CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000107415/1-1252 MNRPL--SAEAEEELEWQVASRRRKAWAKCRSSWQASETEDLSTETTTQDEDEDDEEDLP ENSRNOP00000008046/1-1255 MNRPL--SAEAEEELEWQVASRRRKAWAKCRSSWQASETEDLSTETTTQDEDEDDEEDLP ENSP00000388731/1-1259 MDRPLSSSAEAEEELEWQVASRRRKAWAKCRSSWQASETEDLSTEATTQDEEEDEEEDLP ENSCPOP00000019370/1-1188 ----------------------------------------------------------LP XP_004868224.1/1-1254 MNRPLTASAEAEEELEWQVAIRRRKAWAKCRSSWQASETEDLSTEATTQDEDDDDE-DLS *. ENSMUSP00000107415/1-1252 GTKLPAPAGRGNVPNEKIAIWLKDCRTPLGASLDEQSSGTPKGVLVRNGGSFEDDLSLGA ENSRNOP00000008046/1-1255 GAKLPAAAGRGNVPNEKIAIWLKDCRTPLGASLDEQSSVGPKGVLLRNGGSFEDDLSLGA ENSP00000388731/1-1259 GAQLPAAGGRGNVPNEKIAIWLKDCRTPLGASLDEQSSSTLKGVLVRNGGSFEDDLSLGA ENSCPOP00000019370/1-1188 GAKLPAAAGRGNVPNEKIAIWLKDCRTPLGASLDEQSGSTLKGVLVRNGGSFEDDLSLGA XP_004868224.1/1-1254 GAKLPAASGRGNVPNEKIAIWLKDCRTPLGASLDEQSSSTPKGVLVRNGGSFEDDLSLGA *::***..*****************************. ****:************** ENSMUSP00000107415/1-1252 EANHLHEPDAQVENCNNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDP ENSRNOP00000008046/1-1255 EANHLHEPDAQVENCNNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDP ENSP00000388731/1-1259 EANHLHESDAQIENCNNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDP ENSCPOP00000019370/1-1188 EANHLHENNAQIENCSNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDP XP_004868224.1/1-1254 EANHLHGSSAQIENCSNILAKERRLQFHQKGRSMNSTGSGKSSGTVSSVSELLELYEEDP ****** .**:***.******************************************** ENSMUSP00000107415/1-1252 EEILYNLGFGRDEPDIASKIPSRFFNSSSFARGIDIKVFLSAQMQRMEVENPNYALTSRF ENSRNOP00000008046/1-1255 EEILYNLGFGRDEPDIASKIPSRFFNSSSFARGIDIKVFLSAQMQRMEVENPNYALTSRF ENSP00000388731/1-1259 EEILYNLGFGRDEPDIASKIPSRFFNSSSFAKGIDIKVFLSAQMQRMEVENPNYALTSRF ENSCPOP00000019370/1-1188 EEILYNLGFGRDEPDIASKIPSRFFNSSSFARGIDIKVFLSAQMQRMEVENPNYALTSRF XP_004868224.1/1-1254 EEILYNLGFGRDEPDIASKIPSRFFNSSSFARGIDIKVFLSAQMQRMEVENPNYALTSRF *******************************:**************************** ENSMUSP00000107415/1-1252 RQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSTKEVADSPPPLTRSNTANRLMKTL ENSRNOP00000008046/1-1255 RQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSTKEAADCPPPLTRSNTANRLMKTL ENSP00000388731/1-1259 RQIEVLTTVANAFSSLYSQVSGTPLQRIGSMSSVTSNKE-TDPPPPLTRSNTANRLMKTL ENSCPOP00000019370/1-1188 RQIEVLTTVANAFSSLYSQVSGTPLQRIGSISSVASTKE-TDTPPPLTRSNTANRLIKTL XP_004868224.1/1-1254 RQIEVLTTVANAFSSLYSQVSGTPLQRIGSISSVASTKE-TDAPPPLTRSNTANRLMKTL ******************************:***:*.