CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000030539/1-1038 MASESVKVVVRCRPMNKRERELSCQSVVTVDSARGQCFIQNPGAADEPPKQFTFDGAYYI ENSRNOP00000020215/1-1032 MASESVKVVVRCRPMNKRERELNCQSVVTVDCARGQCFIQNPGAADEPPKQFTFDGAYYI ENSP00000247986/1-1029 MASEAVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHV ENSCPOP00000016545/1-1019 MASESVKVVVRCRPMNQRERELNCQSVVTVDSARGQCFIQNPGAAEQPPKQFTFDGAYYT XP_004850533.1/1-995 MASEMVKVVVRCRPMNQRERELNCQPVVTVDSARGQCFIQNPGAAAEPPKQFTFDGAYHM **** ***********:***** **.*****.**.** ******* :***********: ENSMUSP00000030539/1-1038 EHFTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPCQRGIIPRAFEH ENSRNOP00000020215/1-1032 EHFTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPCQRGIIPRAFEH ENSP00000247986/1-1029 DHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEH ENSCPOP00000016545/1-1019 EHFTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPCQRGIIPRAFEH XP_004850533.1/1-995 EHFTEQIYNDIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDLPSQRGIIPRAFEH :*.******:************************************ *.*********** ENSMUSP00000030539/1-1038 VFESVQCAENTKFLVRASYLEIYNEDVHDLLGADTKQRLELKEHPEKGVYVKGLSMHTVH ENSRNOP00000020215/1-1032 VFESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQRLELKEHPEKGVYVKGLSMHTVH ENSP00000247986/1-1029 VFESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVH ENSCPOP00000016545/1-1019 VFESVQCAEDTKFLVRASYLEIYNEDVHDLLGADTKQKLELKEHPEKGVYVKGLSMHTVH XP_004850533.1/1-995 VFESVQCAEDTKFLVQASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVHVKGLSMHMVH *********:*****:***********:*********:***********:******* ** ENSMUSP00000030539/1-1038 NVAQCERVMETGWKNRAVGYTLMNKDSSRSHSIFTINIEIYAVDERGKDHLRAGKLNLVD ENSRNOP00000020215/1-1032 NVAQCERVMETGWKNRAVGYTLMNKDSSRSHSIFTINIEIYAVDERGKDHLRAGKLNLVD ENSP00000247986/1-1029 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVD ENSCPOP00000016545/1-1019 SVAQCERIMETGWKNRAVGYTLMNTDSSRSHSIFTISIEIYAVDERGKDHLRAGKLNLVD XP_004850533.1/1-995 SVAQCERIMETGWKNRAVGYTLMNKDSSRSHSIFTISIEIYAVDEQGEDHLRAGKLNLVD .*****::********:*******.***********.**: ****:*:************ ENSMUSP00000030539/1-1038 LAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHIPYRDSKLTRLLQDSL ENSRNOP00000020215/1-1032 LAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHIPYRDSKLTRLLQDSL ENSP00000247986/1-1029 LAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSL ENSCPOP00000016545/1-1019 LAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHIPYRDSKLTRLLQDSL XP_004850533.1/1-995 LAGSERQSKTGVSGERLKEATKINLSLSALGNVISALVDGRCRHIPYRDSKLTRLLQDSL ***********.:*****************************:*:*************** ENSMUSP00000030539/1-1038 GGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIKNKPRINEDPKDALLREYQEEIKRL ENSRNOP00000020215/1-1032 GGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIKNKPRINEDPKDALLREYQEEIKRL ENSP00000247986/1-1029 GGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEEIKKL ENSCPOP00000016545/1-1019 GGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIKNKPRINEDPKDALLREYQEEIKRL XP_004850533.1/1-995 GGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIKNKPRINEDPKDALLRQYQEEIKKL ***********************************:***************:******:* ENSMUSP00000030539/1-1038 KAILAQQMGPGNLSALLSTQTPPGPVQSEEKLLSPTTV-QQDTEAEKQLIREEYEERLAR ENSRNOP00000020215/1-1032 KAILAQQMGPGNLSALLSTQTPSGPVHPEEKLPSPTTV-QQDTEAEKQMIREEYEERLAR ENSP00000247986/1-1029 KAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVI-QHDVEAEKQLIREEYEERLAR ENSCPOP00000016545/1-1019 RAILEQQLSPGGLSALLSSQLPLSPAQVEEKLLSSPGIQQQDVETEKQLIREEYEERLAR XP_004850533.1/1-995 RAILAQQLSPGGLSALLCGQLPLSPAQVEEKLLSSPVV-PQDMEAEKQLIREEYEERLAQ :*** **:.*..*****. * * .*.: **** . . : :* *:***:**********: ENSMUSP00000030539/1-1038 LKADYEAEQESRVRLQEDITAMRNSYDVKLSTLQENLRKEKETEAILKAEVLCKTEVMSR ENSRNOP00000020215/1-1032 LKADYEAEQESRVRLQEDITAMRNSYDVKLSTLQENLRKEKETEAVLKAEVLCKTEVMSR ENSP00000247986/1-1029 LKADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLR--KETEAVLQVGVLYKAEVMSR ENSCPOP00000016545/1-1019 LRADYEAEQESRARLEEDMTAMRNSYDVQLSTLQENLR--KGTEAILKAEVLHNAEVLSR XP_004850533.1/1-995 LKADYEVEQESRARLEEDITAMRNSYDVQLSMLQENLR--KGTETVLKAEVLHNAEVMSR *:***:.*****.**:**:*********:** *:**** * **::*:. ** ::**:** ENSMUSP00000030539/1-1038 AELASGPEYSPPLQYETAVKPTILSMPDMPPSGKVTKSQAPLAFEE-PHGETSRSEFSFE ENSRNOP00000020215/1-1032 AEVTSGPEYSPPLQYETAVKPTVLSMPDMLPRGEVTRSQAPLTSEE-PNMEPSRSEV-FE ENSP00000247986/1-1029 AEFASSAEYPPAFQYETVVKPKVFSTTDTLPSDDVSKTQVSSRFAELPKVEPSKSEISLG ENSCPOP00000016545/1-1019 AEFASRCEHTSDFQLEASRKSTIFSVPDTLHWDAVSNTQISTRFEELRRAEPSKSEISLR XP_004850533.1/1-995 AEFANMSEHVPAFQFEAAVKPSIFSIPDPLPRDEVSNTQISPRFEELRRAEPSKSEISLR **.:. *: . :* *: *..::* .* . *:.:* . * . *.*:**. : ENSMUSP00000030539/1-1038 SNECSTLEDSATSEAFPGPEEFSNMEFSMAAALTESRYLPEEYLGGQEAAASPLEAERYV ENSRNOP00000020215/1-1032 SNESSNLEDSSMSEAYPGPEELSNVEFSMPGVLAESRYFPDEYL-NPEAAGCPLEAEHSV ENSP00000247986/1-1029 SSESSSLEETSVSEAFPGPEEPSNVEVSMPTEESRSRYFLDECL-GQEAAGHLLGEQNYL ENSCPOP00000016545/1-1019 SSESSMLEESFMSEALPVPEELSNLELPGPEVGSQSKYFLDKSL-SQENSGTQLEGENYI XP_004850533.1/1-995 SSESSMLEESSMSEALPGPEELSNLELCGPEVRSQSKYFLNEDP-GQEDSETRLEGENYI *.*.* **:: *** * *** **:*. . :.*:*: :: . * : * :. : ENSMUSP00000030539/1-1038 QENEPSLEPLRILASLQDPFAEVEAKLARLSSTVAMSDSSQTVVPQIPKQ-PSSADLLEP ENSRNOP00000020215/1-1032 Q-DEPTLEPLRILASLQDPFAEVEAKLARLSSTVAMTDLSQTVVPQVPQQ-PSSTDLLEP ENSP00000247986/1-1029 PQEEPQEVPLQGLLGLQDPFAEVEAKLARLSSTVARTDAPQADVPKVPVQVPAPTDLLEP ENSCPOP00000016545/1-1019 RVEELPLEPPQMGPSLQDPFAEVEAKLARLSSMVTRTD-----VPQVPMQHTPLTDLLEP XP_004850533.1/1-995 QVEEQPLVPPKMGLSLRDPFAEVEAKLARLSSMVARTD-----VPQVPMK---------- :* * : .*:*************** *: :* **::* : ENSMUSP00000030539/1-1038 -SDTKSEADVAVADNVVLGTEPDV-NLRVAEEVVSEAETGVWMESEAQVAHVAQVSEEAQ ENSRNOP00000020215/1-1032 -SDTKSEVD--VADNVLLRTEPDL-SMKVAEEVVSEAETGVWMESEAHVAHVAQVSEEAQ ENSP00000247986/1-1029 -SDARPEAE--AADDFPPRPEVDL-ASEVALEVVRTAEPGVWLEAQAPVALVAQ------ ENSCPOP00000016545/1-1019 IDDTRSEAE--VAADLLPSTVSDLPEIDLAPEVAEVAEPRTWMEAE-----VAQ------ XP_004850533.1/1-995 --------------------EVHL-ALEVAE--VSAAEPDTWMEAEPQMALAAQ------ .: :* . **. .