CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000093497/1-911 MSLGSLPLESVEVESFHTRFSAWTPFKNQSLNRQLFQERVTLISHWFDLWTNKQRREFLF ENSRNOP00000058467/1-811 ------------------------------------------------------------ ENSP00000387388/1-904 ------------MESFHTRFSAWTPFSNKSLNRQLFQERVALISHWFDLWTNKQRQEFLF ENSCPOP00000018894/1-826 ------------------------------------------------------------ XP_004846121.1/1-917 MSGGNSSQETLEMDSFHTRFSTWTPFSNKSLNRQLFQERVALVSHWFELWTNKQRQQFLF ENSMUSP00000093497/1-911 VILSQCSKSQLRFIQDWFSERKQVARVDFSTVLPRFISLYIFSFLNPKDLCAAAQVSWPW ENSRNOP00000058467/1-811 -----------RFIQDWLSERKQVARVDFSTVLPRCISLYIFSFLNPKDLCAAAQVSWPW ENSP00000387388/1-904 AIFLRCTKSQLRFVQDWFSERMQVAKVDFSTVLPRFISLYIFSFLSPKDLCAAAQVSWPW ENSCPOP00000018894/1-826 ---------------------KPMARVDFSTVLPRRISLYIFSFLNPKDLCAAAQVSWPW XP_004846121.1/1-917 TIFLQCSKSQLRFVQDWFSERKQVARVDFCTVLPRFISLYIFSFLNPKDLCAAAQVSWPW :*:***.***** *********.************** ENSMUSP00000093497/1-911 KFLTEQDCLWMPKCTKFGWFLPYTPTQNEYGAWKHHYIACVSSLDWLTPREAAAVYGTLN ENSRNOP00000058467/1-811 KFLTEQDCLWMPKCTRFGWFLPYAPTRNEYGAWKQHYIACVSSLDWLTPREAAAVYGTLN ENSP00000387388/1-904 KFLTEQDCLWMPKCVKFGWFLPYTPTDNEYGAWKRHYIACVSHLDWLTPREAAATYGTLN ENSCPOP00000018894/1-826 RFLTEQDCLWMPKCVRFGWFLPYTPADKEYGAWKHHYLACVADLDWLTPREAAAVHGTLR XP_004846121.1/1-917 KFLTEQDCLWMPKCVKFGWFLPYTPADNEYGAWKHHYIACVTHLDWLTPREAAAVYGTLN :*************.:*******:*: :******:**:***: ***********.:***. ENSMUSP00000093497/1-911 EPKTEDEEFQERRREKCLRKIIWENIAFRKKELFKARPPWLSGTRCSRLLKSTSLPGGPQ ENSRNOP00000058467/1-811 EPKTEDEELQERQREKCLRKTIWEKIALRKKELFKARPPWLTGTRCSRSLKCTSLPGGPQ ENSP00000387388/1-904 EPKTEDEELLERQREKCLRKRIWEKIALRKKELFKVRPPWVSGTCCSSVLKPRCQPRLSQ ENSCPOP00000018894/1-826 EPNTEAEELPERQREKCLRKIIWEKTALRKKESLRVRPPWGSAAGCSRWCTPRGPPPVSQ XP_004846121.1/1-917 EPKTEDEEVQERQRERCLRKIIWEKTALRKKELLRARPPWGSGDCCSRSFTSKCQLRLSR **:** **. **:**:**** ***: *:**** ::.**** :. ** . .: ENSMUSP00000093497/1-911 LWRDGTGFYEALERQFLRASLDALPKRSNISGSHSYPLLLKKHHHGVGRTD-----ALPL ENSRNOP00000058467/1-811 LWRDRTGFCEALERQFLRASLDALPQRSNISGSHSYLSLLKKSHPELGRTDDSSSCESPL ENSP00000387388/1-904 TVRERVGLHEALEKQLVLTSLETLPKRSNISGSHSYPLLSKKNWHGVHKNDDRSSYALRP ENSCPOP00000018894/1-826 RWRDSAGSQGASEKELVLASLEVLPTRSNVSGSHSYPSLSKKNWHGVANKDE-------P XP_004846121.1/1-917 MLRDLSGLQGASEKELVLASLDVLPTRSNVSGSHSYSLLSKKNWCGVHKKDDSSSYALQP *: * * *:::: :**:.** ***:****** * ** : ..