CLUSTAL W(1.81) multiple sequence alignment ENSP00000464391/1-1077 MPRRKQQAPRRSAAYVPEEELKAAEIDEEHVEDDGLSLDIQESEYMCNEETEIKEAQSYQ ENSMUSP00000089388/1-1084 MPRRKQQAPRRSAAYVPEEELKAAEIDEEHAEDGGLSLDIQESEFACNEETEIKEAQSYQ ENSRNOP00000055055/1-1070 -------------AYVPEEELKAAEIDEEHVEDGGLSLDIQESEFVCNEETEIKEAQSYQ ENSCPOP00000019077/1-1034 ---------------------------------------------VCDEEPEIKEAQSYQ XP_004861998.1/1-1080 MPRRKQQAPRRSAAYVPEEELKAAEIDEEHVEDGGLSLDVQESEFVCDEETEIKEAQSYQ *:**.********* ENSP00000464391/1-1077 NSPVSSATNQDAGYGSPFSESSDQLAHFKGSSSREEKEDPQCPDSVSYPQDSLAQIKAVY ENSMUSP00000089388/1-1084 NSPVSTATNQDAGYGSPFSEGSDQLAHFKSSSSREEKEESQCPDSVSYPQDSLAQIKAVY ENSRNOP00000055055/1-1070 NSPVSTATNQDAGYGSPFSEGSDQLAHFKSSTSREEKEEPQCPDSVSYPQDSLAQIKAVY ENSCPOP00000019077/1-1034 NSPISTATNQEAGYGSPFSEHSDQLAHFKSSSSREEKEEPQCPDGISYPQDSLAQIKAVY XP_004861998.1/1-1080 NSPVSTATNQDAGYGSPFSENSDQLAHFKSSSSRDEKEEPQCPDSISYPQDSLAQIKAVY ***:*:****:********* ********.*:**:***:.****.:************** ENSP00000464391/1-1077 ANLFSESCWSSLALDLKKSGSTTSTNDASQKESSAPTPTPPTCPVSTTGPTTSTPSTSCS ENSMUSP00000089388/1-1084 ANLFSESCWSSLALDLKKSNSATSNNDASQKESSTPTPTPPTSTASTACTTATTAITSCS ENSRNOP00000055055/1-1070 ANLFSESCWSSLALDLKKSSSTTSNNDASQKESSTPTPTPPTSTASTACTTATTAITSCS ENSCPOP00000019077/1-1034 ANLFSESCWSSLALDLKKSSSTTSNSDVGQKESSVPTPTP-TAVTSTASTTASTASTSCS XP_004861998.1/1-1080 ANLFSESCWSSLALDLKKSSSTTSNNDAGQKECSTPTPTPSTTTAGTTSTTASTASTSCS *******************.*:**..*..***.*.***** * ..*: .*::*. **** ENSP00000464391/1-1077 SSTSHSSTTSTSSSSGYDWHQAALAKTLQQTSSYGLLPEPSLFSTVQLYRQNNKLYGSVF ENSMUSP00000089388/1-1084 TSTSHSSTTSNSSSSGYDWHQAALAKTLQQTSSYGLLPEPSLFSTVQLYRQNNKLYGSVF ENSRNOP00000055055/1-1070 TSTSHSSTTSNNSSSGYDWHQAALAKTLQQTSSYGLLPEPSLFSTVQLYRQNNKLYGSVF ENSCPOP00000019077/1-1034 TSTSHSSTTSNSSSSGYDWHQAALAKTLQQTSSYGLLPEPSLFSTVQLYRQNNKLYGSVF XP_004861998.1/1-1080 TSTNHSSTTSNSSSSGYDWHQAALAKTLQQTSSYGLLPEPSLFSTVQLYRQNNKLYGSVF :**.******..************************************************ ENSP00000464391/1-1077 TGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNRDKDSEKTKRWSKPRKRSLMEMEGK ENSMUSP00000089388/1-1084 TGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNRDKDSEKTKRWSKPRKRSLMEMEGK ENSRNOP00000055055/1-1070 TGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNRDKDSEKTKRWSKPRKRSLMEMEGK ENSCPOP00000019077/1-1034 TGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNRDKDSEKTKRWSKPRKRSLMEMEGK XP_004861998.1/1-1080 TGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNRDKDSEKTKRWSKPRKRSLMEMEGK ************************************************************ ENSP00000464391/1-1077 EDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAITKLVPSTKKRALQDLA ENSMUSP00000089388/1-1084 EDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAITKLVPSTKKRALQDLA ENSRNOP00000055055/1-1070 EDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAITKLVPSTKKRALQDLA ENSCPOP00000019077/1-1034 EDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAITKLVPSTKKRALQDLA XP_004861998.1/1-1080 EDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAITKLVPSTKKRALQDLA ************************************************************ ENSP00000464391/1-1077 PPCSPEPAGMAAEVALSESAKDQKAANPYVTPNNRYGYQNGASYTWQFEARKAQILKCME ENSMUSP00000089388/1-1084 SPCSPEPTGVATEVALSESAKDQKTANPYVTPNNRYGYQNGASYTWQFEARKAQILKCME ENSRNOP00000055055/1-1070 SPCSPEPTGMATDVALSESAKDQKTANPYVTPNNRYGYQNGASYTWQFEARKAQILKCME ENSCPOP00000019077/1-1034 SPCSPEPAGMASEVMLSESAKDQKTANPYVTPNNRYGYQNGASYTWQFEARKAQILKCME XP_004861998.1/1-1080 SPCSPEPAGMATEVALSESAKDQKTANPYVTPNNRYGYQNGASYTWQFEARKAQILKCME .******:*:*::* *********:*********************************** ENSP00000464391/1-1077 CGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVVEEKIQSIPLPPTTHTRLPA ENSMUSP00000089388/1-1084 CGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVVEEKIQSIPLPPTTHTRLPA ENSRNOP00000055055/1-1070 CGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVVEEKIQSIPLPPTTHTRLPA ENSCPOP00000019077/1-1034 CGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVVEEKIQSIPLPPTTHTRLPA XP_004861998.1/1-1080 CGSSHDTLQQLTAHMMVTGHFLKVTTSASKKGKQLVLDPVVEEKIQSIPLPPTTHTRLPA ************************************************************ ENSP00000464391/1-1077 SSIKKQPDSPAGSTTSEEKKEPEKEK-----PP--VAGDAE-KIKEESEDSLEKFEPSTL ENSMUSP00000089388/1-1084 SSIKKQPDSPAGSVASEEKKEPEKEKEKEKAPP--AAGDAERKIKEETEDATEKFEPTAL ENSRNOP00000055055/1-1070 SSIKKQPDSPAGSVASEEKKEPEKEKEKEKAPP--TAGDTERKIKEETEDATEKFEPTAL ENSCPOP00000019077/1-1034 SSIKKQPDSPAGSTASEEKKEPEKEK-----APAVVVGDVDKKIKEESDDAAEKFEPTTL XP_004861998.1/1-1080 SSIKKQPDSPAGSMASEEKKEPEKEK-----APVVVVGDVDKKIKEESDDTAEKFEPTAL ************* :*********** .* ..