** :* *************:*** ENSMUSP00000107415/1-1252 SKLNLCVDKTEKGEG-GSSPATEKGRTLSISLSEDGGGGKSDPKLQKVVKKKESSSMLAT ENSRNOP00000008046/1-1255 SKLNLCVDKTEKAEG-SSTPAAEKGRSLSVSLSEDGGGGKSDPKPQKVIKKKESSSMLAT ENSP00000388731/1-1259 SKLNLCVDKTEKGESSSPSPSAEKGKILNVSVIEE-SGNKNDQKSQKIMKKKESSSMLAT ENSCPOP00000019370/1-1188 SKLNLCVDKAEKGEG-SSPPGVEKGKIFNVALVEE-SGNKNDQKSQKV-KKKDSSSVLAT XP_004868224.1/1-1254 SKLNLCVDKAEKGEGSSSSPATEKGKILSVSLMEE-SGNKNDQKSQKVLKKKDSSSVLAT *********:**.*. ...*..***: :.::: *: .*.*.* * **: ***:***:*** ENSMUSP00000107415/1-1252 VTEEVSGSSSTVTDSVDADRLSEEADSTISHQEESEESREAHSQEKDPLRKSAVTDPDLG ENSRNOP00000008046/1-1255 VTEEVSGSSSTITDSIDADRLSDEAESNISHKVESEENGEAHSQN-DALRQSAVTDPDFG ENSP00000388731/1-1259 VKEEVSGSSAAVTENADSDRISDEANSNFNQGTENEQSKETQSHESKLGEESGIVESKLD ENSCPOP00000019370/1-1188 VKEEVSGSSAPSKEGADPGRLSDEANRNFSQETDSEQSNKTQNHE-----ESGIVEPHIA XP_004868224.1/1-1254 VKEEVSGSSAPATESADRGKLLDEANCNFNQESDSGQSKETQNHESKLYKESGIIESDLG *.*******:. .:. * .:: :**: .:.: :. :. :::.:: :*.: :..: ENSMUSP00000107415/1-1252 HD-GRVSSHCELESSSELKSAQASSSEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEG ENSRNOP00000008046/1-1255 HDGGSMSSLCELESSSELKSAQASSSEKEPCATLTIPSIRNIMVQQKDSFEMEEVQSTEG ENSP00000388731/1-1259 SD-FNISSHSELENSSELKSVHISTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEG ENSCPOP00000019370/1-1188 SD-FSVSSPSQLEDSSDLKHIHVSTPEKEPCAPLTIPSIRNIMTQQKDSFEMEEVQSTEG XP_004868224.1/1-1254 SD-FNVSSQGELEN-SDLKHIPVSTPEKEPCAPLAIPSIRNVMTQQKDSFEMEEVQSTEG * :** :**. *:** *:.******.*:******:*.**************** ENSMUSP00000107415/1-1252 EAPHVPATCQLSLAKSKRDHLLRTASQHSDSSGFAEDSTDCVSLNHLLVNESLQAMGSSA ENSRNOP00000008046/1-1255 EAPHVPATCQLSLAKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVHESLQAMGSSA ENSP00000388731/1-1259 EAPHVPATYQLGLTKSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVQESLQAMGSSA ENSCPOP00000019370/1-1188 EAPHVPATYQLGLTKSKREHLLRTTSQHSDSSGFAEDSTDCFSLNHLQVHEPLQAMGSSA XP_004868224.1/1-1254 EAPHVPASYQLGLTRSKRDHLLRTASQHSDSSGFAEDSTDCLSLNHLQVHEPLQAMGSSA *******: **.*::***:*****:****************.***** *:*.******** ENSMUSP00000107415/1-1252 DSCDSETTVTSLGEDHVTPTAQDQPYFNESEEESLAPLQKGRAKVEIVAEKRKADNQDFP ENSRNOP00000008046/1-1255 DSCDSETTVTSLGEDHVTPTAPDQPYFNESEEESLASLQKGRAKV-IVAEKRKADNQDFP ENSP00000388731/1-1259 DSCDSETTVTSLGEDLATPTAQDQPYFNESEEESLVPLQKGLEKAAAVADKRKSGSQDFP ENSCPOP00000019370/1-1188 DSCDSEMTVTSFGEDLVTPTTQEQPYFNESEEELPNPLQKEREKAAAAADNRESDSQDSP XP_004868224.1/1-1254 DSCDSETTVTSFGEDLVTPTPQDQPYFNESEEELPN--------TAAVSDKRKPDSQGFP ****** ****:*** .***. :********** . .:::*:...*. * ENSMUSP00000107415/1-1252 QCVTAENAGNNESTKGPCEPGHQITET--GEHPPLAATGELPREESVESDVEKGSECEFA ENSRNOP00000008046/1-1255 HCATAENAGNNESVKGPCEPGPQITETETEEEPPLAATGELLREGSGESDMDKGSECEFA ENSP00000388731/1-1259 QCNTIENTGTKQSTCSPGDHIIEITEVEEDLFP--AETVELLREASAESDVGKSSESEFT ENSCPOP00000019370/1-1188 QCEPEESVRHQPSSCPPGDPVTEAAEVEQGSAS--APTVEPLREASIESDVDRSSECEFP XP_004868224.1/1-1254 QCRPEESAGHEPPSHSPGDRVAEVSEVEEGSSP--AQSVELLREASGESDVDRSSECEFP :* . *.. : . * : : :*. . * : * ** * ***: :.