CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000015385/1-947 ------------------------------------------------------------ XP_004847392.1/1-987 ------------------------------------------------------------ ENSP00000422185/1-1159 MAHRGPSRASKGPGPTARAPSPGAPPPPRSPRSRPLLLLLL-LLGACGAAGRSPEPGRLG ENSMUSP00000041828/1-1159 MAHRGPPSAPKRPGPTAPDRSFQALLPPCWPRSWPLLLLLLVLVAACGAMGRSPQPGRQG ENSRNOP00000009960/1-987 ------------------------------------------------------------ ENSCPOP00000015385/1-947 ------------------------------------------------------------ XP_004847392.1/1-987 ------------------------------------------------------------ ENSP00000422185/1-1159 PHAQLTRVPRSPPAGRAEPGGGEDRQARGTEPGAPGPSPGPAPGPGEDGAPAAGYRRWER ENSMUSP00000041828/1-1159 PGVQITRL---LPAGRTESGDRKDPQARESEPSVPGLGPGSASGPSTDGAPAPGKGRRAR ENSRNOP00000009960/1-987 ------------------------------------------------------------ ENSCPOP00000015385/1-947 ------------------------------------------------------------ XP_004847392.1/1-987 -------------------------------------------------------MGKVL ENSP00000422185/1-1159 AAPLAGV--ASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVL ENSMUSP00000041828/1-1159 AVPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVL ENSRNOP00000009960/1-987 -------------------------------------------------------MGKVL ENSCPOP00000015385/1-947 --------------------------------------QIILVSSSLSDREQSLFLSTDE XP_004847392.1/1-987 ESSLWRSSDFGTSYTKLTLQPGVTTIIDNFYICPTNKRKIILVSSSLSDREQNLFLSTDE ENSP00000422185/1-1159 ESSLWRSSDFGTSYTKLTLQPGVTTVIDNFYICPTNKRKVILVSSSLSDRDQSLFLSADE ENSMUSP00000041828/1-1159 ESSLWRSSDFGTTYTKLTLQPGVTTVIDNFYICPANKRKIILVSSSLGDREQSLFLSTDE ENSRNOP00000009960/1-987 ESSLWRSSDFGTTYTKLTLQPGVTTVIDNFYICPANKRKIILVSSSLGDREQSLFLSTDE ::*******.**:*.****:** ENSCPOP00000015385/1-947 GASFQRQPIPFLAETLLFHPKDEDKVLAYTKESKLYVSSDLGKKWTLLQEQVTKDHVFWA XP_004847392.1/1-987 GTSFQRQPITFLVETLLFHPRDEDKVLAYTKESKLYVSLDLGKKWTLLQEQVTKDHVFWA ENSP00000422185/1-1159 GATFQKQPIPFFVETLIFHPKEEDKVLAYTKESKLYVSSDLGKKWTLLQERVTKDHVFWS ENSMUSP00000041828/1-1159 GATFQKYPVPFLVEMLLFHPKEEDKVLAYTKDSKLYVSSDLGKKWTLLQERVTKDHVFWA ENSRNOP00000009960/1-987 GTTFQKYPVPFLVETLLFHPKEEDKVLAYTKDSKLYVSSDLGKKWTLLQEQVTKDHVFWA *::**: *:.*:.* *:***::*********:****** ***********:********: ENSCPOP00000015385/1-947 VSGVDADPDLVHMETQDLGGAFRYVTCQIHNCSDKVLAAPFPWPIDRGSLTVQDDYIFLK XP_004847392.1/1-987 VSGVDADPNLVHMETQDLSGGFRYVTCQIHSCSDEMLAAPFPGPIDHGSLAVQDDYVLLK ENSP00000422185/1-1159 VSGVDADPDLVHVEAQDLGGDFRYVTCAIHNCSEKMLTAPFAGPIDHGSLTVQDDYIFFK ENSMUSP00000041828/1-1159 VSGVDDDPNLVHVEAQDLSGGYRYYTCLIYNCSAQPHIAPFSGPIDRGSLTVQDEYIFLK ENSRNOP00000009960/1-987 VSGVDDDPNLVHMEARDLSGGYRYYTCLIHNCSAQPHTAPFPGPTDRGSLTVQDEYIFLK ***** **:***:*::**.* :** ** *:.** : ***. * *:***:***:*:::* ENSCPOP00000015385/1-947 TTSANRTKYYVSCRRNGFALMKLPKHALPKKRPEGVISTDENQVFVAVIVRTVLGDTLHL XP_004847392.1/1-987 TTSTNQTKYYVSYRRNEFVLMKLPKYALPKDLQ--VISTDESQVFVAVQEWYQT-DTYNL ENSP00000422185/1-1159 ATSANQTKYYVSYRRNEFVLMKLPKYALPKDLQ--IISTDESQVFVAVQEWYQM-DTYNL ENSMUSP00000041828/1-1159 ATSTNRTKYYVSYRRSDFVLMKLPKYALPKDLQ--IISTDEQQVFVAVQEWNQV-DTYNL ENSRNOP00000009960/1-987 ATSTNRTKYYVSYRRSDFVLMKLPKYALPKDLQ--IISTDEQQVFVAVQEWNQV-DTYNL :**:*:****** **. *.******:****. :*****.