CLUSTAL W(1.81) multiple sequence alignment ENSP00000272847/1-550 ------------------------------------------------------------ ENSMUSP00000027083/1-546 ------------------------------------------------------------ ENSRNOP00000021099/1-546 ------------------------------------------------------------ ENSCPOP00000015615/1-521 ------------------------------------------------------------ XP_004851394.1/1-700 MGQRHTLPSTPPGRRVHAYGTGAMVRRKSVLEGWGLLRTAADARPSRSPKPVSSRAPPAR ENSP00000272847/1-550 ------------------------------------------------------------ ENSMUSP00000027083/1-546 ------------------------------------------------------------ ENSRNOP00000021099/1-546 ------------------------------------------------------------ ENSCPOP00000015615/1-521 ------------------------------------------------------------ XP_004851394.1/1-700 RGLVDPPRGPTALGTEKGGAEAVSVEVAAAAGAPGATPASVGRRGHPLASPPGIGRPRIP ENSP00000272847/1-550 ----------------------------------MAGLGASLHVWGWLMLGSCLLARAQL ENSMUSP00000027083/1-546 ----------------------------------MAWLETFTYICGWLILSSCLLVRAQL ENSRNOP00000021099/1-546 ----------------------------------MPWLEALPYICGWLILRSCLLVGAQL ENSCPOP00000015615/1-521 ----------------------------------------------------------QL XP_004851394.1/1-700 QPRRSGARAPRKFVPRRPRWPLKGSSLLPPAVSGMARLGASPYVWGWLVLLSCLLAGAQL ** ENSP00000272847/1-550 DSDGTITIEEQIVLVLKAKVQCELNITAQLQ-EGEGNCFPEWDGLICWPRGTVGKISAVP ENSMUSP00000027083/1-546 DSDGTITIEEQIVLVMKAKMQCELNITAQLQ-EGEGNCFPEWDGIICWPRGTVGKMSAVP ENSRNOP00000021099/1-546 DSDGTITIEEQIVLVMKAKMQCELNITAQFQ-EGEGNCFPEWDGLICWPRGTAGKTSAMP ENSCPOP00000015615/1-521 DSDGVVTIEEQIVLIMKAKVQCERNITAQPQEEAEGSCFPEWDGLICWPR-TLGKILAVP XP_004851394.1/1-700 DSDGIVTIEEQIVLVMKAKMQCEQNITAQLQ-EGEGNCFPEWDGLICWPRGAAGKILAVP **** :********::***:*** ***** * *.**.*******:***** : ** *:* ENSP00000272847/1-550 CPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLY ENSMUSP00000027083/1-546 CPPYVYDFNHKGVAFRHCTPNGTWDSIHGSNKTWANYSDC--FLQPDINIGKQEFFESLY ENSRNOP00000021099/1-546 CPSYVYDFNHKGVAFRHCTPNGTWDFIHGSNKTWANYSDC--FLQPDINIGKQEFFENLY ENSCPOP00000015615/1-521 CPPYIYDFNHKGVAFRHCTDNGTWGVIHSSNKTWANYSDC--FLQPDISTGKQEFFESLY XP_004851394.1/1-700 CPAYIYDFNHKGVAFRHCTLNGTWDFIQSSNKTWANYSDC--FLQPDISIGKQEFFESLY **.*:*************. ****. ::. ********** ******. ******* ** ENSP00000272847/1-550 VMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHI ENSMUSP00000027083/1-546 ILYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHLHLFVSFMLRAMSIFVKDRVAQAHL ENSRNOP00000021099/1-546 ILYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHLHLFVSFMLRAMSIFVKDRVAQAHL ENSCPOP00000015615/1-521 TLYTIGYSISFGSLTVAILIIGYFRRLHCTRNYIHLHLFMSFMLRAISIFVKDKAAQAHL XP_004851394.1/1-700 ILYTIGYSISFGSLAVAILIIGYFRRLHCTRNYIHLHLFVSFMMRAISIFVKDKVAHAHL :**:*********:********************:***:***:** ******:..:**: ENSP00000272847/1-550 GVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLI ENSMUSP00000027083/1-546 GVEALQSLVMQGDLQNFIGGPSVDKSQYVGCKIAVVMFIYFLATNYYWILVEGLYLHNLI ENSRNOP00000021099/1-546 GVEALQSLVMQGDLQNFIGGPSVDKSQYVGCKIAVVMFIYFLATNYYWILVEGLYLHNLI ENSCPOP00000015615/1-521 RIGELQSLMVQDDLQNSIGVPSLDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLI XP_004851394.1/1-700 RIGELQSLML-NDLQNSIGVPSVDKSQYIGCKIAVVLFIYFLATNYYWILVEGLYLHNLI : *:**:: .* ** * .*:*****:*******:*********************** ENSP00000272847/1-550 FVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWELSAGDIKWIYQAPILAA ENSMUSP00000027083/1-546 FVSFFSDTKYLWGFISIGWGFPAVFVVAWAVARATLADTRCWELSAGD-RWIYQAPILAA ENSRNOP00000021099/1-546 FVSFFSDTKYLWGFILIGWGFPAVFVVAWAVARATLADTRCWELSAGD-RWIYQAPILAA ENSCPOP00000015615/1-521 FVSFFSDTKYLWGFIWIGWGFPAVFVVAWAVARATLADTRCWELSAGD-RWIYQAPILAA XP_004851394.1/1-700 FVSFFSDSKYLWGFICIGWGFPAAFVVAWAVARATLADTRCWELSAGD-KWIYQAPILAA **:****:******* *******.**.***********:********* :********** ENSP00000272847/1-550 IGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHS ENSMUSP00000027083/1-546 IGLNFILFLNTVRVLATKIWETNAVGHDMRKQYRKLAKSTLVLVLVFGVHYIVFVCQPHS ENSRNOP00000021099/1-546 IGLNFILFLNTVRVLATKIWETNAVGHDMRKQYRKLAKSTLVLVLVFGVHYIVFICQPHS ENSCPOP00000015615/1-521 IGLNFILFLNTVRVLATKIWETNAVGHNMRKQYRKLAKSTLVLVLVFGVHYIVFICQPHS XP_004851394.1/1-700 IGLNFVLFLNTVRVLATKIWETNAVGHDMRKQYRKLSKSTLVLVLVFGVHYIVFICQPHS *****:*********************: *******:*****************:* *** ENSP00000272847/1-550 FTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNLSVDWKRTPPCGS ENSMUSP00000027083/1-546 FSGLWWEIRMHCELFFNSFQGFFVSIVYCYCNGEVQAEVKKMWTRWNLSIDWKRAPPCGG ENSRNOP00000021099/1-546 FSGLWWEIRMHCELFFNSFQGFFVSIVYCYCNGEVQAEVKKTWTRWNLSIDWKKAPPCGG ENSCPOP00000015615/1-521 FTGLWWEIRMHCELFFNSFQGFFVSIVYCYCNGEVQAEVKKTWSRWNLSIDWKRTAPCGS XP_004851394.1/1-700 FTGLWWEIRMHCELFFNSFQGFFVSIVYCYCNGEVQAEVKKMWNRWNLSIDWQRPPPCGN *:** *********************:************** *.*****:**::..***. ENSP00000272847/1-550 RRCGSVLTTVTHSTSSQSQVAASTRMVLISGKAAKIASRQPDSHITLPGYVWSNSEQDCL ENSMUSP00000027083/1-546 QRYGSVLTTVTHSTSSQSQMGASTRLVLISGKPTKNACRQIDSHVTLPGYVWSSSEQDCQ ENSRNOP00000021099/1-546 HRYGSVLTTVTHSTSSQSQMGPSTRLVLISSKPAKTACRQIDSHVTLPGYVWSSSEQDCQ ENSCPOP00000015615/1-521 HRYGSVLTTVTHSTSSQSHMAASTRMVLLSGKPAKTSRRPPDSHVTLPGYVWSNSEQDCM XP_004851394.1/1-700 HRYGSVLTTVTHSTSSQSQMAASTRMVLISGKPAKTANRLPDCHVTLPGYVWSNSEQDCL :* ***************::..***:**:*.*.:* : * *.*:********.***** ENSP00000272847/1-550 PHSFHEETKEDSGRQGDDILMEKPSRPMESNPDTEGCQGETEDVL ENSMUSP00000027083/1-546 THSPPEETKEGHRRQGDDSPVMESSRPVAFTLDTEGCKGETHPI- ENSRNOP00000021099/1-546 PQSTPEETKKGHGRQEDDSPVGESSRPVAFTIDTEGCKGESHPI- ENSCPOP00000015615/1-521 PDSIHEETKEGSRRQGDDIPGEQSSRPLDFTL--EGCRGETEDVI XP_004851394.1/1-700 PHSIHEETKEGSRRKGDAIPVEGSSRPLEFTLDTERCKGETEDVI ..* ****:. *: * .***: . * *:**:. :