CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000106361/1-1203 -----MPATNQGWPEDFGFQLGGSGPCFVIEVAEGSSAHAGGLRPGDQILEVEGLAVGGL ENSRNOP00000039762/1-1024 ------------------------MSC--------------------------------- ENSP00000397351/1-1211 MATTATPATNQGWPEDFGFRLGGSGPCFVLEVAKGSSAHAGGLRPGDQILEVEGLAVGGL XP_004840490.1/1-1206 -----MPTTNQGWPEDFGFQLGGSCPCFVLEVAEGSSAHAGGLRPGDQIVEVEGLAVGGL ENSCPOP00000017035/1-1163 -----MPATNQGWPEDFGFRLGGSGPCFVLEVAEGSSAHAGGLRPGDQIVEVEGVAVGGL .* ENSMUSP00000106361/1-1203 SRERIVRLARRCPRVPPSLGVLPGPEG------GPTALTAAWLTRRFGRSLPLSRELLRL ENSRNOP00000039762/1-1024 ------------------------------------------------------------ ENSP00000397351/1-1211 SRERLVRLARRCPRVPPSLGVLPAPDGGPGPGSGPAAPTTVLRAPRCGRGLALGRELLRL XP_004840490.1/1-1206 SRERLVSLARRCPRVPPSLGVLPGPDG------GPAALTTALRAARSGRSLALGRELLRL ENSCPOP00000017035/1-1163 SRERLLSLARRCPRVPPSLGVLPGPDG------GPPALTSALLAASSGRGLALGRELLRV ENSMUSP00000106361/1-1203 AGGPRPDAVHRERRRKAQEFSCQVDDILGDRLTAKEQVFTALKQFAAEQRVDELVWTLTL ENSRNOP00000039762/1-1024 ------------------------------------------------------------ ENSP00000397351/1-1211 AGRKRPDAVHRERRRKAQEFSRKVDEILGDQPTAKEQVFAALKQFAAEQRVDDLVWTLTL XP_004840490.1/1-1206 TRRKGPDAVHRERRLKAQEFSRKVDEILGDQPAAKEQVFAALKQFAAEQRVDDLVWALTL ENSCPOP00000017035/1-1163 AGRKRPESVHRERRHKAQEFSRKVDEILGDQPAAKKQVFAALKQFAAEQRVDDLVWALTL ENSMUSP00000106361/1-1203 VLPSEAQGPVLDNLRIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPE ENSRNOP00000039762/1-1024 -------------LGIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPE ENSP00000397351/1-1211 ALPREACGPLLDNLRIFIPKKHRARFDEVVSQGLLGKLCRARRAQGAQRLRRSRSEERPE XP_004840490.1/1-1206 VLPHEARGPLLDNLRIFIPKKHRARFDEVVSQGLLGKLCRARRTQGAQRLRRSRSEERPE ENSCPOP00000017035/1-1163 VLPHETHRPLLDNLRIFIPKKHRARFDEVVSQGLLGKLCRARRTQGAQRLRRSRSEERPE * ****************************:**************** ENSMUSP00000106361/1-1203 RLLVSTRASAAPRRPDEPPPRKATSLLGGRTGPGGPRRTVRVYKGNKSFGFTLRGHGPVW ENSRNOP00000039762/1-1024 RLLVSTRASAAPRRPDEPPPRKAASLLGGRTGPGGPRRTVRVYKGNKSFGFTLRGHGPVW ENSP00000397351/1-1211 RLLVSTRASAPPRRPDEPPPRRASLLVGGLAGPGGARRTVRVYKGNKSFGFTLRGHGPVW XP_004840490.1/1-1206 RLLVSTRASAAPRRPDEPPPRKAASLLGGRAGPGGARRTVRVYKGNKSFGFTLRGHGPVW ENSCPOP00000017035/1-1163 RLLVSTRASAAPRRPDEPPPRKAASLLGGRADPGGARRTVRVYKGNKSFGFTLRGHGPVW **********.**********:*: *:** :.***.