CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000092286/1-1013 -MQATAALETDSDKNYPKNGGHFQNDKLYNPKKENMF-FSNGCNGVILAFPDGKEDSLAT ENSRNOP00000034920/1-1018 -MQATAVVETDSDKSYHKNGGHLQNDKLYYPKKENML-FSNGCNRVKLTFPDGEGDSLTT ENSP00000386727/1-1052 MMQATAVVETASGKGYHSNGGNLQKDKPSNPKKENLLLSSNGCDEVKLTFPDDDWNSSTL ENSCPOP00000019092/1-1038 -MQATALVETASGKGCHRDGGNVQRDLSSNAKK-----SSSGCNEVKPAYPGDEWDCLAL XP_004868449.1/1-1033 MMQATALVEMASGKGYHSSGENLQKDLSSDSKK-----SSNACNEVKLTFPDHEWDSLAL ***** :* *.*. .* :.*.* .** *..*: * ::*. . :. : ENSMUSP00000092286/1-1013 EERASDKENSIVDQRDLSELSFSENQDSNRGNIFSQSSEFEDSNDYAFLNETYSIHYSES ENSRNOP00000034920/1-1018 DERTNVKENSSVDKRDLSELSFSETQDTNVENLFSQSSEFEDNIEYAFLNETYSIHYSES ENSP00000386727/1-1052 EQRANNKEISNIDKMDLLEPFFSVSQDTNTESTQFQSSELEDSTDYAFLNKTYSIPYSES ENSCPOP00000019092/1-1038 EQRANDKEISNNSPTSSSESSFSENQDTDLQNAHSQSSEFEDRIDYASLNKTFCI-YSES XP_004868449.1/1-1033 EPRASVREISNTDTTRLLESSFSENQDTNIQSAHSQSSKFEDSIDYVFMNEIYCI-YSES : *:. :* * . * ** .**:: . ***::** :*. :*: :.* **** ENSMUSP00000092286/1-1013 KLKDENLLHLYSGLHPEVHKRVEMIFDTLD---NNSIGLGRSAEASGAD----CGDVQKS ENSRNOP00000034920/1-1018 KLKDENILHLYSELDPEVHERVEVFFDTFGPQGNNDIGLGRSCEALGSA----CGDMQKS ENSP00000386727/1-1052 KLKKESLTPLSSELDPEVQKKEEVFFNILEHQ-DKTVGLERIYNISDANYRESAEDTQKH ENSCPOP00000019092/1-1038 KLKNEDITNLNSELDPKMGKREDMFFDSLEPQGNRTIALERIHKISDANYEETAEETQRC XP_004868449.1/1-1033 ELKNENTTNLNSELDSEIEKREEAFFDILKLQGTRTVALERICEISNADYEETAGEMQKD :**.*. * * *..:: :: : :*: : . :.* * : .: . : *: ENSMUSP00000092286/1-1013 DVDEDSQQEYHSA-ELECISAHL----AKTVSRSSLDVSELKTSSYDFKCGGNFEDNHGK ENSRNOP00000034920/1-1018 DVREDSQQEYHSA-ELECLSAHLAVDPAKTVSRSSLDVSEWRTSSYTFKCGGNLEVNRGK ENSP00000386727/1-1052 DTDEDSQQEYHSAEEQEYISNHLSFDQTKALDISNPEVVELGNSGYEVKCASNVEDNRVN ENSCPOP00000019092/1-1038 DMDEDSQQEYHSAEEQEYMSNHLSFVQAEAFSISNLKVVEFRDSGYEVQCASNLED-KNT XP_004868449.1/1-1033 VIEEDSQQEYHSAEEQEYISNHLSFVQAKTSSISNLEV-ELRNSGHEVQSASNLEDNPIK ********** * * :* ** ::: . *. .* * *.: .:...*.