CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000107787/1-1050 MV--------------FSMWTRKRQILIFLNMLLVSRVFGFRWFPKTLPCEVKVNIPEAH ENSRNOP00000005620/1-1050 MV--------------FPMWTLKRQSFIFLNMILVSRVLGFRWYPKTLPCDVSLDSTNTH ENSP00000370034/1-1049 MV--------------FPMWTLKRQILILFNIILISKLLGARWFPKTLPCDVTLDVPKNH ENSCPOP00000019618/1-869 -----------------------------------------------------------H XP_004871092.1/1-1063 MVKPPSKAGLVECNMGFPTWTLKRQFLILLGMMLISRLLGARWFPKTLPCDISLDPSKTH * ENSMUSP00000107787/1-1050 VIVDCTDKHLTEIPEGIPTNTTNLTLTINHIPSISPDSFRRLNHLEEIDLRCNCVPVLLG ENSRNOP00000005620/1-1050 VIVDCTDKHLTEIPEGIPTNTTNLTLTINHIPSISPDSFHRLKHLEELDLRCNCVPILLG ENSP00000370034/1-1049 VIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVPIPLG ENSCPOP00000019618/1-869 VIVDCTDKHLKEIPEGIPTNVTNLTLTINHIPSISPDSFHNLDHLIEVDFRCNCIPIRTG XP_004871092.1/1-1063 VIVDCTDKHLTEIPEGIPTNATNLTLTINHIPSISPDSFHNLDHLIEVDFRCNCVPIRMG **********.*** *****.***********.*** **:.*.** *:*:****:*: * ENSMUSP00000107787/1-1050 SKANVCTKRLQIRPGSFSGLSDLKALYLDGNQLLEIPQDLPSSLHLLSLEANNIFSITKE ENSRNOP00000005620/1-1050 SKANVCTKRLQIRPGSFSGLSDLKSLYLDGNQLLEIPQDLPSSLQLLSLEANNIFSITKE ENSP00000370034/1-1049 SKNNMCIKRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPSLQLLSLEANNIFSIRKE ENSCPOP00000019618/1-869 PKNN----------------------------------DLPPSLQLLSLEANNIFFIKKE XP_004871092.1/1-1063 AKKNMCVRRLQIKPRSFSRLTYLKSLYLDGNQLLEIPQDLPPSLQLLSLEANNIFVIMKE .* * .**.**:********** * ** ENSMUSP00000107787/1-1050 NLTELVNIETLYLGQNCYYRNPCNVSYSIEKDAFLVMRNLKVLSLKDNNVTAVPTTLPPN ENSRNOP00000005620/1-1050 NLSELVNIESLYLGQNCYYRNPCNVSYSIEKDAFLVMKNLKVLSLKDNNVTAVPTILPPN ENSP00000370034/1-1049 NLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTAVPTVLPST ENSCPOP00000019618/1-869 NLTELINIEMLYLGQNCYYRNPCNVSYSVEKNAFLNLRNLKVLSLKSNNITAVPIVLPSN XP_004871092.1/1-1063 NLTELVNIEMLFLGQNCYYRNPCNVSYSIEKNAFLNLRNLKVLSLKDNNITAVPTLLPSN **:** *** *:*********** ****:**:*** : :*******.**:**** **.. ENSMUSP00000107787/1-1050 LLELYLYNNIIKKIQENDFNNLNELQVLDLSGNCPRCYNVPYPCTPCENNSPLQIHDNAF ENSRNOP00000005620/1-1050 LLELYLYNNIIKRIQEHDFNKLSQLQVLDLSGNCPRCYNVPYPCTPCENNSPLQIHDNAF ENSP00000370034/1-1049 LTELYLYNNMIAKIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCAPCKNNSPLQIPVNAF ENSCPOP00000019618/1-869 LTELYLHNNIITNIQEDDFSNLNQLQILDLSGNCPRCYNVPFPCTPCENNSPLQIHIKAF XP_004871092.1/1-1063 LTELYLYNNIITNIQEDDFNNLNQLEILDLSGNCPRCYNVPFPCIPCENNSPLQIHVNAF * ****:**:* .***.**.:*.:*::************.*:** **:******* :** ENSMUSP00000107787/1-1050 NSLTELKVLRLHSNSLQHVPPTWFKNMRNLQELDLSQNYLAREIEEAKFLHFLPNLVELD ENSRNOP00000005620/1-1050 DSLTELKVLRLHSNSLQHVPAEWFKNMSNLQELDLSQNYLAREIEEAKFLNSLPNLVQLD ENSP00000370034/1-1049 DALTELKVLRLHSNSLQHVPPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLD ENSCPOP00000019618/1-869 DALTELQILRLHSNSLQHVPARWFKNMKNLKDLDLSQNYLAREIGDAKFLQFLPNLIGLD XP_004871092.1/1-1063 DALTELQVLRLHSNSLQHVPVRWFKNMKNLRELDLSQNYLAKEIGDAKFLHLLPNLIQLD ::****::************ ****: :*::******:**:** :****: **.