CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000073618/1-1038 ------------------------------------------------------------ ENSRNOP00000028137/1-1040 ------------------------------------------------------------ ENSP00000436269/1-1042 ----------------------------------------------------------MP ENSCPOP00000016297/1-1100 WRRTRLGAWVPVFSSGPSEQPPPPSGQEPLPQPQPAGCSPNTCVCQCGPASREPGPQSVP XP_004852441.1/1-1070 ----------------------------------------------------------MP ENSMUSP00000073618/1-1038 MWAGGVGSPRRGMAPAPTDDLFARKLRQPARPPLTPHTFEPRPARGPLLRSGSDAGEVRP ENSRNOP00000028137/1-1040 MWAGGVGSPRRGMAPAPTDDLFARKLRQPARPPLTPHTFEPRPARGPLLRSGSDAGEVRP ENSP00000436269/1-1042 MWAGGVGSPRRGMAPASTDDLFARKLRQPARPPLTPHTFEPRPVRGPLLRSGSDAGEARP ENSCPOP00000016297/1-1100 MWAGGVGSPRRGMAPAPTDDLFARKLRQPARPPLTPHTFEPRPARSPLLRSGSDAGEARP XP_004852441.1/1-1070 MWTGGVGSPRQGTAPAPTDDLFARKLRQPARPPLTPHTFEPRPAWSPLLRSGSDAGEARP **:*******:* ***.**************************. .***********.** ENSMUSP00000073618/1-1038 PTPASPRARAHSHEDASRPAATPTRLFTDPLALLGLPAEEPEPTFPPVLEPRWFAHYDVQ ENSRNOP00000028137/1-1040 PTPASPRARAHSHEDTSRPAATPTRLFTDPLALLGLPAEEPEPTFPPVLEPRWFAHYDVQ ENSP00000436269/1-1042 PTPASPRARAHSHEEASRPAATSTRLFTDPLALLGLPAEEPEPAFPPVLEPRWFAHYDVQ ENSCPOP00000016297/1-1100 PTPASPRARAHSHEDASRPAAAPTRLFTDPLALLGLPAEEPEPTFPPVLEPRWFAHYDVQ XP_004852441.1/1-1070 PTPASPRARAHSHEDASRPAAVPTRLFTDPLALLGLPAEEPEPTYPPVLEPRWFAHYDVQ **************::*****..********************::*************** ENSMUSP00000073618/1-1038 SLLFDWAPRPRGTGSHIEANSGTL--AEGQTTTSDLLLGAPGFVSELGGEGELGLGGPIS ENSRNOP00000028137/1-1040 SLLFDWAPRPRATGSHTESNSGTLALAEDQTTTSDLLLGAPGFVSELGGEGELGLGGPIS ENSP00000436269/1-1042 SLLFDWAPRSQGMGSHSEASSGTLASAEDQAASSDLLHGAPGFVCELGGEGELGLGGPAS ENSCPOP00000016297/1-1100 SLLFDWAP-PRGTRGHTEASPATPTSAEDQAASSDLLLGAPGFVSELGGEGELGLGGPMS XP_004852441.1/1-1070 SLLFDWAPQPQGTRGHMEASSATPASAEDQSAISDLLLGAPGFVSELGGEGELGLGGPMS ******** .:. .* *:...* **.*:: **** ******.************* * ENSMUSP00000073618/1-1038 PPVPPALPNAAVSVLEEPQTRTTAYSLEHADLGAGYYRKYFYGKEHQNFFGLDEALGPVA ENSRNOP00000028137/1-1040 PPVPPALPNASVSVLEEPQTRTTAYSLEHADLGAGYYRKYFYGKEHQNFFGLDEALGPVA ENSP00000436269/1-1042 PPVPPALPNAAVSILEEPQNRTSAYSLEHADLGAGYYRKYFYGKEHQNFFGMDESLGPVA ENSCPOP00000016297/1-1100 PPVPPALPNAAVSILEEPQTRTAAYSLEHADLGAGYYRKYFYGKEHQNFFGVDEELGPVA XP_004852441.1/1-1070 PPVPPALPNAAVSILEEPQNRTTAYSLEHADLGAGYYRKYFYGKEHQNFFGVDEELGPVA **********:**:*****.