CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000107793/1-1032 ------------------MENMPPQSWILTCFCLLSSGTSAIFHKANYSRSYPCDEIRHN ENSRNOP00000066040/1-1029 ---------------------MSPQSWILTCFCLLSSGTSAVFLKGNFSRSYPCDEKRHN ENSP00000312082/1-1059 MKESSLQNSSCSLGKETKKENMFLQSSMLTCIFLLISGSCELCAEENFSRSYPCDEKKQN ENSCPOP00000017959/1-1035 ---------------------MSLQSSILTCIFLLLLGSGQFSAE--YSRSFPCDESRQN XP_004871066.1/1-1035 ---------------------MPLQPSILTCIFLLISGSCEFFTE--NSRSFPCDESRQN * *. :***: ** *: . : ***:**** ::* ENSMUSP00000107793/1-1032 SLVIAECNHRQLHEVPQTIGKYVTNIDLSDNAITHITKESFQKLQNLTKIDLNHNAKQQH ENSRNOP00000066040/1-1029 ALVTAECNHRQLHEVPQTIGKYVTDVDLSDNTIMHITNESFQKFRNLTKINLNHNAKQQH ENSP00000312082/1-1059 DSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQH ENSCPOP00000017959/1-1035 SSVIAECNNRRLQEVPKTVGRNVTELDLSDNLITHITNGSFQGLHKLTRLNLNHNANQQH XP_004871066.1/1-1035 ASVIAECNSRRLQAVPKTVGRNVTELDLSDNFITHITNESFQGLQKLTRINLNHNANQQH * ***. *:*: **:*:*: **::***** * ***: *** :::**:::****.: ** ENSMUSP00000107793/1-1032 PNEN----KNGMNITEGALLSLRNLTVLLLEDNQLYTIPAGLPESLKELSLIQNNIFQVT ENSRNOP00000066040/1-1029 PNEN----KNGMNITEGAFLSLRNLTELLLEDNQLYTIPAGLPESLKELSLIQNNIFQVT ENSP00000312082/1-1059 QNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNIT ENSCPOP00000017959/1-1035 QEEYPGIVKTGMNITDGAFLSLKNLKELLLEDNQLNKIPTGLPESLTEFSLIQNNIILVT XP_004871066.1/1-1035 QDENPNINKTGMNITDGAFLNLKNLKQLLLEDNQLYKIPTGLPESLRELSLIQNNIVSVT : ..*:***:**:*.*:** ******** **:****** *:******* :* ENSMUSP00000107793/1-1032 KNNTFGLRNLERLYLGWNCYFK--CNQTFKVEDGAFKNLIHLKVLSLSFNNLFYVPPKLP ENSRNOP00000066040/1-1029 KNNTFGLRNLERLYLGWNCYFK--CNQIFKVEDGAFNNLINLKLLSLSFNNLFSVPPKLP ENSP00000312082/1-1059 KEGISRLINLKNLYLAWNCYFNKVCEKT-NIEDGVFETLTNLELLSLSFNSLSHVPPKLP ENSCPOP00000017959/1-1035 KNNTSELRNLQKFSLSWNCYFA--CNKTFEVEDGTFENLTNLKELSLSFNTLIHVPPKLP XP_004871066.1/1-1035 KNNTLELGNLEKFYLSWNCYFA--CNKTFEVKDGAFEKLTNLKELSLSFNTLNHVPPKLP *:. * **:.: *.***** *:: :::**.*:.* :*: ******.