****** ** :* ENSCPOP00000015385/1-947 HCTSKAQVALISIKAIVASTFEKQEHVVYTLSQVRGVKGVFLANRKVDGKVMTLITYNKG XP_004847392.1/1-987 YQSDPRGVRYALVLEDVRSSRQAEESVLIDILEVRGVKGVFLANRKVDGKVMTLITYNKG ENSP00000422185/1-1159 YQSDPRGVRYALVLQDVRSSRQAEESVLIDILEVRGVKGVFLANQKIDGKVMTLITYNKG ENSMUSP00000041828/1-1159 YQSDLRGVRYSLVLENVRSSRQAEENVVIDILEVRGVKGVFLANQKVDGKVTTVITYNKG ENSRNOP00000009960/1-987 YQSDLRGVRYSLVLENVRSSRQAEENVVIDILEVRGVKGVFLANQKVDGKVTTVITYNKG : :. * : * *: : :* *: : :***********:*:**** *:****** ENSCPOP00000015385/1-947 RDWDFLRPPSSDMNGKPTNCQPPACHLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLG XP_004847392.1/1-987 RDWDFLRPPSSDMNGKPTNCQPPDCHLHLHLRWADNPYVSGTVHTKDTTPGLIMGAGNLG ENSP00000422185/1-1159 RDWDYLRPPSMDMNGKPTNCKPPDCHLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLG ENSMUSP00000041828/1-1159 RDWDYLRPPSTDMNGKPTNCQPPDCYLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLG ENSRNOP00000009960/1-987 RDWDYLRPPSTDMNGKPTNCQPPDCHLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLG ****:***** *********:** *:**********************:*********** ENSCPOP00000015385/1-947 SQLVEYKEEMYVTADCGHTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSVDEGV XP_004847392.1/1-987 SQLVEYKEEMYITADCGRTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSVDGGV ENSP00000422185/1-1159 SQLVEYKEEMYITSDCGHTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSVDEGL ENSMUSP00000041828/1-1159 SQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDTSIPLKILKFSVDEGH ENSRNOP00000009960/1-987 SQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDTSIPLKTLKFSVDEGH ***********:*:***:***********:*********.********** ****** * ENSCPOP00000015385/1-947 TWSTHNFTGTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFSRLCSEDDY XP_004847392.1/1-987 TWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFSRPCGENDY ENSP00000422185/1-1159 TWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFSRQCGEEDY ENSMUSP00000041828/1-1159 TWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFPRQCGEDDY ENSRNOP00000009960/1-987 TWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFPRPCVEDDY ********.******************************************.* * *:** ENSCPOP00000015385/1-947 GSWDLASLQGDRCIMGQQRSFRKRKRESWCIQGRAFTSALMARVCQCRDSDFLCDDYGFE XP_004847392.1/1-987 SSWDLTSLQGDRCIMGQQRSFRKRKPASWCVQGRSFTSALTARVCQCRDSDFLC-DYGFE ENSP00000422185/1-1159 SSWELSNLQGDRCIMGQQRSFRKRKSTSWCIKGRSFTSALTSRVCECRDSDFLC-DYGFE ENSMUSP00000041828/1-1159 SSWDLTDLQGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRVCKCRDSDFLC-DYGFE ENSRNOP00000009960/1-987 SSWDLTDLQGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRVCKCRDSDFLC-DYGFE .**:*:.****:********:**** ***::**:***** :***:******** ***** ENSCPOP00000015385/1-947 RMASSEPGT-QCAANFWFNPLSPPDDCAVGQTYTSSLGYRKVVSNVCEGGVDLRRGPGPL XP_004847392.1/1-987 RTPSLEPGT-KCVANFWFNPLAPPDDCAVGQTYTSSLGYRKVVSNVCEGGVDLWRGPGPL ENSP00000422185/1-1159 RSSSSESSTNKCSANFWFNPLSPPDDCALGQTYTSSLGYRKVVSNVCEGGVDMQQSQVQL ENSMUSP00000041828/1-1159 RSSSSESTANKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQL ENSRNOP00000009960/1-987 RSSSSESTVNKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQL * .* *. . :* ********:**:**.:***********************: :. * ENSCPOP00000015385/1-947 QCPLMPPRGLRVSILGEAVAVQPGEDVLFVVQQERGDILTTKYQVDLGDGFRAMYVNLTM XP_004847392.1/1-987 QCPLTRPRGLRVSILGEAVAVRPGEDVLFVVRQEQGDILTTKYQVDLGDGFKAMYVNLTL ENSP00000422185/1-1159 QCPLTPPRGLQVSIQGEAVAVRPGEDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTL ENSMUSP00000041828/1-1159 QCPLQAPRGLQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTL ENSRNOP00000009960/1-987 QCPLQAPRGLQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTL **** ****:*** ******:* *******:**:**:*************:*******: ENSCPOP00000015385/1-947 TGEPIRHRYESPGVYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVAPVIGINQDVNLT XP_004847392.1/1-987 TAEPIRHRYESPGVYRVSVRAENVAGHDEAVLFVQVNSPLQALYLEVAPVVGINQDMNLT ENSP00000422185/1-1159 TGEPIRHRYESPGIYRVSVRAENTAGHDEAVLFVQVNSPLQALYLEVVPVIGLNQEVNLT ENSMUSP00000041828/1-1159 TGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGVNQEVNLT ENSRNOP00000009960/1-987 TGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGINQEVNLT *.*****:*****:********* ***********************.**:*:**::*** ENSCPOP00000015385/1-947 AVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFVAPGDVRVTVQAACGSSVLQDSKVV XP_004847392.1/1-987 AVLLPPNPNLTVFYWWIGHSLQPLLSLDNSVTTRFAAPGDVRVSVQAACGSSVLQDSRVV ENSP00000422185/1-1159 AVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFSDTGDVRVTVQAACGNSVLQDSRVL ENSMUSP00000041828/1-1159 AVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTKFTDAGDVRVTVQAACGNSVLQDSRLV ENSRNOP00000009960/1-987 AVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFTDAGDVRVTVQAACGNSVLQDSRLV ***** ***************************:* .*****:******.******::: ENSCPOP00000015385/1-947 RVLDQFQVVPLCFSQELDTFNPNTPEWREDVGLVVTRLLSKETNIPEELLVTVVKPGLPT XP_004847392.1/1-987 RVLDQFQLVPLCFSRELDALNPNTPEWREDVGLVVTRLLSKETSVPEELLVTVVRPGLPT ENSP00000422185/1-1159 RVLDQFQVMPLQFSKELDAYNPNTPEWREDVGLVVTRLLSKETSVPQELLVTVVKPGLPT ENSMUSP00000041828/1-1159 RVLDQFQVVPLRFSRELDTFNPNTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPT ENSRNOP00000009960/1-987 RVLDQFQVVPLQFSRDLDTFNPNTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPT *******::** **::**: ***********************.:*:*******:***** ENSCPOP00000015385/1-947 VADLYVLLPPPRPTRKRSLWSDKRLTAIRQALNAQKISFLLQGGLRVQVALRDTDTGSQS XP_004847392.1/1-987 VADLYVLLPPPRPTRKRSLSSDKRLTAVRQVLSAQKISFLLQGGLRVLVALRDTDTESQR ENSP00000422185/1-1159 LADLYVLLPPPRPTRKRSLSSDKRLAAIQQVLNAQKISFLLRGGVRVLVALRDTGTGAEQ ENSMUSP00000041828/1-1159 IADLYVLLPLPRPTRKRSLTSDKRLAAVQQALNSHRISFILRGGLRILVELRDTDTGPQR ENSRNOP00000009960/1-987 IADLYVLLPPPRPTRKRSLTSDKRLAAVQQALNSHRISFILRGGLRVLVELRDTDAGPQR :******** ********* *****:*::*.*.:::***:*:**:*: * ****.: .: ENSCPOP00000015385/1-947 LGGGGGYWAVVVLFVVGLFAVGAIILYKFKRKRPGRTVYAQMHNEKEQEMTSPVSHGEDA XP_004847392.1/1-987 LGGGSGYWAVVVLFVVGVFAVGAIVLYKFKRKRPGRTVYAQMHNEKEQEMTSPVSRSEDA ENSP00000422185/1-1159 LGGGGGYWAVVVLFVIGLFAAGAFILYKFKRKRPGRTVYAQMHNEKEQEMTSPVSHSEDV ENSMUSP00000041828/1-1159 PGGSGGYWAVVVLFVIGLFAVGAFILYKFKRKRPGRTVYAQMHNEKEQEMTSPVSHSEDA ENSRNOP00000009960/1-987 PGGSGGYWAVVVLFVIGLFAVGAFILYKFKRKRPGRTVYAQMHNEKEQEMTSPVSHSEDA **..**********:*:**.**::******************************:.**. ENSCPOP00000015385/1-947 QA-TVQGNHSGVVLSINSREMHSYLVS XP_004847392.1/1-987 QGTAMQGNHSGVVLSINSREMHGYLVS ENSP00000422185/1-1159 QG-AVQGNHSGVVLSINSREMHSYLVS ENSMUSP00000041828/1-1159 QS-TMQGNHSGVVLSINSREMHSYLVG ENSRNOP00000009960/1-987 QS-AMQGNHSGVVLSINSREMHSYLVG *. ::*****************.***.