CLUSTAL W(1.81) multiple sequence alignment ENSP00000263212/1-454 ---------------------------------------------------------MSS ENSMUSP00000027373/1-452 ---------------------------------------------------------MAS ENSRNOP00000002530/1-450 ---------------------------------------------------------MAS ENSCPOP00000014729/1-452 ---------------------------------------------------------ISC XP_004844115.1/1-508 MGHQKLPIESCFAISYSCDRRGTLALIPPPPALLHLHRVLMTVTSWSQLRATRDALGVTS ::. ENSP00000263212/1-454 GAPQKSSPMASGAEETPGFLDTLLQDFPALLNPEDPLPWKAPGTVLSQEEVEGELAELAM ENSMUSP00000027373/1-452 GAAQNSSQMACDS-EIPGFLDAFLQDFPAPLSLESPLPWKVPGTVLSQEEVEAELIELAL ENSRNOP00000002530/1-450 GAPQNSSQMACDG-EIPGFLDTLLQDFPAPLSLESPLPWKVPGTVLGQEEVEAELTELAM ENSCPOP00000014729/1-452 GAPQNSSPMACDA-EISDFLNTFLQDFPAPLNPESPLPWRFSGATLSREELEGELAELAM XP_004844115.1/1-508 GAPQNISQMACGS-EIPGFLDILFRDFPDPLSPESPLPWKALGTTLSQEEVEGELTELAM **.*: * **... * ..**: :::*** *. *.****: *:.*.:**:*.** ***: ENSP00000263212/1-454 GFLGSRKAPPPLAAALAHEAVSQLLQTDLSEFRKLPREEEEEEEDDDEEEKAPVTLLDAQ ENSMUSP00000027373/1-452 GFLGSRNAPPSFAVAVTHEAISQLLQTDLSEFKRLP--EQEEEEEEEEEEKALVTLLDAK ENSRNOP00000002530/1-450 GFLGSRNAPPAVAAAVTHEAISQLLQTDLSEFKRLP---EQEEEEEEEEERVLTTLLDAK ENSCPOP00000014729/1-452 GFLSSRNAPLPLAAALTHEAISQMLQADLSEFRKLPK-QEEEEGKDNEEMEATGTLLDTT XP_004844115.1/1-508 GFLGSRNVPLPLAAALTREAISHLLQADLSEFRKLP--SQEEEGDNEEEEKAPVTLLDAK ***.**:.* ..*.*:::**:*::**:*****::** ::** .::** .. ****: ENSP00000263212/1-454 SLAQSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLF ENSMUSP00000027373/1-452 GLARSFFNCLWKVCSQWQKQVPLTAQAPQWQWLVSIHAIRNTRRKMEDRHVSLPAFNHLF ENSRNOP00000002530/1-450 GLSRSFFNCLWEVCSQWQKRVPLTAQAPQRKWLVSIHAIRNTRRKMEDRHVSLPAFNHLF ENSCPOP00000014729/1-452 EVARSFFNQLWKVSSQWQKQVPVTARTPQKEWVVSIHAIRNARRRMEDRHVFLPAFNLLF XP_004844115.1/1-508 ELARSFFNQLWEVSGQWQKQVPVTARTPQREWVVSIHAIRNTRRRMEDRHVFLPAFNLLF :::**** **:*..****:**::*::.* :*:********:**:****** **:** ** ENSP00000263212/1-454 GLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFL ENSMUSP00000027373/1-452 GLSDSVHRAYFAVFDGHGGVDAARYASVHVHTNASHQPELRTNPAAALKEAFRLTDEMFL ENSRNOP00000002530/1-450 GLSDSVHRAYFAVFDGHGGVDAARYASVHVHTNASHQPELLTDPAAALKEAFRHTDQMFL ENSCPOP00000014729/1-452 GLSDSVDRAYFAVFDGHGGVDAARYAAVHVHVNAARQPKLLTDPAEALKEAFQHTDEMFL XP_004844115.1/1-508 GLSDPVDRAYFAVFDGHGGVDAATYAAVHVHVNAARHPKLRTDPTGALKEAFRHTDEMFL ****.*.**************** **:****.**:::*:* *:* **:***: **:*** ENSP00000263212/1-454 RKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARI ENSMUSP00000027373/1-452 QKAKRERLQSGTTGVCALIAGAALHVAWLGDSQVILVQQGRVVKLMEPHKPERQDEKARI ENSRNOP00000002530/1-450 QKAKRERLQSGTTGVCALITGAALHVAWLGDSQVILVQQGQVVKLMEPHKPERQDEKSRI ENSCPOP00000014729/1-452 WKAKRERLQSGTTGVCALIAGTNLHVAWLGDSQVFLVQQGQLIKLMEPHRPDQPEEWERI XP_004844115.1/1-508 LKARRERLQSGTTGVCVLVAGTTLHIAWLGDSQVILVQQGEVVKLMEPHRPERWDEKARI **:************.*::*: **:********:*****.::******:*:: :* ** ENSP00000263212/1-454 EALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACDGFF ENSMUSP00000027373/1-452 EALGGFVSLMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRELTGSEDYLLLACDGFF ENSRNOP00000002530/1-450 EALGGFVSLMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRELTGLEDYLLLACDGFF ENSCPOP00000014729/1-452 QRLGGFVTFLDCWRVNAALAVSRAIGDIFQKPYVSGDADSTSRELTGSEDYLLLACDGFF XP_004844115.1/1-508 EALGGIVYFMDCWRVNGTLAVSRAIGDVFQKPYVSGEADVASWELTGSEDYLLLACDGFF : ***:* :******.:*********:********:** :* *** ************ ENSP00000263212/1-454 DVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLEGG ENSMUSP00000027373/1-452 DVVPHHEVTGLVHGHLLRHKGNGMRIAEELVAVARDRGSHDNITVMVVFLREPLELLEGG ENSRNOP00000002530/1-450 DVVPHHEIPGLVHGHLLRQKGSGMHVAEELVAVARDRGSHDNITVMVVFLRDPLELLEGG ENSCPOP00000014729/1-452 DFVHLDEIASLVHSHLVKQEGDGAHVAEELVAVARDRGSSDNITVMVVFLRDPRELLESG XP_004844115.1/1-508 DVITFPEITSLVHSHLVKQQGNGLHVAEELVAEARERGSQDNITVMVVFLRDPRELLEDG *.: *: .**:.** :::*.* ::****** **:*** ***********:* ****.* ENSP00000263212/1-454 NQGEGDPQAEGRRQDLPSSLPEPE-TQAPPRS ENSMUSP00000027373/1-452 VQGTGDAQADVGSQDLSTGLSELEISNTSQRS ENSRNOP00000002530/1-450 GQGAGGAQADVGSQDLSTGLSELE-INTSQRS ENSCPOP00000014729/1-452 VQGPGNSQADVRSQDLSAGLSNPQ-TDTPQRN XP_004844115.1/1-508 VQGAGDSQAGVRSQDLSSGLSKPK-TSTPQRS ** *..** ***.:.*.: : .:. *.