* ****** ENSMUSP00000107793/1-1032 SSLRKLFLSNAKIMNITQEDFKGLENLTLLDLSGNCPRCYNAPFPCTPCKENSSIHIHPL ENSRNOP00000066040/1-1029 SSLSKLFLSNAKISTITQEDFKGLEHLILLDLSGNCPRCFNAPFPCESCNLSASIRIHPL ENSP00000312082/1-1059 SSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRF ENSCPOP00000017959/1-1035 SSLERLYLSNAKIKAIGPEDFKGLGNLSSLDLSGNCPRCFNAPFPCTPCEGDASLKIHPL XP_004871066.1/1-1035 SSLVTLYLSNAKIQTIGPEDFKGLGNLSSLDLSGNCPRCFNAPFPCTPCEGGASLKIHPL *** *:***::* * ****** :* **********:****** .*. .:*:.*. : ENSMUSP00000107793/1-1032 AFQSLTQLLYLNLSSTSLRTIPSTWFENLSNLKELHLEFNYLVQEIASGAFLTKLPSLQI ENSRNOP00000066040/1-1029 AFQNLTQLRFLNLSSTSLRTIPSTWFDNLTNLKELHLEFNYLVQEIASGAFLTKLPSLQT ENSP00000312082/1-1059 AFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEI ENSCPOP00000017959/1-1035 AFQNLSNLHHLNLSSTSLQTVNSTWFDNMPYLKELHLEFNYLVHEIASGAFLTKLPNLKI XP_004871066.1/1-1035 AFQNLTKLLSLNLSSTSLQTVDSTWFDNMPSLKALHLEFNYLVQEIASGAFLTKLPNLET ***.*::* ********:.: ::**.*:. ** *.******* ********* ** *: ENSMUSP00000107793/1-1032 LDLSFNFQYKEYLQFINISSNFSKLRSLKKLHLRGYVFRELKKKHFEHLQSLPNLATINL ENSRNOP00000066040/1-1029 LDLSFNFIHKEYLQYITISPNFSMLRSLRKLHLKGYVFRELKKEHFKPLQNLPNLTTINL ENSP00000312082/1-1059 LDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINL ENSCPOP00000017959/1-1035 LDLSFNYVKTQYKQYIKLSPNFSKLTHLEALHLRGYVFQVLRREDFEPLMGLSHLKTINL XP_004871066.1/1-1035 LDLSFNYVKTEYFQYINLSSNFSKLEKLEALHLRGYVFQELRREDFQPLMGLPHLKTINL ******: .* *.*.:* *** * *. ***:****: *:...*: * *.:* **** ENSMUSP00000107793/1-1032 GINFIEKIDFKAFQNFSKLDVIYLSGNRIASVLDGT-----DYSSWRNRLRKPLSTDDDE ENSRNOP00000066040/1-1029 GINFIEKIDFKAFQDFPNLKVIYLSGNRIASVIDGT-----DHSSWRNRLRKPLSTDYDE ENSP00000312082/1-1059 GINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDF-E ENSCPOP00000017959/1-1035 GINFIKQIDFNIFKNFSSLKVIYLSENRISPLVDDTRQTSAKGFPLQNHNRKPRSTDS-E XP_004871066.1/1-1035 GVNFIKQIDFKIFKNLPSLKVIYLSENRISPLVDDTRQNCANGSSFQNHNRKPRSPDS-E *:***::***: *:::..*.:**** ***:.::..* . . :.: ** *.* * ENSMUSP00000107793/1-1032 FDPHVNFYHSTKPLIKPQCTAYGKALDLSLNNIFIIGKSQFEGFQDIACLNLSFNANTQV ENSRNOP00000066040/1-1029 FDPHMNFYHSTEPLIKPQCTTYGKALDLSLNNIFVIGKSQFEGFQDIACLNLSFNANGQV ENSP00000312082/1-1059 FDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQV ENSCPOP00000017959/1-1035 FDPHSNFYHPSYPLMKPQCTRYGKALDLSLNSIFFIGRRQFEDFQDIVCLNLSSNGNGQV XP_004871066.1/1-1035 FDPHSNFYHPTYPLMKPQCTSYGKALDLSLNSIFFIGRKQFEDFQDIVCLNLSSNGNGQV **** **** : **:****: **********.