CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000015501/1-719 ------------------------------------------------------------ ENSP00000288602/1-766 MAALSGG-------------------GGGGAEPGQALFNGDMEPEAGAGAGAAASSAADP XP_004851344.1/1-762 MAALS---------------------GGGGAEQGQALFNGDMELE--AGAGAAASSVADP ENSMUSP00000002487/1-804 MAALSGGGGSSSGGGGGGGGGGGGGDGGGGAEQGQALFNGDMEPE--AGAGAAASSAADP ENSRNOP00000014604/1-803 MAALSGGGGSSSGGGGGGGGGGGGG-GGGGAEQGQALFNGDMEPE--AGAGAAASSAADP ENSCPOP00000015501/1-719 -----VWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLE ENSP00000288602/1-766 AIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLE XP_004851344.1/1-762 AIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLE ENSMUSP00000002487/1-804 AIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLE ENSRNOP00000014604/1-803 AIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLE ******************************************************* ENSCPOP00000015501/1-719 SLGNGTDFSVSSSASLDTVTSSSSSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFL ENSP00000288602/1-766 SLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFL XP_004851344.1/1-762 SLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFL ENSMUSP00000002487/1-804 SL---------------------------------VFQTPTDASRNNPKSPQKPIVRVFL ENSRNOP00000014604/1-803 SL---------------------------------VFQTPTDVSRNNPKSPQKPIVRVFL ** ***.***.:*.************** ENSCPOP00000015501/1-719 PNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEE ENSP00000288602/1-766 PNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEE XP_004851344.1/1-762 PNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEE ENSMUSP00000002487/1-804 PNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEE ENSRNOP00000014604/1-803 PNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEE ************************************************************ ENSCPOP00000015501/1-719 LHVEVLENVPLTTHNFVNRLVFQLNMCDESRVLVFKSISCFMLSFKFHIDVNEESPLQCF ENSP00000288602/1-766 LHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCV XP_004851344.1/1-762 LHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCV ENSMUSP00000002487/1-804 LHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCV ENSRNOP00000014604/1-803 LHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCV *****************.: .* * :** .* *:*:.: * .:*** . * ** *. ENSCPOP00000015501/1-719 NHEPHSLLFVSKFFEHHPIPQEEASLAETTLTSGSSPSAPPSESIGPPILTSPSPSKSIP ENSP00000288602/1-766 NYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIP XP_004851344.1/1-762 NYDQLDLLFVSKFFEHHPIPQEEASLAETTLTSGSSPSAPPSESIGPSILTSPSPSKSIP ENSMUSP00000002487/1-804 NYDQLDLLFVSKFFEHHPVPQEEASFPETALPSGSS-SAPPSDSTGPQILTSPSPSKSIP ENSRNOP00000014604/1-803 NYDQLDLLFVSKFFEHHPVPQEEAFSAETTLPSGCS-SAPPSDSIGPQILTSPSPSKSIP *:: .************:***** .**:*.**.* ***.*:* ** ************ ENSCPOP00000015501/1-719 IPQPFRPGEEDHRNQFGQRDRSSSAPNVHINTIEPVNID------------DLIRDQGFR ENSP00000288602/1-766 IPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNID------------DLIRDQGFR XP_004851344.1/1-762 IPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNID------------DLIRDQGFR ENSMUSP00000002487/1-804 IPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDEKFPEVELQDQRDLIRDQGFR ENSRNOP00000014604/1-803 IPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDEKFPEVELQDQRDLIRDQGFR *******.:****************************** ********* ENSCPOP00000015501/1-719 SDG----------------------------------------GSTTGLSATPPASLPGS ENSP00000288602/1-766 GDG----------------------------------------GSTTGLSATPPASLPGS XP_004851344.1/1-762 SDG----------------------------------------GSTTGLSATPPASLPGS ENSMUSP00000002487/1-804 GDGAPLNQLMRCLRKYQSRTPSPLLHSVPSEIVFDFEPGPVFRGSTTGLSATPPASLPGS ENSRNOP00000014604/1-803 GDGAPLNQLMRCLRKYQSRTPSPLLHSVPSEIVFDFEPGPVFRGSTTGLSATPPASLPGS .** ***************** ENSCPOP00000015501/1-719 LTNVKALQKSPGPQRERKSSSSS---EDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSG ENSP00000288602/1-766 LTNVKALQKSPGPQRERKSSSSS---EDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSG XP_004851344.1/1-762 LTNVKALQKSPGPQRERKSSSSS---EDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSG ENSMUSP00000002487/1-804 LTNVKALQKSPGPQRERKSSSSSSS-EDRSRMKTLGRRDSSDDWEIPDGQITVGQRIGSG ENSRNOP00000014604/1-803 LTNVKALQKSPGPQRERKSSSSSSSTEDRSRMKTLGRRDSSDDWEIPDGQITVGQRIGSG *********************** ***.****************************** ENSCPOP00000015501/1-719 SFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLA ENSP00000288602/1-766 SFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLA XP_004851344.1/1-762 SFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLA ENSMUSP00000002487/1-804 SFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLA ENSRNOP00000014604/1-803 SFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLA ************************************************************ ENSCPOP00000015501/1-719 IVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE ENSP00000288602/1-766 IVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE XP_004851344.1/1-762 IVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE ENSMUSP00000002487/1-804 IVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE ENSRNOP00000014604/1-803 IVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHE ************************************************************ ENSCPOP00000015501/1-719 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMRDKNPYSFQSDVYAFGIVL ENSP00000288602/1-766 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL XP_004851344.1/1-762 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL ENSMUSP00000002487/1-804 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL ENSRNOP00000014604/1-803 DLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVL *****************************************:****************** ENSCPOP00000015501/1-719 YE-MTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPL ENSP00000288602/1-766 YELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPL XP_004851344.1/1-762 YELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPL ENSMUSP00000002487/1-804 YELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPL ENSRNOP00000014604/1-803 YELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPL ** ********************************************************* ENSCPOP00000015501/1-719 FPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH ENSP00000288602/1-766 FPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH XP_004851344.1/1-762 FPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH ENSMUSP00000002487/1-804 FPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGEFAAF ENSRNOP00000014604/1-803 FPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGGFPVH ******************************************************* *... ENSCPOP00000015501/1-719 - ENSP00000288602/1-766 - XP_004851344.1/1-762 - ENSMUSP00000002487/1-804 K ENSRNOP00000014604/1-803 -