*: ** ENSMUSP00000107787/1-1050 FSFNYELQVYHASITLPHSLSSLENLKILRVKGYVFKELKNSSLSVLHKLPRLEVLDLGT ENSRNOP00000005620/1-1050 LSFNYELQVYHASITLPHSLSSLTKLKNLYIKGYVFKELKDSSLSVLHNLSNLEVLDLGT ENSP00000370034/1-1049 LSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGT ENSCPOP00000019618/1-869 LSFNYELQVYHTFINLSYSFSSLKKLKILRIKGYVFKELTSHNLLPLRDLHNLEVLDLGT XP_004871092.1/1-1063 LSFNYELQVYHAFINLSHSFSSLKNLKILRIKGYVFKELRYLNLSPLHDLHNLEVLDLGT :***:*****:: :.*. ::*** .** * ::******* .* *:.* .******** ENSMUSP00000107787/1-1050 NFIKIADLNIFKHFENLKLIDLSVNKISPSEESREVGFCPNAQTSVDRHGPQVLEALHYF ENSRNOP00000005620/1-1050 NFIKIADLNIFQQFENLKFIDLSVNKISPSEESREVGLCPNAQTSVDWHGPQVLEALHYF ENSP00000370034/1-1049 NFIKIANLSMFKQFKRLKVIDLSVNKISPSGDSSEVGFCSNARTSVESYEPQVLEQLHYF ENSCPOP00000019618/1-869 NFIKIANLSIFQQFQNLKVIDLS-----------------NTITSVEGYTPRIFETLHYF XP_004871092.1/1-1063 NFIKIANLSIFKQFQKLKFIDLSMNKISPSEDSSEIGFCSNTRTSVESNGPQVLETLHYF ******:*.:*::*:.**.**** *: ***: *:::* **** ENSMUSP00000107787/1-1050 RYDEYARSCRFKNKEPPSFLPLNADCHIYGQTLDLSRNNIFFIKPSDFQHLSFLKCLNLS ENSRNOP00000005620/1-1050 RYDEYARSCRFKNKEPPTFLPLNADCHTYGKTLDLSRNNIFFIKPSDFKHLSFLKCLNLS ENSP00000370034/1-1049 RYDKYARSCRFKNKEAS-FMSVNESCYKYGQTLDLSKNSIFFVKSSDFQHLSFLKCLNLS ENSCPOP00000019618/1-869 RY---------------------------GQTLDLSRNNIFFVKPSDFQHLSFLKCLNLS XP_004871092.1/1-1063 RYDKYARSCRFKNMETP-FLTFNNDCNMYGQTLDLSRNNIFFVKPSDFQHLSFLKCLNLS ** *:*****:*.***:*.***:*********** ENSMUSP00000107787/1-1050 GNTIGQTLNGSELWPLRELRYLDFSNNRLDLLYSTAFEELQSLEVLDLSSNSHYFQAEGI ENSRNOP00000005620/1-1050 GNAIGQTLNGSELQPLRELRYLDFSNNRLDLLYSTAFEELQNLEILDLSSNSHYFQAEGI ENSP00000370034/1-1049 GNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELHKLEVLDISSNSHYFQSEGI ENSCPOP00000019618/1-869 GNAIGQTLTGSEFQHLKQLKYLDYSNNRLDLLHSTAFEALRNLEVLDLSSNSHYFQSEGI XP_004871092.1/1-1063 GNTIGQTLNGSEFQHLEQLKYLDFSNNRLDLLHSTAFEELHNLEVLDLSMNSHYFQSEGI ** *.***.***: * :*:***:********:***** *:.**:**:* ******:*** ENSMUSP00000107787/1-1050 THMLNFTKKLRLLDKLMMNDNDISTSASRTMESDSLRILEFRGNHLDVLWRAGDNRYLDF ENSRNOP00000005620/1-1050 THMLNFTKKLRHLEKLMMNDNDISTSASRTMESESLRVLEFRGNHLDVLWRDGDNRYLDF ENSP00000370034/1-1049 THMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWREGDNRYLQL ENSCPOP00000019618/1-869 THMLNFTKNLKFLKKLMMNDNDISTSTSRTMESESLKILEFRGNHLDILWRDGDNRYLKF XP_004871092.1/1-1063 THMLNFTKNLKFLKKLMMNDNDISTSTSRTMESKSLKILEFRGNHLDILWRDGDNRYLKF ********:*: *.**********:*:******.**: *********:*** ******.: ENSMUSP00000107787/1-1050 FKNLFNLEVLDISRNSLNSLPPEVFEGMPPNLKNLSLAKNGLKSFFWDRLQLLKHLEILD ENSRNOP00000005620/1-1050 FKNLLNLEELDISRNSLNSVPPGVFEGMPPNLTTLSLAKNGLRSFSWGRLQLLKHLKNLD ENSP00000370034/1-1049 FKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLKNLETLD ENSCPOP00000019618/1-869 FKNLL-------------------------NLKNLSLAKNGLKSFNWGKLSLLKNLEILD XP_004871092.1/1-1063 FKNLLNLEELDISRNSLSFLPPGVFDGMPPNLKTLSLAKNGLQTFNWRKLSFLKNLEILD ****: **..