**.** ***.: **.***** *.* ** ENSMUSP00000107793/1-1032 FNGTEFSSMPHIKYLDLTNNRLDFDDNNAFSDLHDLEVLDLSHNAHYFSIAGVTHRLGFI ENSRNOP00000066040/1-1029 LNGTEFSSMPHIKYLDLTNNRLDFDDNQTFSDLHDLEVLDLSHNAHYFSIAGVTHRLGFI ENSP00000312082/1-1059 LSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFI ENSCPOP00000017959/1-1035 FNGSEFSTVRQVKYLDLTNNRLDFDDDNALSELHNLEVLDLSRNSHYFRIAGVTHRLGFL XP_004871066.1/1-1035 FNGSEFSTVSQVKYLDLTNNKLDFDDDNALSALHNLEVLDLSRNEHYFKIAGVTHRLGFL :.*:***:: ::********:****: .::: * :******* * *** ******:* *: ENSMUSP00000107793/1-1032 QNLINLRVLNLSHNGIYTLTEESELKSISLKELVFSGNRLDRLWNANDGKYWSIFKSLQN ENSRNOP00000066040/1-1029 QNLIKLKVLNLSHNGIYTLTDEYKLQSKSLKELVFSGNRLDRLWNANDGKYWSIFTSLET ENSP00000312082/1-1059 QNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKN ENSCPOP00000017959/1-1035 ENLTHLKVLNLSYNSIYTLTEENELKSASLEELNFSGNRLDLLWKPGDTRYWPIFKCLSN XP_004871066.1/1-1035 QNLTHLKVLNLSYNSIYTLTEEKELKSMSLEELNFSGNRLDLLWKTGDTSYWPIFKCLSN :*: :*:*****:*.*****:: :*:* ** ** ******* **: .* * .**. *.. ENSMUSP00000107793/1-1032 LIRLDLSYNNLQQIPNGAFLNLPQSLQELLISGNKLRFFNWTLLQYFPHLHLLDLSRNEL ENSRNOP00000066040/1-1029 LTRLDLSYNNLQQIPNEAFLNLPQSLQELHINDNRLRFFNWTLLQYFPHLHVLDLGRNEL ENSP00000312082/1-1059 LTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKL ENSCPOP00000017959/1-1035 LSRLDLSDNRLQRIPNEAFLNLPQNLTHLYLKDNILNFFNWTLLQHFPQLRVLDLSGNQL XP_004871066.1/1-1035 LTRLDLSDNNLQRIPNDAFLNLPQGLIHLYLKDNILNFFNWTLLQQFPRLQVLDLSGNQL * ***** *.*::*** ****** .* .* :..* *.******** **:*.:*** *:* ENSMUSP00000107793/1-1032 YFLPNCLSKFAHSLETLLLSHNHFSHLPSGFLSEARNLVHLDLSFNTIKMINKSSLQTKM ENSRNOP00000066040/1-1029 YFLTNCLSKFTHSLKTLLLNHNHFSHLPAGFLSEARNLVYLDLSFNTIKMINKSSLQTET ENSP00000312082/1-1059 LFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKT ENSCPOP00000017959/1-1035 SSLASSLSRFTSSLQTLLLSQNRISHLPSGFLSGASSLMHLDLSSNLIKMINKSTLQTKT XP_004871066.1/1-1035 SSLTSSLSRFTSSLQTLLLSQNRISHLPSGFLSGASSLMYLDLSSNLIKMINKSTLQTKT *...** *: **.****.:*::****:**** . .