**.**. ENSMUSP00000107415/1-1252 QYTTHHILRSLASF-EAQGSGMSSEKKTGFPSSVDRVNTALQRAQMKVCSMSGQRVGRSL ENSRNOP00000008046/1-1255 QYTTHHILRSLTSFEEAQGSGMSSKKKTEFPSSVDRVNTALQRAQMKVCSMSGQRVGRSL ENSP00000388731/1-1259 QYTTHHILKSLASI-EAKCSDMSSENTTGPPSSMDRVNTALQRAQMKVCSLSNQRMGRSL ENSCPOP00000019370/1-1188 QYNTHHISQSLASI-EAQCSDLRPENTSGPLSSVDRVNTALQRAQMKVCSLSNQRVGRSL XP_004868224.1/1-1254 QYTTHHIPKSLASI-EAKCSDLSSESTMRPPSSVDRVNTALQRAQMKVCSLSNQRVGRSL **.**** :**:*: **: *.: .:.. **:****************:*.**:**** ENSMUSP00000107415/1-1252 IKSKDLLKQRYLLAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYK ENSRNOP00000008046/1-1255 IKSKDLLKQRYFLAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYK ENSP00000388731/1-1259 LKSKDLLKQRYLFAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYK ENSCPOP00000019370/1-1188 IKSKDL----YLLAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYK XP_004868224.1/1-1254 IKSKDLLKQRYLLAKAGYPLRRSQSLPTTLLSPVRVVSSVNVRLSPGKETRCSPPSFTYK :***** *::*********************************************** ENSMUSP00000107415/1-1252 YTPEEEQDLEKQGTE---------HDGQSLVKSTIFIPPPSVKK-EEAPQSEGTRLEECH ENSRNOP00000008046/1-1255 YTPEEEQELEKQVTE---------HDGQSLVKSTIFIPPSSVKK-EEAPQSEGTRLEECH ENSP00000388731/1-1259 YTPEEEQELEKRVME---------HDGQSLVKSTIFISPSSVKK-EEAPQSEAPRVEECH ENSCPOP00000019370/1-1188 YTPEEQQELDKESTA---------PDGQSLVKSTIFISPSSEKKDEETSRGEASQVEECH XP_004868224.1/1-1254 YTPEEEQELEKGAEEQELEKGAAAPDSQSLVKSTIFISPAPAKKDEEASPSDVAQLEERR *****:*:*:* *.**********.*.. ** **:. .: .::** : ENSMUSP00000107415/1-1252 HGRLAPCPQFAP--ISQSTCSLHSVHSEWQDRPLCEHMRTLSAHSVPNISGAACSAF-SP ENSRNOP00000008046/1-1255 HGRLAPCPQFAP--ISQSTCSLHSVHSEWQDRPLCEHMRTLSAHSVPNISGAACSAFSSP ENSP00000388731/1-1259 HGRTPTCSRLAPPPMSQSTCSLHSIHSEWQERPLCEHTRTLSTHSVPNISGATCSAFASP ENSCPOP00000019370/1-1188 HGRTPVCPQFAPERISQSTCSLHTLH-EWHDRPLCEHMRTLSTHSVPNIPGATCSAFLSP XP_004868224.1/1-1254 HGRTPVCSHLAPPPISQSTCSLHTLH-EWQDRPLCEHMRTLSAHSVPSIPGATCSAFTSP *** . *.::** :********::* **::****** ****:****.*.**:**** ** ENSMUSP00000107415/1-1252 FGCPYSHRHAAHPYRACSVNPPSAIEMQLRRVLHDIRSSLQNLSQYPMTRGPDLAAAPYS ENSRNOP00000008046/1-1255 FGCPYSHRHAAHPCRPCPVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMTRGPDLAAAPYS ENSP00000388731/1-1259 FGCPYSHRHATYPYRVCSVNPPSAIEMQLRRVLHDIRNSLQNLSQYPMMRGPDPAAAPYS ENSCPOP00000019370/1-1188 LGCPYSHRHAAYPCRAAAVNPPSAIEMQLRRVLHHIRNSLQNLSQYSV-RGPDLAAAPYS XP_004868224.1/1-1254 LGCPYSHSHAAYLYRACSGNPPSAIEMQLRRVLHHIRNSLQNLSQSPMMRGADLAAVPYS :****** **:: * .. ***************.**.******* .: **.