CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000023270/1-856 --------------------------------------------------MAVARVDGAL ENSRNOP00000002191/1-845 --------------------------------------------------MAVARVDGAL ENSP00000325881/1-891 --------------------------------------------------MAVARVDAAL ENSCPOP00000019666/1-832 --------------------------------------------------MAVARADSAL XP_004858050.1/1-911 MGDGVYIIRQPIGPSAAVHPGSYSFRLFPPTPSSTKRRRTVAWCSYQAASMAVARADSAL *****.*.** ENSMUSP00000023270/1-856 APGEGSVVNWSGQGLQKLGANLPCEADVHTLILDKNQIIKLENLEKCKQLIQLSVANNRL ENSRNOP00000002191/1-845 APGEGSVVNWSGQGLQKLGANLPCDADVHTLILDKNQIIKLENLEKCKQLIQLSVANNRL ENSP00000325881/1-891 PPGEGSVVNWSGQGLQKLGPNLPCEADIHTLILDKNQIIKLENLEKCKRLIQLSVANNRL ENSCPOP00000019666/1-832 PPGEGSVVNWSGQGLQKLGPNLPCEADIHTLILDKNQIIKLENLEKCKQLIQLSVANNRL XP_004858050.1/1-911 PLGEGSVVNWSGQGLQKLGPNLPCETDIHTLILDKNQIIKLENLEKCKQLIQLSVANNRL . *****************.****::*:********************:*********** ENSMUSP00000023270/1-856 VRMMGVAKLTQLRVLNLPHNSIGCVEGLKDLVHLEWLNLAGNNLKTMEQVNSCTALQHLD ENSRNOP00000002191/1-845 VRMMGVAKLTQLRVLNLPHNSIGCMEGLKDLVHLEWLNLAGNNLKTMEQINSCSALQHLD ENSP00000325881/1-891 VRMMGVAKLTLLRVLNLPHNSIGCVEGLKELVHLEWLNLAGNNLKAMEQINSCTALQHLD ENSCPOP00000019666/1-832 VRMMGVAKLTQLRVLNLPHNSIGYVEGLKELVHLEWLNLAGNNLKAMEQINSCTALQHLD XP_004858050.1/1-911 VRMMGVARLTQLCVLNLPHNSIGYVEGLKELVHLEWLNLAGNNLKAMEQINSCTALQHLD *******:** * ********** :****:***************:***:***:****** ENSMUSP00000023270/1-856 LSDNNIPQIGDVSKLISLKTLLLHGNIITSLRMAPAYLPRNLSILSLAENEIRDLNEISF ENSRNOP00000002191/1-845 LSDNNIPQIGDVSKLTALKTLLLHGNIITSLRMAPAYLPRNLSILSLAENEIRDLNEISF ENSP00000325881/1-891 LSDNNISQIGDLSKLVSLKTLLLHGNIITSLRMAPAYLPRSLAILSLAENEIRDLNEISF ENSCPOP00000019666/1-832 LSDNSIHQIGDLSKLISLKTLLLHGNIITSLRVVPAYLPRSLAILSLAENEIRDLNEVSF XP_004858050.1/1-911 LSDNNIHQIGDLSKLISLKTLLLHGNIITSLRMAPAYLPRSLAILSLAENEIRDLNEVSF ****.* ****:*** :***************:.******.*:**************:** ENSMUSP00000023270/1-856 LASLSELEQLSIMNNPCVMATPSIPGFDYRPFIVSWCLNLRVLDGYVISQKESLKAEWLY ENSRNOP00000002191/1-845 LASLSELEQLSIMNNPCVMATPSIPGFDYRPYIVSWCLNLRVLDGYVISQKESLKAEWLY ENSP00000325881/1-891 LASLTELEQLSIMNNPCVMATPSIPGFDYRPYIVSWCLNLRVLDGYVISQKESLKAEWLY ENSCPOP00000019666/1-832 LASLTELEQLSIMNNPCVMATPSIPGFDYRPYIVSWCLNLRVLDGYVISQKESLKAEWLY XP_004858050.1/1-911 LASLTELEQLSIMNNPCVMATPSIPGFDYRPYIVSWCLNLRVLDGYVISQKESLKAEWLY ****:**************************:**************************** ENSMUSP00000023270/1-856 SQGKGRSYRPGQHIQLVQYLATVCPLTSALGLQTAEDAKLEKILSKQRFHQRQLMSQSQD ENSRNOP00000002191/1-845 SQGKGRSYRPGQHVQLVQYLATVCPLISALGLQTAEDAKLEKILSKQRFHQRQLMNQSQN ENSP00000325881/1-891 SQGKGRAYRPGQHIQLVQYLATVCPLTSTLGLQTAEDAKLEKILSKQRFHQRQLMNQSQN ENSCPOP00000019666/1-832 SQGKGRAYRPGQHIQLVQYLTTVCPLTSILGLQTAEDAKLEKILSKQRFHQRQLMNQSQN XP_004858050.1/1-911 SQGKGRAYRPGQHIQLVQYLATVCPLTSILGLQTAEDAKLEKILSKQRFHQRQLMSQSQN ******:******:******:***** * **************************.