* :**** * :* ****:*:*: ENSMUSP00000107793/1-1032 KTNLSILELHGNYFDCTCDISDFRSWLDENLNITIPKLVNVICSNPGDQKSKSIMSLDLT ENSRNOP00000066040/1-1029 KTNLSVLDLQGNHFDCTCDISDFRSWLEENPHVRIPRLVDVICSNPGDQRWKSVMSLDLT ENSP00000312082/1-1059 TTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLELT ENSCPOP00000017959/1-1035 AADLSSLKLDGNPFDCTCDIGDFRRWMDENLNVTIPRLADVICASPGDQSGKSIVTLELT XP_004871066.1/1-1035 TTNLATLKLDGNPFDCTCDIGDFRRWMDENLSVSIPRLTDVICASPGDQSGKSIVSLELT :.*: *.*.** *:*****.*** *::*: : **:*.:***:.**** **:::*:** ENSMUSP00000107793/1-1032 TCVSDTTAAVLFFLTFLTTSMVMLAALVHHLFYWDVWFIYHMCSAKLKGYRTSSTSQTFY ENSRNOP00000066040/1-1029 TCVSDTTAAILFFFTFLTTSTVLLAALVHHLFYWDVWFIYHMCSAKLRGYRSSSTSQTFY ENSP00000312082/1-1059 TCVSDVTAVILFFFTFFITTMVMLAALAHHLFYWDVWFIYNVCLAKVKGYRSLSTSQTFY ENSCPOP00000017959/1-1035 TCVSDGIAAALFLCTFFLTTSVMLVALAHHLFYWDVWFMYQMCSAKVRGYRSLSTSQTFY XP_004871066.1/1-1035 TCVSDSTAAALFFLTFFITILVMLVALAHHLFYWDVWFMYQMCLAKVKGYRSLSTSQTFY ***** *. **: **: * *:*.**.**********:*::* **::***: ******* ENSMUSP00000107793/1-1032 DAYISYDTKDASVTDWVINELRYHLEESEDKSVLLCLEERDWDPGLPIIDNLMQSINQSK ENSRNOP00000066040/1-1029 DAYISYDTKDASVTDWVINELRYHLEESEDKSVLLCLEERDWDPGLPIIDNLMQSINQSK ENSP00000312082/1-1059 DAYISYDTKDASVTDWVINELRYHLEESRDKNVLLCLEERDWDPGLAIIDNLMQSINQSK ENSCPOP00000017959/1-1035 DAYISYDTRDASVTDWVINELRYHLEESEDKNVLLCLEERDWDPGLAIIDNLMQSINQSK XP_004871066.1/1-1035 DAYISYDTRDASVTDWVINELRYHLEDSKGKNALLCLEERDWDPGLAIIDNLMQSINQSK ********:*****************:*..*..*************.************* ENSMUSP00000107793/1-1032 KTIFVLTKKYAKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQYSQYLRLRQRICKSS ENSRNOP00000066040/1-1029 KTIFVLTKKYAKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQYSQYLRLRQRICKSS ENSP00000312082/1-1059 KTVFVLTKKYAKSWNFKTAFYLALQRLMDENMDVIIFILLEPVLQHSQYLRLRQRICKSS ENSCPOP00000017959/1-1035 KTIFVLTKKYAKSWNFKTAFYLALQRLMDENMDVILFILLEPVLQHSQYLRLRRRICKSS XP_004871066.1/1-1035 KTIFVLTKKYAKSWNFKTAFYLALQRLMDENMDVILFILLEPVLQHSQYLRLRRRICKSS **:********************************:*********:*******:****** ENSMUSP00000107793/1-1032 ILQWPNNPKAENLFWQSLKNVVLTENDSRYDDLYIDSIRQY ENSRNOP00000066040/1-1029 ILQWPNNPKAENLFWQSLKNVVLTENDSRYDNLYIDSIRQY ENSP00000312082/1-1059 ILQWPDNPKAEGLFWQTLRNVVLTENDSRYNNMYVDSIKQY ENSCPOP00000017959/1-1035 ILQWPDNPKAEGLFWQSLKNVVLTENDSRYNNLYVDSIRQY XP_004871066.1/1-1035 VLQWPDNPKAEGLFWQSLKNVVLTENDSRYNNLYVDSIRQY :****:*****.****:*:***********:::*:***:**