************************ ENSMUSP00000106361/1-1203 IESVLPGSPAENASLKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGPVPFA ENSRNOP00000039762/1-1024 IESVLPGSPAENASLKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGPVPFA ENSP00000397351/1-1211 IESVLPGSPADNAALKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFA XP_004840490.1/1-1206 IESVLPGSPADSAALKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFA ENSCPOP00000017035/1-1163 IESVLPGSPADNAALKSGDRILFLNGLDMRNCSHDKVVSMLQGSGAMPTLVVEEGLVPFA **********:.*:***************************************** **** ENSMUSP00000106361/1-1203 S-DSDSLDSPTRASALTSLQWVADILPSSIRVQGRTFSQQLDHLLTPPERYGVCRALERF ENSRNOP00000039762/1-1024 S-DSDSLDSPTRASALTSLQWVADILPSSIRVQGRTFSQQLDHLLTPPERYGVCRALESF ENSP00000397351/1-1211 S-DSDSLDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESF XP_004840490.1/1-1206 S-DSDSLDSPNPSSAVTSLQWVAEILPSSIRVQGRTFSQQLEHLLRPPERYGVCRALESF ENSCPOP00000017035/1-1163 SADSDSLDSPNPSSALTSLQWVAEILPSSIRVQGRTFSQQLEHLLTPPERYGVCRALESF * ********. :**:*******:*****************:*** ************ * ENSMUSP00000106361/1-1203 FQHRNIDTLIVDVYPVLDTPAKQVLWQFLYQLLTYEEQELCQEKIACFLGYTAMT-EP-- ENSRNOP00000039762/1-1024 FQHRSIDTLIVDVYPVLDTPAKQVLWQFLYQLLTYEEQELCQEKIACFLGYTAIT-EP-- ENSP00000397351/1-1211 FQHRNIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMTAEP-- XP_004840490.1/1-1206 FQHRNIDTLIIDVYPVLDTPAKQLLWQFIYQLLTYEEQELCQEKIACFLGYTAMT-EPEL ENSCPOP00000017035/1-1163 FQHRNIDTLIVDVYPVLDTPAKQVLWQFIYQLLTYEEQELCQEKIACFLGYTAMT-EA-- ****.*****:************:****:************************:* *. ENSMUSP00000106361/1-1203 ESSLDLEPE--STPEPTPEPQPRSSLRASSMCRRSLRSQGLETSLSCGPGDCPEMPLPLI ENSRNOP00000039762/1-1024 ESSLDLEPE--STPEPTPEPQPRSSLRASSMCRRSLRSQGLEASLSCGPGDCSEMPLPLI ENSP00000397351/1-1211 EPELDL------ESEPTPEPQPRSSLRASSMCRRSLRSQGLEAGLSCGPSECPEMPLPLI XP_004840490.1/1-1206 EPELDLEPESELEPEPTPEPQPRISLRASSMCRRSLRSQGLEASLSCGLSDCPEMPLPLI ENSCPOP00000017035/1-1163 EDKCSI--A--LPCPPTPEPQPRSSLRASSMCRRSLRSQGLEASLSCDPSDCPEMPLPLI * . .: ******** ******************:.***. .:*.******* ENSMUSP00000106361/1-1203 PGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKIGTMSKSRASPPVPSLVGTSG ENSRNOP00000039762/1-1024 PGERQAGDGTSLPETPNPKMMSAVYAELESRLNSGFKGKIGTVSKSRASPPVPSLVGTSG ENSP00000397351/1-1211 PGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKMGTVSKSRASPPGPSPAVTTG XP_004840490.1/1-1206 PGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKMGTVSKSQASPAVPSLVGTAA ENSCPOP00000017035/1-1163 PGERQAGDGTSLPETPNPKMMSAVYAELESRLNSSFKGKMGTVSKSRASPPVPSLVGTAS **********************************.