CLUSTAL W(1.81) multiple sequence alignment ENSP00000438689/1-678 MLGGLAAAAGTRIMGKEIEAEAQRPLRQTWRPGQPPAMTAKTMSSRLTALLGQPRPGPAR ENSMUSP00000099634/1-656 ----MQSARMTPSVGRQL-------LRLGARSSRSTTV-----------LQGQPRPISAQ ENSRNOP00000024973/1-655 ----MQSARMTPSVGRQL-------LRLGARSSRSAA------------LQGQPRPTSAQ ENSCPOP00000014862/1-654 ----MQTAW-TPSVGRQL-------LRLGGRRSQPSP------------AFRQARPGPAL XP_004857422.1/1-655 ----MQTAWMTPSVGRQL-------LRLGSRRSQPSA------------VFGQPRPGLAL : :* * :*::: ** * .:... *.** * ENSP00000438689/1-678 RPYAGGAAQLALDKSDSHPSDALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEE ENSMUSP00000099634/1-656 RLYAREATQAVLDKPETLSSDASTREKPARAESKSFAVGMFKGQLTIDQVFPYPSVLSEE ENSRNOP00000024973/1-655 RLYASEATQAVLEKPETLSSDASTREKPARAESKSFAVGMFKGQLTTDQVFPYPSVLNEE ENSCPOP00000014862/1-654 RPYASSSTQVRGSGQIGFSPDASTRAKPTKAESKSFAVGMFKGQLITDQVFPYPSVLNEE XP_004857422.1/1-655 RPCASGTTQVIPDKSDSLSSDASTGAKPANAESKSFAVGMFKGQLTTDQVFPYPSVLNEE * * ::* . ..** * **:.*************** **********.** ENSP00000438689/1-678 QTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCN ENSMUSP00000099634/1-656 QAQFLKELVGPVARFFEEVNDPAKNDALEKVEDDTLQGLKELGAFGLQVPSELGGLGLSN ENSRNOP00000024973/1-655 QTQFLKELVGPVARFFEEVNDPAKNDSLEKVEEDTLQGLKELGAFGLQVPSELGGLGLSN ENSCPOP00000014862/1-654 QTQFLRELVGPVARFFEEVNDPAKNDTLERLEETTLQGLKDLGAFGLQVPSELGGVGLGN XP_004857422.1/1-655 QTQFLKELVGPVARFFEEVNDPAKNDTLECVEETTLQGLKELGAFGLQVPSELGGVGLCN *:***:*** **:*************:** :*: * ****:**************:** * ENSP00000438689/1-678 TQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLT ENSMUSP00000099634/1-656 TQYARLAEIVGMHDLGVSVTLGAHQSIGFKGILLYGTKAQREKYLPRVASGQALAAFCLT ENSRNOP00000024973/1-655 TQYARLAEIVGMHDLGVSVTLGAHQSIGFKGILLYGTKAQKEKYLPRVASGQALAAFCLT ENSCPOP00000014862/1-654 TQYARLAEIVGMHDLGVSVTLGAHQSIGFKGILLFGTKAQKEKYLPKVASGEALAAFCLT XP_004857422.1/1-655 TQYARLAEIVGMHDLGVSVTLGAHQSIGFKGILLFGTKAQKEKYLPKVASGEALAAFCLT ******.**********.:***************:*****:*****::***:::****** ENSP00000438689/1-678 EPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKE ENSMUSP00000099634/1-656 EPSSGSDVASIRSSAIPSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPIKDAATGAVKE ENSRNOP00000024973/1-655 EPSSGSDVASIRSSAVPSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPIKDAATGAVKE ENSCPOP00000014862/1-654 EPSSGSDAASIRSSAVPSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPITDAATGAVKE XP_004857422.1/1-655 EPSSGSDAASIRCSAMRSPCGKYYTLNGSKIWISNGGLADIFTVFAKTPVTDAATGVVKE *******.**** **: *************:******************:.*.***.*** ENSP00000438689/1-678 KITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHIL ENSMUSP00000099634/1-656 KITAFVVERSFGGVTHGLPEKKMGIKASNTSEVYFDGVKVPSENVLGEVGDGFKVAVNIL ENSRNOP00000024973/1-655 KITAFVVERSFGGVTHGLPEKKMGIKASNTSEVYFDGVKVPAENVLGEVGDGFKVAVNIL ENSCPOP00000014862/1-654 KITAFVVERSFGGVTHGPPEKKMGIKASNTAEVHFDGVRVPAENVLGEVGAGFKVAVHIL XP_004857422.1/1-655 KITAFVVERSFGGVTHGPPEKKMGIKASNTAEVYFDGVQVPSENVLGEVGGGFKVAVHIL *********.