CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000100648/1-773 MLPTGEGAEGQDWHLDMQLPSKVVLSAAALLLVTAAYKLYKSRPAPVGQAGRNNKDHKAE ENSRNOP00000064116/1-773 MLPTRKGTEAHDWHLDMQLTSKVVLSAAALLLVTVAYKLYKSRPAPAPHAGRKKERHKAE ENSP00000383505/1-777 MFP--RGAEAQDWHLDMQLTGKVVLSAAALLLVTVAYRLYKSRPAPAQRWGGNGQA-EAK ENSCPOP00000019253/1-744 ----------------MQLMGKVVLSAVVLFLVTAAYRLYKSRPARALQKGGNIET-RSE XP_004850461.1/1-759 MLP--GGAEAQDWHLDMQLMGKVVLSAVALLLVTAAYRLYKSRPAHAPQKGGNTEA-KAE *** .******..*:***.**:******* . : * : : .:: ENSMUSP00000100648/1-773 NETEALGQLAFQEAPPGTLPRGRRRRKASKGAGTSLDYSLVDPEDPCILD---ISRSEEA ENSRNOP00000064116/1-773 NETEGLGQPAFQEAPPGTLPRGPRRRKASKGAGSPLDYSLEDPGDSYILD---TPRSEEP ENSP00000383505/1-777 EEAEGSGQPAVQEASPGVLLRGPRRRRSSKRAEAPQGCSCENPRGPYVLVTGATSTDRKP ENSCPOP00000019253/1-744 KEAEGSSQP-VQSASPGTLQRRPKRKRASHGAGAPRGCSWEDPGGPCVLDPGATCRDGKP XP_004850461.1/1-759 KEAEASGQPAVQSASPGTLQRRPRRQRSSHNAGAPLGCSWEVPGSPCVLALGATGRDRKP :*:*. .* .*.*.**.* * :*:::*: * :. . * * .. :* . :. ENSMUSP00000100648/1-773 TRKGSDESQGRQCPDSQQVPPPCGGQEAGTDVRGKPNPPHLPHSGCEPTSSSGRLIPGVG ENSRNOP00000064116/1-773 TRKGSDESQDRQRPDSQQVPPPCGGQEAGTAVRGKPNPPHPLHSGCEPTSSPARLIPGVG ENSP00000383505/1-777 QRKGSGEERGGQGSDSEQVPPCCPSQETRTAVGSNPDPPHFPRLGSEPKSSPAGLIAAAD ENSCPOP00000019253/1-744 SSK------GGQCSGSEQESLCCCGQEAGTAVGGKPTP---------PCNSSAGLAAAVD XP_004850461.1/1-759 PSK------GRQCPSSEQVPPCCCDQETGTAVDGKLTP---------PCSSLAELASSVD * . * ..*:* . * .**: * * .: * * .* . * .... ENSMUSP00000100648/1-773 GSCVGDKLSPWPDSRPPEETGSGDLEAPNG-WTDLTLVNGDMNQSWIFTHMTGVSRGEAG ENSRNOP00000064116/1-773 GSCVGDNLSPWPDSRPLEETGSGDPEAPNC-WTDPTLVNGDMNQSWIFTHMTGVSRGEAG ENSP00000383505/1-777 GSCAGGEPSPWQDSKPREHPGLGQLEPPHCHYVAPLQGSSDMNQSWVFTRVIGVSREEAG ENSCPOP00000019253/1-744 SSCGGGKRIAWPDGRPPEQPEPEELGPTEG-WVAPTEGSGDMNQNWIFSRVTEINREEPR XP_004850461.1/1-759 GSCVGGELATWMDSGSSEQPEPGKLGPPQS-WVAPMEDSSDMNQSWVFSHVTGVSREEAG .** *.: .* *. . *.. . ... :. ..****.*:*::: :.