CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000025912/1-1234 MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDPNGFFLYWTGPNME ENSRNOP00000028720/1-1236 MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDPNGFFLYWTGPNME ENSP00000279230/1-1234 MAGAQPGVHALQLEPPTVVETLRRGSKFIKWDEETSSRNLVTLRVDPNGFFLYWTGPNME ENSCPOP00000019282/1-1216 MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEETSSRNLVTLRVDSHGFFLYWTGPNME XP_004852581.1/1-1223 MAGARPGVHALQLEPATVVETLRRGSKFIKWDEETSSRNLVTLRVDPNGFFLYWTGPNME ****:**********.******************:***********.:************ ENSMUSP00000025912/1-1234 VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFLNF ENSRNOP00000028720/1-1236 VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFLNF ENSP00000279230/1-1234 VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVSGPDPVNTVFLNF ENSCPOP00000019282/1-1216 VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTTFLNF XP_004852581.1/1-1223 VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFLNF ************************************:**********:*******.**** ENSMUSP00000025912/1-1234 MAVQDDTVKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS ENSRNOP00000028720/1-1236 MAVQDDTVKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS ENSP00000279230/1-1234 MAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS ENSCPOP00000019282/1-1216 MAVQDDTVKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS XP_004852581.1/1-1223 MAVQDDTIKVWSEELFKLAMNILGQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS ******* ***************.************************************ ENSMUSP00000025912/1-1234 ADKKRVETALESCGLNFNRSESIRPDEFPLEIFERFLNKLCLRPDIDKILLEIGAKGKPY ENSRNOP00000028720/1-1236 ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY ENSP00000279230/1-1234 ADKKRVETALESCGLKFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY ENSCPOP00000019282/1-1216 ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY XP_004852581.1/1-1223 ADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPY ***************:************.******************************* ENSMUSP00000025912/1-1234 LTLEQLMDFINQKQRDPRLNEVLYPPLRSSQARLLIEKYETNKQFLERDQMSMEGFSRYL ENSRNOP00000028720/1-1236 LTLEQLMDFINQKQRDPRLNEVLYPPLRSSQARLLIEKYEPNKQFLERDQMSMEGFSRYL ENSP00000279230/1-1234 LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYL ENSCPOP00000019282/1-1216 LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYL XP_004852581.1/1-1223 LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKYEPNQQFLERDQMSMEGFSRYL ****************************.***********.*:***************** ENSMUSP00000025912/1-1234 GGEENGILPLEALDLSMDMTQPLSAYFINSSHNTYLTAGQLAGPSSVEMYRQALLWGCRC ENSRNOP00000028720/1-1236 GGEENGILPLEALDLSMDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC ENSP00000279230/1-1234 GGEENGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC ENSCPOP00000019282/1-1216 GGEENGILPLEALDLSMDMTQPLSAYFINSSHNTYLTAGQLAGASSVEMYRQVLLWGCRC XP_004852581.1/1-1223 GGEENGILPLEALDLSMDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRC **************** **************************.********.