CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000131624/1-947 --------------------------------MLCLDPLGTEWD----SKDLDGKEEPWK ENSRNOP00000062149/1-950 ---------------------------------LCLDPLGTEWDHPLGSKDLDGEEEPWK ENSP00000389009/1-950 --------------------------------MLSLDPSGPEWDCPLGSKDLE-EEGPWG ENSCPOP00000017754/1-980 PGLLQARELQGVSVPTWVTLRHPVA---LCRRQLSLDPLGPEWDRPLGSKDLDGEESPER XP_004852297.1/1-967 ----------------MYFSAHPAKSYHFCPPQLSLDPLGPKWDCPLGPKDLNGEEGPWR *.*** *.:** .***: :* * ENSMUSP00000131624/1-947 SGAGLPPTGCFPGPWRQDISLDCKGSPEETEARAWTVYYYGLLQSCLQQAGLPETQDRSQ ENSRNOP00000062149/1-950 GGAGLPPTDCFPGPWRQDVSLDCKGSPEEAEARAWTVYYYGLLQSCLQQAGLPETQDRSQ ENSP00000389009/1-950 GGSGLPPTGCFPGSWRQDVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRGQ ENSCPOP00000017754/1-980 EGSGLPPISCFPGSWRQDVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRSQ XP_004852297.1/1-967 GGSGLPPISCFPGSWRQDVGLDCKGSPEGAEARAWTVYYYSLLQSCLQQAGLPETQDRSQ *:**** .****.****:.******** :**********.*****************.* ENSMUSP00000131624/1-947 APRTGCPGAEVTLCILGSPSTFLSLLLEGGVQSPGNMLLCLSPAWLMKVATPGQEGEAVL ENSRNOP00000062149/1-950 APRTGCPGAEVTLCILGSPSTFLSLLLEGGVQSPGNMLLCLSPAWLMKVASAGQEGEADL ENSP00000389009/1-950 VPRTGCPGAEVTLCVLGSPSTFLPVLLEGGVQSPGNMLLCLSPAWLMKVPAPGQPGEAAL ENSCPOP00000017754/1-980 VPHTGCPGAEVTLCILGSPSTFLSVLLEGGVQSPGNMLLCLSPAWLMKVPASGQLGEAAL XP_004852297.1/1-967 VPHTGCPGAEVTLCILGSPSTFLSVLLEGGVQSPGNMLLCLSPAWLTKVPAPGELGEAAL .*:***********:********.:********************* **.:.*: *** * ENSMUSP00000131624/1-947 LVSKAVSFYPGGLTFLDDFVPPRHATYFLAGLGPESGRGKEAAELARNLTCPTGTSSELS ENSRNOP00000062149/1-950 LVSKAVSFYPGGLTFLDDFVPPRHATYFLAGLGPEFGHSKEAAELARHLTCPTGGSSELA ENSP00000389009/1-950 LVSKAVSFHPGGLTFLDDFVPPRRATYFLAGLGLGPGRGREAAELARDLTCPTGASAELA ENSCPOP00000017754/1-980 LVSKAVSFYPGGLTFLDDFVPPRRATYFLAGLGLGAGRGREAAELARNLTCPTGASVELA XP_004852297.1/1-967 LVSKAVSFHPGGLTFLDDFVPPRRATYFLAGLGLGSGQGREAAELARNLTCPTGASAELA ********:**************:********* *:.:*******.****** * **: ENSMUSP00000131624/1-947 QLLENRLLMRWLLSQQSGVAVPATLAFTYRPPGLLRGGDASPGLRLVELSGKEGQETLVK ENSRNOP00000062149/1-950 RLLEDRLLMRWLLSQQSGVAVPATLAFTYRPPGLLRGGDTSPGLRLVELSGKEGQETLVK ENSP00000389009/1-950 RLLEDRLLTRQLLAQQGGVAVPATLAFTYKPPGLLRGGDASLGLRLVELSGKEGQETLVK ENSCPOP00000017754/1-980 RLLEDRLLMRQLLSQQGCVAVPATLAFTYKPPGLLQGGDASPGLRLVELSGKEGQETLVT XP_004852297.1/1-967 RLLEDRLLMRQLLSQQSQVAVPATLAFTYKPPRILQGGDTSPGLRLVELSGKEGQETLVK :***:*** * **:**. ***********:** :*:***:* *****************. ENSMUSP00000131624/1-947 EEVEAFVHSEALGDASQVAVRLSGCRWRGQQALPLHLRVEPSTVVNTVLGLLEKLEEEES ENSRNOP00000062149/1-950 EEVEAFVHSKALGDASQVAVRLSGWRWRGQQVLPLHLQEEPSTVVNTVLGLLEKLEEEES ENSP00000389009/1-950 EEVEAFLRSEALGDILQVAVKLSGWRWRGRQAWRLHPRAELGAVVDTVLALLEKLEEEES ENSCPOP00000017754/1-980 EEVGAFLQSEALGDAVQVAVKPSGWRWRGRQALCLHPRVELDAVVDTVLALLEKLEEEES XP_004852297.1/1-967 EEVGAFLHSEALGDAQQVAVKLSGWRWRGRQSLCLHPRVELGAVVDTVLALLEKLEEEES *** **::*:**** ****: ** ****:* ** : * .:**:***.