* . ENSMUSP00000092286/1-1013 LESGPSPSLESLNGFAQECSLQVSTSQSSDMLQEYHEPKYEKCKEQEVDLTYHKAFDGIL ENSRNOP00000034920/1-1018 LESGPIPFLESLNGFSPKCSPQVSTSPSSDMLKEYHEPKYEKYKEQEVGLTYHKTFDDIL ENSP00000386727/1-1052 SGSGSIISFDSLDVYGQEESLHVSKFQNSVMLREYHDLKHEKYKEQETNSMYHTVFDGSV ENSCPOP00000019092/1-1038 LENSSVISADSLNVFAQDYTSHVSKFQNCNLLKECYAPKYEKCKEQETSLKYPTIFDDFV XP_004868449.1/1-1033 LESSSVISSDSLNVVAQEYTPCVSKFQNCDLLKEYYEPKYEKCKEQETSLMYPIVF---V ... :**: . . : **. .. :*:* : *:** ****.. * * : ENSMUSP00000092286/1-1013 QRSSSP-----------LNHQKVPETQVYTKEVKSQTTESKDFYGNRIFQNKALQRPENA ENSRNOP00000034920/1-1018 QRSSSP-----------LNSQKVPEPLVYAKEMKSQTIEGKDFYGDRIFQNRALQHPEN- ENSP00000386727/1-1052 LRSNSPGNQESQSKSGSLSPQKVLKMKIYTENMKSQINEGKDFCGNKIVENKILLHLENP ENSCPOP00000019092/1-1038 QRSTSLENKGSQSENDLLNPQKALKTKMDTNKMKCEISESKDFYENTTFKNRIPQNLENP XP_004868449.1/1-1033 QRGNSLGNEESQAKNDFLNPQTALKTKTCTETMKSQISENKDFCGNAVVKNRISQHLENP *..* *. *.. : :: :*.: *.*** : .:*: . ** ENSMUSP00000092286/1-1013 TMFPQDRALETHLKANDAHQPSGPCALDDSVISLCGSSQYKSL---PEPGF-FSPVIPRV ENSRNOP00000034920/1-1018 AMFPQDHALETPLKALDAHQLSGPYVLDDSVISLCGSLQYNSL---PEPGF-YSPVMPRV ENSP00000386727/1-1052 STLPQDKALETLLQPCKDCQTSWTSVFDDSIISACGY--YESLQNTADSALDFSAMLPKI ENSCPOP00000019092/1-1038 STFPQDETLETPQQSSHVCQTSWSSIFDDSIISACGYSRYKSLQSTPNPASSFPVVSARI XP_004868449.1/1-1033 STISQDRALETLQESSKVCQTSWSSIFDDSVISAYGCSHYESLQSTPDPALGF-AVPPRI : :.**.:*** :. . * * . :***:** * *:** .:.. : : .:: ENSMUSP00000092286/1-1013 AVTDYQAEVEGSCLHHVQGSATNKACS--LMKEVCLTSVPDAAACIAAVQQTLHVSS--- ENSRNOP00000034920/1-1018 AVTDSQAEVAGSCLHHVQGSATNKTCS--LMKEMCLKSGPDAANCVALGQQTLDVSG--- ENSP00000386727/1-1052 AVRDNQAIEDNTSLKVAHSSTTKKTCF-HNIGEMCTKSLTDAASCTVTINQTVDVSTDFR ENSCPOP00000019092/1-1038 AVRDDQGVKGDGSLKDTDGRNMNKAYS-EGGKRTHPGSVTGATDCAVTVHETVDVSTDFR XP_004868449.1/1-1033 AIRDDQTIKEDSSLKAINGNNMNKACSEEDGKGTYPKSVIDAAGCTVTVHQTVDVSTDFR *: * * . .*: .. :*: * .*: * . ::*:.** ENSMUSP00000092286/1-1013 -------RVNASSSIVSASSITETKMVRQSQAEEWQSDKR-SVACNTAWSCGQQCRDAQR ENSRNOP00000034920/1-1018 -------RANVSSSVVSTASTTETKTVRRSQPEEWQRDRQ-SVACNTDWSCGQQCRSARA ENSP00000386727/1-1052 ACFTTSRATSARPSVVSTSSNTEITMMNKKRPDEWQNEKQKSVACSTDWSYSEDCIDTQ- ENSCPOP00000019092/1-1038 ACFTTSRATNARPSVVSTASNTEVTMMSKKRPSRWQSEKQ-SVACNTDWSCCQDCVDTP- XP_004868449.1/1-1033 ACFTTSRATNARPSVVSTSSNTEVTMMSKKRPSKWQSGKQKSVACNTDWSYGQDGVDTP- ... .