**.: *****::*: *****::* ENSP00000464391/1-1077 YPYLREEDLDDSPKGGLDILKSLENTVSTAISKAQNGAPSWGGYPSIHAAYQLPGTVKPL ENSMUSP00000089388/1-1084 YQYLREEDLDDSPKGGVDILKSLENTVSTAISKAQNGAPSWGGYPSIHAAYQLPGTVKPL ENSRNOP00000055055/1-1070 YQYLREEDLDDSPKGGVDILKSLENTVSTAISKAQNGAPSWGGYPSIHAAYQLPGTVKPL ENSCPOP00000019077/1-1034 YQYLREEDLDDSPKGGVDILKSLENTVSTAISKAQNGAPSWGGYPSIHAAYQLPGTVKPL XP_004861998.1/1-1080 YQYLREEDLDDSPKGGMDILKSLENTVSTAISKAQNGAPSWGGYPSIHAAYQLPGTVKPL * **************:******************************************* ENSP00000464391/1-1077 PAAVQSVQVQPSYAGGVKSLSSAEHNALLHSPGSLTPPPHKSNVSAMEELVEKVTGKVNI ENSMUSP00000089388/1-1084 QSAVQSVQIQPSYASSVKSLSSTEHNALLHSPGSLTPPPHKSNVSAMEELVEKVTGKVSI ENSRNOP00000055055/1-1070 QSAVQSVQIQPSYASSVKSLSSTEHNALLHSPGSLTPPPHKSNVSAMEELVEKVTGKVSV ENSCPOP00000019077/1-1034 QAAVQSVQVQPSYASSVKSLSATEHNALLHSPGSLTPPLHKSNVSAMEELVEKVTGKVSI XP_004861998.1/1-1080 QAAVQSVQVQPSYASSMKSLSTTEHNALLHSPGSLTPPPHKSNVSAMEELVEKVTGKVIV :******:*****..:****::*************** ******************* : ENSP00000464391/1-1077 KKEERPPEKEKSSLAKAASPIAKENKDFPKTEEVSGKPQKKGPEAETGKAKKEGPLDVHT ENSMUSP00000089388/1-1084 KKEERPTEKEKSSPVKAISPVAKENKDLPKTEETGSKPQKKGSDSETGKAKKESTLDAHT ENSRNOP00000055055/1-1070 KKEERPTEKEKASPVKAISPVAKENKDLPKSEETGSKPQKKGSDLETGKAKKESTVDAHT ENSCPOP00000019077/1-1034 KKEEKPAEREKSSPVKAVSPVAKENKDFPKSEEVGSKQQKKGPEADTGRAKKEGPVDAHT XP_004861998.1/1-1080 KKEERSAEKEKSSPTKAASPVAKENKDFPKSEEIGGKQQKKGPEAETGKAKKESPVDAHT ****:..*:**:* .** **:******:**:** ..* ****.: :**:****..:*.** ENSP00000464391/1-1077 PNGTEPLKAKVTNGCNNLGIIMDHSPEPSFINPLSALQSIMNTHLGKVSKPVSPSLDPLA ENSMUSP00000089388/1-1084 PNGTEPLKAKVTNGCGHLGIITDHSPEPSFINPLSALQSIMNTHLGKVSKPVSPSLDPLA ENSRNOP00000055055/1-1070 PNGTEPLKAKVTNGCSNLGIITDHSPEPSFINPLSALQSIMNTHLGKVSKPVSPSLDPLA ENSCPOP00000019077/1-1034 PNGTEPLKAKVTNGCNNLGIITDHSPEPSFINPLSALQSIMNTHLGKVSKPVSPSLDPLA XP_004861998.1/1-1080 PNGTEALKARVTNGCNNLGIITDHSPEPSFISPLSALQSIMNTHLGKVSKPVSPSMDPLA *****.***:*****.:**** *********.***********************:**** ENSP00000464391/1-1077 MLYKISNSMLDKPVYPATPVKQADAIDRYYYENSDQPIDLTKSKNKPLVSSVADSVASPL ENSMUSP00000089388/1-1084 MLYKISNSMLDKPVYPTTPAKQADAIDRYYYENSDQPIDLTKSKNKPLVSGVADAVSSPL ENSRNOP00000055055/1-1070 MLYKISNSMLDKPVYPTTPAKQADAIDRYYYENSDQPIDLTKSKNKPLVSGVADAVSSPL ENSCPOP00000019077/1-1034 MLYKISNSMLDKPLHSSTPRKQADAIDRYYYENSDQPIDLTKSKSKPLVSGMADSVSSPL XP_004861998.1/1-1080 MLYKISNSMLDKPVYPTTPVKQADAIDRYYYENSDQPIDLTKSKNKPLVSGVADSVSSPL *************::.:** ************************.