********** ENSMUSP00000131624/1-947 VLVEAMCPPVRLPLPGGPAPGPELAVRICAVVCRIQGDRPLLSKVVCGVGRGDRPVRHHY ENSRNOP00000062149/1-950 VLVEAMCPPVRLPLPGSPAPGPELAVRICAVVCRIQGDRPLLSKVVCGVGRGDQPVRHHY ENSP00000389009/1-950 VLVEAVYPPAQLPCSDGPSPGPGLAVRICAVVCRTQGDRPLLSKVVCGVGRGDRPLRHHN ENSCPOP00000017754/1-980 VLVEAMCPPAQLPFPGGPSPSREMAVRICTVVCRTQGDRPLLSKVVCGVGREDRPPRHQN XP_004852297.1/1-967 VLVEAMCPPARLPFPGSPSTSPEMAMRICAVVCRTQGDRPLLSKVVCGVGRGDRLLRHQN *****: **.:** ...*:.. :*:***:**** **************** *: **: ENSMUSP00000131624/1-947 TLPRTLRVALAQCGLEEEAQVALLEQGIKEAAEGALAAVLALEAGLSVEQRGGRQVHTDF ENSRNOP00000062149/1-950 TLPRSLGVALAQCGLEEEAQVALLEQGIKEAAEAALAAVLALEAGLSVEQRGGRQVHTDF ENSP00000389009/1-950 SLPRTLEVALAQCGLGEEAQVAAVRQRVKAAAEAALAAVLALEAGLSAEQRGGRRAHTDF ENSCPOP00000017754/1-980 SLPRTLEVALAQCGLSEAAQVAAVRQRVKEAAEAVLAAVLALEAGLSAEQRGGRRACTDF XP_004852297.1/1-967 SLPRTLEVGLAQCGLSEATQVVAVRQRVKEAAEAVLAAVLALEAGLSAEQRGGRRARTDF :***:* *.****** * :**. :.* :* ***..************.******:. *** ENSMUSP00000131624/1-947 LGVDLVLTVIGRTLTPVVLKLNSGLCLEACGALEGLWAVPRLRRSAEEAAAAPLVETMLR ENSRNOP00000062149/1-950 LGVDFVLTVVGRTLTPVVLKLNSGLCLETCGALEGLWAMPRLRRSAEEAAAAPLVETMLR ENSP00000389009/1-950 LGVDFALTAAGGVLTPVALELNGGLCLEACGALEGLWAAPRLGPAADEAVAAPLVETMLR ENSCPOP00000017754/1-980 LGVDFALTVSGRALTPVALELNSSLCLEACGTLEGLWAAPRLGLAAEEAAAAPLVETMLR XP_004852297.1/1-967 LGVDFALTVSGRALTPVALELNSGLCLEACGMLEGLWAAPRLGPAAEEAAAAPLVETMLR ****:.**. * .****.*:**..****:** ****** *** :*:**.********** ENSMUSP00000131624/1-947 RSGRHLMDGKQLLVIGAGGVSKKFVWEAARDYGLTLHLVESDPNHFASQLVQTFIHFDVT ENSRNOP00000062149/1-950 RSGRHLMDGKQLLVIGAGGVSKKFVWEAAQDYGLKLHLVESDPNHFASQLVQTFIHFDVT ENSP00000389009/1-950 RSARCLMEGKQLLVVGAGGVSKKFVWEAARDYGLQLHLVESDPNHFASQLVQTFIHFDMT ENSCPOP00000017754/1-980 RSARYLMEGKQLLLVGAGGVSKKFVWEAARDYGLKLHLVESDPNHFASQLVQTFIHFDVT XP_004852297.1/1-967 RSARYLMEGKQLLLVGAGGVSKKFVWEAARDYGLKLHLVESDPNHFASQLVQTFIHFDVT **.* **:*****::**************:**** ***********************:* ENSMUSP00000131624/1-947 EHRRDEENALLLAELVRARNLKLDGCFSFWDDCLVLTALLCRELGLPCSPPAAMCLAKQK ENSRNOP00000062149/1-950 EHRRDEENARLLAELVRARNLKLDGCFSFWDDCLVLTALLCRELGLPCSPPAAMCLAKQK ENSP00000389009/1-950 EHRRDEENARLLAELVRARGLKLDGCFSYWDDCLVLTALLCQELGLPCSSPAAMRLAKQK ENSCPOP00000017754/1-980 DHRRDEENARLLAELVRARGLQLDGCFSYWDDCLVLTALLCRELGLPCCPPAAMCLAKQK XP_004852297.1/1-967 EHRKDEENARLLAELVRARGLQLDGCFSYWDDCLVLTALLCQELGLPCSPPAAVCLAKQK :**:***** *********.*:******:************:******..