****:**:***:***. ** . *:. ENSMUSP00000106361/1-1203 PRTLSGVSWPSDRLLPSPCYDPLCSGGLASPSSSESHPYASLDSSRAPSPQPGLGSIHAD ENSRNOP00000039762/1-1024 PRTLSGVSWPGDRLLPSPCYDPLCSGGLASPSSSESHPYASLDSSRAPSPQPGLGSIHPD ENSP00000397351/1-1211 PRTLSGVSWPSERLLPSPCYHPLCSGGLASPSSSESHPYASLDSSRAPSPQPGPGPICPD XP_004840490.1/1-1206 PRTLSSISWPREQLFPSPCYDPLCSGGLGSPSSSESHPYASLDSSRAPSPQPGPAPACPD ENSCPOP00000017035/1-1163 -RTLSNISWPSERLLPSPCYDPLCSGGLASPSSSESHPYASLDSSRAPSPQPGPGPTCPD ****.:*** ::*:*****.*******.************************ .. .* ENSMUSP00000106361/1-1203 SPPSPDPIRPPSRRKLFAFSRPVRSRDTDRFLDALSEQLGPRLSIVDDFLTPENDYEEMS ENSRNOP00000039762/1-1024 SPPSPDPIRPPSRRKLFAFSRPVRSRDTDRFLDVLSEQLGPRVTIVDDFLTPENDYEEMS ENSP00000397351/1-1211 SPPSPDPTRPPSRRKLFTFSHPVRSRDTDRFLDVLSEQLGPRVTIVDDFLTPENDYEEMS XP_004840490.1/1-1206 SPPSPDLARPPSHRKLFTFSRPVRSRDTDRFLDVLSEQLGPPVTIVDDFLTPENDYEEMS ENSCPOP00000017035/1-1163 SPPSPDLARPSSRRKLFTFAHPTRSRDTDRFLDVLSEQLGPRVTIVDDFLTPENDYEEMS ****** **.*:****:*::*.**********.******* ::**************** ENSMUSP00000106361/1-1203 FHDDQGSFVTNERSSASECVSSSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDPKPSS ENSRNOP00000039762/1-1024 FHDDQGSFVTNERSSASECVSSSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDPKPSS ENSP00000397351/1-1211 FHDDQGSFVTNERSSASDCISSSEEGSSLTYSSISDHIPPPPLSPPPPPPLPFHDAKPSS XP_004840490.1/1-1206 FHDDQGSFVTNERSSASECISSSEEGSSLTYSSISDHIPPPPLS-PPPPPLPFHDPKPSS ENSCPOP00000017035/1-1163 FHDDQGSFVTNERSSASECISSSEEGSSLTYSSIS---------------------KPNS *****************:*:*************** **.* ENSMUSP00000106361/1-1203 RTSDGPRGPPQSLTKPLTQINHPVPPPPPPPLPPPVPCAPPMLSRGVGHRRSETSHMSVK ENSRNOP00000039762/1-1024 RTSDGPRGPPQSLTKPLTQISHPVPPPPPPPLPPPVPCAPPMISRGVGHRRSETSHMSVK ENSP00000397351/1-1211 RSSDGSRGPAQALAKPLTQLSHPVPPPPPPPLPPPVPCAPPMLSRGLGHRRSETSHMSVK XP_004840490.1/1-1206 RASDTPRGPPQALAKPLTQLSHPVPPPPPPPLPPPVPCAAPMLSRGWGHRRSETSHMSVK ENSCPOP00000017035/1-1163 RTSEPSRGPAQALAKPLTQLSHPVP-----------------LSRGLGHRRSETSHMSVK *:*: .***.*:*:*****:.**** :*** ************* ENSMUSP00000106361/1-1203 RLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPPKPVPGPEPFRKKEV ENSRNOP00000039762/1-1024 RLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPPKPVPGPEPFRKKEV ENSP00000397351/1-1211 RLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPAKPVPGPEPFRKKEV XP_004840490.1/1-1206 RLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPVKPVPGPEPFRKKEV ENSCPOP00000017035/1-1163 RLRWEQVENSEGTIWGQLGEDSDYDKLSDMVKYLDLELHFGTQKPVKPVPGPEPFRKKEV ********************************************* ************** ENSMUSP00000106361/1-1203 VEILSHKKAYNTSILLAHLKLTPGELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQ ENSRNOP00000039762/1-1024 VEILSHKKAYNTSILLAHLKLTPGELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQ ENSP00000397351/1-1211 VEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQ XP_004840490.1/1-1206 VEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQ ENSCPOP00000017035/1-1163 VEILSHKKAYNTSILLAHLKLSPAELRQVLMSMEPRRLEPAHLAQLLLFAPDADEEQRYQ *********************:*.