********::* * :*. **:*: ** ENSMUSP00000107787/1-1050 LSHNQLTKVPERLANCSKSLTTLILKHNQIRQLTKYFLEDALQLRYLDISSNKIQVIQKT ENSRNOP00000005620/1-1050 LSHNQLTTVPARLANCSKSLTKLILNHNQIRQLTKYFLEDALQLRYLDISSNKIQVIQKT ENSP00000370034/1-1049 LSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKT ENSCPOP00000019618/1-869 LGHNQLTTLPDRLSNCSRSLKKLILMKNQIRYLTKHFLEDAFQLRYLDLSSNR------- XP_004871092.1/1-1063 LSHNQLTTLPERLSNCSRSLKKLILMKNQIRHLTKYFLKDAFQLRYLDLSSNKIQVIQKT *.*****.:* **:***:**..*** :**** ***:**:**:******:***: ENSMUSP00000107787/1-1050 SFPENVLNNLEMLVLHHNRFLCNCDAVWFVWWVNHTDVTIPYLATDVTCVGPGAHKGQSV ENSRNOP00000005620/1-1050 SFPENVLNNLNMLLLHHNRFLCNCDAVWFVWWVNHTDVTIPYLATDVTCAGPGAHKGQSV ENSP00000370034/1-1049 SFPENVLNNLKMLLLHHNRFLCTCDAVWFVWWVNHTEVTIPYLATDVTCVGPGAHKGQSV ENSCPOP00000019618/1-869 -----------------NRFLCNCDAVWFVWWVNHTEVTIPYLATEVTCMGPGAHKGQSV XP_004871092.1/1-1063 SFPQNVLNNLEMLLLHRNRFLCNCDAVWFVWWVNHTDVTIPYLATEVTCVGPGAHKGQSV *****.*************:********:*** ********** ENSMUSP00000107787/1-1050 ISLDLYTCELDLTNLILFSVSISSVLFLMVVMTTSHLFFWDMWYIYYFWKAKIKGYQHLQ ENSRNOP00000005620/1-1050 ISLDLYTCELDLTNLILFSVSISSVLFLMIVMTTSHLFFWDMWYIYYFWKAKIKGYQHLQ ENSP00000370034/1-1049 ISLDLYTCELDLTNLILFSLSISVSLFLMVMMTASHLYFWDVWYIYHFCKAKIKGYQRLI ENSCPOP00000019618/1-869 VSLDLYTCELDLTNLILFSFSISVALFLMVVMTASHLYFWDMWYIYHFCKAKIRGYQRLR XP_004871092.1/1-1063 VSLDLYTCELNLINLILFSVSISVALFLMVVMTASHLYFWDMWYIYHFFKAKLRGYQRLR :*********:* ******.*** ****::**:***:***:****:* ***::***:* ENSMUSP00000107787/1-1050 SMESCYDAFIVYDTKNSAVTEWVLQELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQ ENSRNOP00000005620/1-1050 SMESCYDAFIVYDTKNSAVTEWVLQELVVKLEDPREKHFNLCLEERDWLPGQPVLENLSQ ENSP00000370034/1-1049 SPDCCYDAFIVYDTKDPAVTEWVLAELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQ ENSCPOP00000019618/1-869 SAECCYDAFIVYDTNDPAVTEWVLDELVARLEDPREKHFNLCLEERDWLPGQPVLENLSQ XP_004871092.1/1-1063 SAECCYDAFIVYDTKDPAVTEWVLDELVARLEDPREKHFNLCLEERDWLPGQPVLENLSQ * :.**********::.******* ***.:****************************** ENSMUSP00000107787/1-1050 SIQLSKKTVFVMTQKYAKTESFKMAFYLSHQRLLDEKVDVIILIFLEKPLQKSKFLQLRK ENSRNOP00000005620/1-1050 SIQLSRKTVFVMTQKYAKTESFKMAFYLSHQRLMDEKVDVIILIFLEKPLQKSKFLQLRK ENSP00000370034/1-1049 SIQLSKKTVFVMTDKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPFQKSKFLQLRK ENSCPOP00000019618/1-869 SIQLSKKTVFVMTEKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPLKKSKFLQLRK XP_004871092.1/1-1063 SIQLSKKTVFVMTEKYAKTENFKIAFYLSHQRLMDEKVDVIILIFLEKPFTKSKFLQLRK *****:*******:******.**:*********:***************: ********* ENSMUSP00000107787/1-1050 RLCRSSVLEWPANPQAHPYFWQCLKNALTTDNHVAYSQMFKETV ENSRNOP00000005620/1-1050 RLCSSSVLEWPTNPQAHPYFWQCLKNALTTDNHVAYSQMFKETV ENSP00000370034/1-1049 RLCGSSVLEWPTNPQAHPYFWQCLKNALATDNHVAYSQVFKETV ENSCPOP00000019618/1-869 RLCGSSVLEWPTNPQAHLYFWQCLKNALAMDNHVA--------- XP_004871092.1/1-1063 RLCGSSVLEWPTNPQAHPYFWQCLKNALAMDNHVVYSQMFKETV *** *******:***** **********: ****.