* *. ENSMUSP00000100648/1-773 VLQAAADMGLATQQQEGATNASHTFSSVARIRMEENIIQKAE--GPGLKGRVYDYFVEST ENSRNOP00000064116/1-773 ALQAAANMGLATQQQEGATSASHTFSSVARIRMEENVIQKAE--GPELKGRIYDYFVEST ENSP00000383505/1-777 ALEAASDVDLTLHQQEGAPNSSYTFSSIARVRMEEHFIQKAEGVEPRLKGKVYDYYVEST ENSCPOP00000019253/1-744 MLQAASELGLAMQQQEGATNAFYTFSSMAWVRMEENFIQKAERSGLQLKGKVYDYYVEST XP_004850461.1/1-759 TVQAASDMDLAVQQQEGATNSSYTFSSMARVRMEENFIQKAERPGPQLKGKVYDYYVEST ::**:::.*: :*****..: :****:* :****:.***** ***::***:**** ENSMUSP00000100648/1-773 SKAD--SRPVPCPAALAD-APSPGPGPEPLVTGAASRDEAANTAGGGASEAASPQPVASP ENSRNOP00000064116/1-773 SKAV--SRPVPCAAALADAAPSPGPGPEPLVTGAATRDQADNTA-GGTLQVASPQPVPSP ENSP00000383505/1-777 SQAIFQGRLAPRTAALTE-VPSPRPPPGSLGTGAASGGQAGDTK-GAAERAASPQTGPWP ENSCPOP00000019253/1-744 SRAT--SRLASRTAMLAE-PPSPGPVLEPLGTGTSSGDKAGDTE-NGDKATASPQPEMSP XP_004850461.1/1-759 SQAT--SRLAPRRAALAE-APTPGPVLETLETGASSRGQAGDAE-GGAKAIASPKPVLSP *:* .* .. * *:: *:* * .* **::: .:* :: .. ***:. * ENSMUSP00000100648/1-773 SAPGFSRKVSLLQIAENPELQLQPEGFRMPLPAHLDQRAQLSSACSHGEPHVQLVAGTNF ENSRNOP00000064116/1-773 SAPGFGRKVSLLQIAENPELQLQPEGFRMPLPAHLDQSAQLGSDCSHGEPHVQLVAGTNF ENSP00000383505/1-777 STRGFSRKESLLQIAENPELQLQPDGFRLPAPPCPDPGALPGLGRSSREPHVQPVAGTNF ENSCPOP00000019253/1-744 SAHAVSRKKSLLQIAENPELQLQPEGFREPAAAQPAQNILPGPSECSGEPHIELVARTNF XP_004850461.1/1-759 SVHGFSRKESLLEISENPELQLQPDGFGAPAPDHPDQGTLPGLSGYSGEPHVQLVARTNF *. ...** ***:*:*********:** * . . ***:: ** *** ENSMUSP00000100648/1-773 FHIPLTPASALDVRLDLGNCYEMLTLAKRQGLETLKEAAYKVLSDNYLQVLRSPDIYGGL ENSRNOP00000064116/1-773 FHIPLTPASALDVRLDLGNCYEMLTLAKRQGLEALKEAAYKVLSDNYLQVLRSTDIYGGL ENSP00000383505/1-777 FHIPLTPASAPQVRLDLGNCYEVLTLAKRQNLEALKEAAYKVMSENYLQVLRSPDIYGCL ENSCPOP00000019253/1-744 FHIPLSPASSLDICLDLGNCYEVLTWAKKQDLQALKEAVYKLMSDNYLQVLRSPDIYGCL XP_004850461.1/1-759 FHLPLSPTSALDICLDLGNCYEVLTLAKRQNLEALKEAAYKVMSDNYLQVLRSPDIYGCL **:**:*:*: :: ********:** **:*.*::****.**::*:********.**** * ENSMUSP00000100648/1-773 SGAERELILQRRFRGHKRLVVADMCPQDDSGRLCCYDNVQDAWHPLAQLPPEAMSRGCAL ENSRNOP00000064116/1-773 SGAERELILQRRFRGHKCLVVADMCPQEDSGRLCCYDNVQDAWHPLAQLPLEAMSRGCAL ENSP00000383505/1-777 SGAERELILQRRLRGRQYLVVADVCPKEDSGGLCCYDDEQDVWRPLARMPPEAVSRGCAI ENSCPOP00000019253/1-744 SGAERELILRQRLLGRKCLVVADMCPQEDCGRLCCYDDEQDAWYPLAQLPPEAVTRGCAV XP_004850461.1/1-759 SGTERELILRRRLRGRKCLVVSDMCPQENCGHLCCYDDEQDAWYPLAQLPPEAVSRGCAV **:******::*: *:: ***:*:**:::.