*:*:: .** ENSMUSP00000030539/1-1038 PQPLLAMVSVRRESVGVEVAVLTEEELQPVDQQQVLARLQLLEQQVVGGEQAKNKDLREK ENSRNOP00000020215/1-1032 PQPLLAMASVRRESIGVEVAVLTEE-LQPVDQQQVLARLQLLEQQVVGGEQAKNKDLKEK ENSP00000247986/1-1029 PEPLPATAGVKRESVGMEVAVLTDDPLPVVDQQQVLARLQLLEQQVVGGEQAKNKDLKEK ENSCPOP00000016545/1-1019 PQPLLAT-GAQRESV--DVAVLTEVPMPGVNQQQVLARLQLLEQQVVGGEQAKNKDLKEK XP_004850533.1/1-995 PQPLLATASARRESVGVGVAVPTEELLPGVDQQQVLARLQLLEQQVVGGEQAKNKDLKEK *:** * ..:***: *** *: : *:**************************:** ENSMUSP00000030539/1-1038 HKRRKRYADERKKQLVAALQNSDEDGGDWVLLNVYDSIQEEVRAKSKLLEKMQRKLRAAE ENSRNOP00000020215/1-1032 HRRRKRYADERKKQLVAALQNSDEDSGDWVLLNVYDSIQEEVRAKSKLLEKMQKKLRAAE ENSP00000247986/1-1029 HKRRKRYADERRKQLVAALQNSDEDSGDWVLLNVYDSIQEEVRAKSKLLEKMQRKLRAAE ENSCPOP00000016545/1-1019 HRRRKRYADERKKQLVAALQNSDEDVGEWVLLNVYDSIQEEVRAKSKLLEKMQRKLRAAE XP_004850533.1/1-995 HRRRKRYADERKKQLVAALQNSEEDVGDWVLLNVYDSIQEEVRAKSKLLEKMQRKLRAAE *:*********:**********:** *:*************************:****** ENSMUSP00000030539/1-1038 VEIKDLQSEFQLEKIDYLATIRRQERDSMLFQQLLEQVQPLIRRDCNYSNLEKIRRESSW ENSRNOP00000020215/1-1032 VEIKDLQSEFQLEKIDYLATIRRQERDSMLFQQLLEQVQPLIRRDCNYSNLEKIRRESSW ENSP00000247986/1-1029 VEIKDLQSEFQLEKIDYLATIRRQERDSMLLQQLLEQVQPLIRRDCNYSNLEKILRESCW ENSCPOP00000016545/1-1019 VEIKDLQSEFELEKIDYLATIRRQERDSMLLQQLLEQVQPLIRRDCNYSNLERIRRESTW XP_004850533.1/1-995 VEIKDLQSEFELEKIDYLATIRRQERDSLLLQQLLEQVQPLIRRDCNYSNLERIRRESSW **********:*****************:*:*********************:* *** * ENSMUSP00000030539/1-1038 DEDNGFWKIPDPIILKTSLP-VVPTGTQNKPARKTSAVDSGEPHMQEEDRYKLMLSRSDS ENSRNOP00000020215/1-1032 DEDNGFWKIPEPIILKTSLP-VVPTGTQNKPARKTSAVDSGEPHMQEEDRYKLMLSRSDS ENSP00000247986/1-1029 DEDNGFWKIPHPVITKTSLPVAVSTGPQNKPARKTSAADNGEPNM-EDDRYRLMLSRSNS ENSCPOP00000016545/1-1019 DEDSGFWRIPEPVIVKTSLPVAVPTGPQTKPARKTSATDTGELTM-EEDRYKLMLSRSDS XP_004850533.1/1-995 DEDSSSWRIPEPVIVKTSLP-AVPTGPQTKPARKTSASDSREPNMQEEDRYRLMLSRSDS ***.. *:**.*:* ***** .*.**.*.******** *. * * *:***:******:* ENSMUSP00000030539/1-1038 ENIASNYFRSKRASQILSTDPMKSLTYHNSPPGLNSSLSNNSALPPTQTPEMPQPRPFRL ENSRNOP00000020215/1-1032 ENIASNYFRSKRASQILSTDPMKSLTYHNSPPGLNSSLSNSSALPPAQTPEIPQPRPFRL ENSP00000247986/1-1029 ENIASNYFRSKRASQILSTDARKSLTHHNSPPGLSCPLSNNSAIPPTQAPEMPQPRPFRL ENSCPOP00000016545/1-1019 ENIASNYFRSKRASQILSSESMKSLIHHSSSPGLSSQLSSNSAILPTQVPELPQPRPFRL XP_004850533.1/1-995 ENIASNYFRSKRASQILSTDPMKSLVHHSLSPGLSSQLSNNSTIPTTQALEMPQPRPFRL ******************::. *** :*. .***.. **..*:: .:*. *:******** ENSMUSP00000030539/1-1038 ESLDIPFSKAKRKKSKNSFGGEPL ENSRNOP00000020215/1-1032 ESLDIPFSKAKRKKSKSSFSGEPL ENSP00000247986/1-1029 ESLDIPFTKAKRKKSKSNFGSEPL ENSCPOP00000016545/1-1019 ESLDIPFTKAKRKKSKSNLGSEPL XP_004850533.1/1-995 ESLDIPFTKAKRKKIKSNLGSEAL *******:****** *..:..*.*