*****.:**:*:*** ENSP00000464391/1-1077 RESALMDISDMVKNLTGRLTPKSSTPSTVSEKSDADGSSFEEALDELSPVHKRKGRQSNW ENSMUSP00000089388/1-1084 RESALMDISDMVKNLTGRLTPKSSTPSTVSEKSDADGSSFEEALDELSPVHKRKGRQSNW ENSRNOP00000055055/1-1070 RESALMDISDMVKNLTGRLTPKSSTPSTVSEKSDADGSSFEEALDELSPVHKRKGRQSNW ENSCPOP00000019077/1-1034 RESALMDISDMVKNLTGRLTPKSSTPSTVSEKSDADGSSFEEALDELSPVHKRKGRQSNW XP_004861998.1/1-1080 RESALMDISDMVKNLTGRLTPKSSTPSTVSEKSDADGSSFEEALDELSPVHKRKGRQSNW ************************************************************ ENSP00000464391/1-1077 NPQHLLILQAQFASSLRETTEGKYIMSDLGPQERVHISKFTGLSMTTISHWLANVKYQLR ENSMUSP00000089388/1-1084 NPQHLLILQAQFASSLRETAEGKYIMSDLGPQERVHISKFTGLSMTTISHWLANVKYQLR ENSRNOP00000055055/1-1070 NPQHLLILQAQFASSLRETAEGKYIMSDLGPQERVHISKFTGLSMTTISHWLANVKYQLR ENSCPOP00000019077/1-1034 NPQHLLILQAQFASSLRETAEGKYIMSDLGPQERVHISKFTGLSMTTISHWLANVKYQLR XP_004861998.1/1-1080 NPQHLLILQAQFASSLRETAEGKYIMSDLGPQERVHISKFTGLSMTTISHWLANVKYQLR *******************:**************************************** ENSP00000464391/1-1077 RTGGTKFLKNLDTGHPVFFCNDCASQFRTASTYISHLETHLGFSLKDLSKLPLNQIQEQQ ENSMUSP00000089388/1-1084 RTGGTKFLKNLDTGHPVFFCNDCASQFRTASTYVSHLETHLGFSLKDLSKLPLSQIQEQQ ENSRNOP00000055055/1-1070 RTGGTKFLKNLDTGHPVFFCNDCASQFRTASTYISHLETHLGFSLKDLSKLPLSQIQEQQ ENSCPOP00000019077/1-1034 RTGGTKFLKNLDTGHPVFFCNDCASQFRTASTYISHLETHLGFSLKDLSKLPLSQIQEQQ XP_004861998.1/1-1080 RTGGTKFLKNLDTGHPVFFCNDCASQFRTASTYITHLETHLGFSLKDLSKLPLSQIQEQQ *********************************::******************.****** ENSP00000464391/1-1077 N-VSKVLTNKTLGPLGATEEDLGSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLIYV ENSMUSP00000089388/1-1084 SVVSKALTNKTLGPLGSSEEDLGSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLIYV ENSRNOP00000055055/1-1070 S-VSKALANKTLGPLGSSEEDLGSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLIYV ENSCPOP00000019077/1-1034 S-VSKVLVSKTLGPLGAAEEDVGSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLIYV XP_004861998.1/1-1080 N-VSKVLVNKTLGPLGAAEEDLGSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLIYV . ***.*..*******::***:************************************** ENSP00000464391/1-1077 TELEKQ ENSMUSP00000089388/1-1084 TELEKQ ENSRNOP00000055055/1-1070 TELEKQ ENSCPOP00000019077/1-1034 TELEKQ XP_004861998.1/1-1080 TELEKQ ******