***: ENSMUSP00000023270/1-856 EELSPLAAVETRVHRTPECSSPGQD---FQESEPVLQINSWVGISSNDDQLYAVKNNFPA ENSRNOP00000002191/1-845 EELSPIAAVETRVPRTPECSSPVQD---FQESEPVLQINSWVGSSSNDDQLYAVKNNFLA ENSP00000325881/1-891 EELSPLVPVETRASLIPEHSSPVQDCQISQESEPVIQVNSWVGINSNDDQLFAVKNNFPA ENSCPOP00000019666/1-832 EELSSLIPVETRVPLVPEHSSPVQDCLIVQESEPVVQINSWVGINNNDDQLYTAKNNFPA XP_004858050.1/1-911 EELSSLVPIEKNPPLVPERSSPVQDCLIVQESEPVVQVNSWVGISNNDDKLHAAKNNFPA ****.: .:*.. ** *** ** ******:*:***** ..***:*.:.**** * ENSMUSP00000023270/1-856 AAHAARYSRNDLHLEDIQTDEDKLNCSLLSSESTFMPVASGLSPVSPTVELRLQGINLGL ENSRNOP00000002191/1-845 TTHATRYSRNDLHLEDIQTDEDKLNCSLLSSESTFMPVASGLSPVSPTVELRLQGINLGL ENSP00000325881/1-891 SVHTTRYSRNDLHLEDIQTDEDKLNCSLLSSESTFMPVASGLSPLSPTVELRLQGINLGL ENSCPOP00000019666/1-832 SAHTARYSRNDLHLEDIQTDEDKLNCSLLSSESTFMPVASGLSPVSPTVELRLQGINLGL XP_004858050.1/1-911 SAHTTRHSRNDLHLEDIQTDEDKLNCSLLSSESTFMPVASGLSPVSPTVELRLQGINLGL :.*::*:*************************************:*************** ENSMUSP00000023270/1-856 EDDDGADEFTKGLENQDEDKDKEKSLWDMSESCVEMLKRKISTEVSEAAGLLPCPKSVII ENSRNOP00000002191/1-845 EDDDGTDEFTKGLEHQDLDKDREKSLWDSD---VQMLKRKISTEGNEEAGLLPCPKSSII ENSP00000325881/1-891 EDDGVADESVKGLESQVLDKEEEQPLWAANENSVQMMRSEINTEVNEKAGLLPCPEPTII ENSCPOP00000019666/1-832 EDDGVMDESMKGLENQDLDKEKENALWGTNENSGELLKSKISTEVDEKGKLLPCPEPMII XP_004858050.1/1-911 EDAGVVDESLKGLEIQDFDKEEEKALWDINENSVQLLKSKISTEVNEKSGLLSCPEPTII ** . ** **** * **:.*:.** . :::: :*.** .* . **.**:. ** ENSMUSP00000023270/1-856 SAALKEDTHSLTSLPESAGHSAS------RTEANSEEAMSPATSEKFPCRILTQRPAALG ENSRNOP00000002191/1-845 TALLKEDNHSLT----SGGHSVS------HTEPNREEVMSPTTSEKFPCRIFTQRPVALG ENSP00000325881/1-891 SAILKDDNHSLTFFPESTEQKQSDIKKPENTQPENKETISQATSEKLPM-ILTQRSVALG ENSCPOP00000019666/1-832 SAISKDNNHSLTCFPESAGHHVS------HTEP--------------------------- XP_004858050.1/1-911 SAVSKDDNHSLTCFPESAGHSVS------HTEPDSEETMSQTTSEKLPCRILTQRSVALG :* *::.**** * : * .*:. ENSMUSP00000023270/1-856 QDKVTLQKLNAAATKLQACWRGFYTRNYNQQAKGVRYEIRLRRMQEHIVCLTDEVRRLRK ENSRNOP00000002191/1-845 QDKVTLQKLNAAATKLQACWRGFYTRNYNPQAKGVRYEIRLRRMQEHIVCLTDEVRRLRK ENSP00000325881/1-891 QDKVALQKLNDAATKLQACWRGFYARNYNPQAKDVRYEIRLRRMQEHIVCLTDEIRRLRK ENSCPOP00000019666/1-832 -DKVSLQKLNEAVTKLQACWRGFCTRNYNPQAKEVRYEIRLRRMQEHIVCLTDEVRRLRK XP_004858050.1/1-911 QDKVSLQKLNEAATKLQACWRGFYARSYNPQAKELRYEIRLRRMQEHIVCLTDEVRRLRK ***:***** *.