**:****************************:** ***** ENSMUSP00000073618/1-1038 VSLRREEKEGSGGGTLHSYRVIVRTTQLRTLRGTISEDALPPGPPRGLSPRKLLEHVAPR ENSRNOP00000028137/1-1040 VSLRREEKEGSGGGTLHSYRVIVRTTQLRTLRGTISEDALPPGPPRGLSPRKLLEHVAPR ENSP00000436269/1-1042 VSLRREEKEGSGGGTLHSYRVIVRTTQLRTLRGTISEDALPPGPPRGLSPRKLLEHVAPQ ENSCPOP00000016297/1-1100 VSLQREEKEGSGGGTLHSYRVIVRTTQLRTLRGTISEDALPTGPTRGLSPRKLLEHVAPR XP_004852441.1/1-1070 VSLRREEKEGSGGSTLHSYRVIVRTTQLRTLRGTISEDALPPGPPRGLSPRKLLEHVAPR ***:*********.***************************.**.**************: ENSMUSP00000073618/1-1038 LSPTCLRLGSASPKVPRTLLTLDEQVLSFQRKVGILYCRAGQGSEEEMYNNQEAGAAFMQ ENSRNOP00000028137/1-1040 LSPTCLRLGSASPKVPRTLLTLDEQVLSFQRKVGILYCRAGQGSEEEMYNNQEAGAAFMQ ENSP00000436269/1-1042 LSPSCLRLGSASPKVPRTLLTLDEQVLSFQRKVGILYCRAGQGSEEEMYNNQEAGPAFMQ ENSCPOP00000016297/1-1100 LSPSCLRLGSASPKVPRTLLTLDEQVLSFQRKVGILYCRSGQGTEEEMYNNEEAGVAFTQ XP_004852441.1/1-1070 LSPSCLRLGSASPKVPRTLLTLDEQVLSFQRKVGILYCRTGQGSEEEMYNNQEAGMAFTQ ***:***********************************:***:*******:*** ** * ENSMUSP00000073618/1-1038 FLTLLGDVVRLKGFESYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQL ENSRNOP00000028137/1-1040 FLTLLGDVVRLKGFENYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQL ENSP00000436269/1-1042 FLTLLGDVVRLKGFESYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQL ENSCPOP00000016297/1-1100 FLTLLGDVVRLKGFDSYRAQLDTKTDSTGTHSLYTTYQDHEIMFHVSTMLPYTPNNQQQL XP_004852441.1/1-1070 FLTLLGDVVRLKGFDSYRAQLDTKTDSTGTHSLYTMYQDHEIMFHVSTMLPYTPNNQQQL **************:.******************* ************************ ENSMUSP00000073618/1-1038 LRKRHIGNDIVTIVFQEPGSKPFCPTTIRSHFQHVFLVVRAHAPCTPHTSYRVAVSRTQD ENSRNOP00000028137/1-1040 LRKRHIGNDIVTIVFQEPGSKPFCPTTIRSHFQHVFLVVRAHAPCTPHTSYRVAVSRTQD ENSP00000436269/1-1042 LRKRHIGNDIVTIVFQEPGSKPFCPTTIRSHFQHVFLVVRAHTPCTPHTTYRVAVSRTQD ENSCPOP00000016297/1-1100 LRKRHIGNDIVTIVFQEPGSKPFCPTTIRSHFQHIFIVVRAHAPCTPHTSYRVAVSRTQD XP_004852441.1/1-1070 LRKRHIGNDIVTIVFQEPGSKPFCPTTIRSHFQHVFIVVRAHAPCTPHASYRVAVSRTQD **********************************:*:*****:*****::********** ENSMUSP00000073618/1-1038 TPAFGPALPEGGGPFAANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDLATN ENSRNOP00000028137/1-1040 TPAFGPALPEGGGPFAANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDLATN ENSP00000436269/1-1042 TPAFGPALPAGGGPFAANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDLATN ENSCPOP00000016297/1-1100 TPAFGPALPPGGGPFAANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDLATN XP_004852441.1/1-1070 TPAFGPALPPGGGPFSANADFRAFLLAKALNGEQAAGHARQFHAMATRTRQQYLQDLATN ********* *****:******************************************** ENSMUSP00000073618/1-1038 EVTTTSLDSASRFGLPSLGGRRRATPRSPGAELQAAGALMWGVRAAPGARVAAGAETSGP ENSRNOP00000028137/1-1040 EVTTTSLDSASRFGLPSLGGRRRATPRSPGAELQAAGALMWGVRAAPGARVSAGAETGGP ENSP00000436269/1-1042 EVTTTSLDSASRFGLPSLGGRRRAAPRGPGAELQAAGSLVWGVRAAPGARVAAGAQASGP ENSCPOP00000016297/1-1100 EVTTTSLDSASRFGLPSLGGRRRATPRGPGCELQAAGALTWGVRAAPGTRVAAGAEAGGP XP_004852441.1/1-1070 EVTTTSLDSASRFGLPSLGGRRRATPRSPGCELQAAGALTWGVRAAPGARVAVGAEVGSP ************************:**.**.******:* ********:**:.**:...* ENSMUSP00000073618/1-1038 EDAEVPCLLGISAETLVLVAPRDGRVVFNCACRDVLAWTFSEHQLDLYHGRGEAITLRLD ENSRNOP00000028137/1-1040 DHAEVPCLLGISAETLVLVTPRDGRVVFNCACRDVLAWTFSDHQLDLYHGRGEAITLRLD ENSP00000436269/1-1042 EGIEVPCLLGISAEALVLVAPRDGRVVFNCACRDVLAWTFSEQQLDLYHGRGEAITLRFD ENSCPOP00000016297/1-1100 EGAEVPCLLGISAETLVLVAPRDGRVVFNCACRDVLAWTFSEQQLDLYHGRGEAITLRFD XP_004852441.1/1-1070 DSAELPCLLGISAEALVLVAPRDGRVVFNCACRDVLAWTFSEHQLDLYHSRGEAITLRFD : *:*********:****:*********************::******.********:* ENSMUSP00000073618/1-1038 GAPGQAVGEVVARLQLVSRGCETRELALPRDGQGRLGFEVDAEGFITHVERFTFAETTGL ENSRNOP00000028137/1-1040 GAPGQAVGEVVARLQLVSRGCETRELALPRDGQGRLGFEVDAEGFITHVERFTFAETTGL ENSP00000436269/1-1042 GSPGQAVGEVVARLQLVSRGCETRELALPRDGQGRLGFEVDAEGFVTHVERFTFAETAGL ENSCPOP00000016297/1-1100 GAPGQAVGEVVTRLQLVSRGCETRELAPPRDGQGRLGFEVDAEGFITDVERFTFAEKAGL XP_004852441.1/1-1070 GAPGQAVGEVVTRLQLVSRGCETRELAPPRDGQGRLGFEVDTEGFITHVERFTFAEKAGL *:*********:*************** *************:***:*.********.:** ENSMUSP00000073618/1-1038 RPGARLLRVCGQTLPKLGPEAAAQMLRSAPKVCVTVLPPDESGRPRRSFSELYMLSLKEP ENSRNOP00000028137/1-1040 RPGARLLRVCGQTLPKLGPEAAAQMLRSASKVCVTVLPPDESGRPRRSFSELYTLSLKEP ENSP00000436269/1-1042 RPGARLLRVCGQTLPSLRPEAAAQLLRSAPKVCVTVLPPDESGRPRRSFSELYTLSLQEP ENSCPOP00000016297/1-1100 RPGARLLRVCGRTLPSLGPEAAAQLLRLAPKVCITVLPPEESGRPRRSFSELYRRSLQEP XP_004852441.1/1-1070 RPGARLLRVCGRTLPSLGPEATAQLLRSAPKVCVTVLPPEESGRPRRSFSELYTLSLQEP ***********:***.* ***:**:** *.