* *****: **.* ***::* **::****: ENSMUSP00000100648/1-773 CTLFNYLFVVSGCQEPGGQPSNRVFCYNPLTAIWSEVCPLNQARPHCRLVALEGHLYAIG ENSRNOP00000064116/1-773 CSLFNYLFVVSGCQGPAGQPSNRVFCYNPLTAIWSEVCPLNQARPHCRLVALEGYLYAIG ENSP00000383505/1-777 CSLFNYLFVVSGCQGPGHQPSSRVFCYNPLTGIWSEVCPLNQARPHCRLVALDGHLYAIG ENSCPOP00000019253/1-744 CSLFNYLFVVSGCQGPGHQPSNRVFCYNPLTGIWSEVSSLNQARPHCQLVALDGYLYAIG XP_004850461.1/1-759 CSLFNYLFVVSGCQGSGYQPSNRVFCYNPLTGIWSEVSSLNQARPHCRLVALDGHLYAIG *:************ .. ***.*********.*****..********:****:*:***** ENSMUSP00000100648/1-773 GECLNTVERYDPRLDRWTFAPPLPNDTFALAHTATVCANEIFVTGGSLRYLLLRFSTQEQ ENSRNOP00000064116/1-773 GECLNTVERYDPRLDRWTFAPPLPNDTFALAHTATVCANEIFVTGGSLRYLLLRFSAQEQ ENSP00000383505/1-777 GECLNSVERYDPRLDRWDFAPPLPSDTFALAHTATVRAKEIFVTGGSLRFLLFRFSAQEQ ENSCPOP00000019253/1-744 GECLNTVERYDPRLDHWTFAPPLPSDTFALAHTATVCADEIFVTGGSLRYLLLRFSVQGQ XP_004850461.1/1-759 GECLNTVERYDPRLDRWAFAPPLPSDAFALAHTATVCAGEIFVTGGTLRYLLLRFSAQDH *****:*********:* ******.*:********* * *******:**:**:***.* : ENSMUSP00000100648/1-773 RWWAGPTGGSKDRTAEMVAVNGFLYRFDLNRSLGISVYRCSASTRLWYECATYRLPYPDA ENSRNOP00000064116/1-773 RWWAGPTAGSKDRTAEMVAVNGFLYRFDLNRSLGISVYRCNASTRLWYECATYRLPYPDA ENSP00000383505/1-777 RWWAGPTGGSKDRTAEMVAVNGFLYRFDLNRSLGIAVYRCSASTRLWYECATYRTPYPDA ENSCPOP00000019253/1-744 RWRASPTGGSKDRTAEMVAVNGFLYRFDLNRSLGISVYRCSAGTLLWYECATWRTPYPDA XP_004850461.1/1-759 RWWASPTGGSKDRTAEMVAVNGFLYRFDLNRSLGISVYRCSASTRLWYECATFRMPYPDA ** *.**.***************************:****.*.* *******:* ***** ENSMUSP00000100648/1-773 FQCAVVDDHIYCVGRRRMLCFLADHISPRFVSKELKGFPSARGTLLPAVLTLPVPDVPQT ENSRNOP00000064116/1-773 FQCAVVDDRIYCVGRRRTLCFLADHISPRFVPNELQGFPAARGTLLPAVLTLPVPDVPQT ENSP00000383505/1-777 FQCAVVDNLIYCVGRRSTLCFLADSVSPRFVPKELRSFPAPQGTLLPTVLTLPTPDLPQT ENSCPOP00000019253/1-744 FLCAVVDTRIYCVGRRRTLCFLADHISPRFVPKELQHFPSPRGTLLPTVLTLPGPHVPQT XP_004850461.1/1-759 FQCAVVDTRIYCVGRQRTLCFLADHVSPRFVPKELQHFPSPRGTLLPTVLTLPGPIVPQT * ***** ******: ****** :*****.:**: **:.:*****:***** * :*** ENSMUSP00000100648/1-773 PV ENSRNOP00000064116/1-773 PV ENSP00000383505/1-777 RV ENSCPOP00000019253/1-744 RV XP_004850461.1/1-759 RV *