* ENSMUSP00000093497/1-911 HAILISSRIPAYEMVMESIKPDVVAVLYEHSGVTLEGLLQLTDRALQGRKAQSLGIFSSG ENSRNOP00000058467/1-811 HVILISSRIPAYEMVLDSVKAGVVAVLYEPRGVTFEGLLHLLGRALQGRKAQGLGIFSSG ENSP00000387388/1-904 HFMLISSRIPAYEMVMESVKAGVVSVVYEHS-VTLESLLYLIEKALDGQKAQSIGIFSDG ENSCPOP00000018894/1-826 RFILISSRIPAYELLVDSVQAGVLSAVYEYS-KPLDSLLCLTEKALAGRKARSVGIFSDG XP_004846121.1/1-917 HFILISSRVPAYELVAESVQAGVLSAVYEHSGGTLDGLLQLIETALRGRKARSVGIFSDG : :*****:****:: :*::..*::.:** .::.** * ** *:**:.:****.* ENSMUSP00000093497/1-911 NSREIDLLQGYKICIKNVLWPEVRDFWEKLGSRVATEEEGGHVDLFVPLGASEAGIEVLS ENSRNOP00000058467/1-811 NSREIDLLQGYKICIKNLLWPEVRDFWEKLGSCVTTEEEGGHVDLFVPLGASETGIEVLS ENSP00000387388/1-904 DSREINLLQGYKIGVKNLLRPEVRDFWEKLGSYVATEEEGGHVDFFVPLGASEAGIEVLS ENSCPOP00000018894/1-826 DSREMNLLQGYKIDIENLLKPEVRDFWETLGSFVATEEEGGHVDLFVPLGASEAGVEALS XP_004846121.1/1-917 DSREINLLQGYKIGIENLLRPEVRDFWEKLGSYVATEEEGGHVDLFVPLGASEAGVEVLS :***::******* ::*:* ********.*** *:*********:********:*:*.** ENSMUSP00000093497/1-911 QLSQLTGTWFSAPTGIATGSYQHILSDWLGPHQDRTPLSNYFSESKLQAWSSFTEFLEDT ENSRNOP00000058467/1-811 LLSQLTGTSFSAPAGVATGSYQHKLARRL--------RGVLFALTRLTQ----------- ENSP00000387388/1-904 QLSQLTGTFFTAPTGIATGSYQHILSDWLGSQWGKAPSSIYFCESKLQTWSSFTDFLEET ENSCPOP00000018894/1-826 QLSQLTGTLFTAPTGVATGSFQHILSEWLGPPGDGAPPSTYFSPAKLQTWACWAELLEEA XP_004846121.1/1-917 QLSQLTGTLFTAPLGIATGSYQHVLSEWLGPPPDGAPPSVYFSESKLQTWAHAADLLEDA ******* *:** *:****:** *: * . *. ::* ENSMUSP00000093497/1-911 LKSVRKTLNPLFKNLQKSISGRMIGQFMFDTLGMDSILNNQGPAQALADGLMELSKEGSE ENSRNOP00000058467/1-811 ---------------SKHSVCHISGQFMFDTLGMDSILNNQGVAQALADGLMELSKEGSE ENSP00000387388/1-904 LKTVRKQLYPFFKELQKSISGRMIGQFMFDTMGMTNILNNQDTAQALADGLMELSKEDSE ENSCPOP00000018894/1-826 LKSVRKELGPLLKDLQKVISARMVGQIMSDSMTTASILDNQDTARALADGLVELSKEHAK XP_004846121.1/1-917 LKSVRKQLGPFLKELQKGISARMVGQFMFDSMSTEDILNNQDTAQALVDGLGELSKEHSV .* :: **:* *:: .**:**. *:**.*** ***** : ENSMUSP00000093497/1-911 GSAIEDNSQDSKSSPGQSNLNVEVLVKLERKLQMNSVETRAQVVRELVQSERRYVQMLRI ENSRNOP00000058467/1-811 RSSIEDNSQDTKSSPRQSNLNMEALTTLERRLQMDSVEKRTRVVKELVQSERRYVQTLGI ENSP00000387388/1-904 RNVVEDNSWDTKSRLSKNDLNFEALINLERILQKDSAEKRARVVRELLQSERKYVQILEI ENSCPOP00000018894/1-826 TNVIAGDCRDTKSSLSKSDL--EGLVELERTLQRHPWERRAAVARELLQSERRYVQLLAA XP_004846121.1/1-917 RNVIEDKSQDTKSSLSKSALNLEGLVKLERRLRRDWAERRSAAVRELLRSERKYVQLLET . : ... *:** :. * * * *** *: . * *: ..:**::***:*** * ENSMUSP00000093497/1-911 VQDVYAKPLRAALSSNRAILSAANIHIIFSDILHILNLNREFLDNLRDRLQEWSPAHCVG ENSRNOP00000058467/1-811 VRDVYARPLRAALSSNRAILSAANIHIIFSDTLHILNLNREFLDNLRDRLQEWSPAHCVG ENSP00000387388/1-904 VRDVYVAPLKAALSSNRAILSAANIQIIFCDILQILSLNRQFLDNLRDRLQEWGPAHCVG ENSCPOP00000018894/1-826 VRDVYATPLRAALASNRAILSAANIRIIFSDILRILSLNRQLLDNLRDRLQEWGPAHCVG XP_004846121.1/1-917 VRDVYAAPLGAALSANRAILSAANIQIIFSDILRILSLNRQFLGNLGDRLQEWGPAHCVG *:***. ** ***::**********:***.