***:*** ************:**.****:**:******** *****::** ENSP00000438689/1-678 NNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMA ENSMUSP00000099634/1-656 NNGRFGMAATLAGTMKSLIAKAVDHATNRTQFGDKIHNFGVIQEKLARMAILQYVTESMA ENSRNOP00000024973/1-655 NNGRFGMAATLAGTMKAIIAKAVDHATNRTQFGDKIHNFGVIQEKLARMAILQYVTESMA ENSCPOP00000014862/1-654 NNGRFGMAATLAGTMKAIIAKAVDYATNRTQFGDKIHNFGLIQEKLARMAMLQYVTESMA XP_004857422.1/1-655 NNGRFGMAATLAGTMKTIIAKAVDHATNRTQFGDKIHNFGLIQEKLARMAMLQYVTESMA *********:*****: :******:********:******:********.:********* ENSP00000438689/1-678 YMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRI ENSMUSP00000099634/1-656 YMLSANMDQGFKDFQIEAAISKIFCSEAAWKVADECIQIMGGMGFMKEPGVERVLRDIRI ENSRNOP00000024973/1-655 YMLSANMDQGFKDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDIRI ENSCPOP00000014862/1-654 YMLSANMDRGYTDFQVEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDIRI XP_004857422.1/1-655 YMLSANMDRGYTDFQVEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDIRI **:*****:* .***:******** *******:************************:** ENSP00000438689/1-678 FRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGS ENSMUSP00000099634/1-656 FRIFEGANDILRLFVALQGCMDKGKELTGLGNALKNPFGNVGLLMGEAGKQLRRRTGIGS ENSRNOP00000024973/1-655 FRIFEGTNDILRLFVALQGCMDKGKELTGLGNALKNPLGNVGLLIGEASKQLRRRTGIGS ENSCPOP00000014862/1-654 FRIFEGTNDILRLFVALQGCTNKGKELSELGTALKNPLGNAGLLLTQAGKQLRRQVGLSS XP_004857422.1/1-655 FRIFEGTNDILRLFVALQGCMGKGKDLSALGNALKNPLGNAGLLLGEAGKQLRRQVGLSS ******:************* .***:*: **.*****:**.***: :*.*****:.*:.* ENSP00000438689/1-678 GLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYA ENSMUSP00000099634/1-656 GLSLSGIVHPELSRSGELAVQALDQFATVVEAKLVKHKKGIVNEQFLLQRLADGAIDLYA ENSRNOP00000024973/1-655 GLSLSGIVHPELSRSGELAVQALEQFATVVEAKLMKHKKGIVNEQFLLQRLADGAIDLYA ENSCPOP00000014862/1-654 GLSLGEVVHPELSRSGKLAVTALEQFASVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYT XP_004857422.1/1-655 GLSLSAVIHPELSRSGELAVKALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYS ****. ::********:*** **:***:******:************************: ENSP00000438689/1-678 MVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSI ENSMUSP00000099634/1-656 MVVVLSRASRSLSEGYPTAQHEKMLCDSWCIEAATRIRENMASLQSSPQHQELFRNFRSI ENSRNOP00000024973/1-655 MVVVLSRASRSLSEGYPTAQHEKMLCDSWCIEAATRIRENMASLQSNPQQQELFRNFRSI ENSCPOP00000014862/1-654 MVVVLSRASRSLSEGHPAAQHEKMLCDSWCIEAAARIRETMAALQSDPHQQELFRNFKSI XP_004857422.1/1-655 MVVVLSRASRSLSEGHPAAQHEKMLCDSWCIEAAARIRETMAALQSDPHQQELFRNFKSI ***************:*:*********:******:**** **:***.* :***:***:** ENSP00000438689/1-678 SKALVERGGVVTSNPLGF ENSMUSP00000099634/1-656 SKAMVENGGLVTGNPLGI ENSRNOP00000024973/1-655 SKAMVENGGLVTSNPLRV ENSCPOP00000014862/1-654 SKALVERGGIVTTNPLGF XP_004857422.1/1-655 SKALVERGGIVTSNPLGF ***:**.**:** *** .