********** :*.** *** :*******************:***** ENSMUSP00000023270/1-856 ERDEERVKTFVQEEAVRFLWNE--------------------------VRSVQAWQQTVE ENSRNOP00000002191/1-845 ERDEERVKNFVQEEAVRVLWNE--------------------------VRALQAWQQTVE ENSP00000325881/1-891 ERDEERIKKFVQEEAFRFLWNQKWGLAILPRPVSNFWAQAVFPPQPPKVRSLQVWQQTVD ENSCPOP00000019666/1-832 ERDEERAKKVVQEEAVKFLWNQ--------------------------VRSLQAWQQTVD XP_004858050.1/1-911 ERDEERVKKVVQEEAVRFLWNQ--------------------------VRSLQAWQQTVD ****** *..*****.:.***: **::*.*****: ENSMUSP00000023270/1-856 QRLASWPPDVPPISSTLASPKPPLFPHHQDPSSDQSSDWLVAEDEAAQGRSAPDFPDSGF ENSRNOP00000002191/1-845 QRLVSWHSDVPPISSTLVSPKPPLLPQHQDPSSDQNSDWLIIEDDAPQEKSVPDFPDSGF ENSP00000325881/1-891 QRLSSWHTDVPPISSTLVPSKHPLFTQSQESSCDQNADWFIASDVAPQEKSLPEFPDSGF ENSCPOP00000019666/1-832 QHLSSWHTEA-PVSSTLVTADPPLFTQSQEPSSDQNSNWFIGYDEALEEKALPEFPDSGF XP_004858050.1/1-911 QRLISWHTDVPPVSSTLVPAEPPLFTQSQEPSPDQNSNWFIAYDEALQDKFLPEFPDSGF *:* ** .:. *:****.... **:.: *:.* **.::*:: * * : : *:****** ENSMUSP00000023270/1-856 HSSLTEQVPCLQDSLDFEKSSVESSENSVLGNSADTVKCVKDRDSEATAEEH-SDCSRES ENSRNOP00000002191/1-845 HSSLTEQVHCLQDSLDFEKSSVESSENSALGNSADTVKYVKDPDSEATAEEH-SDCSKES ENSP00000325881/1-891 HSSLTEQVHSLQHSLDFEKSSTEGSESSIMGNSIDTVRYGKESDLGDVSEEH-GEWNKES ENSCPOP00000019666/1-832 HSSLSEQVHCLKDSLDFEKSSTEGSEGSIMGNSIDTVKYGREPDVGDASEEHSGEESKES XP_004858050.1/1-911 HSTLTEDVHCLKDSLDFEKSSTEGSESSIMGNSIDTVKYGKEPDLGDVSEEHSGDWDKEN **:*:*:* .*:.********.*.**.* :*** ***: :: * .:*** .: .:*. ENSMUSP00000023270/1-856 SASEQDNTLLQQYLTSVQQLDDAAEAADSDDVAGDGKRHLACSPERFDASSD----SETH ENSRNOP00000002191/1-845 STSEQDNTLLQQYLASVQQLDDADDRAGPDDMAGDNKRLLACSPERLGA-SD----SEAH ENSP00000325881/1-891 SNNEQDNSLLEQYLTSVQQLEDADERTNFDTETRDSKLHIACFPVQLDTLSDGASVDESH ENSCPOP00000019666/1-832 SANEQDNNLLEQYLTSVQQLDDADERTNFDQVTGDSKLYLACSSEKLDTLSDRASIDKTH XP_004858050.1/1-911 SANEQDNNLLEQYLTSVQQLEDADERTNFDAVTGDSELCLACSLEKLDTLSDRASVDETH * .****.**:***:*****:** : :. * : *.: :** ::.: ** .::* ENSMUSP00000023270/1-856 RVASTSQDEISQTPENCQLNEEAQGQPPECDPAFQGLHVGVTVQPV ENSRNOP00000002191/1-845 RASPTLQEEISQTPENCKLNEEVQGQPPECDTAFQVLQVGVTV--- ENSP00000325881/1-891 GISPPLQGEISQTQENSKLNAEVQGQQPECDSTFQLLHVGVTV--- ENSCPOP00000019666/1-832 GTSSASLDEIRLTPENCKLNEDVQGQQPDCDSAFEVLHVGVTV--- XP_004858050.1/1-911 GISPTLQDEIRQTPESYKLNAEVQGQQPECDSTFQVLHVGVTV--- :.. ** * *. :** :.*** *:**.:*: *:*****