*:**::* ** . : :.:...** :: ****.* ** :: .: ENSMUSP00000092286/1-1013 AAPGSDSGRPLSTGCLKPSGNSLNENSLELRKVFDTTDRQKHCNRAFQLCEE--KAVPSR ENSRNOP00000034920/1-1018 AALGSDSGRPLSTDCLNC-GNSMDENSLELRKT---PDKQRHPERAFQLCEE--MALPSK ENSP00000386727/1-1052 MAITKGSGKSLSVDSLKPNGNFLNKDFLELRKACGITDLKKHPEREFQLFKDTEKDLPSM ENSCPOP00000019092/1-1038 VASTKRSGKSLLADSLKPNGNFQNKDSLEL-KTCNNTALKKHPEREFQLAEDMTKDLPSK XP_004868449.1/1-1033 VAITKGSGKSLSVDSSQPNGNFQNKDSLEL-KTYDNTDLKKHPDREFQLSEEVEKSSPSQ * . **:.* ... : ** ::: *** *. . ::* :* *** :: ** ENSMUSP00000092286/1-1013 CCQKTTERAIKAEMHLLDVCYQMCHRHCHHIYKLVMESRAGLNRNLQTDSAKKELGAALL ENSRNOP00000034920/1-1018 CCEKTTERAVKAETHLLDVCYQMCHHHCHHIYKLVMGSRAGLSRNLPTDSAQKELGTALL ENSP00000386727/1-1052 CCQKIMQRAIKAELHLLNVHYQMCRRHCCDIYKLVMENREGLNMNLSSNSAKKELGSALL ENSCPOP00000019092/1-1038 CCKKIMQRAIEAEMHLLNVRYQMCHRLCCDIYKLVIENR-GLNRNLPGNSAKKELGSALL XP_004868449.1/1-1033 CCKKVMQRLMEAEMHLLNARYEMCRRHCWDIYKLTVENK-GLNRNLLSSSAQKELGSALL **:* :* ::** ***:. *:**:: * .****.: .: **. ** .**:****:*** ENSMUSP00000092286/1-1013 SVLEDLKLRYMNLKGKVHKGIPLEELPPLSVESKLLSAFSDFVSRLMKDEACSLSGANSE ENSRNOP00000034920/1-1018 SVLEDLKARYMNLKGKVHKGIPLEELPPLSVESKLLSAFSDFASRLMKEEACSLSGANSE ENSP00000386727/1-1052 SLLGDLKVRYVTLKEKIHKGIPLEELPPLSLESKLLSTFSTFASRLMKKETHVFSEADAE ENSCPOP00000019092/1-1038 SVLGDLKVRYVNLKEKALKGIPLEELPPLSVESKLLNTFSTFLSRLDRNTLNNFSGADSE XP_004868449.1/1-1033 SISGDLKVRYTNLKEKIHKGIPLEELPLLSVESKLLITFSTFVSRLMKEESHDFSGADSE *: *** ** .** * ********* **:***** :** * *** :. :* *::* ENSMUSP00000092286/1-1013 LDNQSLPDVDVSPGLLKTLSQMSFIPDSSQPEQGKSPMSDVCKNGDTDIGFNCLKLNDKE ENSRNOP00000034920/1-1018 LDNQSLPEVAISPSLLKTLSQMSSISDSSHPKQDKLPMNNIFKNCDINIDFNHLKLNDKE ENSP00000386727/1-1052 QDNQRAHDVDVSSNLKKTLSQMSLSSDNSHATQNISPKKDDFKNGDINADFSQLKLGDKD ENSCPOP00000019092/1-1038 LGNQTASDGEVSPNLKKPHSQVSLLADNSHPKQDTSPKEDAFKNGDINVDFSQLTLDDKE XP_004868449.1/1-1033 LNDQTASASEVSPSLKETHSQMSSLPDST------SPKKDGLKNGEINVDFSQLKLDDKE .:* :*..* :. **:* .*.: * .: ** : : .*. *.*.