******* ENSMUSP00000025912/1-1234 VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAEAAFKTSPYPVILSFENHVDSAK ENSRNOP00000028720/1-1236 VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK ENSP00000279230/1-1234 VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK ENSCPOP00000019282/1-1216 VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAESAFKTSPYPVILSFENHVDSAK XP_004852581.1/1-1223 VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAK **************************************:********************* ENSMUSP00000025912/1-1234 QQAKMAEYCRSIFGDALLIDPLDKYPLSAGIPLPSPQDLMGRILVKNKKRHRPSTGVPDS ENSRNOP00000028720/1-1236 QQAKMAEYCRSIFGEALLIDPLDKYPLSAGTPLPSPQDLMGRILVKNKKRHRPSTGVPDS ENSP00000279230/1-1234 QQAKMAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQDLMGRILVKNKKRHRPSAGGPDS ENSCPOP00000019282/1-1216 QQAKMAEYCRSIFGDALLIDPLDKYPLAAGTSLPSPQELMGRILVKNKKRHRPSTGLPDS XP_004852581.1/1-1223 QQAKMAEYCRSIFGDALLIDPLDKYPLASGIPLPSPQELMGRILVKNKKRHRPST---TY **************:****:*******:.* .*****:****************: ENSMUSP00000025912/1-1234 SVRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKTSLEPQKSLGE ENSRNOP00000028720/1-1236 SVRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKTSLEPQKSLGE ENSP00000279230/1-1234 AGRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKPSLEPQKSLGD ENSCPOP00000019282/1-1216 GVRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPALSNGEEVGLEKPSLEPRKSLGE XP_004852581.1/1-1223 SVRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKPSLEPRKSLGE . ***********************************.***********.****:****: ENSMUSP00000025912/1-1234 ESLSREPNVPMPDRDREDEEEDEEEEETTDPKKPTTDEGTASSEVNATEEMSTLVNYVEP ENSRNOP00000028720/1-1236 EGLNRGPNVLMPDRDREDEEEDEEEEETTDPKKPTTDEGTASSEVNATEEMSTLVNYVEP ENSP00000279230/1-1234 EGLNRGPYVLGPA-DREDEEEDEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYIEP ENSCPOP00000019282/1-1216 ESLNRGSDVLGPA-D-----------QPTDPKKPTTDEGTASSEVNATEEMSTLVNYIEP XP_004852581.1/1-1223 ESLNRGSDVLGPA-DREEEDEEEEEEEQTDPKKPTTDEGTASSEVNATEEMSTLVNYVEP *.*.* . * * * : *****************************:** ENSMUSP00000025912/1-1234 VKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNY ENSRNOP00000028720/1-1236 VKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNY ENSP00000279230/1-1234 VKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNY ENSCPOP00000019282/1-1216 VKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNY XP_004852581.1/1-1223 VKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNY ************************************************************ ENSMUSP00000025912/1-1234 MPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVI ENSRNOP00000028720/1-1236 MPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVI ENSP00000279230/1-1234 MPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVI ENSCPOP00000019282/1-1216 MPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVI XP_004852581.1/1-1223 MPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGHSGYLLKPEFMRRPDKSFDPFTEVI *********************:.************:************************ ENSMUSP00000025912/1-1234 VDGIVANALRVKVISGQFLSDKKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEE ENSRNOP00000028720/1-1236 VDGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEE ENSP00000279230/1-1234 VDGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEE ENSCPOP00000019282/1-1216 VDGIVANALSVKVISGQFLSDRKVGIYVEVDMFGLPIDTRRKYRTRTSQGNSFNPVWDEE XP_004852581.1/1-1223 VDGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPIDTRRKYRTRTSQGNSFNPVWDEE ********* ***********:**************:*********************** ENSMUSP00000025912/1-1234 PFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALL ENSRNOP00000028720/1-1236 PFDFPKVVLPTLASLRIAAFEEGGRFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALL ENSP00000279230/1-1234 PFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALL ENSCPOP00000019282/1-1216 IFEFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALL XP_004852581.1/1-1223 IFEFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALL *:*********************:*********************************** ENSMUSP00000025912/1-1234 IYTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASTETYQETPCQQ ENSRNOP00000028720/1-1236 IYTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASTEMCQETPSQQ ENSP00000279230/1-1234 IYTEASDYIPDDHQDYAEALINPIKHVSLMDQRARQLAALIGESEAQAGQETCQDTQSQQ ENSCPOP00000019282/1-1216 IYTEASDYIPGDRQDYAEALINPIKHVSLMDQRAKQLAALIGESEALGGTETCQEGPSQQ XP_004852581.1/1-1223 IYTEASDYIPGDRQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQAGTEACPEAQSQQ **********.*:*********************:*********** .. * : .** ENSMUSP00000025912/1-1234 PGSQLPSNPTPNPLDASPRWPPGPTTSSTSSSLSSPGQRDDLIASILSEVTPTPLEELRS ENSRNOP00000028720/1-1236 QGSQLSSNPAPNPLDASPRWPPGPTTSPTSTSLSSPGQRDDLIASILSEVTPTPLEELRS ENSP00000279230/1-1234 LGSQPSSNPTPSPLDASPRRPPGPTTSPASTSLSSPGQRDDLIASILSEVAPTPLDELRG ENSCPOP00000019282/1-1216 LASQPPSNPTPSPMDASPRRPPGSATSPTSTSLSSPGQRDDLIASILSEVAPIPLDELRG XP_004852581.1/1-1223 LGSQPPSNPPPSLLDTSPRRPPGLTTSPTSTSLSSPGQRDDFIASILSEVAPTALGELRG .** .***.*. :*:*** *** :**.:*:**********:********:* .* ***. ENSMUSP00000025912/1-1234 HKAMVKLRSRQDRDLRELHKKHQRKAVALTRRLLDGLAQARAEGKCRPSPSALGKATNSE ENSRNOP00000028720/1-1236 HKAMVKLRSRQDRDLRELHKKHQRKAVALTRRLLDGLAQARAEGKCRPSSSALSRATNVE ENSP00000279230/1-1234 HKALVKLRSRQERDLRELRKKHQRKAVTLTRRLLDGLAQAQAEGRCRLRPGALGGAADVE ENSCPOP00000019282/1-1216 HKALLKLRSRQERDLRELCKKHQRKAIALTRRLLQGLTQA------RPVPGVLGRAADSE XP_004852581.1/1-1223 HKALAKLRSRQERDLRELCKKHQRKAIALTRRLLESLAQA------QHAPGALGGAADLE ***: ******:****** *******::******:.*:** : ...*. *:: * ENSMUSP00000025912/1-1234 DVKE-EEE--AKQYREFQNRQVQSLLELREAQADVETKRKLEHLRQAHQRLKEVVLDTHT ENSRNOP00000028720/1-1236 DVKE-EEKEAARQYREFQNRQVQSLLELREAQADAETERRLEHLKQAQQRLREVVLDAHT ENSP00000279230/1-1234 DTKEGEDE--AKRYQEFQNRQVQSLLELREAQVDAEAQRRLEHLRQALQRLREVVLDANT ENSCPOP00000019282/1-1216 DMKE-EEE--VKQYREFQNRQVQSLLELREAQADVEAERRLEYLRQTQQRLREIVVEAHT XP_004852581.1/1-1223 DM-E-EEE--VKQYREFQNRQVQSLLELREAHADVEAERRLEHLRQTQQRLREIVLEAHT * * *:: .::*:****************:.*.*::*:**:*:*: ***:*:*::::* ENSMUSP00000025912/1-1234 TQFKRLKELNEREKKELQKILDRKRNNSISEAKTREKHKKEVELTEINRRHITESVNSIR ENSRNOP00000028720/1-1236 TQFKRLKELNEREKKELQKILDRKRNNSISEAKTREKHKKEVELTEINRRHITESVNSIR ENSP00000279230/1-1234 TQFKRLKEMNEREKKELQKILDRKRHNSISEAKMRDKHKKEAELTEINRRHITESVNSIR ENSCPOP00000019282/1-1216 AQFKRLKEMNDREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNAIR XP_004852581.1/1-1223 TQFKRLKETNEREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINRRHITESVNAIR :******* *:**************:******* *:*****.***************:** ENSMUSP00000025912/1-1234 RLEEAQKQRHERLVAGQQQVLQQLEEEEPKLLAQLTQECQEQRERLPQEIRRCLLGETAE ENSRNOP00000028720/1-1236 RLEEAQKQRHERLLAGQQQVLQQLVEEEPKLVAQLTQECQEQRERLPQEIRRCLLGETSE ENSP00000279230/1-1234 RLEEAQKQRHDRLVAGQQQVLQQLAEEEPKLLAQLAQECQEQRARLPQEIRRSLLGEMPE ENSCPOP00000019282/1-1216 RLEEAQKQRHDRLVAGQQQVLQQLAEEEPKLLAQLTQECQDQRARLPLEIRRSLLGETLE XP_004852581.1/1-1223 RLEEAQKQRHDRLVAGQQQVLQQLAEEEPKLLAQLTQECQEQRARLPQEIRRSLLGEMPE **********:**:********** ******:***:****:** *** ****.**** * ENSMUSP00000025912/1-1234 GLGDGPLVACASNGHAPGSGGHLSSADSESQEENTQL ENSRNOP00000028720/1-1236 GLGDGPLVACASNGHAAGSGGHQSGADSESQEENTQL ENSP00000279230/1-1234 GLGDGPLVACASNGHAPGSSGHLSGADSESQEENTQL ENSCPOP00000019282/1-1216 GQVDGPLVACASNGHAAGSSGHLSGTDLESQEENTQL XP_004852581.1/1-1223 GLADGSLVACASNGHAPGSSGHLSGADSESQEENTQL * **.**********.**.** *.:* *********