKEEWFISVLIFCPE ENSMUSP00000030980/1-713 LTEPKKELVVQDVSSGSVTFLPLEEDNEGNLEVKTSNVYQLHLHHNEGEWFISVLIFCPE ENSRNOP00000011824/1-705 FTEPKKELVVQDVSSGSVTFLPLEEDNEENLEVKMSNVYQLRLHHSEGEWFISVLIFCPE .* *::*:***** .*::********:* **:** * ***::* . ************ XP_004847408.1/1-710 KWQSDGAIYPRCTWLGGELLGRLARWCVASSKRELRSTLSLVSIGRYSVLYQELKEKYRD ENSCPOP00000019786/1-711 KWHSDGVVHPRPAWLGGELLGRLARWCVASRKSEFPSTLSLVSIERYSVLYQELKEKYRD ENSP00000374387/1-757 RWHSDGIVYPKPTWLGEELLAKLAKWSVENKKSDFKSTLSLISIMKYSKAYQELKEKYKE ENSMUSP00000030980/1-713 RWHSDGVVYPKPAWLGEELLSKLARWAVENRKSEFKSTLSLVSILRYSRMYQELKEKYRD ENSRNOP00000011824/1-705 RWHSDGVVYPKPTWLAEELLSKLARWAVENRKSEFKSTLSLVSVLRYGRMYQELKEKYRD :*:*** ::*: :**. ***.:**:*.* . * :: *****:*: :*. ********:: XP_004847408.1/1-710 MVRVWPEVTDPEKFVYEDVAIASYLLILWEEERAERGVSTPQSFVDLGCGNGLLVHILCN ENSCPOP00000019786/1-711 MVKVWPEVTDPEKFVYEDVAIATYLLILWEEEREERGVCARQSFVDLGCGNGLLVHILCS ENSP00000374387/1-757 MVKVWPEVTDPEKFVYEDVAIAAYLLILWEEERAERRLTARQSFVDLGCGNGLLVHILSS ENSMUSP00000030980/1-713 MVKVWPEVTDPEKFVYEDVAIATYLLILWEEERAEKGVTTKQSFVDLGCGNGLLVHILSN ENSRNOP00000011824/1-705 MVKVWPEVTDPEKFVYEDVAIATYLLILWEEERAEKGITTKQSFVDLGCGNGLLVHILSN **:*******************:********** *: : : *****************.. XP_004847408.1/1-710 EGHPGRGIDVRRRKIWDMYGPHTQLEENAITPSAQTLFPAADWLIGNHSDELTPWIPVIA ENSCPOP00000019786/1-711 EGHPGRGIDVRRRKIWDMYGPHTQLEEDAIAPSDRTLFPDVDWLIGNHSDELTPWIPVLA ENSP00000374387/1-757 EGHPGRGIDVRRRKIWDMYGPQTQLEEDAITPNDKTLFPDVDWLIGNHSDELTPWIPVIA ENSMUSP00000030980/1-713 EGHPGRGIDIRRRKIWDMYGPQTQLEEGSITPSDETLFPGVDWLIGNHSDELTPWIPVIA ENSRNOP00000011824/1-705 EGHPGRGIDVRRRKIWDMYGPQTQLEEGSITPSDKTLFPGVDWLIGNHSDELTPWIPVIA *********:***********:*****.:*:*. .**** .*****************:* XP_004847408.1/1-710 ARSSYHCRFFVLPCCFFDFAGRFCRRQSRKTQYREYLDFIREVGEACGFHMEEDCLRIPS ENSCPOP00000019786/1-711 ARSSYRCRFFVLPCCFFDFVGRYHRRQSRKTQYREYLDFVREVGQACGFLVQEDCLRIPS ENSP00000374387/1-757 ARSSYNCRFFVLPCCFFDFIGRYSRRQSKKTQYREYLDFIKEVGFTCGFHVDEDCLRIPS ENSMUSP00000030980/1-713 ARSSYTCRFFVLPCCFFDFVGRYQRQQSRKTQYREYLDFVLEVGLSCGFHVQEDCLRIPS ENSRNOP00000011824/1-705 ARSSYTCRFFVLPCCFFDFVGRYRRRQSKKTQYREYLDFVLEVGLSCGFHVQEDCLRIPS ***** ************* **: *:**:**********: *** :*** ::******** XP_004847408.1/1-710 TKRVCLIGKSRTYPPAEEA---------------------GGRFAVEQKEVTRRKSSGGD ENSCPOP00000019786/1-711 TKRVCLIGKARLYPPASEASVDQRRIQYIHSRRGL----SGGE--PPCPALQAAACDAAH ENSP00000374387/1-757 TKRVCLVGKSRTYPSSREASVDEKRTQYIKSRRGCPVSPPGWELSPSPRWVAAG--SAGH ENSMUSP00000030980/1-713 TKRVCLIGKSRTYPPSAEVWMDEQRTRYLHSRQGHPQSRPGGAHAPSAPQTAAH--DAGL ENSRNOP00000011824/1-705 TKRVCLIGKSRTYLPSAEVWMDEQRTRYLHSRQGLPQSLPGGGHAPSVPQIAAHDDDAGH ******:**:* * .: *. * ... XP_004847408.1/1-710 LQG---LERRREPVLGRSGLAAGQGDPA-----------EAEARVRRPA----------- ENSCPOP00000019786/1-711 PDRDRALGTGAQDDLGDLVPEHGPEAQAGGSWVPGFHPREKVERVRNCAALPRDFTERVV ENSP00000374387/1-757 CDGQQALDARVGCVTRAWAAEHGAGPQAEGPWLPGFHPREKAERVRNCAALPRDFIDQVV ENSMUSP00000030980/1-713 QDSCRTVNAGSECVLEGLAAERGAGAPAPGLWVPGFCPREKAERVRNCAALPRDFVDQVV ENSRNOP00000011824/1-705 QDSHRTFDAGAECMPEGLAAERGTGAPATGLWVPGFCPREKAERVRNCAALPRDFIDQVV : . * * * ***. * XP_004847408.1/1-710 -DAAAQQPPGVRSSGRPSPHSRLAAGAAEGEAPRGQAGTEF------------GGLQDP- ENSCPOP00000019786/1-711 LQVASLLLGGEKPKPGSPREGTQKAWNGGGSLALAEVAQQLDSATLHRLKRECGGLQTLL ENSP00000374387/1-757 LQVANLLLGGKQLNTRSSRNGSLKTWNGGESLSLAEVANELDTETLRRLKRECGGLQTLL ENSMUSP00000030980/1-713 LQVANLLLDRKKFNTGNSEARSLKPWNGGGSLSLAEVAAELNSETLQRLKRECGGLQTLL ENSRNOP00000011824/1-705 LQVANLLLDGKRFNTGNSEAGSLKTWNGGGSLSLAEVAAELNSETLQQLKRECGGLQTLL :.* : . . . . . . .:.. :: **** XP_004847408.1/1-710 ---HL------------------LVLHAPP---RRLRAAFHQLPVCPW-----APGAAPA ENSCPOP00000019786/1-711 RNSHQVFEVLDGRVRIRDWRQE-LQRKKHSAAMQGPSSEAFKTRAC-WFFMHHPDGCVLP ENSP00000374387/1-757 RNSHQVFQVVNGRVHIRDWREETLWKTKQPEAKQRLLSEACKTRLC-WFFMHHPDGCALS ENSMUSP00000030980/1-713 KNSHQVFEVLNGRVHIRDWRQE-LQRGKPPEAKQNLSAAVFKTRIC-WFFAHHPDGCVLP ENSRNOP00000011824/1-705 RNSHQVFEVLNGRVHIRDWRRE-LQREKPPEGKRSLSAEVFKTRIC-WFFTHHPDGCVLP * * . : : : * * . *.. . XP_004847408.1/1-710 PAPQEEEAGAVSHRPWNQASRGR--- ENSCPOP00000019786/1-711 SASCPFAHGPQELRPPRPLKK-RQAP ENSP00000374387/1-757 TDCCPFAHGPAELRPPRTTPRKKIS- ENSMUSP00000030980/1-713 AAQCPFAHGPEELRLSQTLKKQRQAP ENSRNOP00000011824/1-705 AACCPFAHGLEELRPSQTLKKQRQAP . * . * . : :