***: ***** ENSMUSP00000131624/1-947 SRTQLHLLRCQGPPWPSTSLHAVACCPLENEADVERAIYQVPLPGVMKLEFGSGAVGVQL ENSRNOP00000062149/1-950 SRTQLHLLRCQGPPWPSTSLHAVACCPLESEADVERAIYQVPLPGVMKLEFGSGAVGVQL ENSP00000389009/1-950 SLTQLHLLHHHGPPWPAPSLHAVPCCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRL ENSCPOP00000017754/1-980 SRTQLHLSRHHGPPWPAPSLHAVACCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVQL XP_004852297.1/1-967 SHTQLHLSHCHGPPWPAPSLHAVACCPLESEADVERAVHQVPLPGVMKLEFGAGAVGVRL * ***** : :*****:.*****.*****.*******::*************:*****:* ENSMUSP00000131624/1-947 VKDGPQCREHFSRILHDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVVFGGRLLAA ENSRNOP00000062149/1-950 VKDGPQCHEHFSRILHDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVVFGGRLLAA ENSP00000389009/1-950 VEDAPQCHEHFSRITRDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVLFGGRLLAA ENSCPOP00000017754/1-980 VEDASQCHEHFSRITRDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVVFGGRLLAA XP_004852297.1/1-967 VEDAPQCHEHFSRISRDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVVFGGRLLAA *:*..**:****** :***********************************:******** ENSMUSP00000131624/1-947 FVSDNGPTRLPGFTETAACMPTGLAPEQEAQVVQAAFRCCLGCGLLDGVFNVELKMTGAG ENSRNOP00000062149/1-950 FVSDNGPTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKMTGAG ENSP00000389009/1-950 FVSDNGPTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAG ENSCPOP00000017754/1-980 FVSDNGPTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAG XP_004852297.1/1-967 FVSDNGPTRLPGFTETAACMPTGLAPEQEAQMVQAAFRCCLGCGLLDGVFNVELKLTGAG *******************************:***********************:**** ENSMUSP00000131624/1-947 PRLIEINPRMGGFYLRDWILELYGVDLLLASTMVACGLQPALPAHPRARGYLVGIMCLVS ENSRNOP00000062149/1-950 PRLIEINPRMGGFYLRDWILELYGVDLLLASAMVACGLQPALPAHPRARGYLVGIMCLVS ENSP00000389009/1-950 PRLIEINPRMGGFYLRDWILELYGVDLLLAAVMVACGLRPALPTRPRARGHLVGVMCLVS ENSCPOP00000017754/1-980 PRLIEINPRMGGFYLRDWILELYGVDLLLAAAMVACGLRPALPTHPHARGHLVGVMCLVS XP_004852297.1/1-967 PRLIEINPRMGGFYLRDWILELYGVDLLLAAAMVACGLRPALPTHPHARGHLVGIMCLVS ******************************:.******:****::*:***:***:***** ENSMUSP00000131624/1-947 QHLQLLSSPSSRETLQTLHDQGQLRLNLLEEALIPGQYEEPYCNVACAGPSPAEACHRLL ENSRNOP00000062149/1-950 QHLQLLSSPGSRETLQALHDQGQLRLNLLEEALIPGQYEEPYCNVACAGASPAEARHRLL ENSP00000389009/1-950 QHLQALSSTASRETLQALHDRGLLRLNLLEEALVPGEYEEPYCSVACAGPSPTEARLRLL ENSCPOP00000017754/1-980 QHLQALSSTASRETLQALHDQGLLRLNMLEEALVPGEYEEPYCSVACAGSSPAEARLRLL XP_004852297.1/1-967 QHLQALSSTASRETLQALHDQGLLRLNLLEEALVPGEYEEPYCSVACAGSSPAEARLRLL **** ***..******:***:* ****:*****:**:******.*****.**:** *** ENSMUSP00000131624/1-947 GICQGLGIDRPNYPVAHFLSHFK ENSRNOP00000062149/1-950 GICQGLGIDRPNYPVAHFLSHFK ENSP00000389009/1-950 GLCQGLGIDGPSYPVAHFLSHFK ENSCPOP00000017754/1-980 GLCQGLGIDGPNYPVAHFLSHFK XP_004852297.1/1-967 GLCQGLGIDGPNYPVAHFLSHFK *:******* *.***********