************************************ ENSMUSP00000106361/1-1203 AFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELK ENSRNOP00000039762/1-1024 AFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELK ENSP00000397351/1-1211 AFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELK XP_004840490.1/1-1206 AFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELK ENSCPOP00000017035/1-1163 AFREAPGRLSEPDQFVLQMLSVPEYKTRLRSLHFQATLQEKTEEIRGSLECLRQASLELK ************************************************************ ENSMUSP00000106361/1-1203 NSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSL ENSRNOP00000039762/1-1024 NSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSL ENSP00000397351/1-1211 NSRKLAKILEFVLAMGNYLNDGQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSL XP_004840490.1/1-1206 NSRKLAKILEFVLAMGNYLNDSQPKTSKTTGFKINFLTELNSTKTVDGKSTFLHILAKSL ENSCPOP00000017035/1-1163 NSRKLAKILEFVLAMGNYLNDSQPKTNKTTGFKINFLTELNSTKTVDGKSTFLHILAKSL *********************.****.********************************* ENSMUSP00000106361/1-1203 SQHFPELLGFAQDLPTVPLAAKVNQRALTGDLADLHDTVSEIQVACQSMAPSSEDRFAVV ENSRNOP00000039762/1-1024 SQHFPELLGFAQDLPTVPLAAKVNQRALTVDLADLHDTVSEIQVACQSMVPSSEDRFAVV ENSP00000397351/1-1211 SQHFPELLGFAQDLPTVPLAAKVNQRALTSDLADLHGTISEIQDACQSISPSSEDKFAMV XP_004840490.1/1-1206 SQHFPELLGFSQDLPTVPLAAKVNQRALTGDLADLHGTISEIQAACQSMSPSSEDRFAVV ENSCPOP00000017035/1-1163 SQHFPELLGFAQDLPTVPLAAKVNQRALTGDLADLHGTISEIQAACQSMSPSSEDRFAVV **********:****************** ******.*:**** ****: *****:**:* ENSMUSP00000106361/1-1203 MASFLETAQPALRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFSEFMSKFERAL ENSRNOP00000039762/1-1024 MTSFLETAQPALRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFSEFMSKFERAL ENSP00000397351/1-1211 MSSFLETAQPALRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFAEFMSKFERAL XP_004840490.1/1-1206 MASFLETAQPTLRALDGLQREAMEELGKALAFFGEDSKATTSEAFFGIFVEFMSKFERAL ENSCPOP00000017035/1-1163 MASFLETAQPALRALDGLQHEAMEELGKALAFFGEDSKATTSEAFFGIFSEFMSKFERAL *:********:********:***************************** ********** ENSMUSP00000106361/1-1203 SDLQAGDGPRSSGMVSPLAW ENSRNOP00000039762/1-1024 SDLQAGDGPRSSGMVSPLAW ENSP00000397351/1-1211 SDLQAGEGLRSSGMVSPLAW XP_004840490.1/1-1206 SDLQAGEGPRGSGMTSPLAW ENSCPOP00000017035/1-1163 SDLQAGEGPRSSGMTSPLAW ******:* *.***.*****