CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000016467/1-1049 MQKPSGLKPPGRGGKHSSPMGRTSTGSVSGSATVATTGSKEGSPLHKQASGSLSSLTTAA XP_004840084.1/1-1026 MQKPSGLKPPGRGGKHSSPMGRTSTGSASGSTIAGATSSKEGSPLHKQASGS------PA ENSP00000378500/1-1046 MQKPSGLKPPGRGGKHSSPMGRTSTGSASSSAAVAAS-SKEGSPLHKQSSGPSSS--PAA ENSMUSP00000098212/1-1047 MQKPSGLKPPGRGGKHSSPVGRPSVGSASSSVVASTSGSKEGSPLHKQASGPSSS--GAA ENSRNOP00000035734/1-1047 MQKPSGLKPPGRGGKHSSPVGRPSIGSASSSVVASASGSKEGSPLHKQASGPSSA--GAT *******************:**.* **.*.*. ..:: **********:**. .: ENSCPOP00000016467/1-1049 TTAPEKPGPKVAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDEPV XP_004840084.1/1-1026 PAAPEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDEPV ENSP00000378500/1-1046 AAAPEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPV ENSMUSP00000098212/1-1047 TTVSEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPV ENSRNOP00000035734/1-1047 TTVSEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPV .:..******.**********************************************:** ENSCPOP00000016467/1-1049 GKNDGAVGGVRYFECPALQGIFTRPSKLTRQLVAEGSGSDAHSVESLTAQNLSLHSGTAT XP_004840084.1/1-1026 GKNDGAVGGVRYFECPALQGIFTRPSKLTRQPAAEGSGSDAHSVESLTAQNLSLHSGTAT ENSP00000378500/1-1046 GKNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSGSDAHSVESLTAQNLSLHSGTAT ENSMUSP00000098212/1-1047 GKNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSGSDTHSVESLTAQNLSLHSGTAT ENSRNOP00000035734/1-1047 GKNDGAVGGVRYFECPALQGIFTRPSKLTRQPAAEGSGSDAHSVESLTAQNLSLHSGTAT ******************************* .*******:******************* ENSCPOP00000016467/1-1049 PPLASRVLPLRDSVLGSAVKTGNESGSNLSDSGSVKRGDKDLRLGDRVLVGGTKTGVVRY XP_004840084.1/1-1026 PPLASRVLPLRDSVLGSAVKTGNESGSNLSDSGSVKRGDKDLRLGDRVLVGGTKTGVVRY ENSP00000378500/1-1046 PPLTSRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRGEKDLRLGDRVLVGGTKTGVVRY ENSMUSP00000098212/1-1047 PPLTGRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRGDKDLHLGDRVLVGGTKTGVVRY ENSRNOP00000035734/1-1047 PPLTGRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRGDKDLHLGDRVLVGGTKTGVVRY ***:.**:***:***.*:********************:***:***************** ENSCPOP00000016467/1-1049 VGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAK XP_004840084.1/1-1026 VGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAK ENSP00000378500/1-1046 VGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAK ENSMUSP00000098212/1-1047 VGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAK ENSRNOP00000035734/1-1047 VGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAK ************************************************************ ENSCPOP00000016467/1-1049 AKKTKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYTRKISGTTAL XP_004840084.1/1-1026 AKKTKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTAL ENSP00000378500/1-1046 AKKTKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTAL ENSMUSP00000098212/1-1047 AKKTKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTAL ENSRNOP00000035734/1-1047 AKKTKRMAMGVSALTHSPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKISGTTAL **************************************************:********* ENSCPOP00000016467/1-1049 QEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRA XP_004840084.1/1-1026 QEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRA ENSP00000378500/1-1046 QEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRA ENSMUSP00000098212/1-1047 QEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRA ENSRNOP00000035734/1-1047 QEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRA ************************************************************ ENSCPOP00000016467/1-1049 RLLVDSVRKEKVDLSNQLEEERRKVEDLQFRVEEESITKGDLEAEQTQTQLEHARIGELE XP_004840084.1/1-1026 RLLVDSVRKEKVDLSNQLEEERRKVEDLQFRVEEESITKGDLE---TQTQLEHARIGELE ENSP00000378500/1-1046 RLLVESVRKEKVDLSNQLEEERRKVEDLQFRVEEESITKGDLE---TQTQLEHARIGELE ENSMUSP00000098212/1-1047 RLLVENVRKEKVDLSNQLEEERRKVEDLQFRVEEESITKGDLE---TQTQLEHARIGELE ENSRNOP00000035734/1-1047 RLLVENVRKEKVDLSNQLEEERRKVEDLQFRVEEESITKGDLE---TQTQLEHARIGELE ****:.************************************* ************** ENSCPOP00000016467/1-1049 QSLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELSLRRGEIEQLQQCLLHAGPPTA XP_004840084.1/1-1026 QSLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELSLRRGEIEQLQQCLLHAGPPSP ENSP00000378500/1-1046 QSLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELTLRRGEIEELQQCLLHSGPPPP ENSMUSP00000098212/1-1047 QSLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELSLRRGEIEELQHCLLQSGPPPA ENSRNOP00000035734/1-1047 QSLLLEKAQAERLLRELADNRLTTVAEKSRVLQLEEELSLRRGEIEELQHCLLQSGPPPA **************************************:*******:**:***::***.. ENSCPOP00000016467/1-1049 NDPEAAEALRLREQLLSASQEQQRESGALRDKYEAALKAYQAEVDKLRAANDKYAQEVAD XP_004840084.1/1-1026 DDPEAAEALRLREQLLSASQEQRRESGALRDKYEAALKAYQAEVDKLRAANDKYAQEVAD ENSP00000378500/1-1046 DHPDAAEILRLRERLLSASKEHQRESGVLRDKYEKALKAYQAEVDKLRAANEKYAQEVAG ENSMUSP00000098212/1-1047 DHPEAAETLRLRERLLSASKEHQRDSTLLQDKYEHMLKTYQTEVDKLRAANEKYAQEVAD ENSRNOP00000035734/1-1047 DHPEAAETLRLRERLLSASKEHQRDSTLLQDKYEHMLKTYQTEVDKLRAANEKYAQEVAD :.*:*** *****:*****:*::*:* *:**** **:**:*********:*******. ENSCPOP00000016467/1-1049 LKAKVQQATSENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKAVLE XP_004840084.1/1-1026 LKAKVQQATSENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKAVLE ENSP00000378500/1-1046 LKDKVQQATSENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKAVME ENSMUSP00000098212/1-1047 LKAKVQQATTENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKALVE ENSRNOP00000035734/1-1047 LKAKVQQATTENMGLMDNWKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKALVE ** ******:***********************************************::* ENSCPOP00000016467/1-1049 GIKMEHQLELGNLQAKHDLETAMHAKEKEGLRQKLQEAREELAGLRQHWHAQLEAQAAQH XP_004840084.1/1-1026 GIKMEHQLELGNLQAKHDLEMAVHAKEKEGLREKLQEAQEELAGLRQHWRAQLEAQAAQH ENSP00000378500/1-1046 GIKMEHQLELGNLQAKHDLETAMHVKEKEALREKLQEAQEELAGLQRHWRAQLEVQASQH ENSMUSP00000098212/1-1047 GIKMEHQLELGNLQAKHDLETAMHGKEKEGLRQKLQEVQEELAGLQQHWREQLEEQASQH ENSRNOP00000035734/1-1047 GIKMEHQLELGNLQAKHDLETAMHGKEKEGLRQKLQEAQEELAGLQQHWRAQLEEQASQH ******************** *:* ****.