**: ENSMUSP00000092286/1-1013 CKTVQEASEDWFDATERLIGADFSETQDSTAECEEWQPRNPL--ELKNSELHGKGQGFLI ENSRNOP00000034920/1-1018 SKNVHEASEDWFDATERLTGTDFSVTQENITESEDWDPKNPLESELKTIERLRRGKGFLI ENSP00000386727/1-1052 CRHYQETSEDWSDAKESLTGVDVSGTQGNQVEQDTWNLD--LTGEMKNVEPSQRDKGYLI ENSCPOP00000019092/1-1038 CRNNHEISEDWFDAKENVTGVDSSGTQEHLIDHDERNPKC-IAAEMKNIEPLVREKGFLI XP_004868449.1/1-1033 CRSGHEVSEHWFDAKENMTGVDSSEIQETEIDHDRQNPK--LTVEMKNVEPLQRDKGFLI .: :* **.* **.* : *.* * * : : : : *:*. * : :*:** ENSMUSP00000092286/1-1013 HVGGLCPSVSEADLRSHFQKYQVSEISIYD-STNYRYASLAFAKNSNAKMAVKEMNGVKI ENSRNOP00000034920/1-1018 HVGGLCPSVSEADLRSHFQKYQVSEISIYDSNTNYRYASLACAKNSNAKMAVKEMNGVEI ENSP00000386727/1-1052 HVGGLCPSVSEADLRSHFQKYQVSEISIYD-STNYRYASLAFTKNSDAKIAVKEMNGIEI ENSCPOP00000019092/1-1038 HVGGLCPSVSEADLRSYFQKYQVSEISIYDSSTNYRYASLAFKKNHDANMAVEEMNGTEI XP_004868449.1/1-1033 HVGGLCPSVSEADLRSYFQKYQVSEISICDSSTDYRYASLSFKKNSDAKMAVEEMNGMEI ****************:*********** * .*:******: ** :*::**:**** :* ENSMUSP00000092286/1-1013 NGKSVTVRLVKIPGEYTPPPLSTTGNSTSMNHLEKNTNKDATSASSICRLPRAKSRQLES ENSRNOP00000034920/1-1018 NGKSVNVRLVKIPGEYIPPLLSTAGNNISMNHLERNSSKDATSAASTCRLPIARSGQLES ENSP00000386727/1-1052 NGKSVNVWPVKILGEYTSPLSSKNGNRISSNNLEKSTNKQIHSEFSISRLPRTRPRQLGS ENSCPOP00000019092/1-1038 NGKSVNVRLVKTHGECRSPLFS--------NNLEISSNKEIKPGSSVSTLPRARPRQLVS XP_004868449.1/1-1033 SGKSVNVWLIETHGECTSPLSSKK----HLNNLEKNINKEINPASSVSRLARTRPRQMVS .****.* :: ** .* * *:** . .*: . * . *. ::. *: * ENSMUSP00000092286/1-1013 EQDSEFPPLDQGVKKNCNQMKSGQLLPETPFQFIPPNTLNLRSFTKIMKRLAELHPDISR ENSRNOP00000034920/1-1018 EQDSEFLPLVQGVRENCNQVKSGQSLPETPFQFIPPHTLNLRSFTKIMKRLAELHPEISR ENSP00000386727/1-1052 EQDSEVFPSDQGVKKNCKQIESAKLLPDTPVQFIPPNTLNLRSFTKIIKRLAELHPEVSR ENSCPOP00000019092/1-1038 EQDTELSPLDQDAKKNCKQVESAQLLQKMPIQFIPPNTLNLRSFTKIIKRLTELHPEVSR XP_004868449.1/1-1033 EQDSELSPLDQDAKKNCKQIESAQ-LPKIPIQFLPPNTLNFRSFTKIIKILAELHPEVSR ***:*. * *..::**:*::*.: * . *.**:**:***:******:* *:****::** ENSMUSP00000092286/1-1013 DHIIEALQEVRINHKGFLNGLSINTIVKMASSFLRNSALK ENSRNOP00000034920/1-1018 DHIIEALQEVRINHKGFLNGLSINTIVKMTSSFLRNAASR ENSP00000386727/1-1052 DHIINALQEVRIRHKGFLNGLSITTIVEMTSSLLKNSASS ENSCPOP00000019092/1-1038 DHIIDALQEVRLNHKGFLNGLSISTIVEMTSSLLKSSASQ XP_004868449.1/1-1033 HHIISALQEVRKNQKGFLKGLSISTIVEMTSSVLKKTASH .***.****** .:****:****.***:*:**.*:.:*