***:*****:************* **:** ENSMUSP00000073618/1-1038 SRRGGPEPVQDETGKLVILPPTKQLLHFCLKDSSSPPGPGDLTEERTEFLRSHNSL-SSG ENSRNOP00000028137/1-1040 SRRAAPEPEQDETEKLVTLPAAKQLLHFCLKDGGSPPGPGDLTEERTEFLHSHNSL-SPR ENSP00000436269/1-1042 SRRGAPDPVQDEVQGVTLLPTTKQLLHLCLQDGGSPPGPGDLAEERTEFLHSQNSL-SPR ENSCPOP00000016297/1-1100 SRRGPPEPVQDETQEVVLQPITRQLLRLCLQDGASPPGPGDLAEERTEFLHSQNSLPSPH XP_004852441.1/1-1070 SRRVAPEPAQDETLEVVLQPIAKQLLRLCLQDGGGPPGPGDLAEERTEFLHSQNSP-SPR *** *:* ***. :. * ::***::**:*...*******:*******:*:** *. ENSMUSP00000073618/1-1038 SSLSDEAPVLPNTTPDLLLVTTANPSAPGTDRETPPSQDQSGSPSSHEDTSDSGPELRAS ENSRNOP00000028137/1-1040 SSMSDEAPVLPNTTPDLLLVTAVTTLAPGTDRETPPSQDQSGSSSSHEDTSDSAPELRAS ENSP00000436269/1-1042 SSLSDEAPVLPNTTPDLLLATTAKPSVPSADSETPLTQDRPGSPSGSEDKGNPAPELRAS ENSCPOP00000016297/1-1100 SSLSDEAPVLPNTTPDLLLAATAKPAAPGAGRETPSSQERPGSPSDHKDKGNLAPELRAS XP_004852441.1/1-1070 SSLSDEAPVLPNTTPDLLLVTTAKPAVPGAGRETPPSQEQPGSPSGHEDRDNLAPELKAS **:****************.::... .*.:. *** :*::.**.*. :* .: .***:** ENSMUSP00000073618/1-1038 ILPRTLSLRNSISKIMSEAGSETLEDEWQSISEIASTCNTILESLSREGQPISESGDPKE ENSRNOP00000028137/1-1040 ILPRTLSLRNSISKIMSEAGSETLEDEWQSISEIASTCNTILESLSREGQPILESGDPKE ENSP00000436269/1-1042 FLPRTLSLRNSISRIMSEAGSGTLEDEWQAISEIASTCNTILESLSREGQPIPESGDPKG ENSCPOP00000016297/1-1100 FLPRTLSLRNSISKIMSEAGSDTLEDEWQSISEIASTCNTILESLSREGQPIPESGDPKG XP_004852441.1/1-1070 FLPRTLSLRNSISKIMSEAGSETLEDEWQSISEIASTCNTILESLSREGQSIPESGDPKG :************:******* *******:********************.* ****** ENSMUSP00000073618/1-1038 ALKCDSEPEPGSLSEKVSHLESMLWKLQEDLQR--------------------------- ENSRNOP00000028137/1-1040 TSKCNSEPEPGSLSEKVSHLESMLRKLQEDLQR--------------------------- ENSP00000436269/1-1042 TPKSDAEPEPGNLSEKVSHLESMLRKLQEDLQK--------------------------- ENSCPOP00000016297/1-1100 TPKSDAEPEPGSLSEKVSHLEAMLRKLQEDLKK--------------------------- XP_004852441.1/1-1070 TPKSDAEPEPRSLSEKVSHLEAMLRKLQEDLKKVRRWSGACGESRGCSRKGVAGDCCPPP : *.::**** .*********:** ******:: ENSMUSP00000073618/1-1038 -EKADRAALEEEVRSLRHNNQRLLAESESAATRLLLASKHLGAPTTDLA ENSRNOP00000028137/1-1040 -EKADRAALEEEVRSLRHNNQRLLAESESAATRLLLASKQLGSPTTDLA ENSP00000436269/1-1042 -EKADRAALEEEVRSLRHNNRRLQAESESAATRLLLASKQLGSPTADLA ENSCPOP00000016297/1-1100 -EKADKAALEEEVRSLRHNNQRLLAESESAATRLLLASKQLGSAATDLA XP_004852441.1/1-1070 QEKADRAALEEEVRSLRHNNQRLLAESESAATRLLLASKQLGSPTTDLA ****:**************:** ***************:**:.::***