**:****.:******::**: *** **:** ENSCPOP00000016467/1-1049 RLELQEAQDGRRDAELRAQELEGLDVEYRGQAQAIEFLKEQIALAERKMLDYERLQRAEA XP_004840084.1/1-1026 RLELQEARDGRRNAELRAQELEGLDVEYRGQAQAIEFLKGQIALAERKMLDY-------- ENSP00000378500/1-1046 RLELQEAQDQRRDAELRVHELEKLDVEYRGQAQAIEFLKEQISLAEKKMLDYERLQRAEA ENSMUSP00000098212/1-1047 RLELQEAQDQCRDAQLRAQELEGLDVEYRGQAQAIEFLKEQISLAEKKMLDYEMLQRAEA ENSRNOP00000035734/1-1047 RLELQEAQDQCRDAQLRVQELEGLDVEYRGQAQAIEFLKEQISLAEKKMLDYEMLQRAEA *******:* *:*:**.:*** **************** **:***:***** ENSCPOP00000016467/1-1049 QSKQEAERLREKLLVAENRLQAAEAQCSAQHSHVIDSDDLSEEKIRVKETVEGLQDKLNK XP_004840084.1/1-1026 ------ERLREKLLVAENRLQAAEAQCSAQHGHVIDSDDLSEEKIRMEEMVEGLQEKLNK ENSP00000378500/1-1046 QGKQEVESLREKLLVAENRLQAVEALCSSQHTHMIESNDISEETIRTKETVEGLQDKLNK ENSMUSP00000098212/1-1047 QSRQEAERLREKLLVAENRLQAAESLCSAQHSHVIESSDLSEETIRMKETVEGLQDKLNK ENSRNOP00000035734/1-1047 QSRQEAERLREKLLVAENRLQAVESLCSAQHSHVIESNDLSEEKIRMKETVEGLQDKLNK * **************.*: **:** *:*:*.*:***.** :* *****:**** ENSCPOP00000016467/1-1049 RDKEVTALTSQTEALRAQVSALESKCKSGEKKADALLKEKRRLEAELEAVSRKTHDASGQ XP_004840084.1/1-1026 RDKEVTALTSQAEALRAQVSVLESKCKSGEKKADALLREKRRLEAELEAMSRKTHDASGQ ENSP00000378500/1-1046 RDKEVTALTSQTEMLRAQVSALESKCKSGEKKVDALLKEKRRLEAELETVSRKTHDASGQ ENSMUSP00000098212/1-1047 RDKEVTALTSQMDMLRAQVSALENKCKSGEKKIDSLLKEKRRLEAELEAVSRKTHDASGQ ENSRNOP00000035734/1-1047 RDKEVAALTSQMDMLRAQVSALENKCKSGEKKIDSLLKEKRRLEAELEAVSRKTHDASGQ *****:***** : ******.**.******** *:**:**********::********** ENSCPOP00000016467/1-1049 LLLISQELLRKERSLNELRVLLLEANRHSQGSERDLSREVHKAEWRLKEQKLKDDIRGLR XP_004840084.1/1-1026 LLLISQELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWRLKEQKLKDDIRSLR ENSP00000378500/1-1046 LVLISQELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWRIKEQKLKDDIRGLR ENSMUSP00000098212/1-1047 LVHISQELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWRIKEQKLKDDIRGLR ENSRNOP00000035734/1-1047 LVHISQELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWRIKEQKLKDDIRGLR *: ************************** *.**************:**********.** ENSCPOP00000016467/1-1049 EKLMGLYKDKGL-EQRRHSLFDPAAAAPQEMLRLQRQLAGTEDALRAWLEQAQRVNRLSP XP_004840084.1/1-1026 EKLTGLDKDKAL-EQRRYSLIDP--AAAPELLRLQRQLAGTEDALRAALEQTQRVEALVE ENSP00000378500/1-1046 EKLTGLDKEKSLSDQRRYSLIDR--SSAPELLRLQHQLMSTEDALRDALDQAQQVEKLME ENSMUSP00000098212/1-1047 EKLTGLDKEKSLSEQRRYSLIDP--ASPPELLKLQHQLVSTEDALRDALNQAQQVERLVE ENSRNOP00000035734/1-1047 EKLTGLDKEKSLSEQKRYSLIDP--ASAPELLRLQHQLVSTEDALRDALDQAQQVERLVE *** ** *:*.* :*:*:**:* ::. *:*:**:** .****** *:*:*:*: * ENSCPOP00000016467/1-1049 FPLHLADR----GQLRLPQRIHQQDKAHKQEDKH XP_004840084.1/1-1026 ALRGAGAQ--TMGSSSSANGIHQQDKAHKQEDKH ENSP00000378500/1-1046 AMRSCPDKAQTIGNSGSANGIHQQDKAQKQEDKH ENSMUSP00000098212/1-1047 ALRGCSDRTQTISNSGSANGIHQPDKAHKQEDKH ENSRNOP00000035734/1-1047 ALRGCSDRTQTISNSGSANGIHQPDKAHKQEDKH : .. .: *** ***:******