* **.*** ENSMUSP00000107415/1-1252 TQNSSVLPLYENTFQELQVVRRSLNLFRTQMMDLELAMLRQQTVVYPHMTEEDRYEVDQL ENSRNOP00000008046/1-1255 TQKSSVLPLYENTFQELQVVRRSLNLFRTQMMDLELAMLRQQTVVYPHMTEEDRYEVDQL ENSP00000388731/1-1259 TQKSSVLPLYENTFQELQVMRRSLNLFRTQMMDLELAMLRQQTMVYHHMTEEERFEVDQL ENSCPOP00000019370/1-1188 TQKSSVLPLYENTFQELQVMRRSLNLFRTQMMDLELAMLRQQTV-YHHMTEEERYEVDQL XP_004868224.1/1-1254 TQKSSVLPLYE----ELQVMRRSLNLFRTQMMDLELAMLREQTLVYQHMTEEERYEVDQL **:******** ****:********************:**: * *****:*:***** ENSMUSP00000107415/1-1252 QGLRNSVRMELQDLEMQLEERLLGLDEQLRAVRVPSPFRPSALPGMCGSRSVDNLSCPSP ENSRNOP00000008046/1-1255 QGLRNSVRMELQDLELQLEERLLGLDEQLRAVRVPSPFRSSALPGMCGSRSADNLSCPSP ENSP00000388731/1-1259 QGLRNSVRMELQDLELQLEERLLGLEEQLRAVRMPSPFRSSALMGMCGSRSADNLSCPSP ENSCPOP00000019370/1-1188 QSLRNSVRVELQELELQLEERLLDLEEQLRAVQVPSPFHSSSLMGMCGSRSADNLSCPSP XP_004868224.1/1-1254 QSLRNSVRMELQDLELQLEERLLGLDEQLQAVRVPSPF-SSSLLGMCGSRSADNLSCPSP *.******:***:**:*******.*:***:**::**** .*:* *******.******** ENSMUSP00000107415/1-1252 LNVMEPVTELIREQSYLKSELGLGLGDMAYEIPPGESSESVFSQATSESSSVCSSPS-HT ENSRNOP00000008046/1-1255 LNVMEPVTELMREQSYLKSELGLSLGDMGYEIPPGESSESVFSQATSESSSVCSSPS-HT ENSP00000388731/1-1259 LNVMEPVTELMQEQSYLKSELGLGLGEMGFEIPPGESSESVFSQATSESSSVCSGPS-HA ENSCPOP00000019370/1-1188 LNVMEPVAELMREQSYLKSELGLGLGEMGFEIPAGESSESVFSQATSESSSVCSSPSHHA XP_004868224.1/1-1254 LNVMEPVAELMREQSYLKSELGLGLGEMGFEIPPGESSESVFSRATSESSSACSSPSHHI *******:**::***********.**:*.:***.*********:*******.**.** * ENSMUSP00000107415/1-1252 NRRS---RGLPGSKPRARLVARKKIFRASVALTPTAPSRTGSVQTPPDLESSEEAGGAEE ENSRNOP00000008046/1-1255 NRRS---RGPSGSKPRARLVARKKIFRASVALTPTAPSRTGSVQTPPDLESSEEAGAAEE ENSP00000388731/1-1259 NRRTGVPSTASVGKSKTPLVARKKVFRASVALTPTAPSRTGSVQTPPDLESSEEVDAAEG ENSCPOP00000019370/1-1188 SRRAAV-PGQTGGKRTAQSVARKKVFRASVALTPTAPSRTGSVQTPPELESSEEAGVAEE XP_004868224.1/1-1254 SRRTAVPPGDARGKRKAQSGAGKKVFRASVALTPTAPSRTGSLQTPPELESSEEVGTAAE .**: . .* : * **:*****************:****:******.. * ENSMUSP00000107415/1-1252 ASPVVGLASHVEEEPEDLSLMPAAEEMHRNVEQDELQQVIREIKESIVGEIRREIVSGLL ENSRNOP00000008046/1-1255 ASQVVGLTSHVEEEPEDLSLMPTAEEMHRNVEQDELQQVIREIKESIVGEIRREIVSGLL ENSP00000388731/1-1259 APEVVGPKSEVEEGHGKLPSMPAAEEMHKNVEQDELQQVIREIKESIVGEIRREIVSGLL ENSCPOP00000019370/1-1188 GVRVVGPNSDMEEECAKLSVMPAAEEMQRSVEQNELQQVIREIKESIVGEIRREIVSGLL XP_004868224.1/1-1254 GARVAGPNSDMEEECGKLSAMPAAEEMQRNVEQDELQQVIREIKESIVGEIRREIVSGLL . *.* *.:** .*. **:****::.***:************************** ENSMUSP00000107415/1-1252 AAVSSSKAPGPKQDSH ENSRNOP00000008046/1-1255 AAVSSSKASASKQDSH ENSP00000388731/1-1259 AAVSSSKASNSKQDYH ENSCPOP00000019370/1-1188 AAVSSNKASNSKHDSH XP_004868224.1/1-1254 AAVSSNKASSSKQDSH *****.**. .*:* *