* *:**.***::*.** ******.****** ENSMUSP00000093497/1-911 EIFIKFGSQLNIYTNFFNNYPVVLKTIEKCREMTPAFRAFLKRHDKTIVTKMLSLPELLI ENSRNOP00000058467/1-811 EIFIKFGSQLNVYTNFFNNYPVVLKTIEKCREMAPAFRAFLKRHDRTIVTKMLSLPELLL ENSP00000387388/1-904 EIVTKFGSQLNTYTNFFNNYPVILKTIEKCREMIPAFRTFLKRHDKTIVTKMLSLPELLL ENSCPOP00000018894/1-826 EIFIKFGSQLNTYTNFFNNYPVVLRTIEKCREAAPAFRAFLQRCDKTIVTHMLSLPELLL XP_004846121.1/1-917 DIFIKFGSQLNTYTNFFNNYPVVLRTIEKCREMTPAFRAFLKRHDKTIVTHMLSLPELLL :*. ******* **********:*:******* ****:**:* *:****:********: ENSMUSP00000093497/1-911 YPSRRFEEYIHLLYALRLHTPAGHVDRGDLTTAIDQVKKYKGYIDQIKENLKMREQLSDV ENSRNOP00000058467/1-811 YPSRRFEEYIHLLYALRLHTPAGHVDRGNLTTAIEQIKKYKDYIDQIKENFKMREQLSDI ENSP00000387388/1-904 YPSRRFEEYLNLLYAVRLHTPAEHVDRGDLTTAIDQIKKYKGYIDQMKQNITMKDHLSDI ENSCPOP00000018894/1-826 CPSRRFDEYLTLLYALRLHTPAGHVDCGELTAAIDQIKRYKGYLDKIKENVSMKEQLSDV XP_004846121.1/1-917 YPFRRFEEYIHLLYALKLHTPAEHVGHGDLNTAINQIKTYKDYIDQIKENIHMKEQLSDI * ***:**: ****::***** **. *:*.:**:*:* **.*:*::*:*. *:::***: ENSMUSP00000093497/1-911 QTLICGCPTLSEANRYLIRTQDVVQLHCCDEKMDFSLRLYEQIRDLSLLLFNDVLLVSSR ENSRNOP00000058467/1-811 QTLIWGCPTLSEANRYLIRIQDVVQLQCCEEKTEFYLRLYEQTQDLSLFLFSDVLLVTSR ENSP00000387388/1-904 QRIIWGCPTLSEVNRYLIRVQDVAQLHCCDEEISFSLRLYEHIHDLSLFLFNDALLVSSR ENSCPOP00000018894/1-826 QRLVWGCPALSEVNRYLIRVQDVVQLHCADEEVSFSLRVYEQTRDLTLFLLSDALLISSR XP_004846121.1/1-917 QRLIWGCPTLSEANRYLIRVQDVVQLRCCDEEISFSLRVYEQIRDLTLFLFNDALLVSSR * :: ***:***.****** ***.**:*.:*: .* **:**: :**:*:*:.*.**::** ENSMUSP00000093497/1-911 STSHTPFEKTSKTTYQFTASVALPRLLIEDIPDSKYIKNAFILRGSKREWICATEVSDDK ENSRNOP00000058467/1-811 STSHTPFEKTCKTTYRFSASVALPRVLIEDIPDSRYIKNAFVLRGLKRDWICATESPDDK ENSP00000387388/1-904 GTSHTPFERTSKTTYQFIASVALHRLLIENIPDSKYVKNAFILQGPKYKWICATEIEDDK ENSCPOP00000018894/1-826 GTSHTPFERTSKTTYQFTASVALHRLLIKDIPDSKYVKNAFILQGPKREWICATEVEDDK XP_004846121.1/1-917 GTSHIPFERISKTTYQFTASVALHRLLIEDIPDSKYVKNAFILQGPKHEWLCATEVEDDK .*** ***: .****:* ***** *:**::****:*:****:*:* * .*:**** *** ENSMUSP00000093497/1-911 FLWLSVLQHAIRSSMK- ENSRNOP00000058467/1-811 FLWLSVLQHAIRSSMK- ENSP00000387388/1-904 FLWLSVLRNAIKSSMEK ENSCPOP00000018894/1-826 FLWLSVLKRAIRSSMEK XP_004846121.1/1-917 FLWMSILQKAIRSSVEK ***:*:*:.**:**::